Defining the interactions between intermediate filaments and desmosomes

Journal of Cell Biology

Volumn 141, Issue 5, 1998, Pages 1229-1241

  Smith, Elizabeth A ^a   Fuchs, Elaine ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESMOCOLLIN; DESMOPLAKIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; KERATIN; LINK PROTEIN; MEMBRANE PROTEIN; PLAKOGLOBIN; PLAKOPHILIN 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESMOSOME; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; KERATINOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DESMOCOLLINS; DESMOGLEIN 1; DESMOGLEINS; DESMOPLAKINS; DESMOSOMES; EPIDERMIS; GAMMA CATENIN; HUMANS; INTERMEDIATE FILAMENTS; KERATINOCYTES; KERATINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLAKOPHILINS; PROTEINS;

ANIMALIA;

EID: 0032100705     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.141.5.1229     Document Type: Article

References (56)

1. Barth, A.I., I.S. Nathke, and W.J. Nelson. 1997. Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9:683-690.
2. Bierkamp, C., K.J. McLaughlin, H. Schwarz, O. Huber, and R. Kemler. 1996. Embryonic heart and skin defects in mice lacking plakoglobin. Dev. Biol. 180:780-785.
3. Bornslaeger, E.A., C.M. Corcoran, T.S. Stappenbeck, and K.J. Green. 1996. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134: 985-1001.
4. Buxton, R.S., P. Cowin, W.W. Franke, D.R. Garrod, K.J. Green, I.A. King, P.J. Koch, A.I. Magee, D.A. Rees, J.R. Stanley, and M.S. Steinberg. 1993. Nomenclature of the desmosomal cadherins. J. Cell Biol. 121:481-483.
5. Candi, E., E. Tarcsa, J.J. Digiovanna, J.G. Compton, P.M. Elias, L.N. Marekov, and P.M. Steinert. 1998. A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases. Proc. Natl. Acad. Sci. USA. 95:2067-2072.
6. Chitaev, N.A., R.E. Leube, R.B. Troyanovsky, L.G. Eshkind, W.W. Franke, and S.M. Troyanovsky. 1996. The binding of plakoglobin to desmosomal cadherins: patterns of binding sites and topogenic potential. J. Cell Biol. 133: 359-369.
7. 2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion. J. Cell Biol. 138:193-201.
8. Cowin, P., H.-P. Kapprell, W.W. Franke, J. Tamkun, and R.O. Hynes. 1986. Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell. 1063-1073.
9. Fitzpatrick, T.B., A.Z. Eisen, K. Wolff, I.M. Freedberg, and K.F. Austen. 1993. Dermatology in general medicine. 4th ed. Vol. I and II. McGraw-Hill, Inc., New York.
10. Green, K.J., R.D. Goldman, and R.L. Chisholm. 1988. Isolation of cDNAs encoding desmosomal plaque proteins: evidence that bovine desmoplakins I and II are derived from two mRNAs and a single gene. Proc. Natl. Acad. Sci.USA. 85:2613-2617.
11. Green, K.J., D.A.D. Parry, P.M. Steinert, M.L.A. Virata, R.M. Wagner, B.D. Angst, and L.A. Nilles. 1990. Structure of the human desmoplakins: implications for function in the desmosomal plaque. J. Biol. Chem. 265:2603-2612.
12. Green, K.J., M.L. Virata, G.W. Elgart, J.R. Stanley, and D.A. Parry. 1992. Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin: members of a new gene family involved in organization of intermediate filaments. Int. J. Biol. Macromol. 14:145-153.
13. Green, K.J., and J.C. Jones. 1996. Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J. 10:871-881.
14. Gumbiner, B.M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
15. Hatzfeld, M., G.I. Kristjansson, U. Plessman, and K. Weber. 1994. Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family. J. Cell Sci. 107:2259-2270.
16. Heid, H.W., A. Schmidt, R. Zimbelmann, S. Schafer, S. Winter-Simanowski, S. Stumpp, M. Keith, U. Figge, M. Schnolzer, and W.W. Franke. 1994. Cell type-specific desmosomal plaque proteins of the plakoglobin family:plakophilin 1 (band 6 protein). Differentiation. 58:113-131.
17. Irvine, A.D., K.E. McKenna, H. Jenkinson, and A.E. Hughes. 1997. A mutation in the V1 domain of keratin 5 causes epidermolysis bullosa simplex with mottled pigmentation. J. Investig. Dermatol. 108:809-810.
18. Jones, J.C., and K.A. Grelling. 1989. Distribution of desmoplakin in normal cultured human keratinocytes and in basal cell carcinoma cells. Cell Motil. Cytoskeleton. 13:181-194.
19. Kapprell, H.P., K. Owaribe, and W.W. Franke. 1988. Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia. J. Cell Biol. 106:1679-1691.
20. Kelly, D.E. 1966. Fine structure of desmosomes, hemidesmosomes, and an epidermal globular layer in developing newt epidermis. J. Cell Biol. 28:51-72.
21. Kimonis, V., J.J. DiGiovanna, J.M. Yang, S.Z. Doyle, S.J. Bale, and J.G. Compton. 1994. A mutation in the V1 end domain of keratin 1 in non-epidermolytic palmar-plantar keratoderma. J. Investig. Dermatol. 103:764-769.
22. King, I.A., B.D. Angst, D.M. Hunt, M. Kruger, J. Arnemann, and R.S. Buxton. 1997. Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 62:83-96.
23. Koch, P.J., M.J. Walsh, M. Schmelz, M.D. Goldschmidt, R. Zimbelmann, and W.W. Franke. 1990. Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules. Eur. J. Cell Biol. 53:1-12.
24. Koch, P.J., M.D. Goldschmidt, R. Zimblemann, R. Troyanovsky, and W.W. Franke. 1992. Complexity of expression patterns of the desmosomal cadherins. Proc. Natl. Acad. Sci. USA. 89: 353-357.
25. Koch, P.J., and W.W. Franke. 1994. Desmosomal cadherins: another growing multigene family of adhesion molecules. Curr. Opin. Cell Biol. 6:682-687.
26. Kouklis, P., E. Hutton, and E. Fuchs. 1994. Making the connection: keratin intermediate filaments and desmosomes proteins. J. Cell Biol. 127:1049-1060.
27. Kowalczyk, A.P., E.A. Bornslaeger, J.E. Borgwardt, H.L. Palka, A.S. Dhaliwal, C.M. Corcoran, M.F. Denning, and K.J. Green. 1997. The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes. J. Cell Biol. 139:773-784.
28. Kozak, M. 1997. Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucelotides in position +5 and +6. EMBO (Eur. Mol. Biol. Organ.) J. 16:2482-2492.
29. Lersch, R., V. Stellmach, C. Stocks, G. Giudice, and E. Fuchs. 1989. Isolation, sequence and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pair-wise control. Mol. Cell Biol. 9:3155-3168.
30. Marrs, J.A., and W.J. Nelson. 1996. Cadherin cell adhesion molecules in differentiation and embryogenesis. Int. Rev. Cytol. 165:159-205.
31. Mathur, M., L. Goodwin, and P. Cowin. 1994. Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin. J. Biol. Chem. 269:14075-14080.
32. McGrath, J.A., J.R. McMillan, C.S. Shemanko, S.K. Runswick, I.M. Leigh, E.B. Lane, D.R. Garrod, and R.A.J. Eady. 1997. Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome. Nat. Genet. 17: 240-244.
33. Meng, J.J., E.A. Bornslaeger, K.J. Green, P.M. Steinert, and W. Ip. 1997. Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments. J. Biol. Chem. 272:21495-21503.
34. Merdes, A., M. Brunkener, H. Horstmann, and S.D. Geortgatos. 1991. Filensin: a new vimentin-binding, polymerization-competent, and membrane-associated protein of the lens fiber cell. J. Cell Biol. 115:397-410.
35. Mertens, C., C. Kuhn, and W.W. Franke. 1996. Plakophilin 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque. J. Cell Biol. 135:1009-1025.
36. Miller, K., D. Mattey, H. Measures, C. Hopkins, and D. Garrod. 1987. Localisation of the protein and glycoprotein components of bovine nasal epithelial desmosomes by immunoelectron microscopy. EMBO (Eur. Mol. Biol. Organ.) J. 6:885-889.
37. Moll, I., H. Kurzen, L. Langbein, and W.W. Franke. 1997. The distribution of the desmosomal protein, plakophilin 1, in human skin and skin tumors. J. Investig. Dermatol. 108:139-146.
38. Mueller, H., and W.W. Franke. 1983. Biochemical and immunological characterization of desmoplakins I and II, the major polypeptides of the desmosomal plaque. J. Mol. Biol. 163:647-671.
39. O'Keefe, E.J., H.P. Erickson, and V. Bennett. 1989. Desmoplakin I and desmoplakin II: purification and characterization. J. Biol. Chem. 264:8310-8318.
40. Pasdar, M., K.A. Krzeminski, and W.J. Nelson. 1991. Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane. J. Cell Biol. 113:645-655.
41. Pasdar, M., and W.J. Nelson. 1988. Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. II. Morphological analysis. J. Cell Biol. 106:687-695.
42. Roh, J.Y., and J.R. Stanley. 1995. Plakoglobin binding by human Dsg3 (pemphigus vulgaris antigen) in keratinocytes requires the cadherin-like intracytoplasmic segment. J. Investig. Dermatol. 104:720-724.
43. Ruiz, P., V. Brinkmann, B. Ledermann, M. Behrend, C. Grund, C. Thalhammer, F. Vogel, C. Birchmeier, U. Gunthert, W.W. Franke, and W. Birchmeier. 1996. Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. J. Cell Biol. 135:215-225.
44. Schmidt, A., H.W. Heid, S. Schafer, U.A. Nuber, R. Zimbelmann, and W.W. Franke. 1994. Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage. Eur. J. Cell Biol. 65:229-245.
45. Stappenbeck, T.S., E.A. Bornslaeger, C.M. Corcoran, H.H. Luu, M.L. Virata, and K.J. Green. 1993. Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks. J. Cell Biol. 123:691-705.
46. Stappenbeck, T.S., and K.J. Green. 1992. The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells. J. Cell Biol. 116:1197-1209.
47. Studier, F.W., and B.A. Moffatt. 1986. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:113-130.
48. Troyanovsky, S.M., L.G. Eshkind, R.B. Troyanovsky, R.E. Leube, and W.W. Franke. 1993. Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage. Cell. 72:561-574.
49. Troyanovsky, S.M., R.B. Troyanovsky, L.G. Eshkind, R.E. Leube, and W.W. Franke. 1994. Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation. Proc. Natl. Acad. Sci. USA. 91:10790-10794.
50. Troyanovsky, S.M., R.B. Troyanovsky, L.G. Eshkind, V.A. Krutovskikh, R.E. Leube, and W.W. Franke. 1994. Identification of the plakoglobin-binding domain in desmoglein and its role in plaque assembly and intermediate filament anchorage. J. Cell Biol. 127:151-160.
51. Troyanovsky, R.B., N.A. Chitaev, and S.M. Troyanovsky. 1996. Cadherin binding sites of plakoglobin:localization, specificity and role in targeting to adhering junctions. J. Cell Sci. 109:3069-3078.
52. Uttam, J., E. Hutton, P. Coulombe, I. Anton-Lamprecht, O.-C. Yu, T. Gedde-Dahl, J.-D. Fine, and E. Fuchs. 1996. The genetic basis of epidermolysis bullosa simplex with mottled pigmentation. Proc. Natl. Acad. Sci. USA. 93: 9079-9084.
53. Virata, M.L., R.M. Wagner, D.A. Parry, and K.J. Green. 1992. Molecular structure of the human desmoplakin I and II amino terminus. Proc. Natl Acad. Sci. USA. 89:544-548.
54. Wahl, J.K., P.A. Sacco, T.M. McGranahan-Sadler, L.M. Sauppe, M.J. Wheelock, and K.R. Johnson. 1996. Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins:identification of unique and shared domains. J. Cell Sci. 109:1143-1154.
55. Wilson, A.K., P.A. Coulombe, and E. Fuchs. 1992. The roles of the head, tail and R/KLLEGE domains in keratin filament assembly in vitro. J. Cell Biol. 119:401-414.
56. Witcher, L.L., R. Collins, S. Puttagunta, S.E. Mechanic, M. Munson, B. Gumbiner, and P. Cowin. 1996. Desmosomal cadherin binding domains of plakoglobin. J. Biol. Chem. 271:10904-10909.