Antiemetic effects of sendide, a peptide tachykinin NK1 receptor antagonist, in the ferret

European Journal of Pharmacology

Volumn 363, Issue 1, 1998, Pages 49-55

  Minami, Masaru ^a   Endo, Toru ^a   Kikuchi, Kazuhiko ^a   Ihira, Emi ^a   Hirafuji, Masahiko ^a   Hamaue, Naoya ^a   Monma, Yoshio ^a   Sakurada, Tsukasa ^b   Tan No, Kohichi ^c   Kisara, Kensuke ^c  

^a KANAZAWA UNIVERSITY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Abdominal afferent vagus nerve activity; Antiemetic activity; Cisplatin; Sendide; Tachykinin NK1 receptor antagonist

Indexed keywords

ANTIEMETIC AGENT; CISPLATIN; GRANISETRON; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SENDIDE; SEROTONIN; SUBSTANCE P; TACHYKININ; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIEMETIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; FERRET; NAUSEA; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; VAGUS NERVE; VOMITING;

ANIMALS; ANTIEMETICS; CISPLATIN; FERRETS; ILEUM; MALE; PEPTIDE FRAGMENTS; PYRROLIDONECARBOXYLIC ACID; RECEPTORS, TACHYKININ; SEROTONIN; SUBSTANCE P; VAGUS NERVE;

EID: 0032431306     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00784-5     Document Type: Article

References (56)

1. Andrews P.L.R. Physiology of nausea and vomiting. Br. J. Anaesth. 69:1992;2s-19s.
2. 3 receptor antagonists and anti-emesis. In: King, F.D., Jones, B.J., Sanger, G.J. (Eds.), 5-Hydroxytryptamine-3 receptor antagonist. CRC Press, Boca Raton, USA, pp. 255-317.
3. Andrews P.L.R., Bhandari P. Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferrets. Neuropharmacology. 32:1993;799-806.
4. Andrews P.L.R., Hawthorn J. The neurophysiology of vomiting. Clin. Gastroenterol. 2:1988;141-168.
5. Andrews P.L.R., Rapeport W.G., Sanger G.J. Neuropharmacology of emesis induced by anti-cancer therapy. Trends in Pharmacol. Sci. 9:1988;334-341.
6. Andrews P.L.R., Davis C.J., Bingham S., Davidson H.I.M., Hawthorn J., Maskell L. The abdominal visceral innervation and the emetic reflex: pathways, pharmacology and plasticity. Can. J. Physiol. Pharmacol. 68:1990;325-345.
7. Baxendale B.R., Vater M., Laver K.M. Dexamethasone reduces pain and swelling following extraction of third molar teeth. Anaesthesia. 48:1993;961-964.
8. Bountra C., Bunce K., Dale T., Gardner C., Jordan C., Twissell D., Ward P. Anti-emetic profile of a non-peptide neurokinin-NK(1) receptor antagonist, CP-99,994, in ferrets. Eur. J. Pharmacol. 249:1993;R3-R4.
9. Costall B., Domeney A.M., Naylor R.J., Tattersall F.D. 5-Hydroxytryptamine M-receptor antagonism to prevent cisplatin-induced emesis. Neuropharmacology. 25:1986;959-961.
10. Dashwood M.R., Muddle J.R., Spyer K.M. Opiate receptor subtypes in the nucleus tractus solitarii of the cat: the effect of vagal section. Eur. J. Pharmacol. 155:1988;85-92.
11. Davidson J.S., Olan L., Boissonade F. The effects of centrally injected NK-1 receptor antagonists on emesis in the ferret. Gastroenterology. 108:1995;A589.
12. 1 receptor antagonist blocks angiotensin II responses in renin transgenic rat medulla oblongata. Hypertension. 31(1 pt 2):1998;473-479.
13. Emanueli C., Grady E.F., Madeddu P., Figini M., Bunnett N.W., Parisi D., Regoli D. Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. Hypertension. 31(6):1998;1299-1304.
14. Endo T., Minami M., Monma Y., Yoshioka M., Saito H., Kinami J., Tosimitsu Y., Parvez H. Effect of GR38032F on cisplatin- and cyclophosphamide-induced emesis in the ferret. Biogenic Amines. 7:1990;525-533.
15. 3 antagonist, on copper sulfate-induced emesis in the ferret. Biogenic Amines. 8:1990;79-86.
16. 3 antagonist) inhibited the increase of serotonin concentration induced by cytotoxic drugs in the area postrema of ferrets. Biogenic Amines. 9:1992;163-175.
17. Endo T., Takahashi M., Minami M., Monma Y., Yoshioka M., Saito H., Parves H. Effects of anticancer drugs on enzyme activities and serotonin release from ileal tissue in ferrets. Biogenic Amines. 9:1993;479-489.
18. Endo T., Nemoto M., Minami M., Yoshioka M., Saito H., Parves H. Changes in the afferent abdominal vagal nerve activity induced by cisplatin and copper sulfate in the ferret. Biogenic Amines. 11:1995;399-407.
19. 1 antagonist, on ileal 5-HT release and afferent abdominal vagal nerve activity in ferrets. Naunyn-Schmiedeberg's Arch. Pharmacol. 358(Suppl. 1):1998;R362. (Abstract).
20. Esseboom E.U., Rojer R.A., Borm J.J.J., Statius van Eps L.W. Prophylaxis of delayed nausea and vomiting after cancer chemotherapy. Neth. J. Med. 47:1995;12-17.
21. Folkers K., Håkanson R., Höring J., Jie-Cheng X., Leander S. Biological evaluation of substance P antagonists. Br. J. Pharmacol. 83:1984;449-456.
22. Helke C.J., Neil J.J., Massari V.L., Loewy A.D. Substance P neurons project from the ventral medulla to the intermediolateral cell column and ventral horn in the rat. Brain Res. 243:1982;147-152.
23. Holmgren S., Grove D.J., Nilsson S. Substance P acts by releasing 5-hydroxytryptamine from enteric neurons in the stomach of the rainbow trout, Salmo gairdneri. Neuroscience. 14:1985;683-693.
24. Ichinose M., Miura M., Yamauchi H., Kageyama N., Tomaki M., Ohuchi Y., Hida W., Miki H., Tamura G., Shirato K. A neurokinin 1-receptor antagonist improves exercise airway narrowing in asthmatic patients. Am. J. Respir. Crit. Care Med. 153:1996;936-941.
25. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
26. 1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats. Eur. J. Pharmacol. 322:1997;165-171.
27. McLean P.G., Garcia-Villar R., Fioramonti J., Bueno L. Effects of tachykinin receptor antagonists on the rat jejunal distension pain response. Eur. J. Pharmacol. 345:1998;247-252.
28. Milano S., Simon C., Grelot L. In vitro release and tissue levels of ileal serotonin after cisplatin-induced emesis in the cat. Clin. Autonom. Res. 1:1991;275-280.
29. Minami, M., Sano, M., Togashi, H., Sakurai, H., Saito, H., 1988. Stroke-related plasma noradrenaline, angiotensin II, arginine-vasopressin and serotonin concentrations in stroke-prone spontaneously hypertensive rats. In: Saito, H., Parvez, H.S., Nagatsu, T. (Eds.), Progress in Hypertension Vol. 1. VSP, Utrecht, The Netherlands, pp. 89-114.
30. Minami M., Hirafuji M., Driscoll E.M., Lucchesi B.R. BMY21190, a potent inhibitor of cAMP phosphodiesterase. Cardiovasc. Drug Rev. 12:1994;173-192.
31. Minami, M., Endo, T., Nemoto, M., Hamaue, N., Hirafuji, M., Monma, Y., Yajima, T., Yoshioka, M., Saito, H., 1995a. How do toxic emetic stimuli cause serotonin release in the gut and the brain? In: Reynolds, D.J.M., Andrews, P.L.R., Davis, C.J. (Eds.), Serotonin and the Scientific Basis of antiemetic therapy. Oxford Clinical Communications, Oxford, pp. 68-76.
32. 4 receptors affects the release of 5-hydroxytryptamine from the ferret and rat intestine. Res. Comm. Mol. Pathol. Pharmacol. 89:1995;131-142.
33. 4 receptor antagonist, in ferrets. Eur. J. Pharmacol. 321:1997;333-342.
34. Miner W.D., Sanger G.J. Inhibition of cisplatin-induced vomiting by selective 5-hydroxytryptamine M-receptor antagonism. Br. J. Pharmacol. 88:1986;497-499.
35. Nilsson S., Holmgren S. Novel neurotransmitters in the autonomic nervous systems of nonmammalian vertebrates. Pharmacol. Ther. 41:1989;257-287.
36. Otsuka M., Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73:1993;229-308.
37. Pernow B. Substance P. Pharmacol. Rev. 35:1983;85-141.
38. Racké K., Schwörer H. Regulation of serotonin release from the intestinal mucosa. Pharmacol. Res. 23:1991;13-25.
39. Racké K., Schwörer H., Kilbinger H. Adrenergic modulation of the release of 5-hydroxytryptamine from the vascularly perfused ileum of guinea-pig. Br. J. Pharmacol. 95:1988;923-931.
40. 4-receptors in guinea pig ileum. Br. J. Pharmacol. 111:1994;419-424.
41. Randich A., Gebhart G.F. Vagal afferent modulation of nociception. Brain Res. Rev. 17:1992;77-99.
42. Sakurada T., Manome Y., Tan-no K., Sakurada S., Kisara K., Ohba M., Terenius L. A selective and extremely potent antagonist of the neurokinin-1 receptor. Brain Res. 593:1992;319-322.
43. 1-receptor antagonist, and morphine in the capsaicin test. Brain Res. 649:1994;319-322.
44. Sakurada T., Katsumata K., Manome Y., Tan-no K., Sakurada S., Kisara K., Ohba M. Antinociceptive effects in the formalin and capsaicin tests after intrathecal administration of substance P analogues in mice. Eur. J. Pharmacol. 242:1993;47-52.
45. Sakurada T., Manome Y., Katsumata K., Tan-no K., Sakurada S., Ohba M., Kisara K. Comparison of antagonistic effects of sendide and CP-96,345 on a spinally mediated behavioral response in mice. Eur. J. Pharmacol. 261:1994;85-96.
46. 3 receptors. Academic Press, London, pp. 207-255.
47. Schwörer H., Racké K., Kilbinger H. Cholinergic modulation of the release of 5-hydroxytryptamine from the guinea pig ileum. Naunyn-Schmiedeberg's Arch. Pharmacol. 336:1987;127-132.
48. 3-receptor antagonist, GR38032F. Cancer Treat. Rev. 14:1987;333-336.
49. 1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret. Eur. J. Pharmacol. 250:1993;R5-R6.
50. Thorndyke M., Holmgren S. Bombesin potentiates the effect of acetylcholine on isolated strips of fish stomach. Regul. Pept. 30:1990;125-135.
51. Togashi H., Yoshioka M., Minami M., Saito H., Kitada C., Fujino M. Substance P and its antagonists: effects on adrenal nerve activity and blood pressure in normotensive and spontaneously hypertensive rats. J. Hypertens. 4(Suppl 3):1986;S217-S219.
52. Wallenstein S.C., Zucker L., Freiss J.L. Some statistical methods useful in circulation research. Cir. Res. 47:1980;1-9.
53. Wang S.C., Borison H.L. A new concept of organization of the central emetic mechanism: Recent studies on the sites of action of apomorphine, copper sulfate and cardiac glycosides. Gastroenterology. 22:1952;1-12.
54. Watson, J.W., Nagahisa, A., Lucot, J.B., Andrews, P.L.R., 1995a. The tachykinins and emesis: towards complete control? In: Reynolds, D.J.M., Andrews, P.L.R., Davis, C.J. (Eds.), Serotonin and the Scientific Basis of antiemetic therapy. Oxford Clinical Communications, Oxford, pp. 233-238.
55. 1 receptor in emetic responses: the anti-emetic effects of CP-99,994 in the ferret and the dog. Br. J. Pharmacol. 115:1995;84-94.
56. Yoshioka M., Ikeda M., Abe H., Togashi H., Minami M., Saito H. Pharmacological characterization of 5-hydroxytryptamine-induced excitation of afferent cervical vagus nerve in anesthetized rats. Br. J. Pharmacol. 106:1992;544-549.