Ongoing somatic mutations and clonal expansions after cure of Helicobacter pylori infection in gastric mucosa-assiociated lymphoid tissue B-cell lymphoma

Journal of Clinical Oncology

Volumn 16, Issue 12, 1998, Pages 3822-3831

  Thiede, Christian ^a   Alpen, Birgit ^a   Morgner, Andrea ^a   Schmidt, Manuel ^a   Ritter, Markus ^a   Ehninger, Gerhard ^a   Stolte, Manfred ^a   Bayerdörffer, Ekkehard ^a   Neubauer, Andreas ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; IMMUNOGLOBULIN HEAVY CHAIN; OMEPRAZOLE;

ARTICLE; B CELL LYMPHOMA; CANCER GENETICS; CLINICAL ARTICLE; DNA SEQUENCE; FOLLOW UP; GENE MUTATION; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOGENETICS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR CLONING; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PRIORITY JOURNAL;

EID: 0032406881     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.12.3822     Document Type: Article

References (50)

1. Isaacson PG, Wright DH: Malignant lymphoma of mucosaassociated lymphoid tissue. A distinctive type of B-cell lymphoma. Cancer 52:1410-1416, 1983
2. Harris NL, Jaffe ES, Stein H, et al: A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361-1392, 1994
3. Stolte M, Eidt S: Lymphoid follicles in antral mucosa: Immune response to Campylobacter pylori. J Clin Pathol 42:1269-1271, 1989
4. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, et al: Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 338:1175-1176, 1991
5. Eidt S, Stolte M: Prevalence of lymphoid follicles and aggregates in Helicobacter pylori gastritis in antral and body mucosa. J Clin Pathol 46:832-835, 1993
6. Wotherspoon AC, Doglioni C, Diss TC, et al: Regression of primary low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342:575-577, 1993
7. Bayerdörffer E, Neubauer A, Rudolph B, et al: Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet 345:1591-1594, 1995
8. Roggero E, Zucca E, Pinotti G, et al: Eradication of Helicobacter pylori infection in primary low-grade lymphoma of the mucosaassociated lymphoid tissue. Ann Intern Med 122:767-769, 1995
9. Nakamura S, Akazawa K, Kinukawa N, et al: Inverse correlation between the expression of bcl-2 and p53 proteins in primary gastric lymphoma. Hum Pathol 27:225-233, 1996
10. Pan L, Diss TC, Cunningham D: The bcl-2 gene in primary B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). Am J Pathol 135:7-11, 1989
11. Wotherspoon AC, Pan LX, Diss TC: A genotypic study of low-grade B-cell lymphomas, including lymphomas of the mucosa associated lymphoid tissue (MALT). J Pathol 162:135-140, 1990
12. Rajewsky K: Clonal selection and learning in the antibody system. Nature 381:751-758, 1996
13. H5 genes used in common B-cell chronic lymphocytic leukemia. J Exp Med 177:1039-1046, 1993
14. Hummel M, Tamara J, Kalvelage B: Mantle cell (previously centrocytic) lymphomas express VH genes with no or very little somatic mutations like the physiologic cells of the follicle mantle. Blood 84:403-407, 1994
15. Zelenetz AD, Chen TT, Levy R: Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection. J Exp Med 176:1137-1148, 1992
16. Zhu D, Hawkins RE, Hamblin TJ, et al: Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes. Br J Haematol 86:505-512, 1994
17. H genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity. Blood 85:2176-2181, 1995
18. L gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection. Blood 88:3562-3568, 1996
19. Kanzler H, Kuppers R, Hansmann ML, et al: Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. J Exp Med 184:1495-1505, 1996
20. Qin Y, Greiner A, Trunk MJF. et al: Somatic hypermutation in low-grade mucosa associated lymphoid tissue-type B-cell lymphoma. Blood 86:3528-3534, 1995
21. Du M, Diss TC, Peng H, et al: Ongoing mutation in MALT lymphoma immunoglobulin gene suggests that antigen stimulation plays a role in the clonal expansion. Leukemia 10:1190-1197, 1996
22. Du M, Xu C, Diss TC, et al: Intestinal dissemination of gastric mucosa associated lymphoid tissue lymphoma. Blood 88:4445-4451, 1996
23. Qin Y, Greiner A, Hallas C, et al: Intraclonal offspring expansion of gastric low-grade MALT-type lymphoma: Evidence for the role of antigen driven high affinity mutation in lymphomagenesis. Lab Invest 76:477-485, 1997
24. Bahler DW, Miklos JA, Swerdlow SH: Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas. Blood 89:3335-3344, 1997
25. Neubauer A, Thiede C, Morgner A, et al: Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa associated lymphoid tissue lymphoma. J Natl Cancer Inst 89:1350-1355, 1997
26. Isaacson PG: Gastrointestinal lymphomas. Hum Pathol 25:1020-1029, 1994
27. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning - A Laboratory Manual (ed 2). New York, NY, Cold Spring Harbor Laboratory Press, 1989
28. Diss TC, Peng H, Wotherspoon AC, et al: Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 169:291-295, 1993
29. Aubin J. Davi F, Nguyen-Salomon F, et al: Description of a novel FR1 IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B cell malignancies. Leukemia 9:471-479, 1995
30. Giudicelli V, Chaume D, Bodmer J, et al: IMGT. the international ImMunoGeneTics database. Nucleic Acids Res 25:206-211, 1997
31. Corbett SJ, Tomlinson IA, Sonnhammer ELL, et al: Sequence of the human immunoglobulin diversity (D) segment locus: A systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination. J Mol Biol 270:587-597, 1997
32. H genes are inherently susceptible to amino acid replacement. Immunol Today 15:367-373, 1994
33. Shlomchik MJ, Aucoin AH, Pisetsky DS, et al: Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. Proc Nati Acad Sci U S A 84:9150-9154. 1987
34. Efremov DG, Ivanowski M, Siljanowski N, et al: Restricted immunoglobulin VH repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia. Blood 87:3869-3876, 1996
35. Borretzen M, Randen I, Natvig JB, et al: Structural restriction in the heavy chain CDR3 of human rheumatoid factors. J Immunol 155:3630-3637, 1995
36. Sanz I, Wang SS, Meneses G. et al: Molecular characterization of human Ig heavy chain DIR genes. J Immunol 152:3958-3969, 1994
37. Saiki RK, Gelfand DH, Stoffel S, et al: Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487-491, 1988
38. Hyjek E, Isaacson PG: Primary B cell lymphoma of the thyroid and its relationship to Hashimoto's thyroiditis. Hum Pathol 19:1315-1326, 1988
39. Diss TC, Wotherspoon AC, Speight P, et al: B-cell monoclonality, Epstein-Barr virus, and t(14;18) in myoepithelial sialadenitis and low-grade B-cell MALT lymphoma of the parotid gland. Am J Surg Pathol 19:531-536, 1995
40. Bahler DW, Levy R: Clonal evolution of a follicular lymphoma: Evidence for antigen selection. Proc Natl Acad Sci USA 89:6770-6774. 1992
41. Hussell T, Isaacson PG, Crabtree JE, et al: Immunoglobulin specificity of low-grade B-cell gastrointestinal lymphoma of the mucosa-associated lymphoid tissue (MALT) type. Am J Pathol 142:285-292, 1993
42. Hussell T, Isaacson PG, Crabtree JE, et al: Helicobacler pylorispecific tumour infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of the mucosa-associated lymphoid tissue. J Pathol 178:122-127, 1996
43. Negrini R, Lisato L, Zanella I, et al: Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology 101:437-445, 1991
44. Greiner A, Vollmers HP, Müller-Hermelink HK: Autoantikörper eines IgA-exprimierenden mucosa-assoziierten Magenlymphoms. Verh Dtsch Ges Path 76:314, 1992
45. Sorrentino D, Ferraccioli G, Devita S, et al: Gastric B-cell clonal expansion and Helicobacter pylori infection in patients with autoimmune diseases and with dyspepsia. A follow-up study. Scand J Gastroenterol 32:1204-1208, 1997
46. Savio A, Franzin G, Wotherspoon AC, et al: Diagnosis and posttreatment follow up of Helicobacter pylori-positive gastric lymphoma of mucosa-associated lymphoid tissue: Histology, polymerase chain reaction, or both? Blood 87:1255-1260, 1996
47. Rudolph B, Bayerdörffer E, Ritter M, et al: Is the polymerase chain reaction or cure of Helicobacter pylori infection of help in the differential diagnosis of early gastric mucosa-associated lymphatic tissue lymphoma? J Clin Oncol 15:1104-1109, 1997
48. Zucca E, Bertoni F, Roggero E, et al: Molecular analysis of the progression from Helicobacter pylori-associated chronic gastritis to mucosa associated lymphoid tissue lymphoma of the stomach. N Engl J Med 338:804-810, 1998
49. Wotherspoon AC, Finn TM, Isaacson PG: Trisomy 3 in low grade B cell lymphomas of mucosa associated lymphoid tissue. Blood 85:2000-2004, 1995
50. Ott G, Katzenberger T, Greiner A, et al: The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT)-type. Cancer Res 57:3944-3948, 1997