Controlling Insulin-Like Growth Factor Activity and the Modulation of Insulin-Like Growth Factor Binding Protein and Receptor Binding

Journal of Dairy Science

Volumn 81, Issue 6, 1998, Pages 1790-1800

  McCusker, R H ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b 205 Meat Science Lab   (United States)

Author keywords

Binding protein; Insulin like growth factor; Receptor; Zinc

Indexed keywords

INSULIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

ANIMAL; ANIMAL FOOD; CELL DIVISION; COMPARATIVE STUDY; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; CELL DIVISION; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; RECEPTORS, SOMATOMEDIN;

EID: 0032085138     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(98)75748-0     Document Type: Article

References (90)

1. Andress, D. L., S. M. Loop, J. Zapf, and M. C. Kiefer. 1993. Carboxy-truncated insulin-like growth factor binding protein-5 stimulates mitogenesis in osteoblast-like cells. Biochem. Biophys. Res. Commun. 195:25-30.
2. Bai, J.P.F. 1995. The involvement of cytosolic chymotrypsin-like, trypsin-like, and cucumsin-like activities in degradation of insulin and insulin-like growth factor I by epithelial tissues. J. Pharm. Pharmacol. 47:674-677.
3. Baserga, R., A. Hongo, M. Rubini, M. Prisco, and B. Valentinis. 1997. The IGF-I receptor in cell growth, transformation and apoptosis. Biochem. Biophys. Acta Rev. Cancer 1332: F105-F126.
4. Bauer, M., and N. Parvizi. 1996. Pulsatile and diurnal secretion of GH and IGF-I in the chronically catheterized pig fetus. J. Endocrinol. 149:125-133.
5. Baxter, R. C. 1995. Insulin-like growth factor binding proteins as glucoregulators. Metabolism 44:12-17.
6. Beguinot, F., C. R. Kahn, A. C. Moses, and R. J. Smith. 1986. The development of insulin receptors and responsiveness is an early marker of differentiation in the muscle cell line L6. Endocrinology 118:446-455.
7. Benito, M., A. M. Valverde, and M. Lorenzo. 1996. IGF-I: a mitogen also involved in differentiation processes in mammalian cells. Int. J. Biochem. Cell Biol. 28:499-510.
8. Binoux, M., and P. Hossenlopp. 1988. Insulin-like growth factor (IGF) and IGF-binding proteins: comparison of human serum and lymph. J. Clin. Endocrinol. Metab. 67:509-514.
9. Blundell, T. L., S. Bedarkar, E. Rinderknecht, and R. E. Humbel. 1978. Insulin-like growth factor: a model for tertiary structure accounting for immunoreactivity and receptor binding. Proc. Natl. Acad. Sci. USA 75:180-184.
10. Bourner, M. J., W. H. Busby, N. R. Siegel, G. G. Krivi, R. H. McCusker, and D. R. Clemmons. 1992. Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): comparison of its structural and functional properties with IGFBP-1. J. Cell. Biochem. 48:215-226.
11. Brandaoneto, J., V. Stefan, B. B. Mendonca, W. Bloise, and A.V.B. Castro. 1995. The essential role of zinc in growth. Nutr. Res. 15:335-358.
12. Camacho-Hubner, C., W. H. Busby, R. H. McCusker, G. Wright, and D. R. Clemmons. 1992. Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion. J. Biol. Chem. 267:11949-11956.
13. Camacho-Hubner, C., R. H. McCusker, and D. R. Clemmons. 1991. Secretion and biological actions of insulin-like growth factor binding proteins in two human tumor-derived cell lines in vitro. J. Cell. Physiol. 148:281-289.
14. Cascieri, M. A., and M. L. Bayne. 1994. Analysis of the interaction of insulin-like growth factor I (IGF-I) analogs with the IGF-I receptor and IGF-binding proteins. Horm. Res. 41:80-86.
15. Chan, S. J., Q. P. Cao, and D. F. Steiner. 1990. Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus. Proc. Natl. Acad. Sci. USA 87:9319-9323.
16. Chen, J. C., Z. M. Shao, M. S. Sheikh, A. Hussain, D. LeRoith, C. T. Roberts, and J. A. Fontana. 1994. Insulin-like growth factor-binding protein enhancement of insulin-like growth factor-I (IGF-I)-mediated DNA synthesis and IGF-I binding in a human breast carcinoma cell line. J. Cell. Physiol. 158:69-78.
17. Clemmons, D. R., M. A. Cascieri, C. Camacho-Hubner, R. H. McCusker, and M. L. Bayne. 1990. Discrete alterations of the IGF-I molecule that alter its affinity for IGF binding proteins result in changes in bioactivity. J. Biol. Chem. 260: 12210-12216.
18. Clemmons, D. R., M. Dehoff, R. H. McCusker, R. Elgin, and W. Busby. 1988. The role of insulin-like growth factor I in the regulation of growth. J. Anim. Sci. 65(Suppl. 2):168-179.
19. Clemmons, D. R., and L. I. Gardner. 1990. A factor contained in plasma is required for IGF binding protein-1 to potentiate the effect of IGF-I on smooth muscle cell DNA synthesis. J. Cell. Physiol. 145:129-135.
20. Clemmons, D. R., V.K.M. Han, R. G. Elgin, and A. J. D'Ercole. 1987. Alterations in the synthesis of a fibroblast surface associated 35 K protein modulates the binding of somatomedin-C/ insulin-like growth factor I. Mol. Endocrinol. 1:339-347.
21. Conover, C. A. 1991. Glycosylation of insulin-like growth factor binding protein-3 (IGFBP-3) is not required for potentiation of IGF-I action: evidence for processing of cell-bound IGFBP-3. Endocrinology 129:3259-3268.
22. Conover, C. A., M. Ronk, F. Lombana, and D. R. Powell. 1990. Structural and biological characterization of bovine insulin-like growth factor binding protein-3. Endocrinology 127:2795-2803.
23. Coolican, S. A., D. S. Samuel, D. Z. Ewton, F. J. Mcwade, and J. R. Florini. 1997. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J. Biol. Chem. 272:6653-6662.
24. DeVroede, M. A., L.Y.H. Tseng, P. G. Katsoyannis, S. P. Nissley, and M. M. Rechler. 1986. Modulation of insulinlike growth factor I binding to human fibroblast monolayer cultures by insulin-like growth factor carrier proteins released to the incubation media. J. Clin. Invest. 77:602-613.
25. Dieguez, C., and F. F. Casanueva. 1995. Influence of metabolic substrates and obesity on growth hormone secretion. Trends Endocrinol. Metab. 6:55-59.
26. DiGirolamo, M., S. Eden, G. Enberg, O. Isaksson, P. Lonnroth, K. Hall, and U. Smith. 1986. Specific binding of human growth hormone but not insulin-like growth factors by human adipocytes. FEBS Lett. 205:15-19.
27. Donaghue, K. C., T. M. Badger, W. J. Millard, L. S. Frisch, and W. E. Russell. 1990. Absence of ultradian rhythm or diurnal variation in insulin-like growth factor-I in rats. Neuroendocrinology. 52:1-8.
28. Duchamp, C., K. A. Burton, A. Geloen, and M. J. Dauncey. 1997. Transient upregulation of IGF-I gene expression in brown adipose tissue of cold-exposed rats. Am. J. Physiol. 35: E453-E460.
29. Ewton, D. Z., and S. L. Falen. 1987. The type II insulin-like growth factor (IGF) receptor has low affinity for IGF-I analogs: pleiotropic actions of IGFs on myoblasts are apparently mediated by the type I receptor. Endocrinology 120:115-123.
30. Florini, J. R., D. Z. Ewton, M. J. Evinger-Hodges, S. L. Falen, R. L. Lau, J. F. Regan, and B. M. Vertel. 1984. Stimulation and inhibition of myoblast differentiation by hormones. In Vitro (Rockville) 20:942-958.
31. Froesch, E. R., and J. Zapf. 1985. Insulin-like growth factors and insulin: comparative aspects. Diabetologia 28:485-493.
32. Furlanetto, R. W. 1988. Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells. Endocrinology 122:2044-2053.
33. Giudice, L. C. 1995. IGF binding protein-3 protease regulation: how sweet it is! J. Clin. Endocrinol. Metab. 80:2279-2281.
34. GoodmanGruen, D., and E. BarrettConnor. 1997. Epidemiology of insulin-like growth factor-I in elderly men and women-the Rancho Bernardo study. Am. J. Epidemiol. 145:970-976.
35. Gruppuso, P. A., T. D. Walker, and P. A. Carter. 1991. Ontogeny of hepatic type I insulin-like growth factor receptors in the rat. Pediatr. Res. 29:226-230.
36. Guyton, A. C. 1971. Pages 872-885 in Textbook of Medical Physiology. 4th ed. W. B. Saunders Co., Philadelphia, PA.
37. Hickman, J., and A. McElduff. 1989. Insulin promotes growth of the culture rat osteosarcoma cell line UMR-106-01: an osteoblast-like cell. Endocrinology 124:701-706.
38. Hintz, R. L., A. V. Thorsson, G. Enberg, and K. Hall. 1984. IGF-II binding on human lymphoid cells: demonstration of a common high affinity receptor for insulin like peptides. Biochem. Biophys. Res. Commun. 118:774-782.
39. Hofmann, C., M. F. White, and J. Whittaker. 1989. Human insulin receptors expressed in insulin-insensitive mouse fibroblasts couple with extant cellular effector systems to confer insulin sensitivity and responsiveness. Endocrinology 124: 257-264.
40. Holly, J.M.P., C. P. Smith, D. B. Dunger, J. A. Edge, R. A. Biddlecombe, A.J.K. Williams, R. Howell, T. Chard, M. O. Savage, L. H. Rees, and J.A.H. Wass. 1989. Levels of the small insulin-like growth factor-binding protein are strongly related to those of insulin in prepubertal and pubertal children but only weakly so after puberty. J. Endocrinol. 121:383-387.
41. Hossner, K. L., R. H. McCusker, and M. V. Dodson. 1997. Insulin-like growth factors and their binding proteins in domestic animals. Anim. Sci. 64:1-15.
42. James, D. E., A. Zorzano, M. Boni-Schnetzler, R. A. Nemenoff, A. P. Powers, P. F. Pilch, and N. B. Ruderman. 1986. Intrinsic differences of insulin receptor kinase activity in red and white muscle. J. Biol. Chem. 261:14939-14944.
43. Jones, J. I., and D. R. Clemmons. 1995. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16:3-34.
44. Jones, J. I., A. J. D'Ercole, C. Camacho-Hubner, and D. R. Clernmons. 1991. Phosphorylation of insulin-like growth factor (IGF)-binding protein-1 in cell culture and in vivo: effects on affinity for IGF-I. Proc. Natl. Acad. Sci. USA 88:7481-7485.
45. Jyung, R. W., T. A. Mustoe, W. H. Busby, and D. R. Clemmons. 1994. Increased wound-breaking strength induced by insulin-like growth factor I in combination with insulin-like growth factor binding protein-1. Surgery (St. Louis) 115:233-239.
46. Kanzaki, M., M. Hattori, and I. Kojima. 1996. Growth or differentiation: determination by FSH of the action of insulin-like growth factor-I in cultured rat granulosa cells. Endocr. J. 43:15-23.
47. Kiess, W., C. Terry, W. H. Burgess, B. Linder, W. Lopaczynski, and P. Nissley. 1994. Insulin-like growth factor-II is a substrate for dipeptidylpeptidase I (cathepsin C) - biological properties of the product. Eur. J. Biochem. 226:179-184.
48. Klip, A., G. Li, and D. Walker. 1983. Insulin binding to differentiating muscle cells in culture. Can. J. Biochem. Cell Biol. 61: 644-649.
49. Lee, C. Y., D. W. Hunt, S. L. Gray, and D. M. Henricks. 1991. Secretory patterns of growth hormone and insulin-like growth factor-I during peripubertal period in intact and castrate male cattle. Dom. Anim. Endocrinol. 8:481-489.
50. LeRoith, D., H. Werner, D. Beitnerjohnson, and C. T. Roberts. 1995. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16:143-163.
51. Li, Y. M., D. H. Schacher, Q. Liu, S. Arkins, N. Rebeiz, R. H. McCusker, R. Dantzer, and K. W. Kelley. 1997. Regulation of myeloid growth and differentiation by the insulin-like growth factor I receptor. Endocrinology 138:362-368.
52. Macdougald, O. A., and M. D. Lane. 1995. Transcriptional regulation of gene expression during adipocyte differentiation. Annu. Rev. Biochem. 64:345-373.
53. Martin, J. L., M. Ballesteros, and R. C. Baxter. 1992. Insulin-like growth factor-I (IGF-I) and transforming growth factor-beta 1 release IGF-binding protein-3 from human fibroblasts by different mechanisms. Endocrinology 131:1703-1710.
54. McCusker, R. H., W. H. Busby, C. Camacho-Hubner, and D. R. Clemmons. 1989. Secretion of insulin-like growth factor binding proteins (IGF-BPs) by muscle cells in vitro. Pages 257-265 in Insulin-like Growth Factor Binding Proteins. S.L.S, Drop and R. H. Hintz, ed. Excerpta Med. Elsevier Sci. Publ. B.V., Amsterdam, The Netherlands.
55. McCusker, R. H., W. H. Busby, M. H. Dehoff, C. Camacho-Hubner, and D. R. Clemmons. 1991. Insulin-like growth factor (IGF) binding to cell monolayers is directly modulated by the addition of IGF-binding proteins. Endocrinology 129:939-949.
56. McCusker, R. H., C. Camacho-Hubner, M. L. Bayne, M. A. Cascieri, and D. R. Clemmons. 1990. Insulin-like growth factor (IGF) binding to human fibroblast and glioblastoma cells: the modulating effect of cell released IGF binding proteins (IGFBPs). J. Cell. Physiol. 144:244-253.
57. McCusker, R. H., and D. R. Clemmons. 1992. The insulin-like growth factor binding proteins: structure and biological functions. Pages 110-150 in The Insulin-Like Growth Factor Binding Proteins: Structure and Biological Functions. P. N. Schofield, ed. Oxford Univ. Press, Oxford, United Kingdom.
58. McCusker, R. H., and D. R. Clemmons. 1997. Use of lanthanum to accurately quantify insulin-like growth factor binding to proteins on cell surfaces. J. Cell. Biochem. 66:256-267.
59. 2-LISN muscle cells. J. Cell. Physiol. 176:(August).
60. McCusker, R. H., P. J. Wangsness, L. C. Griel, and J. F. Kavanaugh. 1985. Effects of feeding, fasting and refeeding on growth hormone and insulin in obese pigs. Physiol. Behav. 35: 383-388.
61. Mohan, S., Y. Nakao, Y. Honda, E. Landale, U. Leser, C. Dony, K. Lang, and D. J. Baylink. 1995. Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells. J. Biol. Chem. 270:20424-20431.
62. Morrione, A., B. Valentinis, S. Q. Xu, G. Yumet, A. Louvi, A. Efstratiadis, and R. Baserga. 1997. Insulin-like growth factor II stimulates cell proliferation through the insulin receptor. Proc. Natl. Acad. Sci. USA 94:3777-3782.
63. Murphy, L. J., P. Molnar, X. Lu, and H. Huang. 1995. Expression of human insulin-like growth factor-binding protein-3 in transgenic mice. J. Mol. Endocrin. 15:293-303.
64. Oh, Y. M., S. R. Nagalla, Y. Yamanaka, H. S. Kim, E. Wilson, and R. G. Rosenfeld. 1996. Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7- recombinant human mac25 protein specifically binds IGF-I and II. J. Biol. Chem. 271:30322-30325.
65. Orlowski, C. C., S. D. Chernausek, and R. Akeson. 1989. Actions of insulin-like growth factor-I on the B104 neuronal cell line: effects on cell replication, receptor characteristics, and influence of secreted binding protein on ligand binding. J. Cell Physiol. 139:469-476.
66. Park, J.H.Y., R. H. McCusker, H. Mohammadpour, D. J. Blackwood, M. Hrbek, and J. A. Vanderhoof. 1994. Dexamethasone inhibits mucosal adaptation after small bowel resection. Am. J. Physiol. 266:G497-G503.
67. Park, J.H.Y., R. H. McCusker, J. A. Vanderhoof, H. Mohammadpour, R. F. Harty, and R. G. MacDonald. 1992. Secretion of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 by intestinal epithelial (IEC-6) cells: implications for autocrine growth regulation. Endocrinology 131:1359-1368.
68. Parrizas, M., A. R. Saltiel, and D. LeRoith. 1997. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J. Biol. Chem. 272:154-161.
69. Quinn, L. S., M. Ehsan. B. Steinmetz, and M. Kaleko. 1993. Ligand-dependent inhibition of myoblast differentiation by overexpression of the type-1 insulin-like growth factor receptor. J. Cell. Physiol. 156:453-461.
70. Rajkumar, K., D. Barron, M. S. Lewitt, and L. J. Murphy. 1995. Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice. Endocrinology 136: 4029-4034.
71. Randazzo, P. A., V. A. Morey, A. K. Polishook, and L. Jarett. 1990. Characterization of the growth of murine fibroblasts that express human insulin receptors. I. The effect of insulin in the absence of other growth factors. Exp. Cell Res. 190:25-30.
72. Rodriguezarnao, J., J. P. Miell, and R.J.M. Ross. 1993. Influence of thyroid hormones on the GH-IGF-I axis. Trends Endocrinol. Metab. 4:169-173.
73. Rubin, R., and R. Baserga. 1995. Insulin-like growth factor-I receptor: its role in cell proliferation, apoptosis, and tumorigenicity. Lab. Invest. 73:311-331.
74. Rubini, M., H. Werner, E. Gandini, C. T. Roberts, D. LeRoith, and R. Baserga. 1994. Platelet-derived growth factor increases the activity of the promoter of the insulin-like growth factor-1 (IGF-1) receptor gene. Exp. Cell Res. 211:374-379.
75. Rutter, W. J. 1991. Evolution and significance of IGF functions. Pages 541-554 in Modern Concepts of Insulin-like Growth Factors. E. M. Spencer, ed. Elsevier, New York, NY.
76. Sackett, R. L., and R. H. McCusker. 1998. Multivalent cations depress ligand binding to cell-associated insulin-like growth factor binding protein-5 on human glioblastoma cells. Endocrinology 139:1943-1951.
77. Sackett, R. L., and R. H. McCusker. 1998. Multivalent cations depress ligand affinity of insulin-like growth factor binding protein-3 and 5 on human GM-10 fibroblast cell surfaces. J. Cell. Biochem. 69:364-375.
78. Sasaoka, T., M. Ishiki, T. Sawa, H. Ishihara, Y. Takata, T. Imamura, I. Usui, J. M. Olefsky, and M. Kobayashi. 1996. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways. Endocrinology 137: 4427-4434.
79. Schmid, C., J. Rutishauser, I. Schlapfer, E. R. Froesch, and J. Zapf. 1991. Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF-I-stimulation of osteoblasts: control of IGF signaling to bone cells by IGFBP-3-specific proteolysis? Biochem. Biophys. Res. Commun. 179: 579-585.
80. Shimasaki, S., and N. Ling. 1991. Identification and molecular characterization of insulin-like growth factor binding proteins (GFBP-1,-2,-3.-4,-5 and -6). Prog. Growth Factor Res. 3: 243-266.
81. Simpson, E. 1984. Growth factors which affect bone. Trends Biochem. Sci. 9:527-530.
82. Standaert, M. L., S. D. Schimmel, and R. J. Pollet. 1984. The development of insulin receptors and responses in the differentiating nonfusing cell line BC3H-1. J. Biol. Chem. 259: 2337-2345.
83. Stewart, C.E.H., and P. Rotwein. 1996. Growth, differentiation, and survival: Multiple physiological functions for insulin-like growth factors. Physiol. Rev. 76:1005-1026.
84. Thissen, J. P., J. M. Ketelslegers, and L. E. Underwood. 1994. Nutritional regulation of the insulin-like growth factors. Endoer. Rev. 15:80-101.
85. Thrailkill, K., T. Quattrin, L. Baker, J. Litton, K. Dwigun, M. Rearson, M. Poppenheimer, D. Kotlovker, D. Giltinan, N. Gesundheit, and P. Martha. 1997. Dual hormonal replacement therapy with insulin and recombinant human insulin-like growth factor (IGF)-I in insulin-dependent diabetes mellitus: Effects on the growth hormone/IGF/IGF-binding protein system. J. Clin. Endocrinol. Metab. 82:1181-1187.
86. Underwood, L. E., J. P. Thissen, S. Lemozy, J. M. Ketelslegers, and D. R. Clemmons. 1994. Hormonal and nutritional regulation of IGF-I and its binding proteins. Horm. Res. 42:145-151.
87. Werner, H., and D. LeRoith. 1995. Insulin-like growth factor I receptor: structure, signal transduction, and function. Diabetes Rev. 3:28-36.
88. Yang, H. C., and A. B. Pardee. 1986. Insulin-like growth factor I regulation of transcription and replicating enzyme induction necessary for DNA synthesis. J. Cell. Physiol. 127:410-416.
89. Zapf, J., and E. R. Froesch. 1986. Insulin-like growth factors/ somatomedins: structure, secretion, biological actions and physiological role. Horm. Res. 24:121-130.
90. Zapf, J., C. H. Schmid, and E. R. Froesch. 1984. Biological and immunological properties of insulin-like growth factors (IGF) I and II. Clin. Endocrinol. Metab. 13:3-30.