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Volumn 22, Issue 4, 1997, Pages 341-349

BAY x 3702. Neuroprotectant, 5-HT(1A) agonist

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALBUMIN; ALPHA1 GLYCOPROTEIN; CALCIUM ION; EXCITATORY AMINO ACID; GLUTAMATE RECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; REPINOTAN; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

EID: 0030814402     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (47)

References (47)
  • 2
    • 0025030162 scopus 로고
    • An overview of the epidemiology of stroke
    • Wolf, P.A. An overview of the epidemiology of stroke. Stroke 1990, 21(Suppl. II): 4-6.
    • (1990) Stroke , vol.21 , Issue.2 SUPPL. , pp. 4-6
    • Wolf, P.A.1
  • 3
    • 0004949212 scopus 로고
    • Frequency and determinants of stroke
    • M. Fisher (Ed.), Mosby-Year Book Europe, London
    • Sacco, R.L. Frequency and determinants of stroke. In: Clinical Atlas of Cerebrovascular Disease, M. Fisher (Ed.), Mosby-Year Book Europe, London, 1994, 1.1-1.16.
    • (1994) Clinical Atlas of Cerebrovascular Disease , pp. 11-116
    • Sacco, R.L.1
  • 5
    • 0021338492 scopus 로고
    • Epidemiologic features of head injury in predominantly rural population
    • Jagger, J., Levine, J.I., Jane, J.A. et al. Epidemiologic features of head injury in predominantly rural population. J Trauma 1984, 24: 40-4.
    • (1984) J Trauma , vol.24 , pp. 40-44
    • Jagger, J.1    Levine, J.I.2    Jane, J.A.3
  • 6
    • 0019180454 scopus 로고
    • The national head and spinal cord injury survey: Major findings
    • Kalsbeek, W.D., McLaurin, R.L., Harris, B.S. et al. The national head and spinal cord injury survey: Major findings. J Neurosurg 1980, 53: 19-31.
    • (1980) J Neurosurg , vol.53 , pp. 19-31
    • Kalsbeek, W.D.1    McLaurin, R.L.2    Harris, B.S.3
  • 7
    • 0002749256 scopus 로고
    • The epidemiology of head injury
    • R. Braakman (Ed.), Elsevier, New York
    • Jennet, B., Frankowski, R.F. The epidemiology of head injury. In: Handbook of Clinical Neurology, R. Braakman (Ed.), Elsevier, New York, 1990, 1-16.
    • (1990) Handbook of Clinical Neurology , pp. 1-16
    • Jennet, B.1    Frankowski, R.F.2
  • 8
    • 0026228194 scopus 로고
    • The excitotoxin hypothesis in relation to cerebral ischemia
    • Benveniste, H. The excitotoxin hypothesis in relation to cerebral ischemia. Cerebrovasc Brain Metab Rev 1991, 3: 213-45.
    • (1991) Cerebrovasc Brain Metab Rev , vol.3 , pp. 213-245
    • Benveniste, H.1
  • 9
    • 0025178827 scopus 로고
    • Evidence of a differential sensitivity of monoamines neurotransmission to ischemia: An intracerebral dialysis study
    • Sarna, G.S., Obrenovitch, T.P., Matsumoto, T. et al. Evidence of a differential sensitivity of monoamines neurotransmission to ischemia: An intracerebral dialysis study. J Neurochem 1990, 55: 937-40.
    • (1990) J Neurochem , vol.55 , pp. 937-940
    • Sarna, G.S.1    Obrenovitch, T.P.2    Matsumoto, T.3
  • 10
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1: 623-34.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 11
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman, S.M., Olney, J.W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann Neurol 1986, 19: 105-11.
    • (1986) Ann Neurol , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 12
    • 0025603178 scopus 로고
    • Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion
    • Butcher, S.P., Bullock, R., Graham, D.I., McCulloch, J. Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke 1990, 21: 1727-33.
    • (1990) Stroke , vol.21 , pp. 1727-1733
    • Butcher, S.P.1    Bullock, R.2    Graham, D.I.3    McCulloch, J.4
  • 13
    • 0026777223 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology
    • Siesjö, B.K. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. J Neurosurg 1992, 77: 169-84.
    • (1992) J Neurosurg , vol.77 , pp. 169-184
    • Siesjö, B.K.1
  • 14
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanism of damage and treatment
    • Siesjö, B.K. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanism of damage and treatment. J Neurosurg 1992, 77: 337-54.
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjö, B.K.1
  • 15
    • 0024418136 scopus 로고
    • Calcium, neuronal hyperexcitability and ischemic injury
    • Meyer, F.B. Calcium, neuronal hyperexcitability and ischemic injury. Brain Res Rev 1989, 14: 227-43.
    • (1989) Brain Res Rev , vol.14 , pp. 227-243
    • Meyer, F.B.1
  • 16
    • 0004260631 scopus 로고
    • Excitotoxicity
    • B.S. Meldrum (Ed.), Blackwell, Oxford
    • Choi, D.W. Excitotoxicity. In: Excitatory Amino Acid Antagonists, B.S. Meldrum (Ed.), Blackwell, Oxford, 1991, 216-36.
    • (1991) Excitatory Amino Acid Antagonists , pp. 216-236
    • Choi, D.W.1
  • 17
    • 0002631763 scopus 로고
    • 1A receptors
    • S.M. Stahl, M. Gastpar, J.M. Keppel Hesselink and J. Traber (Eds.), Raven Press, New York
    • 1A Receptors in Depression and Anxiety, S.M. Stahl, M. Gastpar, J.M. Keppel Hesselink and J. Traber (Eds.), Raven Press, New York, 1992, 35-53.
    • (1992) 1A Receptors in Depression and Anxiety , pp. 35-53
    • Glaser, T.1    De Vry, J.2
  • 18
    • 0028990742 scopus 로고
    • 1A receptor agonists: Recent developments and controversial issues
    • 1A receptor agonists: Recent developments and controversial issues. Psychopharmacology 1995, 121: 1-26.
    • (1995) Psychopharmacology , vol.121 , pp. 1-26
    • De Vry, J.1
  • 19
    • 0029982857 scopus 로고    scopus 로고
    • 1A receptors in psychopathology and the mechanism of action of clinically effective therapeutic agents
    • 1A receptors in psychopathology and the mechanism of action of clinically effective therapeutic agents. Drug News Perspect 1996, 9: 270-80.
    • (1996) Drug News Perspect , vol.9 , pp. 270-280
    • De Vry, J.1
  • 21
    • 0026710095 scopus 로고
    • 1A receptors in the rat hippocampus and cortex
    • 1A receptors in the rat hippocampus and cortex. Drug Dev Res 1992, 26: 275-86.
    • (1992) Drug Dev Res , vol.26 , pp. 275-286
    • Andrade, R.1
  • 22
    • 0023250760 scopus 로고
    • Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin
    • Colino, A., Halliwell, J.V. Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin Nature 1987, 328: 73-7.
    • (1987) Nature , vol.328 , pp. 73-77
    • Colino, A.1    Halliwell, J.V.2
  • 23
    • 0023233048 scopus 로고
    • Two distinct effects of 5-hydroxytriptamine on single cortical neurons
    • Davies, M.F., Deisz, R.A., Prince, D.A., Peroutka, S.J. Two distinct effects of 5-hydroxytriptamine on single cortical neurons. Brain Res 1987, 423: 347-52.
    • (1987) Brain Res , vol.423 , pp. 347-352
    • Davies, M.F.1    Deisz, R.A.2    Prince, D.A.3    Peroutka, S.J.4
  • 24
    • 0025856979 scopus 로고
    • 1-like receptors on glutamatergic terminals inhibit N-methyl-D-aspartate-induced cyclic GMP production in rat cerebellar slices
    • 1-like receptors on glutamatergic terminals inhibit N-methyl-D-aspartate-induced cyclic GMP production in rat cerebellar slices. J Pharmacol Exp Ther 1991, 257: 1184-8.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 1184-1188
    • Raiteri, M.1    Maura, G.2    Barzizza, A.3
  • 25
    • 0002073872 scopus 로고
    • 1A receptor agonists on the glutamate-induced rise in cytosolic calcium concentration as well as on calcium and potassium currents in hippocampal neurons
    • J. Kriegelstein and H. Oberpichler-Schwenk (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart
    • 1A receptor agonists on the glutamate-induced rise in cytosolic calcium concentration as well as on calcium and potassium currents in hippocampal neurons. In: Pharmacology of Cerebral Ischemia, J. Kriegelstein and H. Oberpichler-Schwenk (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart, 1994, 89-97.
    • (1994) Pharmacology of Cerebral Ischemia , pp. 89-97
    • Ruppalla, K.1    Jakob, R.2    Kriegelstein, J.3
  • 26
  • 27
    • 0025647630 scopus 로고
    • 1A agonists: A new therapeutic principle for stroke treatment
    • 1A agonists: A new therapeutic principle for stroke treatment. Stroke 1990, 21(Suppl. IV): 161-3.
    • (1990) Stroke , vol.21 , Issue.4 SUPPL. , pp. 161-163
    • Bielenberg, G.W.1    Burkhardt, M.2
  • 28
    • 0025126232 scopus 로고
    • 1A agonists show neuroprotectant activity in rats and mice
    • 1A agonists show neuroprotectant activity in rats and mice. Eur J Pharmacol 1990, 183: 1953-4.
    • (1990) Eur J Pharmacol , vol.183 , pp. 1953-1954
    • Bielenberg, G.W.1    Burkhardt, M.2
  • 29
    • 0025685410 scopus 로고
    • 1A agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil
    • 1A agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil. Stroke 1990, 21(Suppl. IV): 164-6.
    • (1990) Stroke , vol.21 , Issue.4 SUPPL. , pp. 164-166
    • Bode-Greuel, K.M.1    Klisch, J.2    Horváth, E.3
  • 30
    • 0343843197 scopus 로고
    • 1A receptor agonists as neuroprotective agents in cerebral ischemia
    • J. Krieglstein and H. Oberpichler (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart
    • 1A receptor agonists as neuroprotective agents in cerebral ischemia. In: Pharmacology of Cerebral Ischemia, J. Krieglstein and H. Oberpichler (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart, 1990, 485-91.
    • (1990) Pharmacology of Cerebral Ischemia , pp. 485-491
    • Bode-Greuel, K.M.1    Klisch, J.2    Glaser, T.3    Traber, J.4
  • 32
    • 0002317332 scopus 로고
    • 1A-agonist CM57493 on infarct area, infarct volume and hippocampal neuronal damage after focal and global cerebral ischemia in mice and rats
    • J. Krieglstein and H. Oberpichler (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart
    • 1A-agonist CM57493 on infarct area, infarct volume and hippocampal neuronal damage after focal and global cerebral ischemia in mice and rats. In: Pharmacology of Cerebral Ischemia, J. Krieglstein and H. Oberpichler (Eds.), Wissenschaftliche Verlagsgesellschaft, Stuttgart, 1990, 493-7.
    • (1990) Pharmacology of Cerebral Ischemia , pp. 493-497
    • Nuglisch, J.1    Karkoutly, C.2    Peruche, B.3
  • 33
    • 0026003258 scopus 로고
    • 1A receptor agonists in rodent models of focal and global cerebral ischemia
    • 1A receptor agonists in rodent models of focal and global cerebral ischemia. Eur J Pharmacol 1991, 203: 213-22.
    • (1991) Eur J Pharmacol , vol.203 , pp. 213-222
    • Prehn, J.H.M.1    Backhauss, C.2    Karkoutly, C.3
  • 34
    • 0027493547 scopus 로고
    • Effects of serotonergic drugs in experimental brain ischemia: Evidence for a protective role of serotonin in cerebral ischemia
    • Prehn, J.H.M., Welsch, M., Backhauss, C. et al. Effects of serotonergic drugs in experimental brain ischemia: Evidence for a protective role of serotonin in cerebral ischemia. Brain Res 1993, 630: 10-20.
    • (1993) Brain Res , vol.630 , pp. 10-20
    • Prehn, J.H.M.1    Welsch, M.2    Backhauss, C.3
  • 35
    • 0026733437 scopus 로고
    • BMY-14802 protects against ischemia-induced neuronal damage in the gerbil
    • Contreras, P.C., Gray, N.M., Ragan, D.M., Lanthorn, T.H. BMY-14802 protects against ischemia-induced neuronal damage in the gerbil. Life Sci 1992, 51: 1145-9.
    • (1992) Life Sci , vol.51 , pp. 1145-1149
    • Contreras, P.C.1    Gray, N.M.2    Ragan, D.M.3    Lanthorn, T.H.4
  • 38
    • 0002707323 scopus 로고
    • 1A receptors in anxiety
    • M. Briley and S.E. File (Eds.), MacMillan Press, London
    • 1A receptors in anxiety. In: New Concepts in Anxiety, M. Briley and S.E. File (Eds.), MacMillan Press, London, 1991, 94-129.
    • (1991) New Concepts in Anxiety , pp. 94-129
    • De Vry, J.1    Glaser, T.2    Schuurman, T.3
  • 39
    • 0029132789 scopus 로고
    • A pharmacological profile of the selective silent 5-HT1A receptor antagonist WAY-100635
    • Forster, E.A., Cliffe, I.A., Bill, D.J. et al. A pharmacological profile of the selective silent 5-HT1A receptor antagonist WAY-100635. Eur J Pharmacol 1995, 281: 81-8.
    • (1995) Eur J Pharmacol , vol.281 , pp. 81-88
    • Forster, E.A.1    Cliffe, I.A.2    Bill, D.J.3
  • 41
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • Bederson, J.B., Pitts, L.H., Tsuji, M. et al. Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination. Stroke 1986, 17: 472-6.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3
  • 42
    • 0002254106 scopus 로고
    • Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area
    • Koizumi, J., Yoshida, Y., Nakazawa, T., Ooneda, G. Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke 1986, 8: 1-8.
    • (1986) Jpn J Stroke , vol.8 , pp. 1-8
    • Koizumi, J.1    Yoshida, Y.2    Nakazawa, T.3    Ooneda, G.4
  • 43
    • 0024414013 scopus 로고
    • Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion
    • Nagasawa, H., Kogure, K. Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke 1989, 20: 1037-43.
    • (1989) Stroke , vol.20 , pp. 1037-1043
    • Nagasawa, H.1    Kogure, K.2
  • 44
    • 0028167832 scopus 로고
    • The omega-conopeptide SNX-111, an N-type calcium channel blocker, dramatically ameliorates brain damage due to transient focal ischemia
    • Zhao, Q., Smith, M.-L., Siesjö, B.K. The omega-conopeptide SNX-111, an N-type calcium channel blocker, dramatically ameliorates brain damage due to transient focal ischemia. Acta Physiol Scand 1994, 150: 459-61.
    • (1994) Acta Physiol Scand , vol.150 , pp. 459-461
    • Zhao, Q.1    Smith, M.-L.2    Siesjö, B.K.3
  • 45
    • 0025130511 scopus 로고
    • Ischemic brain damage in a model of acute subdural hematoma
    • Miller, J.D., Bullock, R., Graham, D.I. et al. Ischemic brain damage in a model of acute subdural hematoma. Neurosurgery 1990, 27: 433-9.
    • (1990) Neurosurgery , vol.27 , pp. 433-439
    • Miller, J.D.1    Bullock, R.2    Graham, D.I.3
  • 47
    • 0028204887 scopus 로고
    • The molecular basis of genetic polymorphisms of drug metabolism
    • Meyer, U.A. The molecular basis of genetic polymorphisms of drug metabolism. J Pharm Pharmacol 1994, 46: 409-15.
    • (1994) J Pharm Pharmacol , vol.46 , pp. 409-415
    • Meyer, U.A.1


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