Uptake and intracellular trafficking of asialoglycoprotein-polylysine-DNA complexes in isolated rat hepatocytes

Gene Therapy

Volumn 3, Issue 10, 1996, Pages 937-940

  Edwards, R J ^a   Carpenter, D S ^a   Minchin, R F ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Asialoglycoprotein; Gene delivery; Intracellular trafficking; Receptor mediated

Indexed keywords

ASIALOGLYCOPROTEIN; DNA; IODINE 125; POLYLYSINE;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; COMPLEX FORMATION; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; INTERNALIZATION; INTRACELLULAR TRANSPORT; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT;

ANIMALS; ASIALOGLYCOPROTEINS; CELLS, CULTURED; DNA; LIVER; POLYLYSINE; RATS;

ANIMALIA;

EID: 0029860513     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Machy P, Barbet J, Leserman LD. Differential endocytosis of T and B lymphocyte surface molecules evaluated with antibody-bearing fluorescent liposomes containing methotrexate. Proc Natl Acad Sci USA 1982; 79: 4148-4152.
2. Poznansky MJ, Juliano RL. Biological approaches to the controlled delivery of drugs: a critical review. Pharmacol Rev 1984; 36: 277-336.
3. Wu GY, Wu CW. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J Biol Chem 1987; 262: 4429-4432.
4. Wagner E et al. Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci USA 1990; 87: 3410-3414
5. Maxwell IH et al. Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. Cancer Biother 1994; 9: 131-141.
6. Chen J, Gamou S, Takayanagi A, Shimizu N. A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett 1994; 338: 167-169.
7. Thurnher M et al. Carbohydrate receptor-mediated gene transfer to human T leukemic cells. Glycobiology 1994; 4: 429-435.
8. Chen J, Stickles RJ, Daichendt KA. Galactosylated histone-mediated gene transfer and expression. Hum Gene Ther 1994; 5: 429-435.
9. Rojanasakul Y et al. Targeted gene delivery to alveolar macrophages via Fc receptor-mediated endocytosis. Pharm Res 1994; 11: 1731-1736.
10. Remy JS et al. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage towards artificial viruses. Proc Natl Acad Sci USA 1995; 92: 1744-1748.
11. Curiel DT. Receptor-mediated gene delivery employing adenovirus-polylysine-DNA complexes. In: Wolff JA (ed). Gene Therapeutics. Birkhauser: Boston, 1994, pp 99-117.
12. Ledley TS, Ledley FD. Multicompartment, numerical model of cellular events m the pharmacokinetics of gene therapies. Hum Gene Ther 1994; 5: 679-691.
13. Perales JC, Ferkol T, Molas M, Hanson RW. An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes. Eur J Biochem 1994; 226: 255-266.
14. Wagner E et al. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: towards a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 1992; 89: 7934-7938.
15. Wu GY, Wu CH. Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro. Biochemistry 1987; 27: 887-892.
16. Wu GY, Wu CH. Receptor-mediated gene delivery and expression in vivo. J Biol Chem 1988; 263: 14621-14624.
17. Wu GY et al. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J Biol Chem 1991; 266: 14338-14342.
18. Oka JA, Weigel PH. Recycling of the asialoglycoprotein receptor in isolated rat hepatocytes. J Biol Chem 1983; 258: 10253-10262.
19. Chowdhury NR et al. Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis m vivo. J Biol Chem 1993; 268: 11265-11271.
20. Berry MN, Friend DS. High yield preparation of isolated rat liver parenchymal cells. J Biol Chem 1969; 43: 506-520.
21. Seymour CA, Peters TJ. Enzyme activities in human biopsies: assay methods and activities of some lysosomal and membrane enzymes in control tissue and serum. Clin Sci Mol Med 1977; 52: 229-239.
22. MacGregor GR et al. Use of E coli lacZ as a reporter gene. In: Murray EJ (ed). Methods in Molecular Biology. Vol 7. Gene Transfer and Expression Protocols. Humana Press: Clifton, NJ, 1991, pp 217-235.