Cadherin cell adhesion molecules in differentiation and embryogenesis

International Review of Cytology

Volumn 165, Issue , 1996, Pages 159-205

  Marrs, J A ^a   Nelson, W J ^a  

^a INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adherens junction; Cadherin; Catenin; Desmosome; Differentiation; Embryogenesis; Epithelial cell polarity; Membrane cytoskeleton

Indexed keywords

CADHERIN; CATENIN; CELL ADHESION MOLECULE;

CELL DIFFERENTIATION; CELL STRUCTURE; CYTOSKELETON; EMBRYO DEVELOPMENT; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION;

EID: 0029935329     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0074-7696(08)62222-6     Document Type: Review

References (248)

1. H. Aberle S. Butz J. Stappert H. Weissig R. Kemler H. Hoschuetzky Assembly of the cadherin-catenin complex in vitro with recombinant proteins. J. Cell Sci. 107 1994 3655 3663
2. H. Aoyama A. Delouvee J.P. Thiery Cell adhesion mechanisms in gangliogenesis studied in avian embryo and in a model system. Cell Differ. 17 1985 247 260
3. J. Behrens M.M. Mareel R.F. Van W. Birchmeier Dissecting tumor cell invasion: Epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J. Cell Biol. 108 1989 2435 2447
4. J. Behrens L. Vakaet R. Friis E. Winterhager F. Van Roy M.M. Mareel W. Birchmeier Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with temperature-sensitive v- src gene. J. Cell Biol. 120 1993 757 766
5. W. Birchmeier K.M. Weidner J. Behrens Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells. J. Cell Sci. Suppl. 17 1993 159 164
6. 2+ influx and neurite growth in response to purified N-cadherin and laminin. J. Cell Biol. 127 1994 1461 1475
7. J.L. Bixby R. Zhang Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth. J. Cell Biol. 110 1990 1253 1260
8. T.L. Bloom The effects of phorbol ester on mouse blastomeres: A role for protein kinase C in compaction? Development 106 1989 159 171
9. D. Bok Autoradiographic studies on the polarity of plasma membrane receptors in RPE cells. J. Hollyfield The Structure of the Eye 1982 Elsevier North Holland New York 247 256
10. K. Boller D. Vestweber R. Kemler Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J. Cell Biol. 100 1985 327 332
11. R.S. Bradley P. Cowin A.M. Brown Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J. Cell Biol. 123 1993 1857 1865
12. +2-dependent cell-cell adhesion. Cell Adhes. Commun. 1 1993 239 250
13. W.M. Brieher B.M. Gumbiner Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps. J. Cell Biol. 126 1994 519 527
14. P.J. Bryant B. Huettner L.I. Held J. Ryerse J. Szidonya Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila. Dev. Biol. 129 1988 541 554
15. P.J. Bryant O. Schmidt The genetic control of cell proliferation in Drosophila imaginal discs. J. Cell Sci. 17 Suppl. 1990 171 181
16. C.A. Buck Immunoglobulin superfamily: Structure, function and relationship to other receptor molecules. Semin. Cell Biol. 3 1992 179 188
17. S. Butz J. Stappert H. Weissig R. Kemler Plakoglobin and beta-catenin: Distinct but closely related. Science 257 1992 1142 1143
18. R.S. Buxton P. Cowin W.W. Franke D.R. Garrod K.J. Green I.A. King P.J. Koch A.I. Magee D.R. Rees J.R. Stanley M.S. Steinberg Nomenclature of the desmosomal cadherins. J. Cell Biol. 121 1993 481 483
19. R.S. Buxton A.I. Magee Structure and interactions of desmosomal and other cadherins. Semin. Cell Biol. 3 1992 157 167
20. J.M. Claverie J.P. Hardelin R. Legouis J. Levilliers L. Bougueleret M.-G. Marrei C. Petit Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (α-catenin). Genomics 15 1993 13 20
21. J.E. Collins J.E. Lorimer D.R. Garrod S.C. Pidsley R.S. Buxton T.P. Fleming Regulation of desmosomal transcription in mouse preimplantation embryos. Development 121 1995 743 753
22. P.A. Coulombe M.E. Hutton R. Vassar E. Fuchs A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases. J. Cell Biol. 115 1991 1661 1674
23. P. Cowin H.-P. Kapprell W.W. Franke The complement of desmosomal plaque proteins in different cell types. J. Cell Biol. 101 1985 1442 1454
24. P. Cowin H.-P. Kapprell W.W. Franke J. Tamkun R.O. Hynes Plakolobin: A protein common to different kinds of intercellular adhering junctions. Cell 46 1986 1063 1073
25. P. Cowin D. Mattey D. Garrod Identification of desmosomal surface components (desmocollins) and inhibition of desmosome formation by specific Fab'. J. Cell Sci. 70 1984 41 60
26. +-ATPase interact with distinct sites on ankyrin in in vitro assays. J. Biol. Chem. 265 1990 17252 17256
27. R.J. Detrick D. Dickey C.R. Kintner The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos. Neuron 4 1990 493 506
28. P. Devarajan D.A. Scaramuzzino J.S. Morrow Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPasea subunit. Proc. Natl. Acad. Sci. USA 91 1994 2965 2969
29. 2+ channels. Cell 67 1991 21 33
30. P. Doherty L.H. Rowett S.E. Moore D.A. Mann F.S. Walsh Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. Neuron 6 1991 247 258
31. J. Drazba V. Lemmon The role of cell adhesion molecules in neurite outgrowth on Muller cells. Dev. Biol. 138 1990 82 93
32. J.-L. Duband T. Volberg I. Sabany J.P. Thiery B. Geiger Spatial and temporal distribution of the adherens-junction-associated adhesion molecule A-CAM during avian embryogenesis. Development 103 1988 325 344
33. S. Dufour J.-P. Saint-Jeannet F. Broders D. Wedlich J.P. Thiery Differential perturbations in the morphogenesis of anterior structures induced by overexpression of truncated XB- and N-cadherins in Xenopus embryos. J. Cell Biol. 127 1994 521 535
34. G.M. Edelman Cell adhesion and the molecular process of morphogenesis. Annu. Rev. Biochem. 54 1985 135 169
35. G.M. Edelman Cell-adhesion molecules in the regulation of animal form and tissue pattern. Annu. Rev. Cell Biol. 2 1986 81 116
36. G.M. Edelman K.L. Crossin Cell adhesion molecules: Implications for a molecular histology. Annu. Rev. Biochem. 60 1991 155 190
37. G.M. Edelman B.A. Murray R. Mege B.A. Cunningham W.J. Gallin Cellular expression of liver and neural cell adhesion molecules after transfection with their cDNAs results in specific cell-cell binding. Proc. Natl. Acad. Sci. USA 84 1987 8502 8506
38. M.G. Farquhar G.E. Palade Junctional complexes in various epithelia. J. Cell Biol. 17 1963 375 412
39. T.P. Fleming D.R. Garrod A.J. Elsmore Desmosome biogenesis in the mouse preimplantation embryo. Development 112 1991 527 539
40. T.P. Fleming Q. Javed J. Collins M. Hay Biogenesis of structural intercellular junctions during cleavage in mouse embryo. J. Cell Sci. Suppl. 17 1993 119 125
41. T.P. Fleming M.H. Johnson From egg to epithelium. Ann. Rev. Cell Biol. 4 1988 459 485
42. W.W. Franke M.D. Goldshmidt R. Zimbelmann H.M. Mueller D.L. Schiller P. Cowin Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein. Proc. Natl. Acad. Sci. U.S.A. 86 1989 4027 4031
43. W.W. Franke H. Kapprell P. Cowin Plakoglobinis a component of the filamentous subplasmalemmal coat of lens cells. Eur. J. Cell Biology 43 1987 301 315
44. W.W. Franke H.P. Kapprell P. Cowin Immunolocalization of plakoglobin in endothelial junctions: Identification as a special type of Zonulae adhaerentes. Biol. Cell. 59 1987 205 218
45. D.R. Friedlander R.M. Mege B.A. Cunningham G.M. Edelman Cell sorting-out is modulated by both the specificity and amount of different cell adhesion molecules (CAMs) expressed on cell surfaces. Proc. Natl. Acad. Sci. U.S.A. 86 1989 7043 7047
46. S.M. Frisch H. Francis Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124 1994 619 626
47. E. Fuchs Intermediate filaments and disease: Mutations that cripple cell strength. J. Cell Biol. 125 1994 511 516
48. T. Fujimori S. Miyatani M. Takeichi Ectopic expression of N-cadherin perturbs histogenesis in Xenopus embryos. Development 110 1990 97 104
49. T. Fujimori M. Takeichi Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. Mol. Biol. Cell. 4 1993 37 47
50. N. Funayama F. Fagotto P. McCrea B.M. Gumbiner Embryonic axis induction by the armadillo repeat domain of β-catenin: Evidence for intracellular signaling. J. Cell Biol. 128 1995 959 968
51. Y. Furukawa S. Nakatsuru A. Nagafuchi S. Tsukita T. Muto Y. Nakamura A. Horii Structure, expression and chromosomal assignment of the human α-catenin gene. Cytogenet. Cell Genet. 65 1994 74 78
52. B. Geiger Cytoskeleton-associated cell contacts. Curr. Opin. Cell Biol. 1 1989 103 109
53. B. Geiger Z. Avnur T. Volberg T. Volk Molecular domains of adherens junctions. G.M. Edelman J.P. Thiery The Cell in Contact 1985 John Wiley & Sons New York 461 469
54. B. Geiger O. Ayalon Cadherins. Annu. Rev. Cell Biol. 8 1992 307 332
55. L. Goodwin J.E. Hill K. Raynor L. Raszi M. Manabe P. Cowin Desmoglein shows extensive homology to the cadherin family of cell adhesion molecules. Biochem. Biophys. Res. Commun. 173 1990 1224 1230
56. C. Goridis J.-F. Brunet NCAM: Structural diversity, function and regulation of expression. Semin. Cell Biol. 3 1992 189 197
57. G.B. Grunwald The conceptual and experimental foundations of vertebrate embryonic cell adhesion research. S.F. Gilbert A Conceptual History of Modern Embryology 1991 Plenum Press New York 129 158
58. B. Gumbiner B. Stevenson A. Grimaldi The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J. Cell Biol. 107 1988 1575 1587
59. D. Gundersen J. Orlowski E. Rodriguez-Boulan Apical polarity of Na,K-ATPase in retinal pigment epithelium is linked to a reversal of the ankyrin-fodrin submembrane cytoskeleton. J. Cell Biol. 112 1991 863 872
60. D. Gundersen S.K. Powell E. Rodriguez-Boulan Apical polarization of N-CAM in retinal pigment epithelium is dependent on contact with the neural retina. J. Cell Biol. 121 1993 335 343
61. v-Src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J. 12 1993 307 314
62. R.W. Hammerton K.A. Krzeminski R.W. Mays T.A. Ryan D.A. Wollner W.J. Nelson Mechanism forregulating cell surface distribution of Na,K-ATPase in polarized epithelial cells. Science 254 1991 847 850
63. M. Hashimoto O. Niwa Y. Nitta M. Takeichi K. Yokoro Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells. Jpn. J. Cancer Res. 80 1989 459 463
64. K. Hatta T.S. Okada M. Takeichi A monoclonal antibody disrupting calcium-dependent cell-cell adhesion of brain tissues: Possible role of its target antigen in animal pattern formation. Proc. Natl. Acad. Sci. U.S.A. 82 1985 2789 2793
65. K. Hatta S. Takagi H. Fujisawa M. Takeichi Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Dev. Biol. 120 1987 215 227
66. K. Hatta M. Takeichi Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 320 1986 447 449
67. M. Hatzfeld G.I. Kristjansson U. Plessmann K. Weber Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family. J. Cell Sci. 107 1994 2259 2270
68. X. He J.-P. Saint-Jeannet J.R. Woodgett H. Varmus I.B. Dawid Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature (London) 374 1995 617 622
69. M.L. Hermiston J.I. Gordon In vivo analysis of cadherin function in mouse intestinal epithelium: Essential rolesin adhesion, maintenance of differentiation, and regulation of programmed cell death. J. Cell Biol. 129 1995 489 506
70. K. Herrenknecht M. Ozawa C. Eckerskorn F. Lottspeich M. Lenter R. Kemler The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. Proc. Natl. Acad. Sci. U.S.A. 88 1991 9156 9160
71. L. Hinck I.S. Nathke J. Papkoff W.J. Nelson Beta-catenin: A common target for regulation of cell adhesion by Wnt-1 and src signalling pathways. Trends Biochem. Sci. 19 1994 538 542
72. L. Hinck I.S. Näthke J. Papkoff W.J. Nelson Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex formation. J. Cell Biol. 125 1994 1327 1340
73. L. Hinck W.J. Nelson J. Papkoff Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin. J. Cell Biol. 124 1994 729 741
74. Y. Hirai A. Nose S. Kobayashi M. Takeichi Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis II. Skin morphogenesis. Development 105 1989 271 277
75. S. Hirano N. Kimoto Y. Shimoyama S. Hirohashi M. Takeichi Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization. Cell 70 1992 293 301
76. S. Hirano A. Nose K. Hatta A. Kawakami M. Takeichi Calcium-dependent cell-cell adhesion molecules (cadherins): Subclass specificities and possible involvement ofactin bundles. J. Cell. Biol. 105 1987 2501 2510
77. K.J. Hodivala F.M. Watt Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation. J. Cell Biol. 124 1994 589 600
78. I. Hoffmann R. Balling Cloning and expression analysis of a novel mesodermally expressed cadherin. Dev. Biol. 169 1995 337 346
79. J. Holtfreter Experimental studies on the development of the pronephros. Rev. Can. Biol. 3 1944 220 250
80. J.E. Hooper Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature (London) 372 1994 461 464
81. H. Hoschuetzky H. Aberle R. Kemler β-Catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J. Cell Biol. 127 1994 1375 1380
82. J. Hülsken W. Birchmeier J. Behrens E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton. J. Cell Biol. 127 1994 2061 2069
83. F. Hyafil C. Babinet F. Jacob Cell-cell interactions in early embryogenesis: A molecular approach to the role of calcium. Cell 21 1981 927 934
84. H. Inuzuka C. Redies M. Takeichi Differential expression of R- and N-cadherin in neural and mesodermal tissues during early chicken development. Development 113 1991 959 967
85. M.H. Johnson B. Maro M. Takeichi The role of cell adhesion in the synchronization and orientation of polarization in 8-cell blastomeres. J. Embryol. Exp. Morphol. 93 1988 239 255
86. P.H. Jones S. Harper F.M. Watt Stem cell patterning and fate in human epidermis. Cell 80 1995 83 93
87. 2+ in mouse epidermal cells is controlled by E-cadherin. J. Cell Biol. 114 1991 545 555
88. T.-S. Jou D.B. Stewart J. Stappart W.J. Nelson J.A. Marrs Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex. Proc. Natl. Acad. Sci. U.S.A. 92 1995 5067 5071
89. R. Kemler Classical cadherins. Semin. Cell Biol. 3 1992 149 155
90. R. Kemler From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9 1993 317 321
91. R. Kemler C. Babinet H. Eisen F. Jacob Surface antigen in early differentiation. Proc. Natl. Acad. Sci. U.S.A. 74 1977 4449 4452
92. C. Kintner Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 69 1992 225 236
93. Y. Kimura H. Matsunami T. Inoue K. Shimamura N. Uchida T. Ueno T. Miyazaki M. Takeichi Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. Dev. Biol. 169 1995 347 358
94. K.A. Knudsen A. Peralta Soler K.R. Johnson M.J. Wheelock Interaction of α-actinin with the cadherin/catenin cell-cell adhesion complex via α-catenin. J. Cell Biol. 130 1995 67 77
95. K.A. Knudsen M.J. Wheelock Plakoglobin, or an 83-kD homologue distinct from β-catenin, interacts with E-cadherin and N-cadherin. J. Cell Biol. 118 1992 671 679
96. P.J. Koch M.J. Walsh M. Schmelz M.D. Goldschmidt R. Zimbelmann W.W. Franke Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules. Eur. J. Cell Biol. 53 1990 1 12
97. R. Koob M. Zimmerman W. Schoner D. Drenckhahn Colocalization and coprecipitation or ankyrin and Na,K-ATPase in kidney epithelial cells. Eur. J. Cell Biol. 45 1988 230 237
98. N.J. Korman R.W. Eyre V. Klaus-Kovtun J.R. Stanley Demonstration of an adhering junction molecule (plakoglobin) in the autoantigens of pemphigus foiaceus and pemphigus vulgaris. N. Engl. J. Med. 321 1989 631 635
99. P.D. Kouklis E. Hutton E. Fuchs Making the connection: Direct binding between keratin intermediate filaments and desmosomal proteins. J. Cell Biol. 127 1994 1049 1060
100. A.P. Kowalczyk H.L. Palka H.H. Luu L.A. Nilles J.E. Anderson M.J. Wheelock K.J. Green Posttranslational regulation of plakoglobin expression: Influence of the desmosomal cadherins on plakoglobin metabolic stability. J. Biol. Chem. 269 1995 31214 31223
101. A.P. Kowalczyk T.S. Stappenbeck D.A.D. Parry H.L. Palka M.L.A. Virata E.A. Bornslaeger L.A. Nilles K.J. Green Structure and function of desmosomal transmembrane core and plaque molecules. Biophys. Chem. 50 1994 97 112
102. M.G. Lampugnani M. Corada L. Caveda F. Breviario O. Ayalon B. Geiger E. Dejana The molecular organization of endothelial cell to cell junctions: Differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin). J. Cell Biol. 129 1995 203 217
103. L. Larue M. Ohsugi J. Hirchenhain R. Kemler E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc. Natl. Acad. Sci. U.S.A. 91 1994 8263 8267
104. E. Levine C.H. Lee C. Kintner B.M. Gumbiner Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative phenotype. Development 120 1994 901 909
105. C.R. Lombardo D.L. Rimm E. Koslov J.S. Morrow Human recombinant α-catenin binds to spectrin. Mol. Biol. Cell 5 1994 47a
106. P.A. Mahoney U. Weber P. Ononfrechuk H. Biessmann P.J. Bryant C.S. Goodman The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67 1991 853 868
107. J.A. Marrs C. Andersson-Fisone M.C. Jeong L. Cohen-Gould C. Zurzolo I.R. Nabi E. Rodriguez-Boulan W.J. Nelson Plasticity in epithelial cell phenotype: Modulation by expression of different cadherin cell adhesion molecules. J. Cell Biol. 129 1995 507 519
108. +-ATPase distributions in polarized epithelia. J. Cell Biol. 123 1993 149 164
109. M. Mathur L. Goodwin P. Cowin Interactions of the cytoplasmic domain of the desmosomal cadherin Dsgl with plakoglobin. J. Biol. Chem. 269 1994 14075 14080
110. M. Matsunaga K. Hatta M. Takeichi Role of N-cadherin cell adhesion molecules in the histogenesis of neural retina. Neuron 1 1988 289 295
111. N. Matsuyoshi M. Hamaguchi S. Taniguchi A. Nagafuchi S. Tsukita M. Takeichi Cadherin-mediated cell-cell adhesion is perturbed by v- src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118 1992 703 714
112. P.D. McCrea W.M. Brieher B.M. Gumbiner Induction of a secondary body axis in Xenopus by antibodies to β-catenin. J. Cell Biol. 123 1993 477 484
113. P.D. McCrea C.W. Turck B. Gumbiner A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science 254 1991 1359 1361
114. A.P. McMahon A. Bradley The Wnt -1 ( int -1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62 1990 1073 1085
115. A.P. McMahon R.T. Moon Ectopic expression of the proto-oncogene int -1 in Xenopus embryos leads to duplication of the embyronic axis. Cell 58 1989 1075 1084
116. H. McNeill M. Ozawa R. Kemler W.J. Nelson Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell 62 1990 309 316
117. H. McNeill T. Ryan S.J. Smith W.J. Nelson Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion. J. Cell Biol. 120 1993 1217 1226
118. S. Miyatani K. Shimamura M. Hatta A. Nagafuchi A. Nose M. Matsunaga K. Hatta M. Takeichi Neural cadherin: Role in selective cell-cell adhesion. Science 245 1989 631 635
119. 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc. Natl. Acad. Sci. U.S.A. 91 1994 8856 8860
120. A.I. Morrison S. Keeble F.M. Watt The peanut lectin-binding glycoproteins of human epidermal keratinocytes. Exp. Cell Res. 177 1988 247 256
121. +-ATPase in Madin-Darby canine kidney cells and in intact renal tubule cells. J. Cell Biol. 108 1989 455 465
122. A. Moscona H. Moscona Dissociation and aggregation of cells from organ rudiments of the early chick embryos. J. Anat. 86 1952 287 301
123. A.A. Moscona Cell suspensions from organ rudiments of chick embryos. Exp. Cell. Res. 3 1952 536 539
124. C. Murphy-Erdosh E.W. Napolitano L.F. Reichardt The expression of B-cadherin during embryonic chick development. Dev. Biol. 161 1994 107 125
125. C. Murphy-Erdosh C.K. Yoshida N. Paradies L.F. Reichardt The cadherin-binding specificities of B-cadherin and LCAM. J. Cell Biol. 129 1995 1379 1390
126. L.S. Musil B.A. Cunningham G.M. Edelman D.A. Goodenough Differential phosphorylation of the gap junction protein Connexin43 in junctional communication-competent and -deficient cell lines. J. Cell Biol. 111 1990 2077 2088
127. I.R. Nabi A.P. Mathews L. Cohen-Gould D. Gundersen E. Rodriguez-Boulan Immortalization of polarized ratretinal pigmented epithelium. J. Cell Sci 104 1993 37 49
128. A. Nagafuchi S. Ishihara S. Tsukita The roles of catenins in the cadherin-mediated cell adhesion: Function alanalysis of E-cadherin-α catenin fusion molecules. J. Cell Biol. 127 1994 235 246
129. A. Nagafuchi Y. Shirayoshi K. Okazaki K. Yasuda M. Takeichi Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature (London) 329 1987 340 343
130. A. Nagafuchi M. Takeichi Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7 1988 3679 3684
131. A. Nagafuchi M. Takeichi Transmembrane control of cadherin-mediated cell adhesion: A 94 kd protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regul. 1 1989 37 44
132. A. Nagafuchi M. Takeichi S. Tsukita The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression. Cell 65 1991 849 857
133. A. Nagafuchi S. Tsukita Loss of the expression of α catenin, the 102 kD cadherin associated protein, in central nervous tissues during development. Dev. Growth Differ. 36 1994 59 71
134. S. Nakagawa M. Takeichi Neural crest cell-cell adhesion controlled by sequential and subpopulation-specific expression of novel cadherins. Development 121 1995 1321 1332
135. E.W. Napolitano K. Venstrom E.F. Wheeler L.F. Reichardt Molecular cloning and characterization of B-cadherin, a novel chicken cadherin. J. Cell Biol. 113 1991 893 905
136. I.S. Näthke L. Hinck J.R. Swedlow J. Papkoff W.J. Nelson Defining steady state interactions and distributions of E-cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol. 125 1994 1341 1352
137. W.J. Nelson Regulation of cell surface polarity from bacteria to mammals. Science 258 1992 948 955
138. +-ATPase, ankyrin, and fodrin in Madin-Darby canine kidney (MDCK) cells: Implications for the biogenesis of epithelial cell polarity. J. Cell Biol. 108 1989 893 902
139. W.J. Nelson E.M. Shore A.Z. Wang R.W. Hammerton Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithelial cells. J. Cell Biol. 110 1990 349 357
140. W.J. Nelson P.J. Veshnock Dynamics of membrane-skeleton (fodrin) organization during development of polarity in Madin-Darby canine kidney epithelial cells. J. Cell Biol. 103 1986 1751 1765
141. + -ATPase and implications for the organization of membrane domains in polarized cells. Nature (London) 328 1987 533 536
142. K.M. Neugebauer K.J. Tomaselli J. Lilien L.F. Reichardt N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro. J. Cell Biol. 107 1988 1177 1187
143. J. Noordermeer J. Kingensmith N. Perrimon R. Nusse dishevelled and armadillo act in the Wingless signalling pathway in Drosophila. Nature (London) 367 1994 80 83
144. A. Nose A. Nagafuchi M. Takeichi Isolation of placental cadherin cDNA: Identification of a novel gene family of cell-cell adhesion molecules. EMBO J. 6 1987 3655 3661
145. A. Nose A. Nagafuchi M. Takeichi Expressed recombinant cadherins mediate cell sorting in model systems. Cell 54 1988 993 1001
146. A. Nose M. Takeichi A novel cadherin cell adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos. J. Cell Biol. 103 1986 2649 2658
147. R. Nusse H. Varmus Wnt genes. Cell 69 1992 1073 1087
148. H. Oda T. Uemura Y. Harada Y. Iwai M. Takeichi A Drosophila homolog of cadherin associated with Armadillo and essential for embryonic cell-cell adhesion. Dev. Biol. 165 1994 716 726
149. H. Oda T. Uemura K. Shiomi A. Nagafuchi S. Tsukita M. Takeichi Identification of a Drosophila Homologue of α-catenin and its association with the armadillo protein. J. Cell Biol. 121 1993 1133 1140
150. D.J. Olson J.L. Christian R.T. Moon Effect of Wnt -1 and related proteins on gap junctional communication in Xenopus embryos. Science 252 1991 1173 1176
151. M. Overduin T.S. Harvey S. Bagby K.I. Tong P. Yau M. Takeichi M. Ikura Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science 267 1995 386 389
152. K. Owaribe J. Kartenbeck E. Rungger-Brandle W.W. Franke Cytoskeletons of retinal pigment epithelial cells: Interspecies differences of expression patterns indicate independence of cell function from the specific complement of cytoskeletal proteins. Cell Tissue Res. 254 1988 301 315
153. T. Oyama Y. Kanai A. Ochiai S. Akimoto T. Oda K. Yanagihara A. Nagafuchi S. Tsukita S. Shibamoto F. Ito M. Takeichi H. Matsuda S. Hirohashi Atruncated β-catenin disrupts the interaction between E-cadherin and α-catenin: A cause of loss of intercellular adhesiveness in human cancer cell lines. Cancer Res. 54 1994 6282 6287
154. M. Ozawa H. Baribault R. Kemler The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8 1989 1711 1717
155. M. Ozawa R. Kemler Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin. J. Cell Biol. 111 1990 1645 1650
156. A.E. Parker G.N. Wheeler J. Arnemann S.C. Pidsley P. Ataliotis C.L. Thomas D.A. Rees A.I. Magee R.S. Buxton Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing. J. Biol. Chem. 266 1991 10438 10445
157. B.A. Parr A.P. McMahon Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature (London) 374 1995 350 353
158. M. Peifer S. Berg A.B. Reynolds A repeating amino acid motif shared by proteins with diverse cellular roles. Cell 76 1994 789 791
159. M. Peifer P.D. McCrea K.J. Green E. Wieschaus B.M. Gumbiner The vertebrate adhesive junction proteins β-catenin and plakoglobin and the Drosophila segmentpolarity gene armadillo form a multigene family with similar properties. J. Cell Biol. 118 1992 681 691
160. M. Peifer S. Orsulic L.-M. Pai J. Loureiro A model system for cell adhesion and signal transduction in Drosophila. Development 1993 Suppl. 1993 163 176
161. M. Peifer S. Orsulic D. Sweeton E. Wieschaus A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis. Development 118 1993 1191 1207
162. M. Peifer L.-M. Pai M. Casey Phosphorylation of the Drosophila adherens junction protein Armadillo: Roles for Wingless signal and Zeste white-3 kinase. Dev. Biol. 166 1995 543 546
163. M. Peifer D. Sweeton M. Casey E. Wieschaus wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 120 1994 369 380
164. M. Peifer E. Wieschaus The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 63 1990 1167 1178
165. N. Peyrieras D. Louvard F. Jacob Characterization of antigens recognized by monoclonal and polyclonal antibodies directed against uvomorulin. Proc. Natl. Acad. Sci. U.S.A. 82 1985 8067 8071
166. P. Piepenhagen W.J. Nelson Defining E-cadherin-associated protein complexes in epithelial cells: Plakoglobin, β- and γ-catenin are distinct components. J. Cell Sci. 104 1993 751 762
167. S.B. Pierce D. Kimelman Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3. Development 121 1995 755 765
168. P.M. Quinton E.M. Wright J.M. Tormey Localization of sodium pumps in the choroid plexus epithelium. J. Cell Biol. 58 1973 724 730
169. B. Ranscht M. Bronner-Fraser T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo. Development 111 1991 15 22
170. B. Ranscht M.T. Dours-Zimmermann T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region. Neuron 7 1991 391 402
171. C. Redies H. Inuzuka M. Takeichi Restricted expression of N- and R-cadherin on neurites of the developing chicken CNS. J. Neurosci. 12 1992 3525 3534
172. C. Redies M. Takeichi Expression of N-cadherin mRNA during development of the mouse brain. Dev. Dynam. 197 1993 26 39
173. C. Redies M. Takeichi N- and R-cadherin expression in the optic nerve of the chicken embryo. Glia 8 1993 161 171
174. v-src, is related to cadherin-binding factors β-catenin, plakoglobin and armadillo. Oncogene 7 1992 2439 2445
175. B. Riggleman P. Schedl E. Wieschaus Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell 63 1990 549 560
176. D.L. Rimm E.R. Koslov P. Kebriaei C.D. Cianci J.S. Morrow (E) α-catenin is an actin binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc. Natl. Acad. Sci. U.S.A 92 1994 8813 8817
177. 2+-dependent cell adhesion. EMBO J. 6 1987 3647 3653
178. L.J. Rizzolo The distribution of Na,K-ATPase in the retinal pigmented epithelium from chicken embryo is polarized in vivo but not in primary cell culture. Exp. Eye Res. 51 1990 435 446
179. L.J. Rizzolo Basement membrane stimulates the polarized distribution of integrins but not the Na,K-ATPase in the retinal pigment epithelium. Cell Regul. 2 1991 939 949
180. E. Rodriguez-Boulan W.J. Nelson Morphogenesis of the polarized epithelial cell phenotype. Science 245 1989 718 725
181. B. Rubinfeld B. Souza I. Albert O. Muller S.H. Chamberlain F.R. Masiarz S. Munemitsu P. Polakis Association of the APC gene product with beta-catenin. Science 262 1993 1731 1734
182. B. Rubinfeld B. Souza I. Albert S. Munemitsu P. Polakis The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin and plakoglobin. J. Biol. Chem. 270 1995 5549 5555
183. M.P. Sacristán D.J. Vestal M.T. Dours-Zimmermann B. Ranscht T-cadherin 2: Molecular characterization, function in cell adhesion, and coexpression with T-cadherin and N-cadherin. J. Neurosci. Res. 34 1993 664 680
184. K. Sano H. Tanihara R.L. Heimark S. Obata M. Davidson T. St. John S. Taketanin S. Suzuki Protocadherins: A large family of cadherin-related molecules in central nervous system. EMBO J. 12 1993 2249 2256
185. R. Schuh D. Vestweber I. Riede M. Ringwald U.B. Eosenberg H. Jackie R. Kemler Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains B1-related segment. Proc. Natl. Acad. Sci. U.S.A. 93 1986 1364 1368
186. M.A. Schwarz K. Owaribe J. Kartenbeck W.W. Franke Desmosomes and hemidesmosomes: Constitutive molecular components. Ann. Rev. Cell Biol. 6 1990 461 491
187. +-ATPase in polarized epithelial cells. Science 260 1993 554 556
188. L. Shapiro A.M. Fannon P.D. Kwong A. Thompson M.S. Lehmann G. Grubel J.-F. Legrand J. Als-Nielsen D.R. Colman W.A. Hendrickson Structural basis of cell-cell adhesion by cadherins. Nature (London) 374 1995 327 337
189. S. Shibamoto M. Hayakawa K. Takeuchi T. Hori K. Miyazawa N. Kitamura K. Johnson M. Wheelock N. Matsuyoshi M. Takeichi F. Ito Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes. J. Cell Biol. 128 1995 949 957
190. S. Shibamoto M. Hayakawa K. Takeuchi T. Hori N. Oku K. Miyazawa N. Kitamura M. Takeichi F. Ito Tyrosine phosphorylation of β-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhesion Commun. 1 1994 295 305
191. K. Shimamura S. Hirano A.P. McMahon M. Takeichi Wnt-1 -dependent regulation of local E-cadherin and αN-catenin expression in the embryonic mouse brain. Development 120 1994 2225 2234
192. K. Shimamura M. Takeichi Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis. Development 116 1992 1011 1019
193. Y. Shimoyama A. Nagafuchi S. Fujita M. Gotoh M. Takeichi S. Tsukita S. Hirohashi Cadherin dysfunction in a human cancer cell line: Possible involvement of loss of α-catenin expression in reduced cell-cell adhesiveness. Cancer Res. 52 1992 5770 5774
194. Y. Shirayoshi K. Hatta M. Hosoda S. Tsunasawa F. Sakiyama M. Takeichi Cadherin cell adhesion molecules with distinct binding specificities share a common structure. EMBO J. 5 1986 2485 2488
195. E.M. Shore W.J. Nelson Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney (MDCK) epithelial cells. J. Biol. Chem. 266 1991 19672 19680
196. E. Siegfried T. Chou N. Perrimon wingless signaling acts through zeste-white 3 , the Drosophila homolog of glycogen synthase kinase-3 , to regulate engrailed and establish cell fate. Cell 71 1992 1167 1179
197. E. Siegfried E.L. Wilder N. Perrimon Components of wingless signalling in Drosophila. Nature (London) 367 1994 76 80
198. S.Y. Sokol J. Klingensmith N. Perrimon K. Itoh Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121 1995 1637 1647
199. B.C. Sorkin W.J. Gallin G.M. Edelman B.A. Cunningham Genes for two calcium-dependent cell adhesion molecules have similar structures and are arranged in tandem in the chicken genome. Proc. Natl. Acad. Sci. U.S.A. 88 1991 11545 11549
200. J.M. Staddon C. Smales C. Schulze F.S. Esch L.L. Rubin P120, a pl20-related protein (p100), and the cadherin/catenin complex. J. Cell Biol. 130 1995 369 381
201. J.R. Stanley Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion. Adv. Immunol. 53 1993 291 325
202. T.S. Stappenbeck E.A. Bornslaeger C.M. Corcoran H.H. Luu M.L.A. Virata K.J. Green Functional analysis of desmoplakin domains: Specification of the interaction with keratin versus vimentin intermediate filament networks. J. Cell Biol. 123 1993 691 705
203. T.S. Stappenbeck K.J. Green The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells. J. Cell Biol. 116 1992 1197 1209
204. T.S. Stappenbeck J.A. Lamb C.M. Corcoran K.J. Green Phosphorylation of the desmoplakin C-terminus negatively regulates its interaction with keratin intermediate filament networks. J. Biol. Chem. 269 1994 29351 29354
205. J. Stappert R. Kemler A short region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Adhes. Commun. 2 1994 319 323
206. K. Stark S. Vainio G. Vassileva A. McMahon Epithelial transformation of metanephric mesenchyme in thedeveloping kidney regulated by Wnt-4. Nature (London) 372 1994 679 683
207. M.S. Steinberg The problem of adhesive selectivity in cellular interactions. M. Locke Cellular Membranes in Development 1964 Academic Press New York 321 366
208. M.S. Steinberg M. Takeichi Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl. Acad. Sci. U.S.A. 91 1994 206 209
209. R.M. Steinberg S.S. Miller Transport and membrane properties of the retinal pigment epithelium. K.M. Zinn M.F. Marmor The Retinal Pigment Epithelium 1979 Harvard University Press Cambridge, Massachusetts 205 225
210. L.K. Su B. Vogelstein K.W. Kinzler Association of the APC tumor suppressor protein with catenins. Science 262 1993 1734 1737
211. S. Suzuki K. Sano H. Tanihara Diversity of the cadherin family: Evidence for eight new cadherins in nervous tissue. Cell Regul. 2 1991 261 270
212. M. Takeichi Functional correlation between cell adhesive properties and some cell surface molecules. J. Cell Biol. 75 1977 464 474
213. M. Takeichi The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis. Development 102 1988 639 655
214. M. Takeichi Cadherins: A molecular family important in selective cell-cell adhesion. Ann. Rev. Biochem. 59 1990 237 252
215. M. Takeichi Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251 1991 1451 1455
216. M. Takeichi Cadherins in cancer: Implications for invasion and metastasis. Curr. Opin. Cell Biol. 5 1993 806 811
217. 2+-dependent sites. Dev. Biol. 87 1981 340 350
218. J.P. Thiery A. Delouvee W.J. Gallin B.A. Cunningham G.M. Edelman Ontogenetic expression of cell adhesion molecules: L-CAM is found in epithelia derived from the three primary germ layers. Dev. Biol. 102 1984 61 78
219. K.R. Thomas M.R. Capecchi Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature (London) 346 1990 847 850
220. K.J. Tomaselli K.M. Neugebauer J.L. Bixby J. Lilien L.F. Reichardt N-cadherin and integrins: Two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces. Neuron 1 1988 33 43
221. P.L. Townes J. Holtfreter Directed movements and selective adhesion of embryonic amphibian cells. J. Exp. Zool. 128 1955 53 118
222. J.P. Trinkaus Mechanisms of morphogenetic movements. R.L.H. De Haan Ursprung Organogenesis 1965 Holt Rinehart and Winston New York 55 104
223. S.M. Troyanovsky L.G. Eshkind R.B. Troyanovsky R.E. Leube W.W. Franke Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage. Cell 72 1993 561 574
224. S.M. Troyanovsky R.B. Troyanovsky L.G. Eshkind V.A. Krutovskikh R.E. Leube W.W. Franke Identification of the plakoglobin-binding domain in desmoglein and its role in plaque assembly and intermediate filament anchorage. J. Cell Biol. 127 1994 151 160
225. S. Tsukita K. Oishi T. Akiyama Y. Yamanashi T. Yamamoto S. Tsukita Specific proto-oncogene tyrosine kinases of src family are enriched in cell-to-cell junctions where the level of tyrosine phosphorylation is elevated. J. Cell Biol. 113 1991 867 879
226. S. Tsukita S. Tsukita A. Nagafuchi S. Yonemura Molecular linkage between cadherins and actin filaments in cell-cell adherens junction. Curr. Opin. Cell Biol. 4 1992 834 839
227. N. Uchida K. Shimamura S. Miyatani N.G. Copeland D.J. Gilbert N.A. Jenkins M. Takeichi Mouse αN-catenin: Two isoforms, specific expression in the nervous system, and chromosomal localization of the gene. Dev. Biol. 163 1994 75 85
228. R. Vassar P.A. Coulombe L. Degenstein K. Alpers E. Fuchs Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell 64 1991 365 380
229. D. Vestal B. Ranscht Glycosyl phosphatidylinositol-anchored T-cadherin mediates calcium-dependent, homophilic cell adhesion. J. Cell Biol. 119 1992 451 461
230. D. Vestweber A. Gossler K. Boller R. Kemler Expression and distribution of the cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev. Biol. 124 1987 451 456
231. D. Vestweber R. Kemler Identification of a putative cell adhesion domain of uvomorulin. EMBO J. 4 1985 3393 3398
232. D. Vestweber R. Kemler Rabbit antiserum against a purified surface glycoprotein decompacts mouse preimplantation embryos and reacts with specific adult tissues. Exp. Cell Res. 152 1984 169 178
233. D. Vestweber R. Kemler Some structural and functional aspects of the cell adhesion molecule uvomorulin. Cell. Differ. 15 1984 269 273
234. D. Vestweber R. Kemler P. Ekblom Cell-adhesion molecule uvomorulin during kidney development. Dev. Biol. 112 1985 213 221
235. K. Vleminckx L. Vakaet M. Mareel W. Fiers F. Van Roy Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66 1991 107 120
236. T. Volberg B. Geiger R. Dror Y. Zick Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells. Cell Regul. 2 1991 105 120
237. F.S. Walsh P. Doherty Factors regulating the expression and function of calcium-independent cell adhesion molecules. Curr. Opin. Cell Biol. 5 1993 791 796
238. F.S. Walsh P. Doherty Second messengers underlying cell-contact-dependent axonal growth stimulated by transfected N-CAM, N-cadherin, or L1. Cold Spring Harbor Symp. Quant Biol. 57 1992 431 440
239. A.Z. Wang G.K. Ojakian W.J. Nelson Steps in the morphogensis of a polarized epithelium. I. Uncoupling the roles of cell-cell and cell substratum contact in establishing plasma membrane polarity in multicellular epithelial (MDCK) cysts. J. Cell Sci. 95 1990 137 151
240. M. Watabe K. Matsumoto T. Nakamura M. Takeichi Effect of hepatocyte growth factor on cadherin-mediated cell-cell adhesion. Cell Struct. Fund. 18 1993 117 124
241. M. Watabe A. Nagafuchi S. Tsukita M. Takeichi Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J. Cell Biol. 127 1994 247 256
242. F.M. Watt Involucrin and other markers of keratinocyte terminal differentiation. J. Invest Dermatol. 81 1983 100S 103S
243. F.M. Watt H. Green Stratification and terminal differentiation of cultured epidermal cells. Nature (London) 295 1982 434 436
244. W. Weis Cadherin structure: A revealing zipper. J. Struct. 3 1995 425 427
245. M.J. Wheelock P.J. Jensen Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin. J. Cell Biol. 117 1992 415 425
246. D.F. Woods P.J. Bryant Apical junctions and cell signalling in epithelia. J. Cell Sci. Suppl. 17 1993 171 181
247. E.M. Wright Mechanisms of ion transport across the choroid plexus. J. Physiol. 226 1972 545 571
248. S. Yonemura M. Itoh A. Nagafuchi S. Tsukita Cell-to-cell adherens junction formation and actin filament organization: Similarities and differences between nonpolarized fibroblasts and polarized epithelial cells. J. Cell Sci. 108 1995 127 142