Treat HIV-1 infection like other infections - Treat it

JAMA

Volumn 280, Issue 1, 1998, Pages 91-93

  Walker, Bruce D ^a,b,c,d   Basgoz, Nesli ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CELL GENESYS INC   (United States)

^c Peptimmune and Point Therapeutics   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRAL ACTIVITY; DRUG CHOICE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NOTE; PRIORITY JOURNAL; TREATMENT PLANNING;

EID: 0032124384     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.280.1.91     Document Type: Note

References (21)

1. Ho DD. Time to hit HIV, early and hard. N Engl J Med. 1995;333:450-451.
2. Deeks S, Volberding P. Antiretroviral therapy for HIV infection: promises and problems. JAMA. 1998;279:1343-1344.
3. Ho DD. Perspectives series: host/pathogen interactions: dynamics of HIV-1 replication in vivo. J Clin Invest. 1997;99:2565-2567.
4. Coffin JM. HIV population dynamics in vivo: implications for genetic variation pathogenesis, and therapy. Science. 1995;267:483-489.
5. Wong JK, Hezareh M, Gunthard HF, et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science. 1997;278: 1291-1295.
6. Embretson J, Zupancic M, Ribas JL, et al. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature. 1993;362:359-362.
7. Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature. 1993;362:355-358.
8. Heath SL, Tew JG, Szakal AK, Burton GF. Follicular dendritic cells and human immunodeficiency virus infectivity. Nature. 1995:377:740-744.
9. Pantaleo G, Fauci AS. Immunopathogenesis of HIV infection. Ann Rev Microbiol. 1996;50:825-854.
10. + T-cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nat Med. 1997;3:533-540.
11. Kelleher AD, Carr A, Zaunders J, Cooper DA. Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir. J Infect Dis. 1996;173:321-329.
12. + T cell homeostasis and function in advanced HIV disease. Science. 1997;277:112-116.
13. Angel JB, Kumar A, Parato K, et al. Improvement in cell-mediated immune function during potent anti-human immunodeficiency virus therapy with ritonavir plus saquinavir. J Infect Dis. 1998;177:898-904.
14. Currier JS, Williams PL, Grimes JM, Squires KS, Fischl MA, Hammer SM. Incidence rates and risk factors for opportunistic infections in a phase III trial comparing indinavir + ZDV to ZDV + 3TC. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections; February 1-5, 1998; Chicago, Ill.
15. Harrer T, Harrer E, Kalams SA, et al. Strong cytotoxic T cell and weak neutralizing antibody responses in a subset of persons with stable nonprogressing HIV type 1 infection. AIDS Res Hum Retroviruses. 1996;12:585-592.
16. Harrer T, Harrer E, Kalams SA, et al. Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection: breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load. J Immunol. 1996;156:2616-2623.
17. + T cell responses associated with control of viremia. Science. 1997;278: 1447-1450.
18. Spruance SL, Pavia AT, Mellors JW, et al, for the Bristol-Myers Squibb Stavudine/019 Study Group. Clinical efficacy of monotherapy with stavudine compared with zidovudine in HIV-infected, zidovudine-experienced patients: a randomized, double-blind, controlled trial. Ann Intern Med. 1997; 126:355-363.
19. Miller KD, Jones E, Yanovski JA, Shankar R, Feuerstein I, Falloon J. Visceral abdominal-fat accumulation associated with use of indinavir. Lancet. 1998; 351:871-875.
20. Lo JC, Mulligan K, Tai VW, Algren H, Schambelan M. "Buffalo hump" in men with HIV-1 infection. Lancet. 1998;351:867-870.
21. Miller K, Daly P, Sentochnik D, et al. Pseudo-Cushing's syndrome in human immunodeficiency virus-infected patients. Clin Infect Dis. In press.