Mechanism of inducible nitric oxide synthase inactivation by aminoguanidine and L-N6-(1-Iminoethyl)lysine

Biochemistry

Volumn 37, Issue 14, 1998, Pages 4844-4852

  Bryk, Ruslana ^a   Wolff, Donald J ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME MODIFICATION; PRIORITY JOURNAL; RADIOACTIVITY;

ANIMALS; CARBON ISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; GUANIDINES; KINETICS; LYSINE; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; SPECTROMETRY, FLUORESCENCE;

EID: 0032492716     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972065t     Document Type: Article

References (35)

1. Kwon N. S., Nathan, C. F., Gilker, C., Griffith, O. W., Matthews, D. E., and Stuehr, D. J. (1990) J. Biol. Chem. 265, 13442-13445.
2. Masters, B. S. S., McMillan, K., Sheta, E. A., Nishimura, J. S., Roman, L. J., and Martasek, P. (1996) FASEB J. 10, 552-558.
3. Stuehr, D. J. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 339-359.
4. MacMicking, J., Xie, Q., and Nathan, C. (1997) Annu. Rev. Immunol. 15, 323-350.
5. Moncada, S. and Higgs, E. A. (1995) FASEB J. 9, 1319-1330.
6. Connor, J. R., Manning, P. T., Settle, S. L., Moore, W. M., Jerome, G. M., Webber, R. K., Tjoeng, F. S., and Currie, M. G. (1995) Eue. J. Pharm. 273, 15-24.
7. Zhao, W., Tilton, R. G., Corbett, J. A., McDaniel, M. L., Misko, T. P., Williamson, J. R., Cross, A. H., and Hickey, W. F. (1996) J. Neuroimmunol. 64, 123-133.
8. Moore, W. M., Webber, R. K., Jerome, G. M., Tjoeng, F. S., Misko, T. P., and Currie, M. G. (1994) J. Med. Chem. 37, 3886-3888.
9. Wolff, D. J., and Lubeskie, A. (1995) Arch. Biochem. Biophys. 316, 290-301.
10. Silverman, R. B. (1988) Mechanism-based Enzyme Inactivation: Chemistry and Enzymology Vol. 1, pp 1-27, CRC Press, Boca Raton, FL.
11. Osawa, Y. and Pohl, L. R. (1989) Chem. Res. Tox. 2, 131-141.
12. Wolff, D. J. and Gribin, B. J. (1994) Arch. Biochem. Biophys. 311, 293-299.
13. Wolff, D. J. and Datto, G. A. (1992) Biochem. J. 285, 201-206.
14. Morrison, G. R. (1965) Anal. Chem. 37, 1124-1126.
15. Mayer, B., Klatt, P., Harteneck, C., List, B. M., Werner, E. R., and Schmidt, K. (1996) in Nitric Oxide Synthase: Characterization and Functional Analysis (Maines, M. D., Ed.) pp 130-139, Academic Press, San Diego, CA.
16. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
17. Marletta, M. A. (1993) J. Biol. Chem. 268, 12231-12234.
18. Xie, Q., Leung, M., Fuortes, M., Sassa, S., and Nathan, C. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 4891-4896.
19. Olken, N. M., Osawa, Y., and Marietta, M. A. (1994) Biochemistry 33, 14784-14791.
20. Cho, H. J., Martin, E., Xie, Q., Sassa, S., and Nathan, C. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 11514-11518.
21. Walsh, C. T. (1984) Annu. Rev. Biochem. 53, 493-535.
22. Ortiz de Montellano, P. R. (1990) Pharm. Therap. 48, 95-120.
23. Ortiz de Montellano, P. R., and Correia, M. A. (1983) Annu. Rev. Pharmacol. Toxicol. 23, 481-503.
24. Ortiz de Montellano, P. R., and Komives, E. A. (1985) J. Biol. Chem. 260, 3330-3336.
25. De Matteis, F., Hollands, C., Gibbs, A. H., de Sa, N., and Rizzardini, M. (1982) FEBS Lett. 145, 87-92.
26. Sennequier, N., and Stuehr, D. J. (1996) Biochemistry 35, 5883-5892.
27. Halpert, J. (1981) Biochem. Pharmacol. 30, 875-881.
28. Davies, H. W., Satoh, H., Schulick, R. D., and Pohl, L. R. (1985) Biochem. Pharmacol. 34, 3203-3206.
29. He, K., He, Y. A., Szklarz, G. D., Halpert, J. R., and Correia, M. A. (1996) J. Biol. Chem. 271, 25864-25872.
30. Manno, M., King, L. J., de Matteis, F. (1989) Xenobiot. 19, 1023-1035.
31. Guengerich, P. F. (1978) Biochemistry 17, 3633-3639.
32. Baek, K. J., Thiel, B. A., Lucas, S., and Stuehr, D. J. (1993) J. Biol. Chem. 268, 21120-21129.
33. Albakri, Q. A., and Stuehr, D. J. (1996) J. Biol. Chem. 271, 5414-5421.
34. Ortiz de Montellano, P. R., and Reich N. O. (1986) in Cvtochrome P-450: Structure, Mechanism, and Biochemistry (Ortiz de Montellano, P. R., Ed.) pp 273-314, Plenum Press, New York.
35. Berka, V., Chen, P.-F., and Tsai, A.-L. (1996) J. Biol. Chem. 271, 33293-33300.