Differential effects of S6 mutations on binding of quinidine and 4- aminopyridine to rat isoform of Kv1.4: Common site but different Factors in determining blockers' binding affinity

Journal of Pharmacology and Experimental Therapeutics

Volumn 287, Issue 1, 1998, Pages 332-343

  Zhang, Hailing ^a   Zhu, Bing ^a   Yao, Jian An ^a   Tseng, Gea Ny ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; PROTEIN SUBUNIT; QUINIDINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; XENOPUS LAEVIS;

4-AMINOPYRIDINE; ANIMALS; BINDING SITES; FEMALE; ION CHANNEL GATING; KV1.4 POTASSIUM CHANNEL; MUTATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; QUINIDINE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 0032469107     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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