Embryonic heart and skin defects in mice lacking plakoglobin

Developmental Biology

Volumn 180, Issue 2, 1996, Pages 780-785

  Bierkamp, Christiane ^a   McLaughlin, K John ^a   Schwarz, Heinz ^b   Huber, Otmar ^a   Kemler, Rolf ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLAKOGLOBIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DESMOSOME; ELECTRON MICROSCOPY; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMOLYSIS; GENE TARGETING; HYPERKERATOSIS; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; SKIN DEFECT; TRANSGENIC MOUSE;

EID: 0030589631     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1996.0346     Document Type: Article

References (17)

1. Aberle, H., Schwartz, H., and Kemler, R. (1996). Cadherin-catenin complex: Protein interactions and their implications for cadherin function. J Cell. Biochem. 61, 514-523.
2. Allen, E., Yu, Q.-C., and Fuchs, E. (1996). Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation and epidermal differentiation. J. Cell Biol. 133, 1367-1382.
3. Bale, S. J., Compton, J. G., and DiGiovanna, J. J. (1993). Epidermolytic hyperkeratosis. Semin. Dermatol. 12, 202-209.
4. Behrens, J., von Kries, J. P., Kahl, M., Bruhn, L., Wedlich, D., Grosschedl, R., and Birchmeier, W. (1996). Functional interaction of β-catenin with the transcription factor LEF-1. Nature 382, 638-642.
5. Butz, S., and Larue, L. (1995). Expression of catenins during mouse embryonic development and in adult tissues. Cell Adhes. Commun. 3, 337-352.
6. Butz, S., Stappert, J., Weissig, H., and Kemler, R. (1992). Plakoglobin and β-catenin: Distinct but closely related. Science 257, 1142-1144.
7. Cheng, J., Syder, A. J., Yu, Q.-C., Letai, A., Paller, A. S., and Fuchs, E. (1992). The genetic basis of epidermolytic hyperkeratosis: A disorder of differentiation-specific epidermal keratin genes. Cell 70, 811-819.
8. Cowin, P., Kapprel, H. P., Franke, W. W., Tamkun, J., and Hynes, R. O. (1986). Plakoglobin: A protein common to different kinds of intercellular adhering junctions. Cell 46, 1063-1073.
9. Franke, W. W., Goldschmidt, M. D., Zimbelmann, R., Mueller, H. M., Schiller, D. L., and Cowin, P. (1989). Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein. Proc. Natl. Acad. Sci. USA 86, 4027-4031.
10. Haegel, H., Larue, L., Ohsugi, M., Fedorov, L., Herrenknecht, K., and Kemler, R. (1995). Lack of β-catenin affects mouse development at gastrulation. Development 121, 3529-3537.
11. Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G., and Kemler, R. (1996). Nuclear localization of β-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-11.
12. Karnovsky, A., and Klymkowsky, M. W. (1995). Anterior axis duplication in Xenopus induced by the overexpression of the cadherin-binding protein plakoglobin. Proc. Natl. Acad. Sci. USA 92, 4522-4526.
13. Mathur, M., Goodwin, L., and Cowin, P. (1994). Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin. J. Biol. Chem. 269, 14075-14080.
14. Schwarz, H., Müller-Schmidt, A., and Hoffman, W. (1993). Ultrastructural localization of ependymins in the endomeninx of the brain of the rainbow trout: Possible association with collagen fibrils of the extracellular matrix. Cell Tissue Res. 273, 417-425.
15. Troyanovsky, S. M., Eshkind, L. G., Troyanovsky, R. B., Leube, R. E., and Franke, W. W. (1993). Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage. Cell 72, 561-574.
16. Troyanovsky, S. M., Troyanovsky, R. B., Eshkind, L. G., Krutovskikh, V. A., Leube, R. E., and Franke, W. W. (1994a). Identification of the plakoglobin-binding domain in desmoglein and its role in plaque assembly and intermediate filament anchorage. J. Cell Biol. 127, 151-160.
17. Troyanovsky, S. M., Troyanovsky, R. B., Eshkind, L. G., Leube, R. E., and Franke, W. W. (1994b). Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation. Proc. Natl. Acad. Sci. USA 91, 10790-10794.