Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II

Journal of Biological Chemistry

Volumn 272, Issue 13, 1997, Pages 8243-8249

  Han, Jin Hua ^a   Van Deerlin, Vivianna M D ^a,b   Tollefsen, Douglas M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN COFACTOR II; THROMBIN;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; DISSOCIATION; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; HUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

ARGININE; BINDING SITES; DERMATAN SULFATE; HEPARIN; HEPARIN COFACTOR II; HIRUDINS; HUMANS; KINETICS; LEUCINE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SODIUM DODECYL SULFATE; THROMBIN;

EID: 0030934038     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.13.8243     Document Type: Article

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