Production and selection of antigen-specific fully human monoclonal antibodies from mice engineered with human Ig loci

Advanced Drug Delivery Reviews

Volumn 31, Issue 1-2, 1998, Pages 33-42

  Jakobovits, Aya ^a  

^a Abgenix Inc   (United States)

Author keywords

Antibody therapy; B cell development; ES cells; Immunoglobulin; Transgene; Yeast artificial chromosome

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; GENETIC ENGINEERING; IMMUNIZATION; MONOCLONAL ANTIBODIES;

IMMUNOGLOBULINS;

CONTROLLED DRUG DELIVERY;

IMMUNOGLOBULIN ANTIBODY; MONOCLONAL ANTIBODY;

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; GENETIC ENGINEERING; HUMAN; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOTHERAPY; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; YEAST ARTIFICIAL CHROMOSOME;

EID: 0032489887     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(97)00092-6     Document Type: Review

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