Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 63, Issue , 1998, Pages 301-309

  McCracken, S ^a   Rosonina, E ^a   Fong, N ^b   Sikes, M ^c   Beyer, A ^c   O'Hare, K ^d   Shuman, S ^e   Bentley, D ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; RNA POLYMERASE II; ALPHA AMANITIN; CYCLIN DEPENDENT KINASE 7; CYCLIN H; GUANOSINE TRIPHOSPHATASE; METHYLTRANSFERASE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN VP16; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR GAL4; TRANSCRIPTION FACTOR IIH;

CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; ENZYME STRUCTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA SYNTHESIS; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION; AFFINITY CHROMATOGRAPHY; CONTROLLED STUDY; IMMUNOFLUORESCENCE; NUCLEAR LOCALIZATION SIGNAL; POLYADENYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RIBONUCLEASE PROTECTION ASSAY; RNA CAPPING; RNA PROCESSING; RNA SPLICING; RNA TRANSLATION; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

EID: 0032459207     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1998.63.301     Document Type: Conference Paper

References (61)

1. Akhtar A., Faye G., and Bentley D. 1996. Distinct activated and non-activated RNA polymerase II complexes in yeast. EMBO J. 15: 4654.
2. Allison L.A., Moyle M., Shales M., and Ingles C.J. 1985. Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases. Cell 42: 599.
3. Bartolomei M.S., Halden N.F., Cullen C.R., and Corden J.L. 1988. Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II. Mol Cell. Biol. 8: 330.
4. Bentley D. 1995. Regulation of transcriptional elongation by RNA polymerase II. Curr. Opin. Genet. Dev. 5: 210.
5. Blau J., Xiao H., McCracken S., O'Hare P., Greenblatt J., and Bentley D. 1996. Three functional classes of transcriptional activation domain. Mol. Cell. Biol. 16: 2044.
6. Bregman D.B., Du L., van der Zee S., and Warren S.L. 1995. Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains. J. Cell Biol. 129: 287.
7. Chiou H.C., Dabrowski C., and Alwine J.C. 1991. Simian virus 40 late mRNA leader sequences involved in augmenting mRNA accumulation via multiple mechanisms, including increased polyadenylation efficiency. J. Virol. 65: 6677.
8. Chun R.F. and Jeang K.T. 1996. Requirements for RNA polymerase II carboxyl-terminal domain for activated transcription of human retroviruses human T-cell lymphotropic virus I and HIV 1. J. Biol. Chem. 271: 27888.
9. Connelly S. and Manley J.L. 1988. A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes Dev. 2: 440.
10. Cooke C. and Alwine J.C. 1996. The cap and the 3′ splice site similarly affect polyadenylation efficiency. Mol. Cell. Biol. 16: 2579.
11. Coppola J.A., Field A.S., and Luse D.S. 1983. Promoter-proximal pausing by RNA polymerase II in vitro: Transcripts shorter than 20 nucleotides are not capped. Proc. Natl. Acad. Sci. 80: 1251.
12. Corden J.L. and Ingles C.J. 1992. Carboxy-terminal domain of the largest subunit of eukaryotic RNA polymerase II. In Transcriptional regulation (ed. S.L. McKnight and K.R. Yamamoto), p. 81. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
13. Corden J.L., Cadena D.L., Ahearn J.M., Jr., and Dahmus M.E. 1985. A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. Proc. Natl. Acad. Sci. 82: 7934.
14. Dahmus M.E. 1996. Reversible phosphorylation of the C-terminal domain of RNA polymerase II. J. Biol. Chem.271: 19009.
15. Du L. and Warren S.L. 1997. Functional interaction between the carboxy-terminal domain of RNA and pre-mRNA splicing. J. Cell Biol. 136: 5.
16. Edery I., Chu L.L., Sonenberg N., and Pelletier J. 1995. An efficient strategy to isolate full-length cDNAs based on an mRNA cap retention procedure (CAPture). Mol. Cell. Biol. 15: 3363.
17. Garcia-Martinez L.F., Mavankal G., Neveu J.M., Lane W.S., Ivanov D., and Gaynor R.B. 1997. Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. EMBO J. 16: 2836.
18. Gerber H.P., Hagmann M., Seipel K., Georgiev O., West M.A., Litingtung Y., Schaffner W., and Corden J.L. 1995. RNA polymerase II C-terminal domain required for enhancer-driven transcription. Nature 374: 660.
19. Hirose Y. and Manley J.L. 1998. RNA polymerase II is an essential mRNA polyadenylation factor. Nature 395: 93.
20. Ho C.K., Sriskanda V., McCracken S., Bentley D., Schwer B., and Shuman S. 1998. The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II. J. Biol. Chem. 273: 9577.
21. Itoh N., Yamada H., Kaziro Y., and Mizumoto K. 1987. Messenger RNA guanylyltransferase from Saccharomyces cere-visiae. Large scale purification, subunit functions, and subcellular localization. J. Biol. Chem. 262: 1989.
22. Izaurralde E., Lewis J., McGuigan C., Jankowska M., Darzynkiewicz E., and Mattaj I.W. 1994. A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell 78: 657.
23. Kao S.Y., Calman A.F., Luciw P.A., and Peterlin B.M. 1987. Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330: 489.
24. Krumm A., Hickey L., and Groudine M. 1995. Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation. Genes Dev. 9: 559.
25. Krumm A., Meulia T., and Groudine M. 1993. Common mechanisms for the control of eukaryotic transcriptional elongation. BioEssays 15: 659.
26. Logan J., Falck-Pedersen E., Darnell J.E., Jr., and Shenk T. 1987. A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc. Natl. Acad. Sci. 84: 8306.
27. Mancebo H.S.Y., Lee G., Flygare J., Tomassini J., Luu P., Zhu Y.R., Peno J.M., Blau C., Hazuda D., Price D., and Flores O. 1997. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev. 11: 2633.
28. Mao X., Schwer B., and Shuman S. 1995. Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene. Mol. Cell. Biol. 15: 4167.
29. Marciniak R.A. and Sharp P.A. 1991. HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J. 10:4189.
30. Marshall N.F. and Price D.H. 1992. Control of formation of two distinct classes of RNA polymerase II elongation complexes. Mol. Cell. Biol. 12: 2078.
31. Marshall N.F., Peng J.M., Xie Z., and Price D.H. 1996. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271: 27176.
32. McCracken S., Fong N., Yankulov K., Ballantyne S., Pan G.H., Greenblatt J., Patterson S.D., Wickens M., and Bentley D.L. 1997a. The C-terminal domain of RNA polymerase II couples messenger RNA processing to transcription. Nature 385:357.
33. McCracken S., Fong N., Rosonina E., Yankulov K., Brothers G., Siderovski D., Hessel A., Foster S., Shuman S., and Bentley D. 1997b. 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. Genes Dev. 11: 3306.
34. McNeil J.B., Agah H., and Bentley D. 1998. Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev. 12: 2510.
35. Niwa M. and Berget S.M. 1991. Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes Dev. 5: 2086.
36. Niwa M., Rose S.D., and Berget S.M. 1990. In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev. 4: 1552.
37. Nonet M., Sweetser D., and Young R.A. 1987. Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell 50: 909.
38. O'Brien T., Hardin S., Greenleaf A., and Lis J.T. 1994. Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature 370: 75.
39. Okamoto H., Sheline C.T., Corden J.L., Jones K.A., and Peterlin B.M. 1996. Trans-activation by human immunodeficiency virus tat protein requires the C-terminal domain of RNA polymerase II. Proc. Natl. Acad. Sci. 93: 11575.
40. Pan G., Aso T., and Greenblatt J. 1997. Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators. J. Biol. Chem. 272: 24563.
41. Parada C.A. and Roeder R.G. 1996. Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature 384: 375.
42. Patturajan M., Schulte R.J., Sefton B.M., Berezney R., Vincent M., Bensaude O., Warren S.L., and Corden J.L. 1998. Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Chem. 273: 4689.
43. Rasmussen E.B. and Lis J.T. 1993. In-vivo transcriptional pausing and cap formation on 3 Drosophila heat-shock genes. Proc. Natl. Acad. Sci. 90: 7923.
44. Roy R., Adamczewski J.P., Seroz T., Vermeulen W., Tassan J.P., Schaeffer L., Nigg E.A., Hoeijmakers J., and Egly J.M. 1994. The MO15 cell-cycle kinase is associated with the TFIIH transcription DNA-repair factor. Cell 79: 1093.
45. Sandig V., Lieber A., Bahring S., and Strauss M. 1993. A phage T7 class-III promoter functions as a polymerase II promoter in mammalian cells. Gene 131: 255.
46. Scafe C., Chao D., Lopes J., Hirsch J.P., Henry S., and Young R.A. 1990. RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals. Nature 347:491.
47. Schwer B. and Shuman S. 1994. Mutational analysis of yeast mRNA capping enzyme. Proc. Natl. Acad. Sci. 91: 4328.
48. _. 1996. Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo. RNA 2: 574.
49. Shuman S. 1995. Capping enzyme in eukaryotic mRNA synthesis. Prog. Nucleic Acid Res. Mol. Biol. 50: 101.
50. Simonelig M., Elliott K., Mitchelson A., and O'Hare K. 1996. Interallelic complementation at the suppressor of forked locus of Drosophila reveals complementation between suppressor of forked proteins mutated in different regions. Genetics 142: 1225.
51. Wada T., Takagi T., Yamaguchi Y., Ferdous A., Imai T., Hirose S., Sugimoto S., Yano K., Hartzog G.A., Winston F., Buratowski S:, and Handa H. 1998. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev. 12: 343.
52. Walker S., Greaves R., and O'Hare P. 1993. Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding. Mol. Cell. Biol.; 13: 5233.
53. Wang S.P. and Shuman S. 1997. Structure-function analysis of the mRNA cap methyltransferase of Saccharomyces cerevisiae. J.Biol. Chem. 272: 14683.
54. Wei P., Garber M.E., Fang S.M., Fischer W.H., and Jones K.A. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92: 451.
55. Whitelaw E. and Proudfoot N. 1986. Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3′ end processing in the human alpha 2 globin gene. EMBO J. 5: 2915.
56. Xiao H., Pearson A., Coulombe B., Truant R., Zhang S., Regier J.L., Triezenberg S.J., Reinberg D., Flores O., Ingles C.J., and Greenblatt J. 1994. Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol. Cell. Biol. 14: 7013.
57. Yang X.Z., Herrmann C.H., and Rice A.P. 1996. The human immunodeficiency virus tat proteins specifically associate with tak in vivo and require the carboxy-terminal domain of RNA polymerase II for function. J. Virol. 70: 4576.
58. Yankulov K., Blau J., Purton T., Roberts S., and Bentley D. 1994. Transcriptional elongation by RNA polymerase II is stimulated by transactivators. Cell 77: 749.
59. Yankulov K.Y., Pandes M., McCracken S., Bouchard D., and Bentley D.L. 1996. TFIIH functions in regulating transcriptional elongation by RNA-polymerase II in Xenopus oocytes. Mol. Cell. Biol. 16:3291.
60. Yuryev A., Patturajan M., Litingtung Y., Joshi R., Gentile C., Gebara M., and Corden J. 1996. The CTD of RNA polymerase II interacts with a novel set of SR-like proteins. Proc. Natl. Acad. Sci. 93: 6975.
61. Zhu Y.R., Peery T., Peng T.M., Ramanathan Y., Marshall N., Marshall T., Amendt B., Mathews M.B., and Price D.H. 1997. Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro. Genes Dev. 11: 2622.