Brain systems mediating aversive conditioning: An event-related fMRI study

Neuron

Volumn 20, Issue 5, 1998, Pages 947-957

  Büchel, Christian ^a   Morris, Jond ^a   Dolan, Raymond J ^a,b   Friston, Karl J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AVERSIVE BEHAVIOR; BRAIN FUNCTION; EMOTION; EVOKED RESPONSE; LEARNING; NERVE POTENTIAL; PRIORITY JOURNAL; STIMULUS RESPONSE;

EID: 0032078081     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80476-6     Document Type: Article

References (58)

1. Alvarez, P., and Squire, L.R. (1994). Memory consolidation and the medial temporal lobe: a simple network model. Proc. Natl. Acad. Sci. USA 91, 7041-7045.
2. Augustine, J.R. (1996). Circuitry and functional-aspects of the insular lobe in primates including humans. Brain Res. Rev. 22, 229-244.
3. Bechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C., and Damasio, A.R. (1995). Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. Science 269, 1115-1118.
4. Bordi, F., and LeDoux, J. (1992). Sensory tuning beyond the sensory system - an initial analysis of auditory response properties of neurons in the lateral amygdaloid nucleus and overlying areas of the striatum. J. Neurosci. 12, 2493-2503.
5. Bordi, F., LeDoux, J., Clugnet, M.C., and Pavlides, C. (1993). Single-unit activity in the lateral nucleus of the amygdala and overlying areas of the striatum in freely behaving rats - rates, discharge patterns, and responses to acoustic stimuli. Behav. Neurosci. 107, 757-769.
6. Breiter, H.C., Etcoff, N.L., Whalen, P.J., Kennedy, W.A., Rauch, S.L., Buckner, R.L., Strauss, M.M., Hyman, S.E., and Rosen, B.R. (1996). Response and habituation of the human amygdala during visual processing of facial expression. Neuron 17, 875-887.
7. Buckner, R.L., Bandettini, P.A., Ocraven, K.M., Savoy, R.L., Petersen, S.E., Raichle, M.E., and Rosen, B.R. (1996). Detection of cortical activation during averaged single trials of a cognitive task using functional magnetic-resonance-imaging. Proc. Natl. Acad. Sci. USA 93, 14878-14883.
8. Cacace, A.T., Margolis, R.H., and Relkin, E.M. (1992). Short-term poststimulatory response characteristics of the human acoustic stapedius reflex - monotic and dichotic stimulation. J. Acoust. Soc. Am. 91, 203-214.
9. Cahill, L., Haier, R.J., Fallon, J., Alkire, M.T., Tang, C., Keator, D., Wu, J., and McGaugh, J.L. (1996). Amygdala activity at encoding correlated with long-term, free-recall of emotional information. Proc. Natl. Acad. Sci. USA 93, 8016-8021.
10. Campeau, S., and Davis, M. (1995). Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned-stimuli. J. Neurosci. 15, 2301-2311.
11. Casey, K.L., Minoshima, S., Morrow, T.J., Koeppe, R.A., and Frey, K.A. (1995). Imaging the brain in pain - potentials, limitations, and implications. Adv. Pain Res. Ther. 22, 201-211.
12. Clark, R.E., and Lavond, D.G. (1993). Reversible lesions of the red nucleus during acquisition and retention of a classically-conditioned behavior in rabbits. Behav. Neurosci. 107, 264-270.
13. Coghill, R.C., Talbot, J.D., Evans, A.C., Meyer, E., Gjedde, A., Bushnell, M.C., and Duncan, G.H. (1994). Distributed-processing of pain and vibration by the human brain. J. Neurosci. 14, 4095-4108.
14. Dale, A.M., and Buckner, R.L. (1997). Selective averaging of rapidly presented individual trials using fMRI. Hum. Brain Map. 5, 329-340.
15. Decety, J., Perani, D., Jeannerod, M., Bettinardi, V., Tadary, B., Woods, R., Mazziotta, J.C., and Fazio, F. (1994). Mapping motor representations with positron emission tomography. Nature 371, 600-602.
16. Desmond, J.E., and Moore, J.W. (1991). Single-unit activity in red nucleus during the classically-conditioned rabbit nictitating-membrane response. Neurosci. Res. 10, 260-279.
17. Devinsky, O., Morrell, M.J., and Vogt, B.A. (1995). Contributions of anterior cingulate cortex to behavior. Brain 118, 279-306.
18. Ekman, P. (1982). Emotion in the Human Face (Cambridge: Cambridge University Press).
19. Esteves, F., Parra, C., Dimberg, U., and Ohman, A. (1994). Nonconscious associative learning - pavlovian conditioning of skin-conductance responses to masked fear-relevant facial stimuli. Psychophysiology 31, 375-385.
20. Evans, A.C., Kamber, M., Collins, D.L., and Macdonald, D. (1994). An MRI-based probabilistic atlas of neuroanatomy. In Magnetic Resonance Scanning and Epilepsy, S. Shorvon, D. Fish, F. Andermann, G. M. Bydder, H. Stefan, eds. (New York: Plenum Press), pp. 263-274.
21. Everitt, B.J., and Robbins, T.W. (1997). Central cholinergic systems and cognition. Annu. Rev. Psych. 48, 649-684.
22. Fanselow, M.S. (1984). What is conditioned fear. Trends Neurosci. 7, 460-462.
23. Fanselow, M.S. (1998). Pavlovian conditioning, negative feedback, and blocking: mechanisms that regulate association formation. Neuron 20, 625-627.
24. Filipek, P.A., Richelme, C., Kennedy, D.N., and Caviness, V.S. (1994). Young-adult human brain - an MRI-based morphometric analysis. Cerebral Cortex 4, 344-360.
25. Fink, G.R., Markowitsch, H.J., Reinkemeier, M., Bruckbauer, T., Kessler, J., and Heiss, W.D. (1996). Cerebral representation of ones own past - neural networks involved in autobiographical memory. J. Neurosci. 16, 4275-4282.
26. Fredrikson, M., Wik, G., Fischer, H., and Andersson, J. (1995). Affective and attentive neural networks in humans - a pet study of pavlovian conditioning. Neuroreport 7, 97-101.
27. Freeman, J.H., Cuppernell, C., Flannery, K., and Gabriel, M. (1996). Limbicthalamic, cingulate cortical and hippocampal neuronal correlates of discriminative approach learning in rabbits. Behav. Brain Res. 80, 123-136.
28. Friston, K.J., Ashburner, J., Frith, C.D., Poline, J.-B., Heather, J.D., and Frackowiak, R.S.J. (1995a). Spatial registration and normalization of images. Hum. Brain Map. 2, 1-25.
29. Friston, K.J., Holmes, A.P., Poline, J.-B., Grasby, P.J., Williams, S. C. R., Frackowiak, R.S.J., and Turner, R. (1995b). Analysis of fMRI time series revisited. NeuroImage 2, 45-53.
30. Friston, K.J., Holmes, A.P., Worsley, K.P., Poline, J.-B., Frith, C.D., and Frackowiak, R.S.J. (1995c). Statistical parametric maps in functional imaging: a general linear approach. Hum. Brain Map. 2, 189-210.
31. Josephs, O., Turner, R., and Friston, K. (1997). Event-related fMRI. Hum. Brain Map. 5, 243-248.
32. Krupa, D.J., Thompson, J.K., and Thompson, R.F. (1993). Localization of a memory trace in the mammalian brain. Science 260, 989-991.
33. Kwong, K.K., Belliveau, J.W., Chesler, D.A., Goldberg, I.E., Weisskoff, R.M., Poncelet, B.P., Kennedy, D.N., Hoppel, B.E., Cohen, M.S., Turner, R., et al. (1992). Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. USA 89, 5675-5679.
34. LaBar, K.S., and LeDoux, J.E. (1996). Partial disruption of fear conditioning in rats with unilateral amygdala damage - correspondence with unilateral temporal lobectomy in humans. Behav. Neurosci. 110, 991-997.
35. LeDoux, J. (1996). A few degrees of separation. In The Emotional Brain. (New York: Simon and Schuster), pp. 138-178.
36. LeDoux, J.E., Cicchetti, P., Xagoraris, A., and Romanski, L.M. (1990a). The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning. J. Neurosci. 10, 1062-1069.
37. LeDoux, J.E., Farb, C.F., and Ruggiero, D.A. (1990b). Topographic organization of neurons in the acoustic thalamus that project to the amygdala. J. Neurosci. 10, 1043-1054.
38. Logan, C.G., and Grafton, S.T. (1995). Functional-anatomy of human eyeblink conditioning determined with regional cerebral glucose-metabolism and positron-emission tomography. Proc. Natl. Acad. Sci. USA 92, 7500-7504.
39. McGaugh, J.L., Cahill, L., and Roozendaal, B. (1996). Involvement of the amygdala in memory storage-interaction with other brain systems. Proc. Natl. Acad. Sci. USA 93, 13508-13514.
40. Mesulam, M.M., and Mufson, E.J. (1982). Insula of the old-world monkey. 3. Efferent cortical output and comments on function. J. Comp. Neurol. 212, 38-52.
41. Miserendino, M.J.D., Sananes, C.B., Melia, K.R., and Davis, M. (1990). Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala. Nature 345, 716-718.
42. Morris, J.S., Friston, K.J., and Dolan, R.J. (1997). Neural responses to salient visual stimuli. Proc. R. Soc. Lond. B. 264, 769-775.
43. Phillips, M.L., Young, A.W., Senior, C., Brammer, M., Andrew, C., Calder, A.J., Bullmore, E.T., Perrett, D.I., Rowland, D., Williams, S.C.R., et al. (1997). A specific neural substrate for perceiving facial expressions of disgust. Nature 389, 495-498.
44. Poremba, A., and Gabriel, M. (1997a). Amygdalar lesions block discriminative avoidance learning and cingulothalamic training-induced neuronal plasticity in rabbits. J. Neurosci. 17, 5237-5244.
45. Poremba, A., and Gabriel, M. (1997b). Medial geniculate lesions block amygdalar and cingulothalamic learning-related neuronal activity. J. Neurosci. 17, 8645-8655.
46. Powell, D.A., Maxwell, B., and Penney, J. (1996). Neuronal-activity in the medial prefrontal cortex during pavlovian eyeblink and nictitating-membrane conditioning. J. Neurosci. 16, 6296-6306.
47. Quirk, G.J., Armony, J.L., and LeDoux, J.E. (1997). Fear conditioning enhances different temporal components of tone-evoked spike trains in auditory cortex and lateral amygdala. Neuron 19, 613-624.
48. Rainville, P., Duncan, G.H., Price, D.D., Carrier, B., and Bushnell, M.C. (1997). Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277, 968-971.
49. Ramnani, N., and Yeo, C.H. (1996). Reversible inactivations of the cerebellum prevent the extinction of conditioned nictitating-membrane responses in rabbits. J. Physiol. 495, 159-168.
50. Rolls, E.T. (1994). A theory of emotion and consciousness, and its application to understanding the neural basis of emotion. In The Cognitive Neurosciences, M.S. Gazzaniga, ed. (Cambridge, MA: MIT Press), pp. 1091-1106.
51. Rolls, E.T., Hornak, J., Wade, D., and McGrath, J. (1994). Emotion-related learning in patients with social and emotional changes associated with frontal-lobe damage. J. Neurol. Neurosurg. Psychiatry 57, 1518-1524.
52. Schreurs, B.G., McIntosh, A.R., Bahro, M., Herscovitch, P., Sunderland, T., and Molchan, S.E. (1997). Lateralization and behavioral correlation of changes in regional cerebral blood flow with classical conditioning of the human eyeblink response. J. Neurophysiol. 77, 2153-2163.
53. Stephan, K.M., Fink, G.R., Passingham, R.E., Silbersweig, D., Ceballosbaumann, A.O., Frith, C.D., and Frackowiak, R.S.J. (1995). Functional-anatomy of the mental representation of upper extremity movements in healthy-subjects. J. Neurophysiol. 73, 373-386.
54. Talairach, P., and Tournoux, J. (1988) A Stereotactic Coplanar Atlas of the Human Brain (Stuttgart: Thieme).
55. Thompson, R.F., and Krupa, D.J. (1994). Organization of memory traces in the mammalian brain. Annu. Rev. Neurosci. 17, 519-549.
56. Whalen, P.J., Rauch, S.L., Etcoff, N.L., McInerney, S.C., Lee, M.B., and Jenike, M.A. (1998). Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. J. Neurosci. 18, 411-418.
57. Worsley, K.J., and Friston, K.J. (1995). Analysis of fMRI time series revisited - again. NeuroImage 2, 173-181.
58. Worsley, K.J., Marrett, P., Neelin, A.C., Friston, K.J., and Evans, A.C. (1996). A unified statistical approach for determining significant signals in images of cerebral activation. Hum. Brain Mapp. 4, 58-73.