An approach to rapid estimation of relative binding affinities of enzyme inhibitors: Application to peptidomimetic inhibitors of the human immunodeficiency virus type 1 protease

Journal of Medicinal Chemistry

Volumn 39, Issue 3, 1996, Pages 705-712

  Viswanadhan, Vellarkad N ^a,d   Rami Reddy, M ^b,d   Wlodawer, Alexander ^c   Varney, Michael D ^b   Weinstein, John N ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b AGOURON PHARMACEUTICALS INC   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Gensia Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; VIRUS ENZYME;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BINDING AFFINITY; CALCULATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENERGY METABOLISM; ENZYME BINDING; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; PREDICTION; THERMODYNAMICS;

EID: 13344282748     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm940778t     Document Type: Article

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