Progression of Alzheimer histopathological changes

Acta Neurologica Belgica

Volumn 98, Issue 2, 1998, Pages 180-185

  Duyckaerts, Charles ^a,c   Colle, Marie Anne ^a   Dessi, Frédéric ^a   Piette, François ^b   Hauw, Jean Jacques ^a  

^a Lab Neuropathologie R Escourolle   (France)

^b HÔPITAL CHARLES FOIX   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; NERVE PROTEIN; TAU PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL TRIAL; DISEASE COURSE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; PATHOLOGY; PROSPECTIVE STUDY;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; NERVE TISSUE PROTEINS; PROSPECTIVE STUDIES; TAU PROTEINS;

EID: 0032084986     PISSN: 03009009     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. BANCHER C., JELLINGER K. A. Neurofibrillary predominant form of Alzheimer's disease : a rare subtype in very old subjects. Acta Neuropaihol. (Berl.), 1994, 84 : 565-570.
2. BARELLI H., LEBEAU A., et al. Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides : their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases. Mol Med., 1997, 695-707.
3. BLESSEO G., TOMLINSON B. E., ROTH M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Brit. J. Psychiat., 1968, 114: 797-811.
4. BRAAK H., BRAAK E. Neuropil threads occur in dendrites of/angle-bearing nerve cells. Neuropathol. Appl. Neurobiol., 1988, 14 : 39-44.
5. BRAAK H., BRAAK E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berlin), 1991, 82 : 239-259.
6. BRAAK H., BRAAK E., GRUNDKE-IQBAL I., IQBAL K. Occurence of neuropil threads in the senile human brain and in Alzheimer's disease. A 3rd location of paired helical filaments outside of neurofilament tangles and neuritic plaques. Neurosci. Lett., 1986, 65 : 351-355.
7. BRION J. P., PASSAREIRO H., NUNEZ J., FLAMENT-DURAND J. Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofibrillaire de la maladie d'Alzheimer. Arch. Biol. (Brux.), 1985, 95 : 229-235.
8. BROOKS W. S., MARTINS R. N., J. D. V., NICHOLSON G. A., SCHOFIELD P. R., KWOK J. B., FISHER C., YEUNG L. U., VAN BROECKHOVEN C. A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. Neurosci. Lett., 1995. 199 : 183-186.
9. CHARTIER-HARLIN M. C., CRAWFORD F., et al. Earlyonset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature, 1991, 353 : 844-846.
10. CITRON M., WESTAWAY D., et al. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nature Medicine, 1997, 3 : 67-72.
11. CLINTON J., BLACKMAN S. E., ROYSTON M. C., ROBERTS G. W. Differential synaptic loss in the cortex in Alzheimer's disease : a study using archival material. Neuroreport, 1994, 5 : 497-500.
12. DELAÈRE P., DUYCKAERTS C., BRION J. P., POULAIN V., HALW J.-J. Tau, paired helical filaments and amyloid in the neocortex : a morphometric study of 15 cases with graded intellectual status in aging and senile dementia of Alzheimer type. Acta Neuropathol., 1989, 77 : 645-653.
13. DELAÈRE P., DUYCKAERTS C., HE Y., PIETTE F., HAUW J.-J. Subtypes and differential laminar distributions of βA4 deposits in Alzheimer's disease : relationship with the intellectual status of 26 cases. Acta Neuropathol., 1991, 81 : 328-335.
14. DELAÈRE P., DUYCKAERTS C., MASTERS C., PIETTE F., HAUW J.-J. Large amounts of neocortical βA4 deposits without Alzheimer changes in a nondemented case. Neurosci. Lett., 1990, 116 : 87-93.
15. DESSI F., COLLE M. A., HAUW J.-J., DUYCKAERTS C. Accumulation of SNAP-25 immunoreactive material in axons of Alzheimer's disease. Neuro Report, 1997, 8 : 3685-3689.
16. DICKSON D. Qualitative differences between senile plaques (SP) in pathological aging (PA) and Alzheimer's disease. Brain Pathol, 1997, 7 : 1054 (abstract).
17. DICKSON D. W., CRYSTAL H. A., MATTIACE L. A., MASUR D. M., BLAU A. D., DAVIES P., YEN S. H., ARONSON M. K. Identification of normal and pathological aging in prospectively studied nondemented elderly humans. Neurobiol. Aging, 1991, 13 : 179-189.
18. DUFF K., ECKMAM C., et al. Increased amyloid-b42(43) brains of mice expressing mutant presenilin 1. Nature. 1996, 383 : 710-713.
19. DUYCKAERTS C., BENNECIB M., GRIGNON Y., UCHIHARA T., HE Y, PIETTE F, HAUW J.-J. Modeling the relation between neurofibrillary tangles and intellectual status. Neurobiol. Aging, 1997, 18 : 267-273.
20. DUYCKAERTS C., COLLE M. A., SEILHEAN D., HAUW J.-J. La spongiose laminaire du gyrus denté : un signe de désafférentation observé dans la maladie d'Alzheimer. De la neurophysiologie à la maladie d'Alzheimer. Bessern J. M., Bassant M.-H., Calvino B., Epelbaum J., Forette F., Lamour Y., Pierrot-Desseilligny C. et Christen Y. Marseille, Solal, 1997.
21. DUYCKAERTS C., COLLE M. A., SEILHEAN D., HAUW J.-J. Laminar spongiosis of the dentate gyrus : a sign of disconnection, present in cases of Alzheimer disease. Acta Neuropathol. (in press).
22. DUYCKAERTS C., DELAÈRE P., POULAIN V., BRION J. P., HAUW J.-J. Does amyloid precede paired helical filaments in the senile plaque ? A study of 15 cases with graded intellectual status in aging and Alzheimer disease. Neurosci. Lett., 1988, 91 : 354-359.
23. DUYCKAERTS C., GODEFROY G., HAUW J.-J. Evaluation of neuronal numerical density by Dirichlet tessellation. J. Neurosci. Meth., 1994, 51 : 47-69.
24. DUYCKAERTS C., HAUW J.-J. Diagnosis and staging of Alzheimer disease. Neurobiol. Ageing, 1997, 18, S4 : S33-S42.
25. DUYCKAERTS C., HAUW J.-J., BASTENAIRE F., PIETTF F., POULAIN C., RAINSARD V., JAVOY-AGID F., BERIHAUX P. Laminar distribution of neocortical plaques in senile dementia of the Alzheimer type. Acta Neuropath. (Berlin), 1986, 70 : 249-256.
26. DUYCKAERTS C., HAUW J.-J., PIETTE F., RAINSARD C., POULAIN V., BERTHAUX P., ESCOUROLLE R. Cortical atrophy in senile dementia of the Alzheimer type is mainly due to a decrease in cortical length. Acta Neuropathol (Berl), 1985, 66 : 72-74.
27. DUYCKAERTS C., KAWASAKI H., DELAÈRE P., RAINSARD C., HAUW J.-J. Fiber disorganization in the neocortex of patients with senile dementia of the Alzheimer type. Neuropath. Appl. Neurobiol., 1989, 15 : 233-247.
28. GAMES D., ADAMS D., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F b-amyloid precursor protein. Nature, 1995, 373 : 523-527.
29. GOMEZ-ISLA T., PRICE J. L., MCKEEL D. W., MORRIS J. C., GROWDON J. H., HYMAN B. T. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J. Neurosci., 1996, 16 : 4491-4500.
30. GRIGNON Y., DUYCKAERTS C., BENNECIB M., HAUW J.-J. Cytoarchitectonic alterations in supramarginal gyrus of late onset Alzheimer's disease. Acta Neuropathol. 1998, 95 : 395-406.
31. HAUW J.-J., SEILHEAN D., PIETTE F, UCHIHARA T., DUYCKAERTS C. Les lésions de la maladie d'Alzheimer : de la morphologie à la biologie cellulaire. Bull. Acad. Natl. Med., 1996, 180: 1687-1701.
32. HAUW J.-J., UCHIHARA T., HE Y., SEILHEAN D., PIETTE F., DUYCKAERTS C. The time course of lesions in the neocortex in ageing and Alzheimer disease. Alzheimer's disease : biology, diagnosis and therapeutics. Iqbal K., Winblad B., Nishimura T., Takeda M. et Wisniewski H. M. Chichester, John Wiley & Sons, 1997, 239-246.
33. HE Y., DELAÈRE P., DUYCKAERIS C., WASOWICZ M., PIETTE F., HAUW J.-J. Two distinct ubiquitin immunoreactive senile plaques in Alzheimer's disease : relationship with the intellectual status in 29 cases. Acta Neuropathol., 1993, 86 : 109-116.
34. HE Y., DUYCKAERTS C., DELAèRE P., PIETTE F., HAUW J.- J. Alzheimer's lesions labelled by anti-ubiquitin antibodies. Comparison with other staining techniques. Neuropathol. Appl. Neurobiol., 1993, 19 : 364-371.
35. HEMPEN B., BRION J.-P. Reduction of acetylated alphatubulin immunoreactivity in neurofibrillary tanglebearing neurons in Alzheimer's disease. J. Neuropathol Exp. Neurol., 1996, 55 : 964-972.
36. IWATSUBO T., ODAKA A., SUZLKI N., MIZUSAWA H., NUKINA N., IHARA Y. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals : evidence that an initially deposited species is Aβ42 (43). Neuron, 1994. 13 : 45-53.
37. MANN D. M. A., ESIRI M. M. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. J. Neurol. Sci., 1989, 89 : 169-179.
38. MASLIAH E., TERRY R. D. Role of synaptic pathology in the mechanisms of denervation in Alzheimer disease. Clin. Neurosci., 1993, 4 : 192-198.
39. MASTERS C. L., SIMMS G., WEINMAN N. A., MULTHAUP G., MCDONALD B. L., BEYREUTER K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA, 1985, 82 : 4245-4249.
40. OCTAVE J. N. The amyloid peptide and its precursor in Alzheimer's disease. Rev. Neurosci., 1995, 6 : 287-316.
41. PROBST A., ANDERTON B. H., BRION J. P., ULRICH J. Senile plaque neuntes fail to demonstrate antipaired helical filament and anti-microtubule-associated protein tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex. Acta Neuropathol, 1989, 77 : 430-436.
42. REGEUR L., BADSBERG, JENSEN G., PAKKENBERG H., EVANS S. M., PAKKENBERG B. No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type. Neurobiol. Aging, 1994, 15 : 347-352.
43. SCHMIDT M. L., MURRAY J. M., TROJANOWSKI J. Q. Continuity of neuropil threads with tangles-bearing and tangle-free neurons in Alzheimer disease cortex. Mol. Chem. Neuropath., 1993, 18: 299-312.
44. SWAAB D. F., SALEHI A. The pathogenesis of Alzheimer disease : an alternative to the amyloid hypothesis. J. Neuropathol Exp. Neurol., 1997, 56 : 216.
45. TERRY D., MASLIAH E., HANSEN L. A. Structural basis of the cognitive alterations in Alzheimer disease. Alzheimer disease. Terry R. D., Katzman R. et Bick K. L. New York, Raven Press, 1994, 179-196.
46. WIRAK D. O., BAYNEY R., et al. Deposits of amyloid protein in the central nervous system oftransgenic mice. Science, 1991, 253 : 323-325.
47. WISNIEWSKI H. M., TERRY R. D. Reexamination of the pathogenesis ofthe senile plaques. Prog. Neuropathol., 1973, 2: 1-15.