-
1
-
-
0026432318
-
β-Amyloid and the pathogenesis of Alzheimer's disease
-
Yanker BA, Mesulam M-M: β-Amyloid and the pathogenesis of Alzheimer's disease. N Engl J Med 1991;325:1849-1857.
-
(1991)
N Engl J Med
, vol.325
, pp. 1849-1857
-
-
Yanker, B.A.1
Mesulam, M.-M.2
-
2
-
-
0027062755
-
Epidemiology of Alzheimer's disease
-
Breteler MMB, Claus JJ, van Duijn CM, Launer LJ, Hofman A: Epidemiology of Alzheimer's Disease. Epidemiol Rev 1992;14:59-82.
-
(1992)
Epidemiol Rev
, vol.14
, pp. 59-82
-
-
Breteler, M.M.B.1
Claus, J.J.2
Van Duijn, C.M.3
Launer, L.J.4
Hofman, A.5
-
3
-
-
0027404280
-
A population-based study of dementia in 85-year-olds
-
Skoog I, Nilson L, Palmertz B, Andreasson L-A, Svanborg A: A population-based study of dementia in 85-year-olds. N Engl J Med 1993;328:153-158.
-
(1993)
N Engl J Med
, vol.328
, pp. 153-158
-
-
Skoog, I.1
Nilson, L.2
Palmertz, B.3
Andreasson, L.-A.4
Svanborg, A.5
-
4
-
-
0031057837
-
Exploring the etiology of Alzheimer disease using molecular genetics
-
Lendon C, Ashall F, Goate AM: Exploring the etiology of Alzheimer disease using molecular genetics. JAMA 1997;277:825-831.
-
(1997)
JAMA
, vol.277
, pp. 825-831
-
-
Lendon, C.1
Ashall, F.2
Goate, A.M.3
-
5
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD: Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
6
-
-
0027194791
-
Gene dose of apoliprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel D, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA: Gene dose of apoliprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
7
-
-
0027327267
-
Association of apolipoprotein E allele E4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders AM, Strittmatter WJ, Schmechel D, St George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-Maclachlan DR, Alberts MJ, Hulette C, Grain B, Goldgaber D, Roses AD: Association of apolipoprotein E allele E4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
St George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-Maclachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Grain, B.12
Goldgaber, D.13
Roses, A.D.14
-
8
-
-
0028026997
-
Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease
-
van Duijn CM, de Knijff P, Cruts M, Wehnert A, Havekes LM, Hofman A, van Broeckhoven C: Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease. Nat Genet 1994;7:74-78.
-
(1994)
Nat Genet
, vol.7
, pp. 74-78
-
-
Van Duijn, C.M.1
De Knijff, P.2
Cruts, M.3
Wehnert, A.4
Havekes, L.M.5
Hofman, A.6
Van Broeckhoven, C.7
-
9
-
-
0028171516
-
Apolipoprotein E4 allele and cognitive decline in elderly man
-
Feskens EJM, Havekes LM, Kalmijn S, de Knijff P, Launer LJ, Kromhout D: Apolipoprotein E4 allele and cognitive decline in elderly man. BMJ 1994;309:1202-1206.
-
(1994)
BMJ
, vol.309
, pp. 1202-1206
-
-
Feskens, E.J.M.1
Havekes, L.M.2
Kalmijn, S.3
De Knijff, P.4
Launer, L.J.5
Kromhout, D.6
-
10
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: A meta-analysis
-
Fairer LA, Cupples A, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericek-Vance MA, Risch N, van Duijn CM, for the APOE and Alzheimer's Disease Meta-Analysis Consortium: Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: A meta-analysis. JAMA 1997;278:1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Fairer, L.A.1
Cupples, A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericek-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
11
-
-
12044254746
-
Binding of human apolipoprotein E to synthetic amyloid β-peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter WJ, Weisgraber KH, Huang DY, Dong L-M, Salvesen GS, Pericak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD: Binding of human apolipoprotein E to synthetic amyloid β-peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993;90:8089-8102.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8089-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.-M.4
Salvesen, G.S.5
Pericak-Vance, M.6
Schmechel, D.7
Saunders, A.M.8
Goldgaber, D.9
Roses, A.D.10
-
12
-
-
0027931854
-
Isoform-specific binding of apolipoprotein E to β-amyloid
-
LaDu MJ, Falduto MT, Manelli AM, Reardon CA, Getz GS, Frail DE: Isoform-specific binding of apolipoprotein E to β-amyloid. J Biol Chem 1994;269:23404-23406.
-
(1994)
J Biol Chem
, vol.269
, pp. 23404-23406
-
-
LaDu, M.J.1
Falduto, M.T.2
Manelli, A.M.3
Reardon, C.A.4
Getz, G.S.5
Frail, D.E.6
-
13
-
-
0028269666
-
Hypothesis: Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E geno-type
-
Strittmatter WJ, Weisgraber KH, Goedert M, Saunders AM, Huang D, Corder EH, Dong L-M, Jakes R, Alberts MJ, Gilbert JR, Han S-H, Hulette C, Einstein G, Schmechel DE, Pericak-Vance MA, Roses AD: Hypothesis: Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E geno-type. Exp Neurol 1994;125:163-171.
-
(1994)
Exp Neurol
, vol.125
, pp. 163-171
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Goedert, M.3
Saunders, A.M.4
Huang, D.5
Corder, E.H.6
Dong, L.-M.7
Jakes, R.8
Alberts, M.J.9
Gilbert, J.R.10
Han, S.-H.11
Hulette, C.12
Einstein, G.13
Schmechel, D.E.14
Pericak-Vance, M.A.15
Roses, A.D.16
-
14
-
-
0028232662
-
Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
-
Nathan BP, Bellosta S, Sanan DA, Weisgraber KH, Mahley RW, Pitas RE: Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science 1994;264:850-852.
-
(1994)
Science
, vol.264
, pp. 850-852
-
-
Nathan, B.P.1
Bellosta, S.2
Sanan, D.A.3
Weisgraber, K.H.4
Mahley, R.W.5
Pitas, R.E.6
-
15
-
-
0029765553
-
Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and p-amyloid peptides
-
Miyate M, Smith J: Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and p-amyloid peptides. Nat Genet 1996;14:55-61.
-
(1996)
Nat Genet
, vol.14
, pp. 55-61
-
-
Miyate, M.1
Smith, J.2
-
16
-
-
0028906808
-
Purification of apolipoprotein E attenuates isoform-specific binding to β-amyloid
-
LaDu MJ, Pederson TM, Frail DE, Reardon CA, Getz GS, Falduto MT: Purification of apolipoprotein E attenuates isoform-specific binding to β-amyloid. J Biol Chem 1995;270:9039-9042.
-
(1995)
J Biol Chem
, vol.270
, pp. 9039-9042
-
-
LaDu, M.J.1
Pederson, T.M.2
Frail, D.E.3
Reardon, C.A.4
Getz, G.S.5
Falduto, M.T.6
-
17
-
-
0030614814
-
Apolipoprotein E ε4 and the risk of dementia with stroke
-
Slooter AJC, Tang M-X, van Duijn CM, Stern Y, Ott A, Bell K, Breteler MMB, van Broeckhoven C, Tatemichi TK, Tycko B, Hofman A, Mayeux R: Apolipoprotein E ε4 and the risk of dementia with stroke. JAMA 1997;277:818-821.
-
(1997)
JAMA
, vol.277
, pp. 818-821
-
-
Slooter, A.J.C.1
Tang, M.-X.2
Van Duijn, C.M.3
Stern, Y.4
Ott, A.5
Bell, K.6
Breteler, M.M.B.7
Van Broeckhoven, C.8
Tatemichi, T.K.9
Tycko, B.10
Hofman, A.11
Mayeux, R.12
-
18
-
-
0027987314
-
Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
-
de Knijff P, van den Maagdenberg AMJM, Frants RR, Havekes LM: Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum Mutat 1994;4:178-194.
-
(1994)
Hum Mutat
, vol.4
, pp. 178-194
-
-
De Knijff, P.1
Van Den Maagdenberg, A.M.J.M.2
Frants, R.R.3
Havekes, L.M.4
-
19
-
-
0023885544
-
Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promotor region of the APOC1 gene
-
Smit M, van de Kooij-Meijs E, Woudt LP, Havekes LM, Frants RR: Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promotor region of the APOC1 gene. Biochem Biophys Res Commun 1988;152:1282-1288.
-
(1988)
Biochem Biophys Res Commun
, vol.152
, pp. 1282-1288
-
-
Smit, M.1
Van De Kooij-Meijs, E.2
Woudt, L.P.3
Havekes, L.M.4
Frants, R.R.5
-
20
-
-
0025771286
-
Familial dysbetalipoproteinemia associated with apolipoprotein E3-Leiden in an extended multigeneration pedigree
-
de Knijff P, van den Maagdenberg AMJM, Stalenhoef AFH, Gevers Leuven JA, Demacker PNM, Kuyt LP, Frants RR, Havekes LM: Familial dysbetalipoproteinemia associated with apolipoprotein E3-Leiden in an extended multigeneration pedigree. J Clin Invest 1991;88:643-655.
-
(1991)
J Clin Invest
, vol.88
, pp. 643-655
-
-
De Knijff, P.1
Van Den Maagdenberg, A.M.J.M.2
Stalenhoef, A.F.H.3
Gevers Leuven, J.A.4
Demacker, P.N.M.5
Kuyt, L.P.6
Frants, R.R.7
Havekes, L.M.8
-
21
-
-
0027524456
-
Characterization of five new mutants in the carboxyl-terminal domain of human apolipoprotein E: No coseggragation with severe hyperlipidemia
-
van den Maagdenberg AMJM, Weng W, de Bruijn IH, de Knijff P, Funke H, Smelt AHM, Gevers Leuven JA, van't Hooft FM, Assmann G, Hofker MH, Havekes LM, Frants RR: Characterization of five new mutants in the carboxyl-terminal domain of human apolipoprotein E: No coseggragation with severe hyperlipidemia. Am J Hum Genet 1993;52:937-946.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 937-946
-
-
Van Den Maagdenberg, A.1
Weng, W.2
De Bruijn, I.H.3
De Knijff, P.4
Funke, H.5
Smelt, A.H.M.6
Gevers Leuven, J.A.7
Van't Hooft, F.M.8
Assmann, G.9
Hofker, M.H.10
Havekes, L.M.11
Frants, R.R.12
-
22
-
-
0028040870
-
Variable expression of familial dysbetalipoproteinemia (FD) associated with apolipoprotein E2(Lys1 46→ Gln)
-
de Knijff P, van den Maagdenberg AMJM, Boomsma DI, Stalenhoef AFH, Smelt AHM, Kastelein J, Marais AD, Frants RR, Havekes LM: Variable expression of familial dysbetalipoproteinemia (FD) associated with apolipoprotein E2(Lys1 46→ Gln). J Clin Invest 1994;94:1252-1262.
-
(1994)
J Clin Invest
, vol.94
, pp. 1252-1262
-
-
De Knijff, P.1
Van Den Maagdenberg, A.M.J.M.2
Boomsma, D.I.3
Stalenhoef, A.F.H.4
Smelt, A.H.M.5
Kastelein, J.6
Marais, A.D.7
Frants, R.R.8
Havekes, L.M.9
-
23
-
-
0030054380
-
A newly identified polymorphism in the apolipoprotein E gene enhancer region is associated with AD and strongly with the c4 allele
-
Mui S, Briggs M, Chung H, Wallace RB, Gomez-Isla T, Rebeck GW, Hyman BT: A newly identified polymorphism in the apolipoprotein E gene enhancer region is associated with AD and strongly with the c4 allele. Neurology 1996;47:196-201.
-
(1996)
Neurology
, vol.47
, pp. 196-201
-
-
Mui, S.1
Briggs, M.2
Chung, H.3
Wallace, R.B.4
Gomez-Isla, T.5
Rebeck, G.W.6
Hyman, B.T.7
-
24
-
-
0031911596
-
A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
Lambert J-C, Pasquir F, Cottel D, Frigard B, Maouyel P, Chartier-Harlin M-C: A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease. Hum Mol Genet 1998;7:533-540.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 533-540
-
-
Lambert, J.-C.1
Pasquir, F.2
Cottel, D.3
Frigard, B.4
Maouyel, P.5
Chartier-Harlin, M.-C.6
-
25
-
-
0031278270
-
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
-
Bales KR, Verina T, Dodel RC, Du Y, Altstiel L, Bender M, Hyslop P, Johnstone EM, Little SP, Cummins DJ, Piccardo P, Ghetti B, Paul SM: Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition. Nat Genet 1997;17:263-264.
-
(1997)
Nat Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
Hyslop, P.7
Johnstone, E.M.8
Little, S.P.9
Cummins, D.J.10
Piccardo, P.11
Ghetti, B.12
Paul, S.M.13
-
26
-
-
0028988736
-
Reduced survival of patients with early-onset Alzheimer's disease that carry the apolipoprotein E2 allele
-
van Duijn CM, de Knijff P, Wehnert A, De Voecht J, Bronzova JB, Havekes LM, Hofman A, Van Broeckhoven C: Reduced survival of patients with early-onset Alzheimer's disease that carry the apolipoprotein E2 allele. Ann Neurology 1995;37:605-610.
-
(1995)
Ann Neurology
, vol.37
, pp. 605-610
-
-
Van Duijn, C.M.1
De Knijff, P.2
Wehnert, A.3
De Voecht, J.4
Bronzova, J.B.5
Havekes, L.M.6
Hofman, A.7
Van Broeckhoven, C.8
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