EGF-induced redistribution of erbB2 on breast tumor cells: Flow and image cytometric energy transfer measurements

Cytometry

Volumn 32, Issue 2, 1998, Pages 120-131

  Nagy, Péter ^a   Bene, László ^a   Balázs, Margit ^a   Hyun, William C ^b   Lockett, Steven J ^c   Chiang, Nancy Y ^d   Waldman, Frederick ^b   Feuerstein, Burt G ^b   Damjanovich, Sándor ^a   Szöllosi, János ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d GENENTECH INC   (United States)

Author keywords

Breast cancer; EGF receptor; Energy transfer; erbB2; Homoassociation

Indexed keywords

CELL SURFACE PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN F(AB) FRAGMENT; PROTEIN TYROSINE KINASE; TRANSFERRIN RECEPTOR;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; ENERGY TRANSFER; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMAGE CYTOMETRY; PRIORITY JOURNAL;

EID: 0032101894     PISSN: 01964763     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0320(19980601)32:2<120::AID-CYTO7>3.0.CO;2-P     Document Type: Article

References (52)

1. Alimandi M, Romane A, Curia MC, Muraro R, Fedi P, Aaronson SA, DiFiore PP, Kraus MH: Cooperative signaling of erbB3 and erbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 10:1813-1821, 1995.
2. HER2 monoclonal antibody in patients with HER2/neu overexpressing mctastatic breast cancer. J Clin Oncol 3:737-744, 1996.
3. Baulida J, Kraus MH, Alimandi M, Di Fiore PP, Carpenter G: All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J Biol Chem 271:5251-5257, 1996.
4. Beerli RR, Hynes NE: Epidermal growth factor-related peptides activate distinct subsets of erbB receptors and differ in their biological activities. J Biol Chem 271:6071-6076, 1996.
5. Bene L, Szöllosi J, Balázs M, Mátyus L, Gáspár R Ameloot M, Dale RE, Damjanovich S: Major histocompatibility complex class I protein conformation altered by transmembrane potential changes. Cytometry 27:353-357, 1997.
6. Carraway KL, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, Diamonti AJ, Vandlen RL, Cantley LC, Cerione RA: The erbB3 gene product is a receptor for heregulin. J Biol Chem 260:14303-14306, 1994.
7. Chang H, Riese DJ, Gubert W, Stern D, McMahan UJ: Ligands for erbB-family receptors encoded by a ncuregulin-Iike gene. Nature 287:509-512, 1997.
8. Chen Q, Lentz, BR: Fluorescence resonance energy transfer study of shape changes in membrane-bound bovine prothrombin and meizothrombin. Biochemistry 36:4701-4711, 1997.
9. Cohen BD, Green JM, Foy L, Fell HP: The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cells. J Biol Chem 271:4813-4818, 1996.
10. Damjanovich S, Gáspár R: Dynamic receptor superstructures at the plasma membrane. Q Rev Biophys 30:67-106, 1997.
11. Di Fiore PP, Segatto O, Lonardo F, Fazioli F, Pierce JH, Aaronson SA: The carboxy-terminal domains of erbB2 and epidermal growth factor receptor exert different regulatory effects on intrinsic receptor tyrosine kinase function and transforming activity. Mol Cell Biol 10:2749-2756, 1990.
12. Eisenger J: Energy transfer and dynamic structure. Q Rev Biophys 9:21-33, 1976.
13. Fendly BM, Winget M, Hudziak RM, Lipari MT, Napier MA, Ullrich A: Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res 50:1550-1558, 1990.
14. Gadelia TWJ Jr, Jovin DJA, Jovin TM: Visualization of fipid-receptor interactions on single cells by time-resolved imaging fluorescence microscopy. J Fluorescence 4:295-298, 1994.
15. Guo C, Dower SK, Holowka D, Baird B: Fluorescence resonance energy transfer reveals interleukin (IL)-1 dependent aggregation of 1L-1 type I receptors that correlated with receptor activation. J Biol Chem 270:27562-27568, 1995.
16. Haerslev T, Jacobsen GK: c-erbB2 oncoprotein is not an independent prognostic parameter in primary breast carcinoma. An immunohistochemical study. APMIS 102:612-622, 1994.
17. Heldin CH: Dimerization of cell surface receptors in signal transduction. Cell 80:213-223, 1995.
18. erbB2. Science 256:1205-1209, 1992.
19. HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol Cell Biol 9:1165-1172, 1989.
20. Hynes NE, Stern DF: The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim Biophys Acta 1198:165-184, 1994.
21. Jovin TM, Jovin DJA: FRET microscopy: Digital imaging of fluorescence resonance energy transfer. Application in cell biology. In: Cell Structure and Function by Microspectrofluorometry, Kohen E, Hirschberg JG (eds). Academic Press, San Diego, 1989, pp 99-117.
22. Karunagaran D, Tzahar E, Liu N, Wen D, Yarden Y: Neu differentiation factor inhibits EGF binding. J Biol Chem 270:9982-9990, 1995.
23. Klapper LN, Vaisman N, Hurwitz E, Pinkas-Kramarski R, Yarden Y, Sela M: A subclass of tumor-inhibitory antibodies to ErbB2/HER2 blocks crosstalk with growth factor receptors. Oncogene 14:2099-2109, 1997.
24. Lemmon MA, Schlessinger J: Regulation of signal transduction of signal diversity by receptor oligomerization. Trends Biochem Sci 19:459-463, 1994.
25. Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX: Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 56:1457-1465, 1996.
26. Li PM, Goldstein BJ: Cell density-dependent changes in the insulin action pathway: Evidence for involvement of protein-tyrosine phosphatases. Cell Biochem 61:31-38, 1996.
27. Lipponen HJP, Aaltomaa S, Syrjanen S, Syrjanen K: c-erbB2 oncogene related to p53 expression, cell proliferation and prognosis in breast cancer. Anticancer Res 13:1147-1152, 1993.
28. Lupu R, Colomer R, Kannan B, Lippman ME: Characterization of a growth factor that binds exclusively to the erbB2 receptor and induces cellular responses. Proc Natl Acad Sci USA 89:2287-2291, 1992.
29. Marikovski M, Lavi S, Pinkas-Kramarski R, Karunagaran D, Liu N, Wen D, Yarden Y: ErbB-3 mediated differential mitogenic effects of NDF/heregulin isoforms on mouse keratinocytes. Oncogene 10:1403-1411, 1995.
30. Marte BM, Jeschke M, Graus-Porta D, Taverna D, Hofer P, Groner B, Yarden Y, Hynes NE: Neu differentiation factor/heregulin modulates growth and differentiation of HC11 mammary epithelial cells. Mol Endocrinol 9:14-23, 1995.
31. Mátyus L, Bene L, Heiligen H, Rausch J, Damjanovich S: Distinct association of transferrin receptor with HLA class I molecules on HUT-102B and JY cells. Immunol Lett 44:203-208, 1995.
32. Pagano RE, Martin OC, Kang HC, Haugland RP: A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: Accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor. J Cell Biol 6:1267-1279, 1991.
33. Quenel N, Wafflart J, Bonichon F, de Mascaret I, Trojani M, Durand M, Avril A, Coindre JM: The prognostic value of c-erbB2 in primary breast carcinomas: A study on 942 cases. Breast Cancer Res Treat 35:283-291, 1995.
34. Radinsky R, Risin S, Fan D, Dong Z, Bielenberg D, Bucana CD, Fidler IJ: Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1:19-31, 1995.
35. HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth. Growth Regul 1:72-82, 1991.
36. Schecter AL, Hung MC, Vaidyanathan L, Weinberg RA, Yang-Feng TA, Francke LI, Ullrich A, Coussens L: The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. Science 229:976-978, 1985.
37. van Slooten HJ, Bonsing BA, Hiller AJ, Colbern GT, van Dierendonck JH, Corne CJ, Smith HS: Outgrowth of BT-474 human breast cancer cells in immune-deficient mice: A new in vitro model for hormonedependent breast cancer. Br J Cancer 72:22-30, 1995.
38. Sulzer B, De Boer RJ, Pcrelson AS: Cross-linking reconsidered: Binding and cross-linking fields and the cellular response. Biophys J 70:1154-1168, 1996.
39. Szabó G Jr, Pine PS, Weaver JL, Kasari M, Aszalos A: Epitope mapping by photobleachmg fluorescence resonance energy transfer measurements using a laser scanning microscope. Biophys J 61:661-670, 1992.
40. Szollosi J, Tron L, Damjanovich S, Heliwell S, Jovin DJA, Jovin TM: Fluorescence energy transfer measurements on cell surfaces: A critical comparison of steady-state fluorimetric and flow cytometric methods. Cytometry 5:210-216, 1984.
41. Szöllosi J, Damjanovich S, Balázs M, Nagy P, Trón L, Fulwyler MJ, Broclsky FM: Physical association between MHC class I and class II molecules detected on the cell surface by flow cytometric energy transfer. J Immunol 143:208-213, 1989.
42. Szöllosi J, Feuerstein BG, Hyun WC, Das MK, Marion LJ: Attachment of A172 human glioblastoma cells affects calcium signa/ing: A comparison of image cytometry, flow cytometry, and spectrofluorimetry. Cytometry 12:707-716, 1991.
43. HER-2- overexpression, and intratumor heterogeneity in human breast cancer. Cancer Res 55:5400-5407, 1995.
44. Szöllosi J, Horejsi V, Bene L, Angelisova P, Damjanovich S: Supramo-lecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY. J Inununol 57:2939-2946, 1996.
45. Tetu T, Brisson J: Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapy. Cancer 73:2359-2365, 1994.
46. Traverse S, Seedorf K, Paterson H, Marshall CJ, Cohen P, Ullrich A: EOF triggers neuronal differentiation of PC 12 cells that overexpress the EGF receptor. Curr Biol 4:696-701, 1994.
47. Trón L, Szöllosi J, Damjanovich S, Helliwell SH, Jovin DJA, Jovin TM: Flow cytometric measurement of fluorescence resonance energy transfer on cell surfaces. Quantitative evaluation of the transfer efficiency on a cell-by-cell basis. Biophys J 45:939-946, 1984.
48. Wada T, Qian XL, Greene MI: Intramolecular association of the p185neu protein and EGF receptor modulates EGF receptor function. Cell 61:1339-1347, 1990.
49. Wagner CL, Mascelli MA, Neblock DS, Weisman HF, Coller BS, Jordan RE; Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets. Blood 88:907-914, 1996.
50. Wallasch C, Weiss FU, Neiderfellner G, Jallal B, Issing W, Ullrich A: Heregulin-dependent regulation of HER2/neu oncogenic signaling by hclerodijnerization with HER3. EMBO J 14:4267-4275, 1995.
51. Wiltschke C, Tyl E, Speiser P, Steininger A, Zeillinger R, Kury F, Czerwenka K, Kubista E, Preis P, Krainer M, Zielinksi CC: Increased natural killer cell activity correlate with low or negative expression of the HER2/neu oncogene in patients with breast cancer. Cancer 73:135-139, 1994.
52. Young RM, Arnette JK, Roess DA, Barisas BG: Quantitaten of fluorescence energy transfer between cell surface proteins via fluorescence donor photobleaching kinetics. Biophys J 67:881-888, 1994.