B7-1, but not CD28, is crucial for the maintenance of the CD4+ T cell responses in human leprosy

Journal of Immunology

Volumn 161, Issue 5, 1998, Pages 2407-2413

  Schlienger, Katia ^a,d   Uyemura, Koichi ^a   Jullien, Denis ^a   Sieling, Peter A ^a   Rea, Thomas H ^b   Linsley, Peter S ^c,e   Modlin, Robert L ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

^d NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^e ROSETTA INPHARMATICS   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ANTIGEN EXPRESSION; ARTICLE; CLONAL ANERGY; HUMAN; HUMAN CELL; LEPROMATOUS LEPROSY; LYMPHOCYTE CLONE; LYMPHOCYTE PROLIFERATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUBERCULOID LEPROSY;

ANTIBODIES, BLOCKING; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, CD86; ANTIGENS, DIFFERENTIATION; CD4-POSITIVE T-LYMPHOCYTES; CLONE CELLS; HUMANS; IMMUNE SERA; IMMUNOCONJUGATES; LEPROSY, LEPROMATOUS; LEPROSY, TUBERCULOID; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MYCOBACTERIUM LEPRAE; SIGNAL TRANSDUCTION; SKIN;

EID: 0032169280     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. June, C. H., J. A. Bluestone, L. M. Nadler, and C. B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today 15:321.
2. Lenschow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233.
3. Schwanz, R. H. 1992. Costimulation of T lymphocytes: the role of CD28. CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71: 1065.
4. Linsley, P. S., P. M. Wallace, J. Johnson, M. G. Gibson, J. L. Greene, J. A. Ledbetter, C. Singh, and M. A. Tepper. 1992. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science 257:792.
5. Lenschow, D. J., Y. Zeng, J. R. Thistlethwaite, A. Montag, W. Brady, M. G. Gibson, P. S. Linsley, and J. A. Bluestone. 1992. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA41g. Science 257:789.
6. Turka, L. A., P. S. Linsley, H. Lin, W. Brady, J. M. Leiden, R. Q. Wei, M. L. Gibson, X. G. Zheng, S. Myrdal, D. Gordon, T. Bailey, S. F. Bolling, et al. 1992. T-cell activation by the CD28 ligand B7 is required for cardiac rejection in vivo. Proc. Natl. Acad. Sci. USA 89:11102.
7. Finck, B. K., P. S. Linsley, and D. Wofsy. 1994. Treatment of murine lupus with CTLA4Ig. Science 265:1225.
8. Walunas, T. L., D. J. Lenschow, C. Y. Bakker, P. S. Linsley, G. J. Freeman, J. M. Green, C. B. Thompson, and J. A. Bluestone. 1994. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1:405.
9. Grib ben, J. G., G. J. Freeman, V. A. Boussiotis, P. Rennert, C. L. Jellis, E. Greenfield, M. Barber, V. A. Restivo Jr., X. Ke, G. S. Gray, and L. M. Nadler. 1995. CTLA4 mediates antigen-specific apoptosis of human T cells. Proc. Natl. Acad. Sci. USA 92:811.
10. Krummel, M. F., and J. P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
11. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J. Immunol. 155:1032.
12. Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
13. Waterhouse, P., J. M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K. P. Lee, C. B. Thompson, H. Griesser, and T. W. Mak. 1995. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 270: 985.
14. Leach, D. R., M. F. Krummel, and J. P. Allison. 1996. Enhancement of antitumor immunity by CTLA-4 blockade. Science 271:1734.
15. Perrin, P. J., J. H. Maldonado, T. A. Davis, C. H. June, and M. K. Racke. 1996. CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis. J. Immunol. 157:1333.
16. Krummel, M. F., and J. P. Allison. 1996. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:2533.
17. Walunas, T. L., C. Y. Bakker, and J. A. Bluestone. 1996. CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 183:2541.
18. Karandikar, N. J., C. L. Vanderlugt, T. L. Walunas, S. D. Miller, and J. A. Bluestone. 1996. CTLA-4: a negative regulator of autoimmune disease. J. Exp. Med. 184:783.
19. Yamamura, M., K. Uyemura, R. J. Deans, K. Weinberg, T. H. Rea, B. R. Bloom, and R. L. Modlin. 1991. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. [Published erratum appears in 1992 Science 255:12.] Science 254:277.
20. Salgame, P., J. S. Abrams, C. Clayberger, H. Goldstein, J. Convit, R. L. Modlin, and B. R. Bloom. 1991. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 254:279.
21. Ridley, D. S., and W. H. Jopling. 1966. Classification of leprosy according to immunity: a five-group system. Int. J. Lepr. Other Mycobact. Dis. 34:255.
22. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
23. Yamamura, M., X. H. Wang, J. D. Ohmen, K. Uyemura, T. H. Rea, B. R. Bloom, and R. L. Modlin. 1992. Cytokine patterns of immunologically mediated tissue damage. J. Immunol. 149:1470.
24. Linsley, P. S., J. L. Greene, P. Tan, J. Bradshaw, J. A. Ledbetter, C. Anasetti, and N. K. Damle. 1992. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes. J. Exp. Med. 176:1595.
25. Sieling, P. A., D. Chatterjee, S. A. Porcelli, T. I. Prigozy, R. J. Mazzaccaro, T. Soriano, B. R. Bloom, M. B. Brenner, M. Kronenberg, P. J. Brennan, and R. L. Modlin. 1995. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269:227.
26. Modlin, R. L., F. M. Hofman, C. R. Taylor, and T. H. Rea. 1983. T lymphocyte subsets in the skin lesions of patients with leprosy. J. Am. Acad. Dermatol. 8:182.
27. Modlin, R. L., V. Mehra, L. Wong, Y. Fujimiya, W. C. Chang, D. A. Horwitz, B. R. Bloom, T. H. Rea, and P. K. Pattengale. 1986. Suppressor T lymphocytes from lepromatous leprosy skin lesions. J. Immunol. 137:2831.
28. Modlin, R. L., J. Melancon-Kaplan, S. M. Young, C. Pirmez, H. Kino, J. Convit, T. H. Rea, and B. R. Bloom. 1988. Learning from lesions: patterns of tissue inflammation in leprosy. Proc. Natl. Acad. Sci. USA 85:1213.
29. Li, S. G., T. H. Ottenhoff, P. Van den Elsen, F. Koning, L. Zhang, T. Mak, and R. R. De Vries. 1990. Human suppressor T cell clones lack CD28. Eur. J. Immunol. 20:1281.
30. Linsley, P., W. Brady, M. Urnes, L. Grosmaire, N. Damle, and J. Ledbetter. 1991. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 174:561.
31. Linsley, P. S. 1995. Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation? J. Exp. Med. 182:289.
32. - T cells: B7-independent costimulation of CD1-restricted T cells. J. Exp. Med. 182:2007.
33. Freeman, G. J., V. A. Boussiotis, A. Anumanthan, G. M. Bernstein, X. Y. Ke, P. D. Rennen, G. S. Gray, J. G. Gribben, and L. M. Nadler. 1995. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523.
34. Creery, W. D., F. Diaz-Mitoma, L. Filion, and A. Kumar. 1996. Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype. Eur. J. Immunol. 26:1273.
35. Van Dijk, A. M., H. G. Otten, S. M. Vercauteren, F. L. Kessler, M. de Boer, L. F. Verdonck, and G. C. de Gast. 1996. Human B7-1 is more efficient than B7-2 in providing costimulation for alloantigen-specific T cells. Eur. J. Immunol. 26: 2275.
36. Morton, P. A., X. T. Fu, J. A. Stewart, K. S. Giacoletto, S. L. White, C. E. Leysath, R. J. Evans, J. J. Shieh, and R. W. Karr. 1996. Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2). J. Immunol. 156:1047.
37. Chambers, B. J., M. Salcedo, and H. G. Ljunggren. 1996. Triggering of natural killer cells by the costimulatory molecule CD80 (B7.1). Immunity 5:311.
38. Shahinian, A., K. Pfeffer, K. P. Lee, T. M. Kundig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261:609.
39. Corry, D. B., S. L. Reiner, P. S. Linsley, and R. M. Locksley. 1994. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J. Immunol. 153:4142.
40. Brown, D. R., J. M. Green, N. H. Moskowitz, M. Davis, C. B. Thompson, and S. L. Reiner. 1996. Limited role of CD28-mediated signals in T helper subset differentiation. J. Exp. Med. 184:803.
41. Lenschow, D. J., K. C. Herold, L. Rhee, B. Patel, A. Koons, H. Y. Qin, E. Fuchs, B. Singh, C. B. Thompson, and J. A. Bluestone. 1996. CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity 5:285.
42. Rulifson, I. C., A. I. Sperling, P. E. Fields, F. W. Fitch, and J. A. Bluestone. 1997. CD28 costimulation promotes the production of Th2 cytokines. J. Immunol. 158: 658.
43. Bluestone, J. A. 1997. Is CTLA-4 a master switch for peripheral cell tolerance? J. Immunol. 158:1989.
44. L induction. J. Immunol. 160:12.
45. Alegre, M.-L., P. J. Noel, B. J. Eisfelder, E. Chuang, M. R. Clark, S. L. Reiner, and C. B. Thompson. 1996. Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J. Immunol. 157:4562.
46. + T cells into subpopulations with distinct cytokine profiles. J. Immunol. 155:2928.
47. + T cells secreting Th1 or Th2 cytokines. Immunity 2:271.
48. + T cells. J. Immunol. 158:1551.
49. Salgame, P., R. Modlin, and B. R. Bloom. 1989. On the mechanism of human T cell suppression. Int. Immunol. 1:121.
50. + T cells is receptor dependent and HLA-DQ restricted. Proc. Natl. Acad. Sci. USA 88:2598.