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Volumn 16, Issue 1, 1998, Pages 35-41

What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ALZHEIMER DISEASE; ARTICLE; CELL VIABILITY; HUMAN; NERVE DEGENERATION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0032465384     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-0618(98)00061-1     Document Type: Article
Times cited : (28)

References (90)
  • 1
  • 2
    • 0000293742 scopus 로고
    • In: Rottenberg, D.A., Hochberg, F.H. (Eds.)
    • Alzheimer, A., 1907. In: Rottenberg, D.A., Hochberg, F.H. (Eds.), Allg. Z. Psychiatrie Psychisch-Gerichtliche Medizin 64, 146-148. Translated in Neurological Classics in Modern Translation, 1977. Hafner Press, New York, pp. 41-43.
    • (1907) Allg. Z. Psychiatrie Psychisch-Gerichtliche Medizin , vol.64 , pp. 146-148
    • Alzheimer, A.1
  • 3
    • 0006730128 scopus 로고
    • Hafner Press, New York
    • Alzheimer, A., 1907. In: Rottenberg, D.A., Hochberg, F.H. (Eds.), Allg. Z. Psychiatrie Psychisch-Gerichtliche Medizin 64, 146-148. Translated in Neurological Classics in Modern Translation, 1977. Hafner Press, New York, pp. 41-43.
    • (1977) Translated in Neurological Classics in Modern Translation , pp. 41-43
  • 6
    • 0029145084 scopus 로고
    • Are reactive oxygen species involved in Alzheimer's disease?
    • Benzi G., Moretti A. Are reactive oxygen species involved in Alzheimer's disease? Neurobiol. Aging. 16:1995;661-674.
    • (1995) Neurobiol. Aging , vol.16 , pp. 661-674
    • Benzi, G.1    Moretti, A.2
  • 7
    • 0021261962 scopus 로고
    • Aluminum effect on slow axonal transport: A novel impairment of neurofilament transport
    • Bizzi A., Crane R.C., Autilio-Gambetti L., Gambetti P. Aluminum effect on slow axonal transport: a novel impairment of neurofilament transport. J. Neurosci. 4:1984;722-731.
    • (1984) J. Neurosci. , vol.4 , pp. 722-731
    • Bizzi, A.1    Crane, R.C.2    Autilio-Gambetti, L.3    Gambetti, P.4
  • 8
    • 0014313861 scopus 로고
    • The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
    • Blessed G., Tomlinson B.E., Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Brit. J. Psychiat. 114:1968;797-811.
    • (1968) Brit. J. Psychiat. , vol.114 , pp. 797-811
    • Blessed, G.1    Tomlinson, B.E.2    Roth, M.3
  • 10
    • 0026073725 scopus 로고
    • Alzheimer's disease and cellular aging: Membrane-related events as clues to primary mechanisms
    • Bosman G.J., Bartholomeus I.G., de Grip W.J. Alzheimer's disease and cellular aging: membrane-related events as clues to primary mechanisms. Gerontology. 37:1991;95-112.
    • (1991) Gerontology , vol.37 , pp. 95-112
    • Bosman, G.J.1    Bartholomeus, I.G.2    De Grip, W.J.3
  • 11
    • 0022601241 scopus 로고
    • Aluminosilicates and senile plaque formation in Alzheimer's disease
    • Candy J.M., Oakley A.E., Klinowski J. et al. Aluminosilicates and senile plaque formation in Alzheimer's disease. Lancet. 1:1986;354-357.
    • (1986) Lancet , vol.1 , pp. 354-357
    • Candy, J.M.1    Oakley, A.E.2    Klinowski, J.3
  • 13
    • 0030823756 scopus 로고    scopus 로고
    • Acceleration of amyloid fibril formation by specific binding of Aβ-(1-40) peptide to ganglioside-containing membrane vesicles
    • Choo-Smith L.P., Garzon-Rodriguez W., Glabe C.G., Surewicz W.K. Acceleration of amyloid fibril formation by specific binding of Aβ-(1-40) peptide to ganglioside-containing membrane vesicles. J. Biol. Chem. 272:1997;22987-22990.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22987-22990
    • Choo-Smith, L.P.1    Garzon-Rodriguez, W.2    Glabe, C.G.3    Surewicz, W.K.4
  • 14
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder E.H., Saunders A.M., Strittmatter W.J. et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 15
    • 0015913994 scopus 로고
    • Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration
    • Crapper D.R., Krishnan S.S., Dalton A.J. Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration. Science. 180:1973;511-513.
    • (1973) Science , vol.180 , pp. 511-513
    • Crapper, D.R.1    Krishnan, S.S.2    Dalton, A.J.3
  • 16
    • 0017260845 scopus 로고
    • Aluminium, neurofibrillary degeneration and Alzheimer's disease
    • Crapper D.R., Krishnan S.S., Quittkat S. Aluminium, neurofibrillary degeneration and Alzheimer's disease. Brain. 99:1976;67-80.
    • (1976) Brain , vol.99 , pp. 67-80
    • Crapper, D.R.1    Krishnan, S.S.2    Quittkat, S.3
  • 18
    • 18144453796 scopus 로고    scopus 로고
    • Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
    • DeWitt D.A., Perry G., Cohen M., Doller C., Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp. Neurol. 149:1998;329-340.
    • (1998) Exp. Neurol. , vol.149 , pp. 329-340
    • Dewitt, D.A.1    Perry, G.2    Cohen, M.3    Doller, C.4    Silver, J.5
  • 19
    • 0026635173 scopus 로고
    • Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid
    • Frautschy S.A., Cole G.M., Baird A. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am. J. Pathol. 140:1992;1389-1399.
    • (1992) Am. J. Pathol. , vol.140 , pp. 1389-1399
    • Frautschy, S.A.1    Cole, G.M.2    Baird, A.3
  • 20
    • 0027217679 scopus 로고
    • The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development
    • Goedert M., Jakes R., Crowther R.A. et al. The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proc. Natl. Acad. Sci. USA. 90:1993;5066-5070.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5066-5070
    • Goedert, M.1    Jakes, R.2    Crowther, R.A.3
  • 21
    • 0026573467 scopus 로고
    • Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study
    • Good P.F., Perl D.P., Bierer L.M., Schmeidler J. Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann. Neurol. 31:1992;286-292.
    • (1992) Ann. Neurol. , vol.31 , pp. 286-292
    • Good, P.F.1    Perl, D.P.2    Bierer, L.M.3    Schmeidler, J.4
  • 22
    • 0002403702 scopus 로고    scopus 로고
    • Dietary links to Alzheimer's disease
    • Grant W.B. Dietary links to Alzheimer's disease. Alz. Dis. Rev. 2:1997;42-55.
    • (1997) Alz. Dis. Rev. , vol.2 , pp. 42-55
    • Grant, W.B.1
  • 23
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy J.A., Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science. 256:1992;184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 24
    • 0028807137 scopus 로고
    • Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation
    • Hensley K., Hall N., Subramaniam R. et al. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J. Neurochem. 65:1995;2146-2156.
    • (1995) J. Neurochem. , vol.65 , pp. 2146-2156
    • Hensley, K.1    Hall, N.2    Subramaniam, R.3
  • 25
    • 0031026879 scopus 로고    scopus 로고
    • Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study
    • Hofman A., Ott A., Breteler M.M. et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study. Lancet. 349:1997;151-154.
    • (1997) Lancet , vol.349 , pp. 151-154
    • Hofman, A.1    Ott, A.2    Breteler, M.M.3
  • 26
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
    • Hsiao K., Chapman P., Nilsen S. et al. Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3
  • 28
    • 15844384255 scopus 로고    scopus 로고
    • The effects of repetitive mild brain injury on cytoskeletal protein and behavior
    • Kanayama G., Takeda M., Niigawa H. et al. The effects of repetitive mild brain injury on cytoskeletal protein and behavior. Methods Findings Exp. Clin. Pharmacol. 18:1996;105-115.
    • (1996) Methods Findings Exp. Clin. Pharmacol. , vol.18 , pp. 105-115
    • Kanayama, G.1    Takeda, M.2    Niigawa, H.3
  • 29
    • 0025665181 scopus 로고
    • The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease
    • Kawai M., Kalaria R.N., Harik S.I., Perry G. The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am. J. Pathol. 137:1990;1435-1446.
    • (1990) Am. J. Pathol. , vol.137 , pp. 1435-1446
    • Kawai, M.1    Kalaria, R.N.2    Harik, S.I.3    Perry, G.4
  • 30
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian Z.S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1985;1097-1105.
    • (1985) Arch. Neurol. , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 32
    • 0026451874 scopus 로고
    • Absence of aluminium in neuritic plaque cores in Alzheimer's disease
    • Landsberg J.P., McDonald B., Watt F. Absence of aluminium in neuritic plaque cores in Alzheimer's disease. Nature. 360:1992;65-68.
    • (1992) Nature , vol.360 , pp. 65-68
    • Landsberg, J.P.1    McDonald, B.2    Watt, F.3
  • 33
    • 0023891743 scopus 로고
    • The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy
    • Mann D.M.A., Marcyniuk B., Yates P.O., Neary D., Snowden J.S. The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy. Neuropathol. Appl. Neurobiol. 14:1988;177-195.
    • (1988) Neuropathol. Appl. Neurobiol. , vol.14 , pp. 177-195
    • Mann, D.M.A.1    Marcyniuk, B.2    Yates, P.O.3    Neary, D.4    Snowden, J.S.5
  • 34
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery W.R. Oxidative stress hypothesis in Alzheimer's disease. Free Rad. Biol. Med. 23:1997;134-147.
    • (1997) Free Rad. Biol. Med. , vol.23 , pp. 134-147
    • Markesbery, W.R.1
  • 36
    • 0024364877 scopus 로고
    • Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease
    • Masliah E., Terry R.D., DeTeresa R.M., Hansen L.A. Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neurosci. Lett. 103:1989;234-239.
    • (1989) Neurosci. Lett. , vol.103 , pp. 234-239
    • Masliah, E.1    Terry, R.D.2    Deteresa, R.M.3    Hansen, L.A.4
  • 37
    • 0025600931 scopus 로고
    • Diffuse plaques do not accentuate synapse loss in Alzheimer's disease
    • Masliah E., Terry R.D., Mallory M., Alford M., Hansen L.A. Diffuse plaques do not accentuate synapse loss in Alzheimer's disease. Am. J. Pathol. 137:1990;1293-1297.
    • (1990) Am. J. Pathol. , vol.137 , pp. 1293-1297
    • Masliah, E.1    Terry, R.D.2    Mallory, M.3    Alford, M.4    Hansen, L.A.5
  • 39
    • 0029940648 scopus 로고    scopus 로고
    • Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories
    • McLachlan D.R., Bergeron C., Smith J.E., Boomer D., Rifat S.L. Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology. 46:1996;401-405.
    • (1996) Neurology , vol.46 , pp. 401-405
    • McLachlan, D.R.1    Bergeron, C.2    Smith, J.E.3    Boomer, D.4    Rifat, S.L.5
  • 40
    • 0030921323 scopus 로고    scopus 로고
    • Abnormal expression of the cell cycle regulators p16 and CDK4 in Alzheimer's disease
    • McShea A., Harris P.L.R., Webster K.R., Wahl A.F., Smith M.A. Abnormal expression of the cell cycle regulators p16 and CDK4 in Alzheimer's disease. Am. J. Pathol. 150:1997;1933-1939.
    • (1997) Am. J. Pathol. , vol.150 , pp. 1933-1939
    • McShea, A.1    Harris, P.L.R.2    Webster, K.R.3    Wahl, A.F.4    Smith, M.A.5
  • 41
    • 0025908356 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD): Part II, standardization of the neuropathologic assessment of Alzheimers disease
    • Mirra S.S., Heyman A., McKeel D. et al. The consortium to establish a registry for Alzheimer's disease (CERAD): Part II, standardization of the neuropathologic assessment of Alzheimers disease. Neurology. 41:1991;479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 42
    • 0029892175 scopus 로고    scopus 로고
    • Cerebral amyloid deposition and diffuse plaques in 'normal' aging: Evidence for presymptomatic and very mild Alzheimer's disease
    • Morris J.C., Storandt M., McKeel D.W.J., Rubin E.H., Price J.L., Grant E.A., Berg L. Cerebral amyloid deposition and diffuse plaques in 'normal' aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology. 46:1996;707-719.
    • (1996) Neurology , vol.46 , pp. 707-719
    • Morris, J.C.1    Storandt, M.2    McKeel, D.W.J.3    Rubin, E.H.4    Price, J.L.5    Grant, E.A.6    Berg, L.7
  • 43
    • 0025687381 scopus 로고
    • Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: A comparison with Alzheimer's disease
    • Murphy G.M.J., Eng L.F., Ellis W.G., Perry G., Meissner L.C., Tinklenberg J.R. Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease. Brain Res. 537:1990;102-108.
    • (1990) Brain Res. , vol.537 , pp. 102-108
    • Murphy, G.M.J.1    Eng, L.F.2    Ellis, W.G.3    Perry, G.4    Meissner, L.C.5    Tinklenberg, J.R.6
  • 45
    • 0032562095 scopus 로고    scopus 로고
    • Early glycoxidation damage in brains from Down's syndrome
    • Odetti P., Angelini G., Dapino D. et al. Early glycoxidation damage in brains from Down's syndrome. Biochem. Biophys. Res. Comm. 243:1998;849-851.
    • (1998) Biochem. Biophys. Res. Comm. , vol.243 , pp. 849-851
    • Odetti, P.1    Angelini, G.2    Dapino, D.3
  • 46
    • 0018827099 scopus 로고
    • Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons
    • Perl D.P., Brody A.R. Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons. Science. 208:1980;297-299.
    • (1980) Science , vol.208 , pp. 297-299
    • Perl, D.P.1    Brody, A.R.2
  • 49
    • 0027132358 scopus 로고
    • Senile plaques and neurofibrillary tangles: What role do they play in Alzheimer's disease?
    • Perry G., Smith M.A. Senile plaques and neurofibrillary tangles: what role do they play in Alzheimer's disease? Clin. Neurosci. 1:1993;199-203.
    • (1993) Clin. Neurosci. , vol.1 , pp. 199-203
    • Perry, G.1    Smith, M.A.2
  • 50
    • 0345483592 scopus 로고    scopus 로고
    • The case of vascular abnormalities in Alzheimer disease
    • (in press).
    • Perry, G., Smith, M.A., 1998. The case of vascular abnormalities in Alzheimer disease. Invest. Drugs Res. Alert (in press).
    • (1998) Invest. Drugs Res. Alert
    • Perry, G.1    Smith, M.A.2
  • 51
    • 0029655453 scopus 로고    scopus 로고
    • Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: An index of oxidative stress
    • Praprotnik D., Smith M.A., Richey P.L., Vinters H.V., Perry G. Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress. Acta Neuropathol. 91:1996;1-5.
    • (1996) Acta Neuropathol. , vol.91 , pp. 1-5
    • Praprotnik, D.1    Smith, M.A.2    Richey, P.L.3    Vinters, H.V.4    Perry, G.5
  • 52
    • 0030049915 scopus 로고    scopus 로고
    • Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease
    • Praprotnik D., Smith M.A., Richey P.L., Vinters H.V., Perry G. Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease. Acta Neuropathol. 91:1996;226-235.
    • (1996) Acta Neuropathol. , vol.91 , pp. 226-235
    • Praprotnik, D.1    Smith, M.A.2    Richey, P.L.3    Vinters, H.V.4    Perry, G.5
  • 53
    • 0028951080 scopus 로고
    • Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: Implications for disease pathogenesis
    • Richey P.L., Siedlak S.L., Smith M.A., Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis. Biochem. Biophys. Res. Commun. 208:1995;657-663.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 657-663
    • Richey, P.L.1    Siedlak, S.L.2    Smith, M.A.3    Perry, G.4
  • 54
    • 0029317063 scopus 로고
    • Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease
    • Rifenburg R.P., Perry G. Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease. Neurodegeneration. 4:1995;235-237.
    • (1995) Neurodegeneration , vol.4 , pp. 235-237
    • Rifenburg, R.P.1    Perry, G.2
  • 55
    • 0025840201 scopus 로고
    • BetaA4 amyloid protein deposition in brain after head trauma
    • Roberts G.W., Gentleman S.M., Lynch A., Graham D.I. BetaA4 amyloid protein deposition in brain after head trauma. Lancet. 338:1991;1422-1423.
    • (1991) Lancet , vol.338 , pp. 1422-1423
    • Roberts, G.W.1    Gentleman, S.M.2    Lynch, A.3    Graham, D.I.4
  • 56
    • 0027936838 scopus 로고
    • Apolipoprotein E affects the rate of Alzheimer's disease expression: Β-amyloid burden is a secondary consequence dependent on ApoE genotype and duration of disease
    • Roses A.D. Apolipoprotein E affects the rate of Alzheimer's disease expression: β-amyloid burden is a secondary consequence dependent on ApoE genotype and duration of disease. J. Neuropathol. Exp. Neurol. 53:1994;429-437.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 429-437
    • Roses, A.D.1
  • 57
    • 0013859362 scopus 로고
    • Correlation between scores for dementia and counts of'senile plaques in cerebral grey matter of elderly subjects
    • Roth M., Tomlinson B.E., Blessed G. Correlation between scores for dementia and counts of'senile plaques in cerebral grey matter of elderly subjects. Nature. 209:1966;109-110.
    • (1966) Nature , vol.209 , pp. 109-110
    • Roth, M.1    Tomlinson, B.E.2    Blessed, G.3
  • 58
    • 0014059993 scopus 로고
    • The relationship between quantitative measures of dementia and of degenerative changes in the cerebral grey matter of elderly subjects
    • Roth M., Tomlinson B.E., Blessed G. The relationship between quantitative measures of dementia and of degenerative changes in the cerebral grey matter of elderly subjects. Proc. Royal Soc. Med. 60:1967;254-260.
    • (1967) Proc. Royal Soc. Med. , vol.60 , pp. 254-260
    • Roth, M.1    Tomlinson, B.E.2    Blessed, G.3
  • 59
    • 0028916836 scopus 로고
    • Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging
    • Roth G.S., Joseph J.A., Mason R.P. Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging. Trends Neurosci. 18:1995;203-206.
    • (1995) Trends Neurosci. , vol.18 , pp. 203-206
    • Roth, G.S.1    Joseph, J.A.2    Mason, R.P.3
  • 61
    • 0030983405 scopus 로고    scopus 로고
    • Mechanisms of neurotoxicity associated with amyloid β deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: A critical appraisal
    • Sayre L.M., Zagorski M.G., Surewicz W.K., Krafft G.A., Perry G. Mechanisms of neurotoxicity associated with amyloid β deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal. Chem. Res. Toxicol. 10:1997;518-526.
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 518-526
    • Sayre, L.M.1    Zagorski, M.G.2    Surewicz, W.K.3    Krafft, G.A.4    Perry, G.5
  • 62
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes phenotypes and treatments
    • Selkoe D.J. Alzheimer's disease: genotypes phenotypes and treatments. Science. 275:1997;630-631.
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 63
    • 0025217385 scopus 로고
    • Quantitative assessment of cortical synaptic density in Alzheimer's disease
    • Scheff S.W., DeKosky S.T., Price D.A. Quantitative assessment of cortical synaptic density in Alzheimer's disease. Neurobiol. Aging. 11:1990;29-37.
    • (1990) Neurobiol. Aging , vol.11 , pp. 29-37
    • Scheff, S.W.1    Dekosky, S.T.2    Price, D.A.3
  • 65
    • 0031614624 scopus 로고    scopus 로고
    • Alzheimer disease
    • In: Bradley, R.J., Harris, R.A. (Eds.), Academic Press, San Diego
    • Smith, M.A., 1998. Alzheimer disease. In: Bradley, R.J., Harris, R.A. (Eds.), International Review of Neurobiology, 42. Academic Press, San Diego, pp. 1-54.
    • (1998) International Review of Neurobiology , vol.42 , pp. 1-54
    • Smith, M.A.1
  • 66
    • 0031066614 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimer disease: An alternative to the amyloid hypothesis
    • Smith M. A., Perry G. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J. Neuropathol. Exp. Neurol. 56:1997;217.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 217
    • Smith, M.A.1    Perry, G.2
  • 67
    • 0028942632 scopus 로고
    • Tau protein directly interacts with the amyloid β-protein precursor: Implications for Alzheimer's disease
    • Smith M.A., Siedlak S.L., Richey P.L. et al. Tau protein directly interacts with the amyloid β-protein precursor: Implications for Alzheimer's disease. Nature Med. 1:1995;365-369.
    • (1995) Nature Med. , vol.1 , pp. 365-369
    • Smith, M.A.1    Siedlak, S.L.2    Richey, P.L.3
  • 69
    • 0030071573 scopus 로고    scopus 로고
    • Diabetes mellitus and Alzheimer's disease: Glycation as a biochemical link
    • Smith M.A., Sayre L.M., Perry G. Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link. Diabetologia. 39:1996;247.
    • (1996) Diabetologia , vol.39 , pp. 247
    • Smith, M.A.1    Sayre, L.M.2    Perry, G.3
  • 70
    • 0029878826 scopus 로고    scopus 로고
    • Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease
    • Smith M.A., Siedlak S.L., Richey P.L., Nagaraj R.H., Elhammer A., Perry G. Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease. Brain Res. 717:1996;99-108.
    • (1996) Brain Res. , vol.717 , pp. 99-108
    • Smith, M.A.1    Siedlak, S.L.2    Richey, P.L.3    Nagaraj, R.H.4    Elhammer, A.5    Perry, G.6
  • 72
    • 0002288498 scopus 로고    scopus 로고
    • Diet and oxidative stress: A novel synthesis of epidemiological data on Alzheimer's disease
    • Smith M.A., Petot G.J., Perry G. Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease. Alz. Dis. Rev. 2:1997;58-60.
    • (1997) Alz. Dis. Rev. , vol.2 , pp. 58-60
    • Smith, M.A.1    Petot, G.J.2    Perry, G.3
  • 74
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • Smith M.A., Harris P.L.R., Sayre L.M., Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc. Natl. Acad. Sci. USA. 94:1997;9866-9868.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.R.2    Sayre, L.M.3    Perry, G.4
  • 75
    • 0031981072 scopus 로고    scopus 로고
    • Amyloid-β deposition in Alzheimer transgenic mice initiates oxidative stress
    • Smith M.A., Hirai K., Hsiao K. et al. Amyloid-β deposition in Alzheimer transgenic mice initiates oxidative stress. J. Neurochem. 70:1998;2212-2215.
    • (1998) J. Neurochem. , vol.70 , pp. 2212-2215
    • Smith, M.A.1    Hirai, K.2    Hsiao, K.3
  • 77
    • 0025223441 scopus 로고
    • Early accumulation of heparan sulfate in neurons and in the β-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome
    • Snow A.D., Mar H., Nochlin D., Sekiguchi R.T., Kimata K., Koike Y., Wight T.N. Early accumulation of heparan sulfate in neurons and in the β-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome. Am. J. Pathol. 137:1990;1253-1270.
    • (1990) Am. J. Pathol. , vol.137 , pp. 1253-1270
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Sekiguchi, R.T.4    Kimata, K.5    Koike, Y.6    Wight, T.N.7
  • 80
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
    • Strittmatter W.J., Weisgraber K.H., Huang D.Y. et al. Binding of human apolipoprotein E to synthetic amyloid β peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;8098-8102.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3
  • 81
    • 0014193263 scopus 로고
    • Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia
    • Suzuki K., Terry R.D. Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia. Acta Neuropathol. 8:1967;276-284.
    • (1967) Acta Neuropathol. , vol.8 , pp. 276-284
    • Suzuki, K.1    Terry, R.D.2
  • 82
    • 13344293701 scopus 로고    scopus 로고
    • Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
    • Teller J.K., Russo C., DeBusk L.M. et al. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nature Med. 2:1996;93-95.
    • (1996) Nature Med. , vol.2 , pp. 93-95
    • Teller, J.K.1    Russo, C.2    Debusk, L.M.3
  • 83
    • 0029795197 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimer disease: An alternative to the amyloid hypothesis
    • Terry R.D. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J. Neuropath. Exp. Neurol. 55:1996;1023-1025.
    • (1996) J. Neuropath. Exp. Neurol. , vol.55 , pp. 1023-1025
    • Terry, R.D.1
  • 84
    • 0000748465 scopus 로고
    • Experimental production of neurofibrillary degeneration
    • Terry R.D., Peña C. Experimental production of neurofibrillary degeneration. J. Neuropathol. Exp. Neurol. 24:1965;200-210.
    • (1965) J. Neuropathol. Exp. Neurol. , vol.24 , pp. 200-210
    • Terry, R.D.1    Peña, C.2
  • 85
    • 0014851803 scopus 로고
    • Observations on the brains of demented old people
    • Tomlinson B.E., Blessed G., Roth M. Observations on the brains of demented old people. J. Neurol. Sci. 11:1970;205-242.
    • (1970) J. Neurol. Sci. , vol.11 , pp. 205-242
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 86
    • 0027135874 scopus 로고
    • PHFτ (A68): From pathological marker to potential mediator of neuronal dysfunction and degeneration in Alzheimer's disease
    • Trojanowski J.Q., Schmidt M.L., Shin R.-W., Bramblett G.T., Goedert M., Lee V.M.-Y. PHFτ (A68): from pathological marker to potential mediator of neuronal dysfunction and degeneration in Alzheimer's disease. Clin. Neurosci. 1:1993;184-191.
    • (1993) Clin. Neurosci. , vol.1 , pp. 184-191
    • Trojanowski, J.Q.1    Schmidt, M.L.2    Shin, R.-W.3    Bramblett, G.T.4    Goedert, M.5    Lee, V.M.-Y.6
  • 87
    • 0022637266 scopus 로고
    • Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum
    • Troncoso J.C., Sternberger N.H., Sternberger L.A., Hoffman P.N., Price D.L. Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum. Brain Res. 364:1986;295-300.
    • (1986) Brain Res. , vol.364 , pp. 295-300
    • Troncoso, J.C.1    Sternberger, N.H.2    Sternberger, L.A.3    Hoffman, P.N.4    Price, D.L.5
  • 88
    • 0031960759 scopus 로고    scopus 로고
    • WAF1/CIP1 in neurons following focal cerebral ischemia
    • WAF1/CIP1 in neurons following focal cerebral ischemia. Neuroscience. 84:1998;1097-1112.
    • (1998) Neuroscience , vol.84 , pp. 1097-1112
    • Van Lookeren Campagne, M.1    Gill, R.2
  • 90
    • 0019935804 scopus 로고
    • Plaques, tangles and dementia: A quantitative study
    • Wilcock G.K., Esiri M.M. Plaques, tangles and dementia: a quantitative study. J. Neurol. Sci. 56:1982;343-356.
    • (1982) J. Neurol. Sci. , vol.56 , pp. 343-356
    • Wilcock, G.K.1    Esiri, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.