Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene

Genomics

Volumn 53, Issue 1, 1998, Pages 69-80

  Winand, Nena J ^a   Panzer, Jessica A ^a   Kolodner, Richard D ^b  

^a Cornell University ^*  (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; GENE EXPRESSION; GENE STRUCTURE; IMMUNE SYSTEM; MEIOSIS; MOLECULAR CLONING; MOLECULAR GENETICS; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; TESTIS; THYMUS;

CAENORHABDITIS ELEGANS; EUKARYOTA; INVERTEBRATA; SACCHAROMYCES CEREVISIAE;

EID: 0032191204     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5447     Document Type: Article

References (64)

1. Acharya S., Wilson T., Gradia S., Kane M. F., Guerrette S., Marsischky G. T., Kolodner R., Fishel R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc. Natl. Acad. Sci. USA. 93:1996;13629-13634.
2. Alani E. TheSaccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;5604-5615.
3. Alani E., Lee S., Kane M. F., Griffith J., Kolodner R. D. Saccharomyces cerevisiae. J. Mol. Biol. 265:1997;289-301.
4. Alani E., Reenan R. A. G., Kolodner R. D. Interaction between mismatch repair and genetic recombination inSaccharomyces cerevisiae. Genetics. 137:1994;19-39.
5. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
6. Baker S. M., Bronner C. E., Zhang I., Plug A., Robatzek M., Warren G., Elliot E. A., Yu J., Ashley T., Arnheim N., Flavell R. A., Liskay R. M. Male mice defective in the DNA mismatch repair genePMS2. Cell. 82:1995;309-320.
7. Baker S. M., Plug A. W., Prolla T. A., Bronner C. E., Harris A. C., Yao X., Christie D. M., Monell C., Arnheim N., Bradley A., Ashley T., Liskay R. M. Involvement of mouseMlh1. Nat. Genet. 13:1996;336-342.
8. Bawa S., Xiao W. A mutation in theMSH5. Cancer Res. 57:1997;2715-2720.
9. Bhattacharyya N. P., Skandalis A., Ganesh A., Groden J., Meuth M. Mutator phenotype in human colorectal carcinoma cell lines. Proc. Natl. Acad. Sci. USA. 91:1994;6319-6323.
10. Boyer J. C., Umar A., Risinger J., Kane M. F., Lipford J., Barrett J. C., Kolodner R. D., Kunkel T. A. Microsatellite instability, mismatch repair deficiency and genetic defects in human cancer cell lines. Cancer Res. 55:1995;6062-6070.
11. Bronner C. E., Baker S. M., Morrison P. T., Warren G., Smith L. G., Lescoe M. K., Kane M., Earabino C., Lipford J., Lindblom A., Tannergard P., Bollag R. J., Godwin A. R., Ward D. C., Nordenskjold M., Fishel R., Kolodner R., Liskay R. M. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature. 368:1994;258-261.
12. Chambers S. R., Hunter N., Louis E. J., Borts R. H. The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss. Mol. Cell. Biol. 16:1996;6110-6120.
13. Chi N.-W., Kolodner R. D. Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J. Biol. Chem. 269:1994;29984-29992.
14. Datta A., Adjiri A., New L., Crouse G. F., Jinks-Robertson S. Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins inSaccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;1085-1093.
15. de Wind N., Dekker M., Berns A., Radman M., te Reile H. Inactivation of the mouseMsh2. Cell. 82:1995;321-330.
16. Drummond J. T., Li G.-M., Longley M. J., Modrich P. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science. 268:1995;1909-1912.
17. Edelmann W., Cohen P. E., Kane M., Lau K., Morrow B., Bennett S., Umar A., Kunkel T., Cattoretti G., Chaganti R., Pollard J. W., Kolodner R. D., Kucherlapati R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 85:1996;1125-1134.
18. Edelmann W., Yang K., Umar A., Heyer J., Lau K., Fan K., Liedtke W., Cohen P. E., Kane M. F., Lipford J. R., Yu N., Crouse G. F., Pollard J. W., Kunkel T., Lipkin M., Kolodner R., Kucherlapati R. Mutation in the mismatch repair geneMsh6. Cell. 91:1997;467-477.
19. Fishel R., Lescoe M. K., Rao M. R., Copland N. G., Jenkins N. A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyosis colon cancer. Cell. 75:1993;1027-1038.
20. Fitzgerald M., Shenk T. The sequence of 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs. Cell. 24:1981;251-260.
21. Gradia S., Acharya S., Fishel R. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell. 91:1997;995-1005.
22. Gyapay G., Morissette J., Vignal A., Dib C., Fizames C., Millasseau P., Marc S., Bernardi G., Lathrop M., Weissenbach J. The 1993-94 Généthon human genetic linkage map. Nat. Genet. 7:1994;246-339.
23. Habraken Y., Sung P., Prakash L., Prakash S. Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. Curr. Biol. 6:1996;1185-1187.
24. Higgins D. G., Bleasby A. J., Fuchs R. CLUSTAL V: Improved software for multiple sequence alignment. Comput. Appl. Biosci. 8:1992;189-191.
25. Hollingsworth N. M., Ponte L., Halsey C. MSH5,Saccharomyces cerevisiae. Genes Dev. 9:1995;1728-1739.
26. Hudson T. J., Stein L. D., Gerety S. S., Ma J., Castle A. B., Silva J., Slonim D. K., Baptista R., Kruglyak L., Xu S. H., Hu X., Colbert A. M. E., Rosenberg C., Reeve-Daly M. P., Rozen S., Hui L., Wu X., Vestergaard C., Wilson K. M., Bae J. S., Maitra S., Ganiatsas S., Evans C. A., DeAngelis M. M., Ingalls K. A., Nahf R. W., Horton L. T., Anderson M. O., Collymore A. J., Ye W., Kouyoumjian V., Zemsteva I. S., Tam J., Devine R., Courtney D. F., Renaud M. T., Nguyen H., O'Connor T. J., Fizames C., Faure S., Gyapay G., Dib C., Morissette J., Orlin J. B., Birren B. W., Goodman N., Weissenbach J., Hawkins T. L., Foote S., Page D. C., Lander E. S. An STS-based map of the human genome. Science. 270:1995;1945-1954.
27. Hunter N., Chambers S. R., Louis E. J., Borts R. H. The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid. EMBO J. 15:1996;1726-1733.
28. Iaccarino I., Palombo F., Drummond J., Totty N. F., Hsuan J. J., Modrich P., Jiricny J. MSH6, aSaccharomyces cerevisiae. Curr. Biol. 6:1996;484-486.
29. Johnson R. E., Kovvali G. K., Prakash L., Prakash S. Requirement of the yeastMSH3MSH6MSH2. J. Biol. Chem. 271:1996;7285-7288.
30. Kelly, K. Villeneuve, A. M. 1997, C. elegans., http://probe.nal.usda.gov:8300/cgi-bin/webace.
31. Kolodner R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev. 10:1996;1433-1442.
32. Kolodner R. D., Hall N. R., Lipford J., Kane M. F., Morrison P. T., Finan P. J., Burn J., Chapman P., Earabino C., Merchant E., Bishop D. T. Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations. Cancer Res. 55:1995;242-248.
33. Kolodner R. D., Hall N. R., Lipford J., Kane M. F., Rao M. R., Morrison P., Wirth L., Finan P. J., Burn J., Chapman P., Earabino C., Merchant E., Bishop T. Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. Genomics. 24:1994;516-526.
34. Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell. 44:1996;283-292.
35. Leach F. S., Nicolaides N. C., Papadopoulos N., Liu B., Jen J., Parsons R., Peltomäki P., Sistonene P., Aaltonen L. A., Nyström-Lahti M., Guan X.-Y., Zhang J., Meltzer P. S., Yu J.-W., Kao F.-T., Chen D. J., Cerosaletti K. M., Fournier R. E. K., Todd S., Lewis T., Leach R. J., Naylor S. L., Weissenbach J., Mecklin J.-P., Järvinen H., Petersen G. M., Hamilton S. R., Green J., Jass J., Watson P., Lynch H. T., Trent J. M., de la Chapelle A., Kinsler K. W., Vogelstein B. Mutations of mutS homolog in hereditary nonpolyosis colorectal cancer. Cell. 75:1993;1215-1225.
36. Liu B., Parsons R., Papadopoulos N., Nicolaides N. C., Lynch H. T., Watson P., Jass J. R., Dunlop M., Wylie A., Peltomaki P., de la Chapelle A., Hamilton S. R., Vogelstein B., Kinzler K. W. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat. Med. 2:1996;169-174.
37. Marsischky G. T., Filosi N., Kane M. F., Kolodner R. Redundancy ofSaccharomyces cerevisiae. Genes Dev. 10:1996;407-420.
38. Miyaki M., Konishi M., Tanaka K., Kikuchi-Yanoshita R., Muraoka M., Yasuno M., Igari T., Koike M., Chiba M., Mori T. Germline mutation ofMSH6. Nat. Genet. 17:1997;271-272.
39. New L., Liu K., Crouse G. F. The yeast geneMSH3. Mol. Gen. Genet. 239:1993;97-108.
40. Nicolaides N. C., Papadopoulos N., Liu B., Wei Y. F., Carter K. C., Ruben S. M., Rosen C. A., Hazeltine W. A., Fleischmann R. D., Fraser C. M., Adams M. D., Venter J. C., Dunlop M. G., Hamilton S. R., Petersen G. M., de la Chapelle A., Vogelstein B., Kinzler K. W. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 371:1994;75-80.
41. Palombo F., Iaccarino I., Nakajima E., Ikejima M., Shimada T., Jiricny J. hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 6:1996;1181-1184.
42. Papadopoulos N., Nicolaides N. C., Liu B., Parsons R., Lengauer C., Palomobo F., D'Arrigo A., Markowitz S., Wilson J. K., Kinzler K. W., Jiricny J., Vogelstein B. Mutations of GTBP in genetically unstable cells. Science. 268:1995;1915-1917.
43. Papadopoulos N., Nicolaides N. C., Wei Y. F., Ruben S. M., Carter K. C., Rosen C. A., Haseltine W. A., Fleischmann R. D., Fraser C. M., Adams M. D., Venter J. C., Hamilton S. R., Petersen G. M., Watson P., Lynch H. T., Peltomaki P., Mecklin J.-P., de la Chapelle A., Kinzler K. W., Vogelstein B. Mutation of a mutL homolog in hereditary colon cancer. Science. 263:1994;1625-1629.
44. Paquis-Flucklinger V., Santucci-Darmanin S., Paul R., Saunières A., Turc-Carel C., Desnuelle C. Cloning and expression analysis of a meiosis-specific MutS homolog: The humanMSH4. Genomics. 44:1997;188-194.
45. Peltomaki P., Vasen H. F. Mutations predisposing to hereditary non-polyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. Gastroenterology. 113:1997;1146-1158.
46. Pochart P., Woltering D., Hollingsworth N. M. Conserved properties between functionally distinct MutS homologs in yeast. J. Biol. Chem. 48:1997;30345-30349.
47. Proudfoot N. J., Brownlee G. G. 3′ non-coding region sequences in eukaryotic mRNA. Nature. 263:1976;211-214.
48. Reenan R. A. G., Kolodner R. D. Characterization of insertion mutations in theSaccharomyces cerevisiae MSH1MSH2. Genetics. 132:1992a;975-985.
49. Reenan R. A. G., Kolodner R. D. Isolation and characterization of twoSaccharomyces cerevisiae. Genetics. 132:1992b;963-973.
50. Reitmair A. H., Schmits R., Ewel A., Bapat B., Redstow M., Mitri A., Waterhouse P., Mittrucker H.-W., Wakeham A., Liu B., Thomason A., Griesser H., Gallinger S., Ballhausen W. G., Fishel R., Mak T. W. MSH2. Nat. Genet. 11:1995;64-70.
51. Reitmair A. H., Redston M., Cai J. C., Chuang T. C., Bjerknes M., Cheng H., Hay K., Gallinger S., Bapat B., Mak T. W. Spontaneous intestinal carcinomas and skin neoplasms inMSH2. Cancer Res. 56:1996;3842-3849.
52. Reitmair A. H., Risley R., Bristow R. G., Wilson T., Ganesh A., Jang A., Peacock J., Benchimol S., Hill R. P., Mak T. W., Fishel R., Meuth M. Mutator phenotype in Msh2-deficient murine embryonic fibroblasts. Cancer Res. 57:1997;3765-3771.
53. Risinger J. I., Umar A., Boyd J., Berchuck A., Kunkel T. A., Barrett J. C. Mutation of MSH3 in endometrial cancer and evidence for its role in heteroduplex repair. Nat. Genet. 14:1996;102-105.
54. Ross-Macdonald P., Roeder G. S. Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction. Cell. 79:1994;1069-1080.
55. Rzhetsky A., Nei M. Statistical properties of the ordinary least-squares, generalized least-squares, and minimum-evolution methods of phylogenetic inference. J. Mol. Evol. 35:1992;367-375.
56. Selva E. M., Maderazo A. B., Lahue R. S. Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination inSaccharomyces cerevisiae. Mol. Gen. Genet. 257:1997;71-82.
57. Selva E. M., New L., Crouse G. F., Lahue R. S. Mismatch correction acts as a barrier to homeologous recombination inSaccharomyces cerevisiae. Genetics. 139:1995;1175-1188.
58. Shibata D., Peinado M. A., Ionov S., Malkhosyan S., Perucho M. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat. Genet. 6:1994;273-281.
59. Sia E. A., Kokosha R. J., Dominska M., Greenwell P., Petes T. D. Microsatellite instability in yeast: Dependence on repeat unit size and DNA mismatch repair genes. Mol. Cell. Biol. 17:1997;2851-2858.
60. Sugawara N., Paques F., Colaiacovo M., Haber J. E. Role ofSaccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 94:1997;9214-9219.
61. Umar A., Boyer J. C., Thomas D. C., Nguyen D. C., Risinger J. I., Boyd J., Ionov Y., Perucho M., Kunkel T. A. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J. Biol. Chem. 269:1994;14367-14370.
62. Walter M. A., Spillett D. J., Thomas P., Weissenbach J., Goodfellow P. N. A method for constructing radiation hybrid maps of whole genomes. Nat. Genet. 7:1994;22-28.
63. Weissenbach J., Gyapay G., Dib C., Vignal A., Morissette J., Millasseau P., Vaysseix G., Lathrop M. A second-generation linkage map of the human genome. Nature. 359:1992;794-801.
64. Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P. 2.2 Mb of contiguous nucleotide sequence from chromosome III ofC. elegans. Nature. 368:1994;32-38.