Antiemetic effects of N-3389, a newly synthesized 5-HT3 and 5-HT4 receptor antagonist, in ferrets

European Journal of Pharmacology

Volumn 321, Issue 3, 1997, Pages 333-342

  Minami, Masaru ^a   Endo, Toru ^a   Tamakai, Hiroyuki ^a   Ogawa, Takashi ^a   Hamaue, Naoya ^a   Hirafuji, Masahiko ^a   Monma, Yoshio ^a   Yoshioka, Mitsuhiro ^b   Hagihara, Koichiro ^c  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c NISSHIN SEIFUN GROUP INC   (Japan)

Author keywords

5 HT3 receptor antagonist; 5 HT4 receptor antagonist; Abdominal afferent vagus nerve activity; Antiemetic effect; Ferret; N 3389

Indexed keywords

CISPLATIN; COPPER SULFATE; CYCLOPHOSPHAMIDE; INDISETRON; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIEMETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FERRET; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NERVE CONDUCTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; VAGUS NERVE;

5-METHOXYTRYPTAMINE; ANIMALS; ANTIEMETICS; ANTINEOPLASTIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CISPLATIN; COPPER SULFATE; CYCLOPHOSPHAMIDE; EMETICS; FERRETS; INDAZOLES; MALE; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN; SEROTONIN ANTAGONISTS; VAGUS NERVE; VOMITING;

EID: 0031050181     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00974-0     Document Type: Article

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