The antiestrogen tamoxifen blocks the delayed rectifier potassium current, IKP in rabbit ventricular myocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 287, Issue 3, 1998, Pages 877-883

  Liu, Xiao K E ^a   Katchman, Alexander ^a   Ebert, Steven N ^a   Woosley, Raymond L ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; POTASSIUM ION; TAMOXIFEN; 1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; ANTIESTROGEN; PIPERIDINE DERIVATIVE; POTASSIUM; POTASSIUM CHANNEL; PYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART VENTRICLE WALL; NONHUMAN; PATCH CLAMP; PHARMACOLOGICAL BLOCKING; POTASSIUM CURRENT; PRIORITY JOURNAL; QT INTERVAL; RABBIT; TORSADE DES POINTES; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; HEART MUSCLE; HEART VENTRICLE; METABOLISM; TIME;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN ANTAGONISTS; HEART VENTRICLES; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; PIPERIDINES; POTASSIUM; POTASSIUM CHANNELS; PYRIDINES; RABBITS; TAMOXIFEN; TIME FACTORS; TORSADES DE POINTES;

EID: 0032238699     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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