Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine(1A) receptor agonist

Journal of Pharmacology and Experimental Therapeutics

Volumn 284, Issue 3, 1998, Pages 1082-1094

  De Vry, Jean ^a   Schohe Loop, Rudolf ^a,b   Heine, Hans Georg ^a,b   Greuel, Joachim M ^a   Mauler, Frank ^a   Schmidt, Bernard ^a   Sommermeyer, Henning ^a,b   Glaser, Thomas ^a,b  

^a MEDA Manufacturing GmbH   (Germany)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (7 METHOXY 1 NAPHTHYL) 4 [2 (2 THENOYLAMINO)ETHYL]PIPERAZINE; 2 [4 (CHROMAN 2 YLMETHYL)AMINO]BUTYL 1,1 DIOXO BENZOISOTHIAZOLONE; 2 CYANO 8 DIPROPYLAMINO 6,7,8,9 TETRAHYDRO 3H BENZ[E]INDOLE; 4 DIPROPYLAMINO 1,3,4,5 TETRAHYDROBENZ[CD]INDOLE 6 CARBOXAMIDE; 8 [4 (1,4 BENZODIOXAN 2 YLMETHYLAMINO)BUTYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALNESPIRONE; CHROMAN DERIVATIVE; LY 274607; LY 293284; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; OSEMOZOTAN; REPINOTAN; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DRUG DISCRIMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; ELECTROPHYSIOLOGY; HIPPOCAMPUS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; SUBSTANTIA NIGRA;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADENYLATE CYCLASE; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BENZOPYRANS; BODY TEMPERATURE; CYCLIC AMP; HIPPOCAMPUS; HUMANS; MALE; PHOSPHATIDYLINOSITOLS; RAPHE NUCLEI; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN AGONISTS; THIAZOLES;

EID: 0031910091     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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