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Volumn 5, Issue 4, 1998, Pages 281-299

Serum proteins as drug carriers of anticancer agents: A review

Author keywords

Anticancer Chemotherapy; Drug Delivery Systems; Low Density Lipoprotein; Protein Conjugates; Serum Albumin; Transferrin; Tumor Targeting

Indexed keywords

ABRIN; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CHLORMETHINE; CISPLATIN; CRM 103; CRM 107; CYTOTOXIC AGENT; DAUNORUBICIN; DIPHTHERIA TOXIN; DOXORUBICIN; DRUG CARRIER; FLOXURIDINE; GELONIN; HIGH DENSITY LIPOPROTEIN; HUMAN SERUM ALBUMIN; LOW DENSITY LIPOPROTEIN; METHOTREXATE; MITOMYCIN C; OVOMUCOID; PACLITAXEL; PLASMA PROTEIN; RIBONUCLEASE A; RICIN A; RUTHENIUM COMPLEX; TRANSFERRIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERY LOW DENSITY LIPOPROTEIN; VINCRISTINE; ZINOSTATIN;

EID: 0032421248     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.3109/10717549809065759     Document Type: Review
Times cited : (136)

References (164)
  • 1
    • 0029589645 scopus 로고    scopus 로고
    • Significance of apolipoproteins for structure, function, and classification of plasma lipoproteins
    • Alaupovic, P. 1996. Significance of apolipoproteins for structure, function, and classification of plasma lipoproteins. Methods Enzymol. 263:32-60.
    • (1996) Methods Enzymol. , vol.263 , pp. 32-60
    • Alaupovic, P.1
  • 2
    • 0023659741 scopus 로고
    • Large unilamellar liposomes with low uptake into the reticuloendothelial
    • Allen, T. M., and Chonn, A. 1987. Large unilamellar liposomes with low uptake into the reticuloendothelial. FEBS Lett. 223:42-46.
    • (1987) FEBS Lett. , vol.223 , pp. 42-46
    • Allen, T.M.1    Chonn, A.2
  • 3
    • 0019508117 scopus 로고
    • Inefficient internalization of receptor-bound low density lipoprotein in human carcinoma A-431 cells
    • Anderson, R. G. W., Brown, M. S., and Goldstein, J. L. 1981. Inefficient internalization of receptor-bound low density lipoprotein in human carcinoma A-431 cells. J. Cell Biol. 88:441-452.
    • (1981) J. Cell Biol. , vol.88 , pp. 441-452
    • Anderson, R.G.W.1    Brown, M.S.2    Goldstein, J.L.3
  • 4
    • 0026092328 scopus 로고
    • Identification of tumor sites for increased albumin degradation in sarcoma-bearing mice
    • Andersson, C., Iresjo, B. M., and Lundholm, K. 1991. Identification of tumor sites for increased albumin degradation in sarcoma-bearing mice. J. Surg. Res. 50:156-162.
    • (1991) J. Surg. Res. , vol.50 , pp. 156-162
    • Andersson, C.1    Iresjo, B.M.2    Lundholm, K.3
  • 6
    • 0001363919 scopus 로고
    • Protein transfer in tumor-bearing rats
    • Babson, A. L., and Winnick, T. 1954. Protein transfer in tumor-bearing rats. Cancer Res. 14:606-611.
    • (1954) Cancer Res. , vol.14 , pp. 606-611
    • Babson, A.L.1    Winnick, T.2
  • 8
    • 0026794026 scopus 로고
    • Transferrin conjugates of adriamycin are cytotoxic without intercalating nuclear DNA
    • Barabas, K., Sizensky, J. A., and Faulk, W. P. 1992. Transferrin conjugates of adriamycin are cytotoxic without intercalating nuclear DNA. J. Biol. Chem. 267:9437-9442.
    • (1992) J. Biol. Chem. , vol.267 , pp. 9437-9442
    • Barabas, K.1    Sizensky, J.A.2    Faulk, W.P.3
  • 9
    • 0026328692 scopus 로고
    • Cytotoxicity of transferrin-daunorubicin conjugates
    • Bejaoui, N., Page, M., and Noel, C. 1991. Cytotoxicity of transferrin-daunorubicin conjugates. Anticancer Res. 11:2211-2213.
    • (1991) Anticancer Res. , vol.11 , pp. 2211-2213
    • Bejaoui, N.1    Page, M.2    Noel, C.3
  • 10
    • 0023942583 scopus 로고
    • Killing of K562 cells with conjugates between human transferrin and a ribosome-inactivating protein (SO-6)
    • Bergamaschi, G., Cazzola, M., Dezza, L., Savino, E., Consonni, E., and Lappi, D. 1988. Killing of K562 cells with conjugates between human transferrin and a ribosome-inactivating protein (SO-6). Br. J. Haematol. 68:379-384.
    • (1988) Br. J. Haematol. , vol.68 , pp. 379-384
    • Bergamaschi, G.1    Cazzola, M.2    Dezza, L.3    Savino, E.4    Consonni, E.5    Lappi, D.6
  • 12
    • 0023777840 scopus 로고
    • The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. IV. Therapy of murine melanona B16 by human serum albumin-methotrexate
    • Bostik, J., Bures, L., Spundova, M., and Rehak, L. 1988. The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. IV. Therapy of murine melanona B16 by human serum albumin-methotrexate. Neoplasma 35:343-349.
    • (1988) Neoplasma , vol.35 , pp. 343-349
    • Bostik, J.1    Bures, L.2    Spundova, M.3    Rehak, L.4
  • 14
    • 0023727281 scopus 로고
    • The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. III. Human serum albumin-methotrexate derivative, its preparation and basic testing
    • Bures, L., Bostik, J., Motycka, K., Spundova, M., and Rehak, L. 1988. The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. III. Human serum albumin-methotrexate derivative, its preparation and basic testing. Neoplasma 35:329-342.
    • (1988) Neoplasma , vol.35 , pp. 329-342
    • Bures, L.1    Bostik, J.2    Motycka, K.3    Spundova, M.4    Rehak, L.5
  • 15
    • 0025003675 scopus 로고
    • The use of protein as a carrier of methotrexate for experimental cancer chemotherapy V. Alternative methods for preparation of serum albumin-methotrexate derivative
    • Bures, L., Lichy, A., Bostik, J., and Spundova, M. 1990. The use of protein as a carrier of methotrexate for experimental cancer chemotherapy V. Alternative methods for preparation of serum albumin-methotrexate derivative. Neoplasma 37:225-231.
    • (1990) Neoplasma , vol.37 , pp. 225-231
    • Bures, L.1    Lichy, A.2    Bostik, J.3    Spundova, M.4
  • 16
    • 0016824929 scopus 로고
    • Bulk transfer of fluid in the interstitial compartment of mammary tumors
    • Butler, T. P., Grantham, F. H., and Gullino, P. M. 1975. Bulk transfer of fluid in the interstitial compartment of mammary tumors. Cancer Res. 35:3034-3088.
    • (1975) Cancer Res. , vol.35 , pp. 3034-3088
    • Butler, T.P.1    Grantham, F.H.2    Gullino, P.M.3
  • 17
    • 0030018053 scopus 로고    scopus 로고
    • Neutral lipids production, transport, utilization
    • Cantafora, A., and Blotta, I. 1996. Neutral lipids production, transport, utilization. Anticancer Res. 16:1441-1450.
    • (1996) Anticancer Res. , vol.16 , pp. 1441-1450
    • Cantafora, A.1    Blotta, I.2
  • 18
    • 0025302688 scopus 로고
    • Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: Achievements and prospects
    • Cazzola, M., Bergamaschi, G., Dezza, L., and Arosio, P. 1990. Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: Achievements and prospects. Blood 75:1903-1919.
    • (1990) Blood , vol.75 , pp. 1903-1919
    • Cazzola, M.1    Bergamaschi, G.2    Dezza, L.3    Arosio, P.4
  • 19
    • 0022839492 scopus 로고
    • Effect of different transferrin forms on transferrin-receptor expression, iron uptake, and cellular proliferation of human leukemic HL60 cells. Mechanisms responsible for the specific cytotoxicity of transferrin-gallium
    • Chitambar, C. R., and Seligman, P. A. 1986. Effect of different transferrin forms on transferrin-receptor expression, iron uptake, and cellular proliferation of human leukemic HL60 cells. Mechanisms responsible for the specific cytotoxicity of transferrin-gallium. J. Clin. Invest. 78:1538-1546.
    • (1986) J. Clin. Invest. , vol.78 , pp. 1538-1546
    • Chitambar, C.R.1    Seligman, P.A.2
  • 20
    • 0023262160 scopus 로고
    • Uptake of gallium-67 by human leukemic cells, demonstration of transferrin receptor-dependent and transferrin-independent mechanisms
    • Chitambar, C. R., and Zivkovic, Z. 1987. Uptake of gallium-67 by human leukemic cells, demonstration of transferrin receptor-dependent and transferrin-independent mechanisms. Cancer Res. 47:3929-3934.
    • (1987) Cancer Res. , vol.47 , pp. 3929-3934
    • Chitambar, C.R.1    Zivkovic, Z.2
  • 21
    • 0024209928 scopus 로고
    • Inhibition of leukemic HL60 cell growth by transferrin-gallium, effects on ribonucleotide reductase and demonstration of drug synergy with hydroxy urea
    • Chitambar, C. R., Matthaeus, W. G., Antholine, W. E., Graff, K., and O'Brien, W. J. 1988. Inhibition of leukemic HL60 cell growth by transferrin-gallium, effects on ribonucleotide reductase and demonstration of drug synergy with hydroxy urea. Blood 72:1930-1936.
    • (1988) Blood , vol.72 , pp. 1930-1936
    • Chitambar, C.R.1    Matthaeus, W.G.2    Antholine, W.E.3    Graff, K.4    O'Brien, W.J.5
  • 22
    • 0019415553 scopus 로고
    • Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow, and tumor cells
    • Chu, B. C. P., and Howell, S. P. 1981. Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow, and tumor cells. Biochem. Pharmacol. 30:2545-2552.
    • (1981) Biochem. Pharmacol. , vol.30 , pp. 2545-2552
    • Chu, B.C.P.1    Howell, S.P.2
  • 23
    • 0017336288 scopus 로고
    • High molecular weight derivatives of methotrexate as chemotherapeutic agent
    • Chu, B. C. F., and Whitely, J. M. 1977. High molecular weight derivatives of methotrexate as chemotherapeutic agent. Mol. Pharmacol. 13:80-88.
    • (1977) Mol. Pharmacol. , vol.13 , pp. 80-88
    • Chu, B.C.F.1    Whitely, J.M.2
  • 24
    • 0018340546 scopus 로고
    • Control of solid tumor metastasis with a high-molecular-weight derivative of methotrexate
    • Chu, B. C. F., and Whitely, J. M. 1979. Control of solid tumor metastasis with a high-molecular-weight derivative of methotrexate. J. Natl. Cancer Inst. 62: 79-82.
    • (1979) J. Natl. Cancer Inst. , vol.62 , pp. 79-82
    • Chu, B.C.F.1    Whitely, J.M.2
  • 25
    • 0018832177 scopus 로고
    • The interaction of carrier-bound methotrexate with L1210 cells
    • Chu, B. C. F., and Whitely, J. M. 1980. The interaction of carrier-bound methotrexate with L1210 cells. Mol. Pharmacol. 17:382-387.
    • (1980) Mol. Pharmacol. , vol.17 , pp. 382-387
    • Chu, B.C.F.1    Whitely, J.M.2
  • 26
    • 0022913484 scopus 로고
    • Interaction of human low density lipoprotein and apolipoprotein-B with ternary lipid microemulsion
    • Chun, P. W., Brumbaugh, E. E., and Shireman, R. B. 1986. Interaction of human low density lipoprotein and apolipoprotein-B with ternary lipid microemulsion. Biophys. Chem. 25:223-241.
    • (1986) Biophys. Chem. , vol.25 , pp. 223-241
    • Chun, P.W.1    Brumbaugh, E.E.2    Shireman, R.B.3
  • 28
    • 0025363534 scopus 로고
    • Carrier protein-monensin conjugates: Enhancement of immunotoxin cytotoxicity and potential in tumor treatment
    • Colombatti, M., Dell'Arciprete, L., Chignola, R., and Tridente, G. 1990. Carrier protein-monensin conjugates: Enhancement of immunotoxin cytotoxicity and potential in tumor treatment. Cancer Res. 50:1385-1391.
    • (1990) Cancer Res. , vol.50 , pp. 1385-1391
    • Colombatti, M.1    Dell'Arciprete, L.2    Chignola, R.3    Tridente, G.4
  • 29
    • 0025695510 scopus 로고
    • Prolonged serum half life of antineoplastic drugs by incorporation into the low density lipoprotein
    • De Smidt, P. C., and van Berkel, T. J. C. 1990. Prolonged serum half life of antineoplastic drugs by incorporation into the low density lipoprotein. Cancer Res. 50:7476-7482.
    • (1990) Cancer Res. , vol.50 , pp. 7476-7482
    • De Smidt, P.C.1    Van Berkel, T.J.C.2
  • 30
    • 0030947239 scopus 로고    scopus 로고
    • Preparation, characterization, and properties in vitro and in vivo of a paclitaxel-albumin conjugate
    • Dosio, F., Brusa, P., Crosasso, P., Arpicco, S., and Cattel, L. 1997. Preparation, characterization, and properties in vitro and in vivo of a paclitaxel-albumin conjugate. J. Controlled Release 47:293-304.
    • (1997) J. Controlled Release , vol.47 , pp. 293-304
    • Dosio, F.1    Brusa, P.2    Crosasso, P.3    Arpicco, S.4    Cattel, L.5
  • 31
    • 85038206503 scopus 로고    scopus 로고
    • Superior in vivo efficacy of an acid-sensitive albumin conjugate of adriamycin compared to the parent compound in murine renal cell carcinoma
    • submitted
    • Drevs, J., Hofmann, I., Mormé, D., Unger, C., and Kratz, F. 1998. Superior in vivo efficacy of an acid-sensitive albumin conjugate of adriamycin compared to the parent compound in murine renal cell carcinoma. Drug Del., submitted.
    • (1998) Drug Del.
    • Drevs, J.1    Hofmann, I.2    Mormé, D.3    Unger, C.4    Kratz, F.5
  • 32
    • 0027987791 scopus 로고
    • Polymer conjugates. Pharmacokinetic considerations for design and development
    • Duncan, R., and Spreafico, F. 1994. Polymer conjugates. Pharmacokinetic considerations for design and development. Clin. Pharmacokinet. 27: 290-306.
    • (1994) Clin. Pharmacokinet. , vol.27 , pp. 290-306
    • Duncan, R.1    Spreafico, F.2
  • 33
    • 0023829660 scopus 로고
    • Anticancer agents coupled to N(2-hydroxypropyl) methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia
    • Duncan, R., Kopeckova-Rejmanova, P., Strohalm, J., Hume, I. C., Lloyd, J. B., and Kopecek, J. 1988. Anticancer agents coupled to N(2-hydroxypropyl) methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia. Br. J. Cancer 57:147-156.
    • (1988) Br. J. Cancer , vol.57 , pp. 147-156
    • Duncan, R.1    Kopeckova-Rejmanova, P.2    Strohalm, J.3    Hume, I.C.4    Lloyd, J.B.5    Kopecek, J.6
  • 35
    • 0025666440 scopus 로고
    • Incorporation of prednimustine into low density lipoprotein: Activity against P388 cells in tissue culture
    • Eley, J. G., Halbert, G. W., and Florence, A. T. 1990a. Incorporation of prednimustine into low density lipoprotein: Activity against P388 cells in tissue culture. Int. J. Pharm. 65:219-224.
    • (1990) Int. J. Pharm. , vol.65 , pp. 219-224
    • Eley, J.G.1    Halbert, G.W.2    Florence, A.T.3
  • 36
    • 0025081186 scopus 로고
    • The incorporation of estramustine into low density lipoprotein and its activity in tissue culture
    • Eley, J. G., Halbert, G. W., and Florence, A. T. 1990b. The incorporation of estramustine into low density lipoprotein and its activity in tissue culture. Int. J. Pharm. 63:121.
    • (1990) Int. J. Pharm. , vol.63 , pp. 121
    • Eley, J.G.1    Halbert, G.W.2    Florence, A.T.3
  • 37
    • 2442738890 scopus 로고
    • Preliminary results on 11 advanced breast cancer patients treated with cisplatin complexed to human transferrin
    • Elliott, R. L., Elliott, M. C., and Head, J. F. 1990. Preliminary results on 11 advanced breast cancer patients treated with cisplatin complexed to human transferrin. Breast Cancer Res. Treat. 16:169.
    • (1990) Breast Cancer Res. Treat. , vol.16 , pp. 169
    • Elliott, R.L.1    Elliott, M.C.2    Head, J.F.3
  • 38
    • 0023718880 scopus 로고
    • Preliminary evaluation of platinum transferrin (MPTC-63) as a potential nontoxic treatment for breast cancer
    • Elliott, R. L., Stjernholm, R., and Elliott, M. C. 1988. Preliminary evaluation of platinum transferrin (MPTC-63) as a potential nontoxic treatment for breast cancer. Cancer Detect. Prev. 12:469-480.
    • (1988) Cancer Detect. Prev. , vol.12 , pp. 469-480
    • Elliott, R.L.1    Stjernholm, R.2    Elliott, M.C.3
  • 39
    • 0025397802 scopus 로고
    • Preliminary clinical study of transferrin-adriamycin conjugate for drug delivery to acute leukemia patients
    • Faulk, W. P., Taylor, C. G., Yeh, C. J., and McIntyre, J. A. 1990. Preliminary clinical study of transferrin-adriamycin conjugate for drug delivery to acute leukemia patients. Mol. Biother. 2:57-60.
    • (1990) Mol. Biother. , vol.2 , pp. 57-60
    • Faulk, W.P.1    Taylor, C.G.2    Yeh, C.J.3    McIntyre, J.A.4
  • 41
    • 0028386492 scopus 로고
    • Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells
    • Firestone, R. A. 1994. Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells. Bioconjugate Chem. 5:105-113.
    • (1994) Bioconjugate Chem. , vol.5 , pp. 105-113
    • Firestone, R.A.1
  • 42
  • 46
    • 0842279809 scopus 로고
    • Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors
    • Gabizon, A., and Papahadjopoulous, D. 1988. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors. Proc. Natl. Acad. Sci. USA 85:6949-6953.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6949-6953
    • Gabizon, A.1    Papahadjopoulous, D.2
  • 47
    • 0028577325 scopus 로고
    • In vitro antiproliferative effects of albumin-doxorubicin conjugates against Ewing's sarcoma and peripheral neuroectodermal tumor cells
    • Gabor, F., Wollmann, K., Theyer, G., Haberl, I., and Hamilton, G. 1994. In vitro antiproliferative effects of albumin-doxorubicin conjugates against Ewing's sarcoma and peripheral neuroectodermal tumor cells. Anticancer Res. 14: 1943-1950.
    • (1994) Anticancer Res. , vol.14 , pp. 1943-1950
    • Gabor, F.1    Wollmann, K.2    Theyer, G.3    Haberl, I.4    Hamilton, G.5
  • 48
    • 0019454263 scopus 로고
    • Cholesterol metabolism in cancer cells in monolayer culture: III. Low-density lipoprotein metabolism
    • Gal, D., MacDonald, P. C., Porter, J. C., and Simpson, E. R. 1981a. Cholesterol metabolism in cancer cells in monolayer culture: III. Low-density lipoprotein metabolism. Int. J. Cancer 28:315-319.
    • (1981) Int. J. Cancer , vol.28 , pp. 315-319
    • Gal, D.1    MacDonald, P.C.2    Porter, J.C.3    Simpson, E.R.4
  • 49
    • 0019453214 scopus 로고
    • Low-density lipoprotein as a potential vehicle for chemotherapeutic agents and radionucleotides in the management of gynecologic neoplasm
    • Gal, D., Ottashi, M., MacDonald, P. C., Buschbaum, H. J., and Simpson, E. R. 1981b. Low-density lipoprotein as a potential vehicle for chemotherapeutic agents and radionucleotides in the management of gynecologic neoplasm. Am. J. Obstet. Gynecol. 139:877-885.
    • (1981) Am. J. Obstet. Gynecol. , vol.139 , pp. 877-885
    • Gal, D.1    Ottashi, M.2    MacDonald, P.C.3    Buschbaum, H.J.4    Simpson, E.R.5
  • 50
    • 0020079844 scopus 로고
    • Defective internalization of low density lipoprotein in epidermoid cervical cancer cells
    • Gal, D., Simpson, E. R., Porter, J. C., and Snyder, J. M. 1982. Defective internalization of low density lipoprotein in epidermoid cervical cancer cells. J. Cell Biol 92:597-603.
    • (1982) J. Cell Biol , vol.92 , pp. 597-603
    • Gal, D.1    Simpson, E.R.2    Porter, J.C.3    Snyder, J.M.4
  • 52
    • 0017354135 scopus 로고
    • The low-density lipoprotein pathway and its relation to artherosclerosis
    • Goldstein, J. L., and Brown, M. S. 1977. The low-density lipoprotein pathway and its relation to artherosclerosis. Ann. Rev. Biochem. 46:897-930.
    • (1977) Ann. Rev. Biochem. , vol.46 , pp. 897-930
    • Goldstein, J.L.1    Brown, M.S.2
  • 53
    • 0023205060 scopus 로고
    • Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity
    • Greenfield, L., Johnson, V. G., and Youle, R. L. 1987. Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity. Science 238:536-539.
    • (1987) Science , vol.238 , pp. 536-539
    • Greenfield, L.1    Johnson, V.G.2    Youle, R.L.3
  • 55
    • 0024435933 scopus 로고
    • Albumin microspheres II: Application in drug delivery
    • Gupta, P. K., and Hung, C. T. 1989b. Albumin microspheres II: Application in drug delivery. J. Microencapsulation 6:427-462.
    • (1989) J. Microencapsulation , vol.6 , pp. 427-462
    • Gupta, P.K.1    Hung, C.T.2
  • 56
    • 0024435933 scopus 로고
    • Albumin microspheres I: Physiochemical characteristics
    • Gupta, P. K., and Hung, C. T. 1989a. Albumin microspheres I: Physiochemical characteristics. J. Microencapsulation 6:463-472.
    • (1989) J. Microencapsulation , vol.6 , pp. 463-472
    • Gupta, P.K.1    Hung, C.T.2
  • 57
    • 0026608651 scopus 로고
    • In vitro efficacy of transferrin-toxin conjugates against glioblastoma multiforme
    • Hall, W. A., Godal, A., Juell, S., and Fodstad, O. 1992. In vitro efficacy of transferrin-toxin conjugates against glioblastoma multiforme. J. Neurosurg. 76:838-844.
    • (1992) J. Neurosurg. , vol.76 , pp. 838-844
    • Hall, W.A.1    Godal, A.2    Juell, S.3    Fodstad, O.4
  • 59
    • 0026664548 scopus 로고
    • Atomic structure and chemistry of human serum albumin
    • He, X. M., and Carter, D. C. 1992. Atomic structure and chemistry of human serum albumin. Nature. 358:209-215.
    • (1992) Nature , vol.358 , pp. 209-215
    • He, X.M.1    Carter, D.C.2
  • 60
    • 0024343139 scopus 로고
    • Hypocholesterolemia and increased elimination of low-density lipoproteins in metastatic cancer of the prostate
    • Henriksson, P., Ericsson, S., Stege, R., Ericsson, M., Rudling, M., Berglund, R., and Angelin, B. 1989. Hypocholesterolemia and increased elimination of low-density lipoproteins in metastatic cancer of the prostate. Lancet II: 1178-1180.
    • (1989) Lancet , vol.2 , pp. 1178-1180
    • Henriksson, P.1    Ericsson, S.2    Stege, R.3    Ericsson, M.4    Rudling, M.5    Berglund, R.6    Angelin, B.7
  • 61
    • 0018181378 scopus 로고
    • Low density lipoprotein (LDL) receptor activity in human acute myelogenous leukemic cells
    • Ho, Y. K., Smith, R. G., Brown, M. S., and Goldstein, J. L. 1978. Low density lipoprotein (LDL) receptor activity in human acute myelogenous leukemic cells. Blood 52:1099-1114.
    • (1978) Blood , vol.52 , pp. 1099-1114
    • Ho, Y.K.1    Smith, R.G.2    Brown, M.S.3    Goldstein, J.L.4
  • 62
    • 0028876664 scopus 로고
    • In vitro cytotoxicities and in vivo distribution of transferrin-platinum(II) complex
    • Hoshino, T., Misaki, M., Yamamoto, M., Shimizu, H., Ogawa, Y., and Toguchi, H. 1994. In vitro cytotoxicities and in vivo distribution of transferrin-platinum(II) complex. J. Pharm. Sci. 84:216-221.
    • (1994) J. Pharm. Sci. , vol.84 , pp. 216-221
    • Hoshino, T.1    Misaki, M.2    Yamamoto, M.3    Shimizu, H.4    Ogawa, Y.5    Toguchi, H.6
  • 65
    • 0026534439 scopus 로고
    • Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression
    • Ishiguro, K., Ho, P. T., and Sartorelli, A. C. 1992. Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression. Somat. Cell. Mol. Genet. 18:45-63.
    • (1992) Somat. Cell. Mol. Genet. , vol.18 , pp. 45-63
    • Ishiguro, K.1    Ho, P.T.2    Sartorelli, A.C.3
  • 66
    • 0021351230 scopus 로고
    • Preparation and interaction of a low-density lipoprotein daunomycin complex with P388 leukemic cells
    • Iwanik, M. J., Shaw, K. V., Leswith, B. J., Yanovich, S., and Shaw, J. M. 1984. Preparation and interaction of a low-density lipoprotein daunomycin complex with P388 leukemic cells. Cancer Res. 44:1206-1215.
    • (1984) Cancer Res. , vol.44 , pp. 1206-1215
    • Iwanik, M.J.1    Shaw, K.V.2    Leswith, B.J.3    Yanovich, S.4    Shaw, J.M.5
  • 67
    • 0023481357 scopus 로고
    • Transport of molecules across tumor vaculature
    • Jain, R. K. 1987a. Transport of molecules across tumor vaculature. Cancer Metast. Rev. 6:559-593.
    • (1987) Cancer Metast. Rev. , vol.6 , pp. 559-593
    • Jain, R.K.1
  • 68
    • 0023219734 scopus 로고
    • Transport of molecules in the tumor interstitium: A review
    • Jain, R. K. 1987b. Transport of molecules in the tumor interstitium: A review. Cancer Res. 47:3039-3051.
    • (1987) Cancer Res. , vol.47 , pp. 3039-3051
    • Jain, R.K.1
  • 70
    • 0023838032 scopus 로고
    • The role of the diphtheria toxin receptor in cytosol translocation
    • Johnson, V. G., Wilson, G., Greenfield, L., and Youle, R. J. 1988. The role of the diphtheria toxin receptor in cytosol translocation. J. Biol. Chem. 263: 1295-130.
    • (1988) J. Biol. Chem. , vol.263 , pp. 1295-2130
    • Johnson, V.G.1    Wilson, G.2    Greenfield, L.3    Youle, R.J.4
  • 71
    • 0002855171 scopus 로고
    • New tumor-inhibiting ruthenium complexes
    • ed. B. K. Keppler, Verlag Chemie, VCH, Weinheim: Verlag Chemie, VCH
    • Keppler, B. K., Lipponer, K.-G., Stenzel, B., and Kratz, F. 1993. New tumor-inhibiting ruthenium complexes. In Metal Complexes in Cancer Chemotherapy, ed. B. K. Keppler, 187-220, Verlag Chemie, VCH, Weinheim: Verlag Chemie, VCH.
    • (1993) Metal Complexes in Cancer Chemotherapy , pp. 187-220
    • Keppler, B.K.1    Lipponer, K.-G.2    Stenzel, B.3    Kratz, F.4
  • 72
    • 0023733222 scopus 로고
    • Comparative cellular uptake an cytotoxicity of a complex of daunomycinlow density lipoprotein in human squamous lung tumour cell monolayers
    • Kerr, D. J., Hynds, S. A., Shepherd, J., Packard, C. J., and Kaye, S. B. 1988. Comparative cellular uptake an cytotoxicity of a complex of daunomycinlow density lipoprotein in human squamous lung tumour cell monolayers. Biochem. Pharmacol. 37:3981-3986.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 3981-3986
    • Kerr, D.J.1    Hynds, S.A.2    Shepherd, J.3    Packard, C.J.4    Kaye, S.B.5
  • 74
    • 0344119716 scopus 로고
    • Transferrin receptor of tumor cells - Potential tools for diagnosis and treatment of malignancies
    • eds. G. Spik, J. Montreuil, R. R. Crichton, and J. Mazurier, Amsterdam: Elsevier Science Publishers
    • Kohgo, Y., Niitsu, Y., Nishisato, T., Urushizaki, Y., Kondo, H., Fukushima, M., Tsushima, M., and Urushizaki, I. 1985. Transferrin receptor of tumor cells - potential tools for diagnosis and treatment of malignancies. In Proteins of Iron Storage and Transport, eds. G. Spik, J. Montreuil, R. R. Crichton, and J. Mazurier, 155-169, Amsterdam: Elsevier Science Publishers.
    • (1985) Proteins of Iron Storage and Transport , pp. 155-169
    • Kohgo, Y.1    Niitsu, Y.2    Nishisato, T.3    Urushizaki, Y.4    Kondo, H.5    Fukushima, M.6    Tsushima, M.7    Urushizaki, I.8
  • 75
    • 0025729034 scopus 로고
    • Assessment of ligand effects in intracellular trafficking of ricin A chain using anti-ricin hybridomas
    • Kornfeld, S. B., Leonard, J. E., Mullen, M. D., and Taetle, R. 1991. Assessment of ligand effects in intracellular trafficking of ricin A chain using anti-ricin hybridomas. Cancer Res. 51:4316-4322.
    • (1991) Cancer Res. , vol.51 , pp. 4316-4322
    • Kornfeld, S.B.1    Leonard, J.E.2    Mullen, M.D.3    Taetle, R.4
  • 76
    • 0002792021 scopus 로고
    • Interactions of antitumour metal complexes with serum proteins. Perspectives for anticancer drug development. A review
    • ed. B. K. Keppler, Verlag Chemie Weinhein
    • Kratz, F. 1993. Interactions of antitumour metal complexes with serum proteins. Perspectives for anticancer drug development. A review. In Metal Complexes as Antitumour Agents, ed. B. K. Keppler, 392-429, Verlag Chemie Weinhein.
    • (1993) Metal Complexes as Antitumour Agents , pp. 392-429
    • Kratz, F.1
  • 77
    • 0028821123 scopus 로고
    • Drug targeting in der antitumoralen Chemotheraple. Antigene und Rezeptoren als Angriffspunkte einer selektiven Chemotherapie
    • Kratz, F. 1995. Drug targeting in der antitumoralen Chemotheraple. Antigene und Rezeptoren als Angriffspunkte einer selektiven Chemotherapie. Pharmazie in unserer Zeit 24:14-26.
    • (1995) Pharmazie in Unserer Zeit , vol.24 , pp. 14-26
    • Kratz, F.1
  • 79
  • 81
    • 0031552150 scopus 로고    scopus 로고
    • Synthesis of new maleimide derivatives of daunorubicin and biological activity of acid labile transferrin conjugates
    • Kratz, F., Beyer, U., Schumacher, P., Krüger, M., Zahn, H., Roth, T., Fiebig, H. H., and Unger, C. 1997a. Synthesis of new maleimide derivatives of daunorubicin and biological activity of acid labile transferrin conjugates. Bioorg. Med. Chem. Lett. 7:617-622.
    • (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 617-622
    • Kratz, F.1    Beyer, U.2    Schumacher, P.3    Krüger, M.4    Zahn, H.5    Roth, T.6    Fiebig, H.H.7    Unger, C.8
  • 82
    • 0009211348 scopus 로고    scopus 로고
    • Antitumor activity of acid labile transferrin and albumin doxorubicin conjugates in vitro and in vivo human tumour xenograft models
    • Kratz, F., Fichtner, I., Beyer, U., Schumacher, P., Roth, T., Fiebig, H. H., and Unger, C. 1997b. Antitumor activity of acid labile transferrin and albumin doxorubicin conjugates in vitro and in vivo human tumour xenograft models. Eur. J. Cancer 33:784.
    • (1997) Eur. J. Cancer , vol.33 , pp. 784
    • Kratz, F.1    Fichtner, I.2    Beyer, U.3    Schumacher, P.4    Roth, T.5    Fiebig, H.H.6    Unger, C.7
  • 83
    • 0027993919 scopus 로고
    • The binding properties of two ontitumor ruthenium(III) complexes to apotransferrin
    • Kratz, F., Hartmann, M., Keppler, B. K., and Messori, L. 1994a. The binding properties of two ontitumor ruthenium(III) complexes to apotransferrin. J. Biol. Chem. 269:2581-2588.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2581-2588
    • Kratz, F.1    Hartmann, M.2    Keppler, B.K.3    Messori, L.4
  • 84
    • 0029868406 scopus 로고    scopus 로고
    • Comparison of the antiproliferative activity of two antitumour ruthenium(III) complexes with their apotransferrin and transferrin-bound forms in a human colon cancer cell line
    • Kratz, F., Keppler, B. K., Hartmann, M., Messori, L., and Berger, M. R. 1996. Comparison of the antiproliferative activity of two antitumour ruthenium(III) complexes with their apotransferrin and transferrin-bound forms in a human colon cancer cell line. Metal-Based Drugs 3:15-23.
    • (1996) Metal-Based Drugs , vol.3 , pp. 15-23
    • Kratz, F.1    Keppler, B.K.2    Hartmann, M.3    Messori, L.4    Berger, M.R.5
  • 85
    • 0000459043 scopus 로고
    • Protein-binding properties of two antitumour Ru(III) complexes to human apotransferrin and apolactoferrin
    • Kratz, F., Keppler, B. K., Messori, L., Smith, C., and Baker, E. N. 1994b. Protein-binding properties of two antitumour Ru(III) complexes to human apotransferrin and apolactoferrin. Metal-based Drugs 1:169-173.
    • (1994) Metal-based Drugs , vol.1 , pp. 169-173
    • Kratz, F.1    Keppler, B.K.2    Messori, L.3    Smith, C.4    Baker, E.N.5
  • 86
    • 0002069966 scopus 로고
    • Kinetic, spectroscopic and LPLC studies of the interactions of antitumour ruthenium(III) complexes with serum proteins
    • John Paris: John Libbey Limited Eurotext
    • Kratz, F., Mulinacci, N., Messori, L., Bertini, I., and Keppler, B. K. 1992. Kinetic, spectroscopic and LPLC studies of the interactions of antitumour ruthenium(III) complexes with serum proteins. In Metal Ions in Biology and Medicine, Vol. 2, 69-74, John Paris: John Libbey Limited Eurotext.
    • (1992) Metal Ions in Biology and Medicine , vol.2 , pp. 69-74
    • Kratz, F.1    Mulinacci, N.2    Messori, L.3    Bertini, I.4    Keppler, B.K.5
  • 89
    • 0031656004 scopus 로고    scopus 로고
    • Anticancer metal complexes and tumor targeting strategies
    • Kratz, F., and Schütte, M. T. 1998. Anticancer metal complexes and tumor targeting strategies. Cancer J. 11:176-181.
    • (1998) Cancer J. , vol.11 , pp. 176-181
    • Kratz, F.1    Schütte, M.T.2
  • 90
    • 0017828622 scopus 로고
    • Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate
    • Krieger, M., Brown, M. S., Faust, J. R., and Goldstein, J. L. 1978. Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. J. Biol. Chem. 253:4093-4101.
    • (1978) J. Biol. Chem. , vol.253 , pp. 4093-4101
    • Krieger, M.1    Brown, M.S.2    Faust, J.R.3    Goldstein, J.L.4
  • 91
    • 0025821178 scopus 로고
    • Changes in plasma lipid and lipoprotein cholesterol and weight prior to the diagnosis of cancer
    • Kritchevsky, S. B., Wilcosky, T. C., Morris, D. L., Truong, K. N., and Tyroler, H. A. 1991. Changes in plasma lipid and lipoprotein cholesterol and weight prior to the diagnosis of cancer. Cancer Res. 51:3198-3203.
    • (1991) Cancer Res. , vol.51 , pp. 3198-3203
    • Kritchevsky, S.B.1    Wilcosky, T.C.2    Morris, D.L.3    Truong, K.N.4    Tyroler, H.A.5
  • 92
    • 0342460614 scopus 로고    scopus 로고
    • Synthesis and stability of four maleimide derivatives of the anticancer drug doxorubicin for the preparation of chemoimmunoconjugates
    • Krüger, M., Beyer, U., Schumacher, P., Unger, C., Zahn, H., and Kratz, F. 1997. Synthesis and stability of four maleimide derivatives of the anticancer drug doxorubicin for the preparation of chemoimmunoconjugates. Chem. Pharm. Bull. 47:399-401.
    • (1997) Chem. Pharm. Bull. , vol.47 , pp. 399-401
    • Krüger, M.1    Beyer, U.2    Schumacher, P.3    Unger, C.4    Zahn, H.5    Kratz, F.6
  • 93
    • 0025763413 scopus 로고
    • A toxin-resistant mouse L-cell mutant defective in protein transport along the secretory pathway
    • Laurie, S. M., and Robbins, A. R. 1991. A toxin-resistant mouse L-cell mutant defective in protein transport along the secretory pathway. J. Cell Physiol. 147:215-223.
    • (1991) J. Cell Physiol. , vol.147 , pp. 215-223
    • Laurie, S.M.1    Robbins, A.R.2
  • 94
    • 0027081660 scopus 로고
    • In vivo cytotoxicity and antineoplastic activity of a transferrin-daunorubicin conjugate
    • Lemieux, P., Pagé, M., and Noel, C. 1992. In vivo cytotoxicity and antineoplastic activity of a transferrin-daunorubicin conjugate. In Vivo 6:621-628.
    • (1992) In Vivo , vol.6 , pp. 621-628
    • Lemieux, P.1    Pagé, M.2    Noel, C.3
  • 96
    • 0023270613 scopus 로고
    • Preparation of drug-low density lipoprotein complexes for delivery of antitumoral drugs via the low density lipoprotein pathway
    • Lundberg, B. 1987. Preparation of drug-low density lipoprotein complexes for delivery of antitumoral drugs via the low density lipoprotein pathway. Cancer Res. 47:4105-1108.
    • (1987) Cancer Res. , vol.47 , pp. 4105-11108
    • Lundberg, B.1
  • 97
    • 0026556926 scopus 로고
    • Assembly of prednimustine low-density lipoprotein complexes and their cytotoxic activity in tissue culture
    • Lundberg, B. 1992. Assembly of prednimustine low-density lipoprotein complexes and their cytotoxic activity in tissue culture. Cancer Chemother. Pharmacol. 29:241-247.
    • (1992) Cancer Chemother. Pharmacol. , vol.29 , pp. 241-247
    • Lundberg, B.1
  • 98
    • 0021164513 scopus 로고
    • Preparation of biologically active analogs of serum low density proteins
    • Lundberg, B., and Suominen, L. 1984. Preparation of biologically active analogs of serum low density proteins. J. Lipid Res. 25:550-558.
    • (1984) J. Lipid Res. , vol.25 , pp. 550-558
    • Lundberg, B.1    Suominen, L.2
  • 99
    • 0024839642 scopus 로고
    • Tumoritropic and lymphotropic principles macromolecular prodrugs
    • Maeda, H., and Matsumura, Y. 1989. Tumoritropic and lymphotropic principles macromolecular prodrugs. Crit. Rev. Ther. Drug Carrier Sys. 6:193-210.
    • (1989) Crit. Rev. Ther. Drug Carrier Sys. , vol.6 , pp. 193-210
    • Maeda, H.1    Matsumura, Y.2
  • 100
    • 0022476847 scopus 로고
    • Low-density lipoprotein as a carrier antitumoral drugs: In vivo fate of drug-human low-density lipoprotein complexes in mice
    • Masquelier, M., Vitols, S., and Peterson, C. 1986. Low-density lipoprotein as a carrier antitumoral drugs: In vivo fate of drug-human low-density lipoprotein complexes in mice. Cancer Res. 46:3842-3847.
    • (1986) Cancer Res. , vol.46 , pp. 3842-3847
    • Masquelier, M.1    Vitols, S.2    Peterson, C.3
  • 101
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins of the antitumor agent smancs
    • Matsumura, Y., and Maeda, H. 1986. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins of the antitumor agent smancs. Cancer Res. 46:6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 102
    • 0025235971 scopus 로고
    • Chemical modification of proteins: History and application
    • Means, G. E., and Feeney, R. E. 1990. Chemical modification of proteins: History and application. Bioconjugate Chem. 1:2-12.
    • (1990) Bioconjugate Chem. , vol.1 , pp. 2-12
    • Means, G.E.1    Feeney, R.E.2
  • 103
    • 0006017507 scopus 로고
    • Transferrin - From inorganic biochemistry to medicine
    • Messori, L., and Kratz, F. 1994. Transferrin - from inorganic biochemistry to medicine. Metal-based Drugs 1:161-167.
    • (1994) Metal-based Drugs , vol.1 , pp. 161-167
    • Messori, L.1    Kratz, F.2
  • 104
    • 0000118455 scopus 로고
    • Effects of Walker carcinoma 256 on food intake, body weight, and nitrogen metabolism of growing rats
    • Mider, G. B., Tesluk, H., and Morton, J. J. 1948. Effects of Walker carcinoma 256 on food intake, body weight, and nitrogen metabolism of growing rats. Acta Union Int. Contra Cancrum 6:409-420.
    • (1948) Acta Union Int. Contra Cancrum , vol.6 , pp. 409-420
    • Mider, G.B.1    Tesluk, H.2    Morton, J.J.3
  • 108
    • 0028866688 scopus 로고
    • Circumvention of multidrug resistance in neoplastic cells through scavenger receptor mediated drug delivery
    • Mukhopadhyay, A., Mukhopadhyay, B., and Basu, S. K. 1995. Circumvention of multidrug resistance in neoplastic cells through scavenger receptor mediated drug delivery. FEBS Lett. 376:95-98.
    • (1995) FEBS Lett. , vol.376 , pp. 95-98
    • Mukhopadhyay, A.1    Mukhopadhyay, B.2    Basu, S.K.3
  • 109
    • 0024414652 scopus 로고
    • Enhancement of immunotoxin efficacy by acid-cleavable cross-linking agents utilizing diphtheria toxin and toxin mutants
    • Neville, D. M. Jr., Srinavasachar, K., Stone, R., and Scharff, J. 1989. Enhancement of immunotoxin efficacy by acid-cleavable cross-linking agents utilizing diphtheria toxin and toxin mutants. J. Biol. Chem. 264:14653-14661.
    • (1989) J. Biol. Chem. , vol.264 , pp. 14653-14661
    • Neville Jr., D.M.1    Srinavasachar, K.2    Stone, R.3    Scharff, J.4
  • 110
    • 0021685106 scopus 로고
    • In vivo assimilation of low-density lipoproteins by a fibrosarcoma tumour cell line in mice
    • Norata, G., Canti, G., Ricci, L., Nicolin, A., Trezzi, E., and Capatano, A. L. 1984. In vivo assimilation of low-density lipoproteins by a fibrosarcoma tumour cell line in mice. Cancer Lett. 25:203-208.
    • (1984) Cancer Lett. , vol.25 , pp. 203-208
    • Norata, G.1    Canti, G.2    Ricci, L.3    Nicolin, A.4    Trezzi, E.5    Capatano, A.L.6
  • 111
    • 0027414822 scopus 로고
    • Chemotherapeutic efficacy of the protein-doxorubicin conjugates on multidrug resistant rat hepatoma cell line in vitro
    • Ohkawa, K., Hatano, T., Tsukada, Y., Matsuda, M. 1993a. Chemotherapeutic efficacy of the protein-doxorubicin conjugates on multidrug resistant rat hepatoma cell line in vitro. Br. J. Cancer 67:274-278.
    • (1993) Br. J. Cancer , vol.67 , pp. 274-278
    • Ohkawa, K.1    Hatano, T.2    Tsukada, Y.3    Matsuda, M.4
  • 112
    • 0027816261 scopus 로고
    • Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma
    • Ohkawa, K., Hatano, T., Yamada, K., Joh, K., Takada, K., Tsukada, Y., and Matsuda, M. 1993b. Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma. Cancer Res. 53:4238-4242.
    • (1993) Cancer Res. , vol.53 , pp. 4238-4242
    • Ohkawa, K.1    Hatano, T.2    Yamada, K.3    Joh, K.4    Takada, K.5    Tsukada, Y.6    Matsuda, M.7
  • 113
    • 0021991868 scopus 로고
    • Characterization of a transferrin-diphtheria toxin conjugate
    • O'Keefe, D. O., and Draper, R. K. 1985. Characterization of a transferrin-diphtheria toxin conjugate. J. Biol. Chem. 260:932-937.
    • (1985) J. Biol. Chem. , vol.260 , pp. 932-937
    • O'Keefe, D.O.1    Draper, R.K.2
  • 114
    • 0024077467 scopus 로고
    • Two pathways of transferrin recycling evident in a variant of mouse LMTK-cells
    • O'Keefe, D. O., and Draper, R. K. 1988. Two pathways of transferrin recycling evident in a variant of mouse LMTK-cells. Somat. Cell. Mol. Genet. 14:473-487.
    • (1988) Somat. Cell. Mol. Genet. , vol.14 , pp. 473-487
    • O'Keefe, D.O.1    Draper, R.K.2
  • 115
    • 0029786047 scopus 로고    scopus 로고
    • Brain drug delivery and blood-brain barrier transport
    • Partridge, W. M. 1996. Brain drug delivery and blood-brain barrier transport. Drug Del. 3:99-115.
    • (1996) Drug Del. , vol.3 , pp. 99-115
    • Partridge, W.M.1
  • 117
    • 0022384934 scopus 로고
    • Hypocholesterolemia in cancer patients may be caused by elevated LDL receptor activities in malignant cells
    • Peterson, C., Vitols, S., Rudling, M., Blomgren, H., Edsmyr, F., and Skoog, L. 1985. Hypocholesterolemia in cancer patients may be caused by elevated LDL receptor activities in malignant cells. Med. Oncol. Tumor Pharmacother. 2:143-147.
    • (1985) Med. Oncol. Tumor Pharmacother. , vol.2 , pp. 143-147
    • Peterson, C.1    Vitols, S.2    Rudling, M.3    Blomgren, H.4    Edsmyr, F.5    Skoog, L.6
  • 119
    • 0021330893 scopus 로고
    • A highly cytotoxic human transferrin-ricin. A chain conjugate used to select receptor-modified cells
    • Raso, V., and Basala, M. 1984. A highly cytotoxic human transferrin-ricin. A chain conjugate used to select receptor-modified cells. J. Biol. Chem. 259:1143-1149.
    • (1984) J. Biol. Chem. , vol.259 , pp. 1143-1149
    • Raso, V.1    Basala, M.2
  • 120
    • 0021231808 scopus 로고
    • Carboxylic ionophores enhance the cytotoxic potency of ligand- And antibody-delivered ricin A chain
    • Raso, V., and Lawrence, J. 1984. Carboxylic ionophores enhance the cytotoxic potency of ligand- and antibody-delivered ricin A chain. J. Exp. Med. 160:1234-1240.
    • (1984) J. Exp. Med. , vol.160 , pp. 1234-1240
    • Raso, V.1    Lawrence, J.2
  • 123
    • 0025840179 scopus 로고
    • Cytotoxic potential of ribonuclease and ribonuclease hybrid proteins
    • Rybak, S. M., Saxena, S. K., Ackerman, E. J., and Youle, R. J. 1991. Cytotoxic potential of ribonuclease and ribonuclease hybrid proteins. J. Biol. Chem. 266:21202-21207.
    • (1991) J. Biol. Chem. , vol.266 , pp. 21202-21207
    • Rybak, S.M.1    Saxena, S.K.2    Ackerman, E.J.3    Youle, R.J.4
  • 124
    • 0023906184 scopus 로고
    • Correlation of vascular permeability and blood flow with monoclonal antibody uptake by human clouser and renal cell xenografts
    • Sands, H., Jones, P. L., Shah, A. S., Palme, D., Vessella, R. L., and Gallagher, B. M. 1988. Correlation of vascular permeability and blood flow with monoclonal antibody uptake by human clouser and renal cell xenografts. Cancer Res. 48:188-193.
    • (1988) Cancer Res. , vol.48 , pp. 188-193
    • Sands, H.1    Jones, P.L.2    Shah, A.S.3    Palme, D.4    Vessella, R.L.5    Gallagher, B.M.6
  • 126
    • 2442761266 scopus 로고    scopus 로고
    • Characterization of vascular permeability in human tumor xenografts-identification of suitable tumor models to evaluate polymer conjugates
    • 15-17.10.1997, Tumor Biology Center, Freiburg, FRG
    • Schaler, J., Fiebig, H. H., Sausville, E. A., and Burger, A. M. 1997. Characterization of vascular permeability in human tumor xenografts-identification of suitable tumor models to evaluate polymer conjugates. Int. Symposium "Relevance of Tumor Models for Anticancer Drug Development" P6, 15-17.10.1997, Tumor Biology Center, Freiburg, FRG.
    • (1997) Int. Symposium "Relevance of Tumor Models for Anticancer Drug Development" , pp. 6
    • Schaler, J.1    Fiebig, H.H.2    Sausville, E.A.3    Burger, A.M.4
  • 127
    • 0026694788 scopus 로고
    • Passive tumor targeting of soluble macromolecules and drug conjugates
    • Seymour, L. W. 1992. Passive tumor targeting of soluble macromolecules and drug conjugates. Crit. Rev. Ther. Drug Carrier Sys. 9:135-187.
    • (1992) Crit. Rev. Ther. Drug Carrier Sys. , vol.9 , pp. 135-187
    • Seymour, L.W.1
  • 128
    • 0029039418 scopus 로고
    • Influence of molecular weight on passive tumour accumulation of a soluble macromolecular carrier
    • Seymour, L. W., Miyamoto, Y., Maeda, H., Brereton, M., Strohalm, J., Ulbrich, K., and Ouncon, R. 1995. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular carrier. Eur. J. Cancer 31A: 766-770.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 766-770
    • Seymour, L.W.1    Miyamoto, Y.2    Maeda, H.3    Brereton, M.4    Strohalm, J.5    Ulbrich, K.6    Ouncon, R.7
  • 130
    • 0001752711 scopus 로고    scopus 로고
    • Binding of ruthenium(III) anti-tumor drugs to human lactoferrin by high resolution X-ray crystallographic structure analysis
    • Smith, C. A., Sutherland-Smith, A. J., Keppler, B. K., Kratz, F., and Baker, E. N. 1996. Binding of ruthenium(III) anti-tumor drugs to human lactoferrin by high resolution X-ray crystallographic structure analysis. J. Bioinorg. Chem. 1:424-431.
    • (1996) J. Bioinorg. Chem. , vol.1 , pp. 424-431
    • Smith, C.A.1    Sutherland-Smith, A.J.2    Keppler, B.K.3    Kratz, F.4    Baker, E.N.5
  • 138
    • 0026584015 scopus 로고
    • Polymers containing enzymatically degradable bonds. XII. Release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymers
    • Subr, V., Strohalm, J., Ulbrich, K., and Duncan, R. 1992. Polymers containing enzymatically degradable bonds. XII. Release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymers. J. Controlled Release 18:123-132.
    • (1992) J. Controlled Release , vol.18 , pp. 123-132
    • Subr, V.1    Strohalm, J.2    Ulbrich, K.3    Duncan, R.4
  • 139
    • 0026533651 scopus 로고
    • Inhibition of transplasma membrane electron transport by transferrin-adriamycin conjugates
    • Sun, I. L., Sun, E. E., Crane, F. L., Morre, D. J., and Faulk, W. P. 1992. Inhibition of transplasma membrane electron transport by transferrin-adriamycin conjugates. Biochim. Biophys. Acta 1105:84-88.
    • (1992) Biochim. Biophys. Acta , vol.1105 , pp. 84-88
    • Sun, I.L.1    Sun, E.E.2    Crane, F.L.3    Morre, D.J.4    Faulk, W.P.5
  • 140
    • 0019586989 scopus 로고
    • Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin
    • Sutherland, R., Delia, D., Schneider, C., Newmann, R., Kemshead, J., and Greaves, M. 1980. Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proc. Natl. Acad. Sci. USA 78:4515-4519.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4515-4519
    • Sutherland, R.1    Delia, D.2    Schneider, C.3    Newmann, R.4    Kemshead, J.5    Greaves, M.6
  • 141
    • 0002079949 scopus 로고
    • Disposition and tumor localization of mitomycin C dextran conjugates in mice
    • Takakura, Y., Fujita, T., Hashida, M., and Sezaki, H. 1987. Disposition and tumor localization of mitomycin C dextran conjugates in mice. Pharm. Res. 4:293-300.
    • (1987) Pharm. Res. , vol.4 , pp. 293-300
    • Takakura, Y.1    Fujita, T.2    Hashida, M.3    Sezaki, H.4
  • 142
    • 0025148495 scopus 로고
    • Disposition characteristics of macromolecules in tumor-bearing mice
    • Takakura, Y., Fujita, T., Hashida, M., and Sezaki, H. 1990. Disposition characteristics of macromolecules in tumor-bearing mice. Pharm. Res. 7:339-346.
    • (1990) Pharm. Res. , vol.7 , pp. 339-346
    • Takakura, Y.1    Fujita, T.2    Hashida, M.3    Sezaki, H.4
  • 143
    • 0028833556 scopus 로고
    • Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs
    • Takakura, Y., and Hashida, M. 1994. Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs. Crit. Rev. Oncol. Hematol. 18:207-231.
    • (1994) Crit. Rev. Oncol. Hematol. , vol.18 , pp. 207-231
    • Takakura, Y.1    Hashida, M.2
  • 144
    • 0026185431 scopus 로고
    • Properties of mitomycin C-protein conjugates in vitro and in vivo
    • Tanaka, T., Kaneo, Y., and Iguchi, S. 1991. Properties of mitomycin C-protein conjugates in vitro and in vivo. Bioconjugate Chem. 2:261-269.
    • (1991) Bioconjugate Chem. , vol.2 , pp. 261-269
    • Tanaka, T.1    Kaneo, Y.2    Iguchi, S.3
  • 145
    • 0029974294 scopus 로고    scopus 로고
    • Synthesis of transferrin-mitomycin C conjugate as a receptor-mediated drug targeting system
    • Tanaka, T., Kaneo, Y., and Miyashita, M. 1996. Synthesis of transferrin-mitomycin C conjugate as a receptor-mediated drug targeting system. Biol. Pharm. Bull. 19:774-777.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 774-777
    • Tanaka, T.1    Kaneo, Y.2    Miyashita, M.3
  • 146
    • 0027771378 scopus 로고
    • The disposition of serum proteins as drug carriers in mice bearing sarcoma 180
    • Tanaka, T., Kaneo, Y., Shiramoto, S., and Iguchi, S. 1993. The disposition of serum proteins as drug carriers in mice bearing sarcoma 180. Biol. Pharm. Bull. 16:1270-1275.
    • (1993) Biol. Pharm. Bull. , vol.16 , pp. 1270-1275
    • Tanaka, T.1    Kaneo, Y.2    Shiramoto, S.3    Iguchi, S.4
  • 148
    • 0006052482 scopus 로고
    • A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolaseed, as required for a lysosomotropic drug carrier conjugate: In vitro and in vivo studies
    • Trouet, A., Masquelier, M., Baurain, R., and Campeneere, D. D.-D. 1982. A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolaseed, as required for a lysosomotropic drug carrier conjugate: In vitro and in vivo studies. Proc. Natl. Acad. Sci. USA 79:626-629.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 626-629
    • Trouet, A.1    Masquelier, M.2    Baurain, R.3    Campeneere, D.D.-D.4
  • 149
    • 0023701518 scopus 로고
    • Transferrin receptor as a potential therapeutic agent
    • Trowbridge, I. S. 1988. Transferrin receptor as a potential therapeutic agent. Prog. Allergy 45:121-146.
    • (1988) Prog. Allergy , vol.45 , pp. 121-146
    • Trowbridge, I.S.1
  • 150
    • 0019570604 scopus 로고
    • Human cell surface glycoprotein related to the cell proliferation is the receptor for transfenin
    • Trowbridge, I. S., and Omary, M. B. 1981. Human cell surface glycoprotein related to the cell proliferation is the receptor for transfenin. Proc. Natl. Acad. Sci. USA 78:3039-3043.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3039-3043
    • Trowbridge, I.S.1    Omary, M.B.2
  • 151
    • 0024676055 scopus 로고
    • Targeting effect of transferrin-neocarzinostatin conjugate by receptor-mediated endocytosis
    • Urushizaki, I. 1989. Targeting effect of transferrin-neocarzinostatin conjugate by receptor-mediated endocytosis. Nippon Rinsho - Japan. J. Clin. Med. 47: 1423-1431.
    • (1989) Nippon Rinsho - Japan. J. Clin. Med. , vol.47 , pp. 1423-1431
    • Urushizaki, I.1
  • 152
    • 0029782318 scopus 로고    scopus 로고
    • Receptor-mediated uptake of low-density lipoprotein by B16 melanoma cells in vitro and in vivo in mice
    • Versluis, A. J., van Geel, P. J., Oppelaar, H., van Berkél, T. J. C., and Bijsterbosch, M. K. 1996. Receptor-mediated uptake of low-density lipoprotein by B16 melanoma cells in vitro and in vivo in mice. Br. J. Cancer 74:525-532.
    • (1996) Br. J. Cancer , vol.74 , pp. 525-532
    • Versluis, A.J.1    Van Geel, P.J.2    Oppelaar, H.3    Van Berkél, T.J.C.4    Bijsterbosch, M.K.5
  • 153
    • 0026334064 scopus 로고
    • Uptake of low-density lipoprotein by malignant cells - Possible therapeutic applications
    • Vitols, S. 1991. Uptake of low-density lipoprotein by malignant cells - possible therapeutic applications. Cancer Cells 3:488-495.
    • (1991) Cancer Cells , vol.3 , pp. 488-495
    • Vitols, S.1
  • 154
    • 0021260784 scopus 로고
    • Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation
    • Vitols, S., Gahrton, G., Öst, Å., and Peterson, C. 1984. Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation. Blood 63:1186-1193.
    • (1984) Blood , vol.63 , pp. 1186-1193
    • Vitols, S.1    Gahrton, G.2    Öst, Å.3    Peterson, C.4
  • 155
    • 0025084549 scopus 로고
    • Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. in vitro and in vivo studies of a drug-lipoprotein complex
    • Vitols, S., Söderberg-Reid, K., Masquelier, M., Sjöström, B., and Peterson, C. 1990. Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo studies of a drug-lipoprotein complex. Br. J. Cancer 62:724-729.
    • (1990) Br. J. Cancer , vol.62 , pp. 724-729
    • Vitols, S.1    Söderberg-Reid, K.2    Masquelier, M.3    Sjöström, B.4    Peterson, C.5
  • 156
    • 0028416238 scopus 로고
    • Delivery of drugs, proteins and genes into cells using transferrin as ligand for receptor-mediated endocytosis
    • Wagner, E., Curiel, D., and Cotten, M. 1994. Delivery of drugs, proteins and genes into cells using transferrin as ligand for receptor-mediated endocytosis. Adv. Drug Del. Rev. 14:113-135.
    • (1994) Adv. Drug Del. Rev. , vol.14 , pp. 113-135
    • Wagner, E.1    Curiel, D.2    Cotten, M.3
  • 157
    • 26744463431 scopus 로고
    • Apo B-lecithin-cholesterol ester complexes: Reassembly of low density lipoprotein
    • Walsh, M. T., Ginsburg, G. S., Small, D. M., and Atkinson, D. 1982. Apo B-lecithin-cholesterol ester complexes: Reassembly of low density lipoprotein. Arteriosclerosis 2:445a.
    • (1982) Arteriosclerosis , vol.2
    • Walsh, M.T.1    Ginsburg, G.S.2    Small, D.M.3    Atkinson, D.4
  • 158
    • 0041118635 scopus 로고
    • Anti-tumor activity of the main-group metallic elements: Aluminium, gallium, thallium, germanium, lead, antimony and bismuth
    • Chapter 1. ed. M. F. Gielen, London: Freund Publishing House Ltd.
    • Ward, S. G., and Taylor, R. C. 1988. Anti-tumor activity of the main-group metallic elements: Aluminium, gallium, thallium, germanium, lead, antimony and bismuth. In Metal-based Antitumor Drugs, Chapter 1. ed. M. F. Gielen, London: Freund Publishing House Ltd.
    • (1988) Metal-based Antitumor Drugs
    • Ward, S.G.1    Taylor, R.C.2
  • 159
    • 0017377435 scopus 로고
    • Response to transferrin bound iron to treatment of rat lymphosarcoma with cisdichlorodiammine-platinum(II)
    • Warner, F. W., Demanuelle, M., Stjemholm, R., Cohn, I., and Baddley, W. H. 1977. Response to transferrin bound iron to treatment of rat lymphosarcoma with cisdichlorodiammine-platinum(II). J. Clin. Hematol. Oncol. 7:180-189.
    • (1977) J. Clin. Hematol. Oncol. , vol.7 , pp. 180-189
    • Warner, F.W.1    Demanuelle, M.2    Stjemholm, R.3    Cohn, I.4    Baddley, W.H.5
  • 160
    • 0025005475 scopus 로고
    • Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: Evidence for synergistic antiproliferative effects
    • White, S., Taetle, R., Seligman, P. A., Rutherford, M., and Trowbridge, I. S. 1991. Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: Evidence for synergistic antiproliferative effects. Cancer Res. 50:6295-6301.
    • (1991) Cancer Res. , vol.50 , pp. 6295-6301
    • White, S.1    Taetle, R.2    Seligman, P.A.3    Rutherford, M.4    Trowbridge, I.S.5
  • 162
    • 0021257795 scopus 로고
    • Killing of human tumor cells in culture with adriamycin conjugates of human transferrin
    • Yeh, C. J., and Faulk, W. P. 1984. Killing of human tumor cells in culture with adriamycin conjugates of human transferrin. Clin. Immunol. Immunopath. 32:1-11.
    • (1984) Clin. Immunol. Immunopath. , vol.32 , pp. 1-11
    • Yeh, C.J.1    Faulk, W.P.2
  • 163
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
    • Yuan, F., Deilian, M., Fukumura, D., Leuning, M., Berk, D. A., Torchilin. V. P., and Jain, R. K. 1995. Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size. Cancer Res. 55:3752-3756.
    • (1995) Cancer Res. , vol.55 , pp. 3752-3756
    • Yuan, F.1    Deilian, M.2    Fukumura, D.3    Leuning, M.4    Berk, D.A.5    Torchilin, V.P.6    Jain, R.K.7
  • 164
    • 0025219193 scopus 로고
    • The relation between hypocholesterolemia and degree of maturation of in acute myeloid leukemia
    • Zyada, L. E., Hassan, H. T., Rees, J. K. H., and Ragab, M. H. 1990. The relation between hypocholesterolemia and degree of maturation of in acute myeloid leukemia. Hematol. Oncol. 8:65-69.
    • (1990) Hematol. Oncol. , vol.8 , pp. 65-69
    • Zyada, L.E.1    Hassan, H.T.2    Rees, J.K.H.3    Ragab, M.H.4


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