Structure-based drug design approaches for predicting binding affinities of HIV1 protease inhibitors

Journal of Enzyme Inhibition

Volumn 14, Issue 1, 1998, Pages 1-14

  Reddy, M Rami ^a   Erion, Mark D ^a  

^a Metabasis Therapeutics Inc   (United States)

Author keywords

Free energy perturbation calculation; HIV1 protease; Hydrophobicity; Minimization calculations; Molecular dynamics simulations; Regression methods

Indexed keywords

JG 365; JG 365A; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; BINDING AFFINITY; COMPUTER ANALYSIS; DRUG DESIGN; DRUG STRUCTURE; ENZYME BINDING; METHODOLOGY; PRIORITY JOURNAL; REGRESSION ANALYSIS; REVIEW;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032440681     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.3109/14756369809036542     Document Type: Review

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