The effects of dietary lipids on gene expression and apoptosis

Proceedings of the Nutrition Society

Volumn 57, Issue 4, 1998, Pages 543-550

  Fernandes, Gabriel ^a   Troyer, Dean A ^b   Jolly, Christopher A ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; UNSATURATED FATTY ACID;

ANIMAL; APOPTOSIS; AUTOIMMUNITY; FAT INTAKE; GENE EXPRESSION; HUMAN; IMMUNITY; REVIEW;

ANIMALS; APOPTOSIS; AUTOIMMUNITY; DIETARY FATS; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; GENE EXPRESSION; HUMANS; IMMUNITY;

EID: 0032200001     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS19980080     Document Type: Article

References (60)

1. Abbas AK, Lichtman AH & Pober JS (1991) Molecular basis of T cell antigen recognition and activation. In Cellular and Molecular Immunology, pp. 139-167 [MJ Wonsiewicz, editor]. Philadelphia, PA: WB Saunders Company.
2. Ahmed AA & Holub BJ (1984) Alteration and recovery of bleeding times, platelet aggregation and fatty acid composition of individual phospholipids in platelets of human subjects receiving a supplement of cod-liver oil. Lipids 19, 617-624.
3. Aringer M, Winterersberger W, Steiner CW, Kiener H, Preseterl E, Jaeger U, Smolen JS & Graninger WB (1994) High levels of bcl-2 protein in circulating T lymphocytes, but not B lymphocytes, of patients with systemic lupus erythematosus. Arthritis and Rheumatism 37, 1423-1430.
4. Bechoua S, Dubois M, Nemoz G, Lagarde M & Prigent AF (1998) Docosahexaenoic acid lowers phosphatidate levels in human activated lymphocytes despite phospholipase D activation. Journal of Lipid Research 39, 873-883.
5. Bursch W, Oberhammer F, Jirtle RL, Askari M, Sedivy R, Grasl-Kraupp B, Purchio AF & Schulte-Hermann R (1993) Transforming growth factor-beta 1 as a signal for induction of cell death by apoptosis. British Journal of Cancer 67, 531-536.
6. Calder PC (1995) Fatty acids, dietary lipids and lymphocyte functions. Biochemical Society Transactions 23, 302-309.
7. Calder PC (1996) Immunomodulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Proceedings of the Nutrition Society 55, 737-774.
8. Calder PC (1997a) N-3 polyunsaturated fatty acids and cytokine production in health and disease. Annals of Nutrition and Metabolism 41, 203-234.
9. Calder PC (1997b) N-3 polyunsaturated fatty acids and immune cell function. Advances in Enzyme Regulation 37, 197-237.
10. Calder PC (1998) Dietary fatty acids and the immune system. Nutrition Reviews 56, S70-S83.
11. Chandrasekar B & Fernandes G (1994) Decreased proinflammatory cytokines and increased antioxidant enzyme gene expression by ω-3 lipids in murine lupus nephritis. Biochemical and Biophysical Research Communications 200, 893-898.
12. Chandrasekar B, McGuff HS, Aufdermorte TB, Troyer DA, Talal N & Fernandes G (1995a) Effects of calorie restriction on transforming growth factor 1 and proinflammatory cytokines in murine Sjogren's syndrome. Clinical Immunology and Immunopathology 76, 291-296.
13. Chandrasekar B, Troyer DA, Venkatraman JT & Fernandes G (1995b) Dietary omega-3 lipids delay the onset and progression of autoimmune lupus nephritis by inhibiting transforming growth factorβ mRNA and protein expression. Journal of Autoimmunity 8, 381-393.
14. Chapkin RS, McMurray DN & Jolly CA (1998) Dietary n-3 polyunsaturated fatty acids modulate T-lymphocyte activation: Clinical relevance in treating diseases of chronic inflammation. In Nutrition Immunology: Principles and Practice (In the Press).
15. Clarke SD & Jump DB (1996) Polyunsaturated fatty acid regulation of hepatic gene transcription. Lipids 31, S7-S11.
16. Clarke SD, Turini M & Jump D (1997) Polyunsaturated fatty acids regulate lipogenic and peroxisomal gene expression by independent mechanisms. Prostaglandins, Leukotrienes and Essential Fatty Acids 57, 65-69.
17. DeCaterina R, Caprioli R, Giannessi D, Sicari R, Galli C, Lazzarini G, Bernini W, Carr L & Rindi P (1993) N-3 fatty acids reduced proteinuria in patients with chronic glomerulonephritis. Kidney International 49, 603-607.
18. DeCaterina R, Endres S, Kristensen SD & Schmidt EB (1994) N-3 fatty acids and renal disease. American Journal of Kidney Disease 24, 397-415.
19. Donadio JVJ, Bergstralh EJ, Offord KP, Spencer DC & Holley KE (1994) A controlled trial of fish oil in IgA nephropathy. Mayo Nephrology Collaborative Group. New England Journal of Medicine 331, 1194-1199.
20. Emlen W, Niebur J & Kadera R (1994) Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. Journal of Immunology 152, 3685-3692.
21. Endres S, Meydani SN, Ghorbani R, Schindler R & Dinarello CA (1993) Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation. Journal of Leukocyte Biology 54, 599-603.
22. Fernandes G (1994) Dietary lipids and risk of autoimmune disease. Clinical Immunology and Immunopathology 72, 193-197.
23. Fernandes G, Chandrasekar B, Luan X & Troyer DA (1996a) Modulation of antioxidant enzymes and programmed cell death by n-3 fatty acids. Lipids 31, S91-S96.
24. Fernandes G, Chandrasekar B, Mountz JD & Zhao W (1995) Modulation of Fas apoptotic gene expression in spleens of B/W mice by the source of dietary lipids with and without calorie restriction. FASEB Journal 9, A787.
25. Fernandes G & Jolly CA (1998) Nutrition and autoimmune disease. Nutrition Reviews 56, S161-S169.
26. Fernandes, G & Venkatraman J (1993) Role of ω-fatty acids in health and disease. Nutrition Research 13, S19-S45.
27. Fernandes G, Venkatraman J & Troyer DA (1996b) Interaction of vitamin E with n-6 and n-3 polyunsaturated fatty acids. International Society for the Study of Fatty Acids and Lipids 3, 10-13.
28. Fritsche KL & Johnston PV (1990) Effect of dietary α-linolenic acid on growth metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas. Nutrition Research 10, 577-588.
29. Gentile MG, Fellin G, Cofano F, Delle Fave A, Mannan G, Iciceri R, Petrini C, Lavarda F, Pozzi F & D'Amico G (1993) Treatment of proteinuric patients with a vegetarian soy diet and fish oil. Clinical Nephrology 40, 315-320.
30. Gomez-Munoz A (1998) Modulation of cell signalling by ceramides. Biochimica et Biophysica Acta 1391, 92-109.
31. Hosack-Fowler K, Chapkin RS & McMurray DN (1993a) Effects of purified dietary n-3 ethyl esters on murine T lymphocyte function. Journal of Immunology 151, 5186-5197.
32. Hosack-Fowler K, McMurray DN, Fan YY, Aukema HM & Chapkin RS (1993b) Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes. Biochimica et Biophysica Acta 1210, 89-96.
33. Hughes DA & Pinder AC (1997) N-3 polyunsaturated fatty acids modulate the expression of functionally associated molecules on human monocytes and inhibit antigen presentation in vitro. Clinical and Experimental Immunology 110, 516-523.
34. Illera V, Perandones CE, Stunz LL, Mower DA & Ashman RF (1993) Apoptosis in splenic B lymphocytes. Journal of Immunology 151, 2965-2973.
35. Jolly CA, Jiang YH, Chapkin RS & McMurray DN (1997) Dietary n-3 polyunsaturated fatty acid modulation of murine lymphoproliferation and interleukin-2 secretion: Correlation with alterations in diacylglycerol and ceramide mass. Journal of Nutrition 127, 37-43.
36. Jolly CA, Laurenz JC, McMurray DN & Chapkin RS (1996) Diacylglycerol and ceramide kinetics in primary cultures of activated T-lymphocytes. Immunology Letters 49, 43-48.
37. Jolly CA, McMurray DN & Chapkin RS (1998) Effect of dietary n-3 fatty acids on interleukin-2 and interleukin-2 receptor α expression in activated murine lymphocytes. Prostaglandins, Leukotrienes and Essential Fatty Acids 58, 289-293.
38. Jump DB, Clarke SD, Thelen A, Liimatta M, Ren B & Badin MV (1997) Dietary fat, genes, and human health. In Dietary Fat and Cancer, pp. 167-176 [American Institute for Cancer Research, editors]. New York: Plenum Press.
39. Kelley DS, Taylor PC, Nelson GJ & Mackey BE (1998) Arachidonic acid supplementation enhances synthesis of eicosanoids without suppressing immune functions in young healthy men. Lipids 33, 125-130.
40. Kremer JM, Bigaouette J, Michalek AV, Lininger L, Huyck C, Timchalk MA, Rynes RI, Zeiminski J & Bartholomew LE (1985) Effects of manipulating dietary fatty acids on clinical manifestations of rheumatoid arthritis. Lancet i, 184-187.
41. Kremer JM, Jubiz W, Michalek A, Rynes RI, Bartholomew LE, Bigaouette J, Timchalk M, Beeler D & Lininger L (1987) Fish oil fatty acid supplementation in active rheumatoid arthritis. A double-blinded, controlled, crossover study. Annals of Internal Medicine 106, 497-502.
42. Kulkarni AB, Hug CG, Becker D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM & Karlsson S (1993) Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proceedings of the National Academy of Sciences USA 90, 770-774.
43. Lin C (1994) Treatment of IgA nephropathy. Springer Seminars in Immunopathology 16, 121-127.
44. Luan X, Zhao W, Chandrasekar B & Fernandes G (1995) Calorie restriction modulates lymphocyte subset phenotype and increases apoptosis in MRL/1pr mice. Immunology Letters 47, 181-186.
45. McDonnell TJ & Korssmeyer SJ (1991) Progression from lymphoid hyperplasia to high grade malignant lymphoma in mice trans-genic for the t(14 : 18). Nature 349, 254-256.
46. Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA & Gorbach SL (1991) Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: Comparison between young and older women. Journal of Nutrition 121, 547-555.
47. Morphake P, Briety J, Darlametsos I, Tsipas G & Gkikas G (1994) Alteration of cyclosporine CsA-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. Prostaglandins, Leukotrienes and Essential Fatty Acids 50, 29-35.
48. Nordkild PK, Graff J, Jorgensen HE & Fugleberg S (1993) Fish oil and antioxidant supplements reduce erythropoietin requirement in haemodialysis patients. Nephrology Dialysis and Transplantation 8, 569.
49. Oberhammer F, Fritsch G, Pavelka M, Froschl G, Tiefenbacher R, Purchio T & Schulte-Hermann R (1992) Induction of apoptosis in cultured hepatocytes and in the regressing liver by transforming growth factor-beta 1 occurs without activation of an endonuclease. Toxicology Letters 64, 701-704.
50. Ogawa N, Dang H & Talal N (1995) Apoptosis and autoimmunity. Journal of Autoimmunity 8, 1-19.
51. 2 production but have different effects on lymphocyte functions and cell-mediated immunity. Lipids 33, 171-180.
52. Petterson EE, Rekola S, Berglund L, Sundqvist KG, Angelin B, Diczfalusy U, Bjorkhem I & Bergstrom J (1994) Treatment of IgA nephropathy with omega-3 polyunsaturated fatty acids: A prospective, double-blind, randomized study. Clinical Nephrology 41, 183-190.
53. Ren B, Thelen AP, Peters JM, Ganzalex FJ & Jump DB (1997) Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor α. Journal of Biological Chemistry 272, 26827-26832.
54. Renier G, Skamene E, DeSanctis J & Radzioch D (1993) Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Arteriosclerosis and Thrombosis 13, 1515-1524.
55. Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, Annunziata N & Doetschman T (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359, 693-699.
56. Troyer DA, Chandrasekar B, Barnes J & Fernandes G (1997) Calorie restriction decreases platelet derived growth factor-A and thrombin receptor mRNA expression in autoimmune murine lupus nephritis. Clinical and Experimental Immunology 108, 58-62.
57. Troyer DA & Fernandes G (1996) Nutrition and apoptosis. Nutrition Research 16, 1959-1987.
58. Vassilopoulos D, Zurier RB, Rossetti RG & Tsokos GC (1997) Gammalinolenic acid and dihomogammalinolenic acid suppress the CD3-mediated signal transduction pathway in human T cells. Clinical Immunology and Immunopathology 83, 237-244.
59. Venkatraman JT, Chandrasekar B, Kim JD & Fernandes G (1994) Effects of n-3 and n-6 fatty acids on the activities and expression of hepatic antioxidant enzymes in autoimmune-prone NZB x NZW F1 mice. Lipids 29, 561-568.
60. Yaqoob P, Newsholme EA & Calder PC (1995) The effect of fatty acids on leucocyte subsets and proliferation in rat whole blood. Nutrition Research 15, 279-287.