The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 7, 1998, Pages 2580-2584

  Escobar Morreale, Héctor F ^a   Serrano Gotarredona, Joaquín ^b   Avila, Sergio ^a   Villar Palasí, Juan ^a   Varela, César ^c   Sancho, José ^c  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE   (Spain)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; TRIPTORELIN;

ADRENAL FUNCTION; ANTIGEN DETECTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DISEASE MARKER; FEMALE; FOLLICULAR PHASE; HIRSUTISM; HORMONE BLOOD LEVEL; HUMAN; HYPERANDROGENISM; OVARY FUNCTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; STATISTICAL ANALYSIS;

EID: 0031757968     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.7.4960     Document Type: Review

References (19)

1. Diamandis EF. 1996 Prostate specific antigen-new applications in breast and other cancers. Anticancer Res. 16:3983-3984.
2. Diamandis EP, Yu H. 1997 Nonprostatic sources of prostate-specific antigen. Urol Clin North Am. 24:275-282.
3. Giai M, Yu H, Roagna R, et al. 1995 Prostate-specific antigen in serum of women with breast cancer. Br J Cancer. 72:728-731.
4. Borchert GH, Giai M, Diamandis EP. 1997 Elevated levels of prostate-specific antigen in serum of women with fibroadenomas and breast cysts. J Natl Cancer Inst. 89:587-588.
5. Melegos DN, Yu H, Ashok M, Wang C, Stanczyk F, Diamandis EP. 1997 Prostate-specific antigen in female serum, a potential new marker of androgen excess. J Clin Endocrinol Metab. 82:777-780.
6. Escobar-Morreale H, Pazos F, Potau N, Garcia Robles R, Sancho JM, Varela C. 1994 Ovarian suppression with triptorelin and adrenal stimulation with adrenocorticotropin in functional hyperadrogenism: role of adrenal and ovarian cytochrome P450c17 alpha. Fertil Steril. 62:521-530.
7. Ferriman D, Gallwey JD. 1961 Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 21:1440-1447.
8. Escobar-Morreale HF, Serrano Gotarredona J, García Robles R, Sancho J, Varela C. 1997 Mild adrenal and ovarian steroidogenic abnormalities in hirsute women without hyperandrogenemia: does idiopathic hirsutism exist? Metabolism. 46:902-907.
9. Escobar-Morreale HF, Serrano-Gotarredona J, García-Robles R, Sancho J, Varela C. 1997 Lack of an ovarian function influence on the increased adrenal androgen secretion present in women with functional ovarian hyperandrogenism. Fertil Steril. 67:654-662.
10. Escobar-Morreale HF, Serrano-Gotarredona J, Varela C, García-Robles R, Sancho JM. 1997 Circulating leptin concentrations in women with hirsutism. Fertil Steril. 68:898-906.
11. Castelo Branco C, Martinez de Osaba MJ, Martinez S, Fortuny A. 1996 Effects of a long-acting gonadotropin-releasing hormone analog on the pituitary-ovarian-adrenal axis in women with severe hirsutism. Metabolism. 45:24-27.
12. Witherspoon LR, Lapeyrolerie T. 1997 Sensitive prostate specific antigen measurements identify men with long disease-free intervals and differentiate aggressive from indolent cancer recurrences within 2 years after radical prostatectomy. j Urol. 157:1322-1328.
13. Adams J, Poison DW, Abdulwahid N, et al. 1985 Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone. Lancet. 2:1375-1379.
14. Dawson-Saunders B, Trapp RG. 1990 Basic and clinical bioestatistics. East Norwalk: Appleton and Lange.
15. Diamandis EP, Yu H, Melegos DN. 1996 Ultrasensitive prostate specific antigen assays and their clinical application. Clin Chem. 42:853-857.
16. Ferguson RA, Yu H, Kalyvas M, Zammit S, Diamandis EP. 1996 Ultrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite® immunochemiluminiscent third generation assay: potential applications in prostate and breast cancer. Clin Chem. 42:675-684.
17. Zarghami N, Grass L, Sauter ER, Diamandis EP. 1997 Prostate-specific antigen in serum during the menstrual cycle. Clin Chem. 43:1862-1867.
18. Tepper SL, Jagirdar J, Heath D, Geller SA. 1984 Homology between the female paraurethral (Skene's) glands and the prostate. Immunohistochemical demonstration. Arch Pathol Lab Med. 108:423-425.
19. Dodson MK, Cliby WA, Keeney GL, Peterson MF, Podratz KC. 1994 Skene's gland adenocarcinoma with increased serum level of prostate-specific antigen. Gynecol Oncol. 55:304-307.