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Volumn 70, Issue 6, 1998, Pages 1090-1100

Abnormalities in the serum insulin-like growth factor-1 axis in women with hyperandrogenism

Author keywords

Adrenal; Functional androgen excess; Growth hormone; Hirsutism; Hyperandrogenism; Insulin like growth factor 1; Insulin like growth factor binding protein 3; Ovary

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; CORTICOTROPIN; CORTODOXONE; CYTOCHROME P450 ISOENZYME; ESTRADIOL; FOLLITROPIN; GLUCOSE; GONADORELIN; GONADOTROPIN; GROWTH HORMONE; HYDROCORTISONE; HYDROXYPROGESTERONE; INSULIN; LUTEINIZING HORMONE; PRASTERONE SULFATE; PROGESTERONE; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TESTOSTERONE; TETRACOSACTIDE; TRIPTORELIN;

EID: 0032403591     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(98)00388-4     Document Type: Article
Times cited : (20)

References (28)
  • 2
    • 0028133098 scopus 로고
    • Ovarian suppression with triptorelin and adrenal stimulation with adrenocorticotropin in functional hyperandrogenism: Role of adrenal and ovarian cytochrome P450c17 alpha
    • Escobar-Morreale H., Pazos F., Potau N., García-Robles R., Sancho J.M., Varela C. Ovarian suppression with triptorelin and adrenal stimulation with adrenocorticotropin in functional hyperandrogenism role of adrenal and ovarian cytochrome P450c17 alpha . Fertil Steril. 62:1994;521-530.
    • (1994) Fertil Steril , vol.62 , pp. 521-530
    • Escobar-Morreale, H.1    Pazos, F.2    Potau, N.3    García-Robles, R.4    Sancho, J.M.5    Varela, C.6
  • 3
    • 0343683374 scopus 로고    scopus 로고
    • Lack of an ovarian function influence on the increased adrenal androgen secretion present in women with functional ovarian hyperandrogenism
    • Escobar-Morreale H.F., Serrano-Gotarredona J., García-Robles R., Sancho J., Varela C. Lack of an ovarian function influence on the increased adrenal androgen secretion present in women with functional ovarian hyperandrogenism. Fertil Steril. 67:1997;654-662.
    • (1997) Fertil Steril , vol.67 , pp. 654-662
    • Escobar-Morreale, H.F.1    Serrano-Gotarredona, J.2    García-Robles, R.3    Sancho, J.4    Varela, C.5
  • 4
    • 0030872461 scopus 로고    scopus 로고
    • Mild adrenal and ovarian steroidogenic abnormalities in hirsute women without hyperandrogenemia: Does idiopathic hirsutism exist?
    • Escobar-Morreale H.F., Serrano Gotarredona J., García-Robles R., Sancho J., Varela C. Mild adrenal and ovarian steroidogenic abnormalities in hirsute women without hyperandrogenemia does idiopathic hirsutism exist? Metabolism. 46:1997;902-907.
    • (1997) Metabolism , vol.46 , pp. 902-907
    • Escobar-Morreale, H.F.1    Serrano Gotarredona, J.2    García-Robles, R.3    Sancho, J.4    Varela, C.5
  • 5
    • 85047696604 scopus 로고
    • Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion
    • Ehrmann D.A., Barnes R.B., Rosenfield R.L. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocr Rev. 16:1995;322-353.
    • (1995) Endocr Rev , vol.16 , pp. 322-353
    • Ehrmann, D.A.1    Barnes, R.B.2    Rosenfield, R.L.3
  • 6
    • 0030988978 scopus 로고    scopus 로고
    • Frequency of a polymorphism in the regulatory region of the 17α-hydroxylase (CYP17) gene in hyperandrogenic states
    • Techatraisk K., Conway G.S., Rumsby G. Frequency of a polymorphism in the regulatory region of the 17α-hydroxylase (CYP17) gene in hyperandrogenic states. Clin Endocrinol (Oxf). 46:1997;131-134.
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 131-134
    • Techatraisk, K.1    Conway, G.S.2    Rumsby, G.3
  • 7
    • 0028040909 scopus 로고
    • Identification and cellular localization of growth hormone receptor gene expression in the human ovary
    • Sharara F.I., Nieman L.K. Identification and cellular localization of growth hormone receptor gene expression in the human ovary. J Clin Endocrinol Metab. 79:1994;670-672.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 670-672
    • Sharara, F.I.1    Nieman, L.K.2
  • 8
    • 0024994950 scopus 로고
    • Direct gonadotrophic effect of growth hormone on oestradiol production by human granulosa cells in vitro
    • Mason H.D., Martikainen H., Beard R.W., Anyaoku V., Franks S. Direct gonadotrophic effect of growth hormone on oestradiol production by human granulosa cells in vitro. J Endocrinol. 126:1990;R1-R4.
    • (1990) J Endocrinol , vol.126
    • Mason, H.D.1    Martikainen, H.2    Beard, R.W.3    Anyaoku, V.4    Franks, S.5
  • 9
    • 0027194106 scopus 로고
    • Differentiation of ovarian thecainterstitial cells in vitro: Regulation of 17α-hydroxylase messenger ribonucleic acid expression by luteinizing hormone and insulin-like growth factor-I
    • Magoffin D.A., Weitsman S.R. Differentiation of ovarian thecainterstitial cells in vitro regulation of 17α-hydroxylase messenger ribonucleic acid expression by luteinizing hormone and insulin-like growth factor-I . Endocrinology. 132:1993;1945-1951.
    • (1993) Endocrinology , vol.132 , pp. 1945-1951
    • Magoffin, D.A.1    Weitsman, S.R.2
  • 10
    • 0030918908 scopus 로고    scopus 로고
    • Insulin-like growth factors augment steroid production and expression of steroidogenic enzymes in human fetal adrenal cortical cells: Implications for adrenal androgen regulation
    • Mesiano S., Katz S.L., Lee J.Y., Jaffe R.B. Insulin-like growth factors augment steroid production and expression of steroidogenic enzymes in human fetal adrenal cortical cells implications for adrenal androgen regulation . J Clin Endocrinol Metab. 82:1997;1390-1396.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1390-1396
    • Mesiano, S.1    Katz, S.L.2    Lee, J.Y.3    Jaffe, R.B.4
  • 11
    • 0029818083 scopus 로고    scopus 로고
    • Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells
    • l'Allemand D., Penhoat A., Lebrethon M.C., Ardevol R., Baehr V., Oelkers W., et al. Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells. J Clin Endocrinol Metab. 81:1996;3892-3897.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3892-3897
    • L'Allemand, D.1    Penhoat, A.2    Lebrethon, M.C.3    Ardevol, R.4    Baehr, V.5    Oelkers, W.6
  • 12
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler J.E., Jakubowicz D.J. Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med. 335:1996;617-623.
    • (1996) N Engl J Med , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 13
    • 0026729957 scopus 로고
    • Puberty and polycystic ovarian syndrome: The insulin/insulin-like growth factor I hypothesis
    • Nobels F., Dewailly D. Puberty and polycystic ovarian syndrome the insulin/insulin-like growth factor I hypothesis . Fertil Steril. 58:1992;655-666.
    • (1992) Fertil Steril , vol.58 , pp. 655-666
    • Nobels, F.1    Dewailly, D.2
  • 14
    • 0024997304 scopus 로고
    • An abnormality of the growth hormone/insulin-like growth factor-I axis in women with polycystic ovary syndrome
    • Kazer R.R., Unterman T.G., Glick R.P. An abnormality of the growth hormone/insulin-like growth factor-I axis in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 71:1990;958-962.
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 958-962
    • Kazer, R.R.1    Unterman, T.G.2    Glick, R.P.3
  • 15
    • 0028122326 scopus 로고
    • The response of the growth hormone and insulin-like growth factor I axis to medical castration in women with polycystic ovarian syndrome
    • Hatasaka H.H., Kazer R.R., Chatterton R.T., Unterman T.G., Glick R.P. The response of the growth hormone and insulin-like growth factor I axis to medical castration in women with polycystic ovarian syndrome. Fertil Steril. 62:1994;273-278.
    • (1994) Fertil Steril , vol.62 , pp. 273-278
    • Hatasaka, H.H.1    Kazer, R.R.2    Chatterton, R.T.3    Unterman, T.G.4    Glick, R.P.5
  • 16
    • 0027049876 scopus 로고
    • Twenty-four-hour serum growth hormone, insulin, C-peptide and blood glucose profiles and serum insulin-like growth factor-I concentrations in women with polycystic ovaries
    • Prelevic G.M., Wurzburger M.I., Balint-Peric L., Ginsburg J. Twenty-four-hour serum growth hormone, insulin, C-peptide and blood glucose profiles and serum insulin-like growth factor-I concentrations in women with polycystic ovaries. Horm Res. 37:1992;125-131.
    • (1992) Horm Res , vol.37 , pp. 125-131
    • Prelevic, G.M.1    Wurzburger, M.I.2    Balint-Peric, L.3    Ginsburg, J.4
  • 17
    • 0027173395 scopus 로고
    • Growth hormone response to L-dopa and pyridostigmine in women with polycystic ovarian syndrome
    • Lee E.J., Lee B.S., Lee H.C., Park K.H., Song C.H., Huh K.B. Growth hormone response to L-dopa and pyridostigmine in women with polycystic ovarian syndrome. Fertil Steril. 60:1993;53-57.
    • (1993) Fertil Steril , vol.60 , pp. 53-57
    • Lee, E.J.1    Lee, B.S.2    Lee, H.C.3    Park, K.H.4    Song, C.H.5    Huh, K.B.6
  • 18
    • 0026389630 scopus 로고
    • Interactions between insulin and insulin-like growth factor I in the pathogenesis of polycystic ovarian disease
    • Urdl W., Desoye G., Schmon B., Hofmann H.M., Ralph G. Interactions between insulin and insulin-like growth factor I in the pathogenesis of polycystic ovarian disease. Ann N Y Acad Sci. 626:1991;177-183.
    • (1991) Ann N Y Acad Sci , vol.626 , pp. 177-183
    • Urdl, W.1    Desoye, G.2    Schmon, B.3    Hofmann, H.M.4    Ralph, G.5
  • 20
    • 0031757968 scopus 로고    scopus 로고
    • The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function
    • Escobar-Morreale H.F., Serrano-Gotarredona J., Avila S., Villar-Palasí J., Varela C., Sancho J. The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function. J Clin Endocrinol Metab. 83:1998;2580-2584.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2580-2584
    • Escobar-Morreale, H.F.1    Serrano-Gotarredona, J.2    Avila, S.3    Villar-Palasí, J.4    Varela, C.5    Sancho, J.6
  • 21
    • 0030802948 scopus 로고    scopus 로고
    • Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche
    • Ibáñez L., Potau N., Zampolli M., Riqué S., Saenger P., Carrascosa A. Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche. J Clin Endocrinol Metab. 82:1997;2283-2288.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2283-2288
    • Ibáñez, L.1    Potau, N.2    Zampolli, M.3    Riqué, S.4    Saenger, P.5    Carrascosa, A.6
  • 22
    • 0028822412 scopus 로고
    • Growth hormone, insulin-like growth factor-I axis, and insulin secretion in hyperandrogenic adolescents
    • Ibáñez L., Potau N., Georgopoulos N., Prat N., Gussinyé M., Carrascosa A. Growth hormone, insulin-like growth factor-I axis, and insulin secretion in hyperandrogenic adolescents. Fertil Steril. 64:1995;1113-1119.
    • (1995) Fertil Steril , vol.64 , pp. 1113-1119
    • Ibáñez, L.1    Potau, N.2    Georgopoulos, N.3    Prat, N.4    Gussinyé, M.5    Carrascosa, A.6
  • 23
    • 0027166906 scopus 로고
    • Postpubertal outcome in girls diagnosed of premature pubarche during childhood: Increased frequency of functional ovarian hyperandrogenism
    • Ibáñez L., Potau N., Virdis R., Zampolli M., Terzi C., Gussinyé M., et al. Postpubertal outcome in girls diagnosed of premature pubarche during childhood increased frequency of functional ovarian hyperandrogenism . J Clin Endocrinol Metab. 76:1993;1599-1603.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1599-1603
    • Ibáñez, L.1    Potau, N.2    Virdis, R.3    Zampolli, M.4    Terzi, C.5    Gussinyé, M.6
  • 24
    • 0029833087 scopus 로고    scopus 로고
    • Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: Common and distinct features
    • Morales A.J., Laughlin G.A., Butzow T., Maheshwari H., Baumann G., Yen S.S. Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome common and distinct features . J Clin Endocrinol Metab. 81:1996;2854-2864.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2854-2864
    • Morales, A.J.1    Laughlin, G.A.2    Butzow, T.3    Maheshwari, H.4    Baumann, G.5    Yen, S.S.6
  • 25
    • 0028607478 scopus 로고
    • Regulation of extragonadal insulin-like growth factor-binding protein-3 by testosterone in oophorectomized women
    • Azziz R., Deal C.L., Potter H.D., Gargosky S.E., Rosenfeld R.G. Regulation of extragonadal insulin-like growth factor-binding protein-3 by testosterone in oophorectomized women. J Clin Endocrinol Metab. 79:1994;1747-1751.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1747-1751
    • Azziz, R.1    Deal, C.L.2    Potter, H.D.3    Gargosky, S.E.4    Rosenfeld, R.G.5
  • 26
    • 0031912373 scopus 로고    scopus 로고
    • Development of hyperandrogenism during treatment with insulin-like growth factor-I (IGF-I) in female patients with Laron syndrome
    • Klinger B., Anin S., Silbergeld A., Eshet R., Laron Z. Development of hyperandrogenism during treatment with insulin-like growth factor-I (IGF-I) in female patients with Laron syndrome. Clin Endocrinol (Oxf). 48:1998;81-87.
    • (1998) Clin Endocrinol (Oxf) , vol.48 , pp. 81-87
    • Klinger, B.1    Anin, S.2    Silbergeld, A.3    Eshet, R.4    Laron, Z.5
  • 27
    • 0029831597 scopus 로고    scopus 로고
    • Growth hormones and sex steroid interactions at puberty
    • Clark P.A., Rogol A.D. Growth hormones and sex steroid interactions at puberty. Endocrinol Metab Clin North Am. 25:1996;665-681.
    • (1996) Endocrinol Metab Clin North Am , vol.25 , pp. 665-681
    • Clark, P.A.1    Rogol, A.D.2


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