Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 3, 1998, Pages 277-280

  Bouygues, M ^a,b   Medou, M ^a,b   Quelever G ^a,b   Chermann, J C ^b   Camplo, M ^a,b   Kraus, J L ^a,b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; POLYPEPTIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTITION COEFFICIENT; REACTION ANALYSIS;

ANTI-HIV AGENTS; CELL LINE; DIPEPTIDES; HUMANS; MICROBIAL SENSITIVITY TESTS; PROLINE; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032477691     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00006-7     Document Type: Article

References (11)

1. 1. Beaulieu, P.; Wernic, D.; Abraham, A.; Anderson, P.; Bogri, T.; Bousquet, Y., Croteau, G.; Guse, I.; Lamarred, D.; Liard, F.; Paris, W.; Thibeault, D.; Pau, S.; Tong, L. J. Med. Chem. 1997, 40, 2164-2176.
2. 2. Navia, M.; Heimbach, J.; Herber, W.; Leu, C.; Mcheevern, B.; Springer, J.; Sigal, I.; Dark, P.; Fitzgerald, P. Nature 1989, 357, 615-620.
3. 3. Scheinder, J.; Kent, S. Cell 1988, 54, 363-368.
4. 4. Hansen, J.; Billich, S.; Schulze, T.; Sukrow, S.; Moelling, K. EMBO. J. 1988, 7, 1785-1791.
5. 5. Darke, P.; Nutt, R.; Brady, S.; Garsky, V.; Ciccarone, T.; Leu, C.; Lumma, P., Freidinser, R.; Veber, D.; Sigal, J. Biochem. Biophys. Res. Comm. 1988, 156, 287-303.
6. 6. Pearl, L.; Taylor, W. Nature 1987, 328, 482.
7. 7. Siedlecka, R; Skarzewski, J.; Mlochowski, J. Tetrahedron. Lett. 1990, 31, 2177-2180.
8. 8. Augustyns, K.J.L.; Lambeir, A.M.; Borloo, M.; De Meester, I.; Vedernika, I.; Vanhoof, G.; Hendriks, D.; Scharpe, S.; Haemers, A. Eur. J. Med. Chem. 1997, 32, 301-309.
9. 9. Welch, J.T.; Lin, J. Tetrahedron. 1996, 52, 291-304.
10. 10. Thompson, W.; Fitzgerald, P.; Holloway, K.; Emini, E.; Darke, P.; McKeever, B., Schleif, W.; Quintero, J.; Zugay, J.; Tucker, T.; Schwering, J., Homnick, C.; Nunberg, J.; Springer, J.; Huff, J. J. Med. Chem. 1992, 35, 1685-1701.
11. 11. Smith, A.; Hirschmann, R.; Pasternak, A.; Yao, W., Sprengeler, P. J. Med. Chem. 1997, 40, 2440-2444.