Antibacterial agents - Phagocytes: New concepts for old in immunomodulation

International Journal of Antimicrobial Agents

Volumn 10, Issue 1, 1998, Pages 11-21

  Labro, Marie Thérèse ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

Antibacterial agents; Infectious diseases; Phagocytes

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANSAMYCIN DERIVATIVE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; BETA LACTAM ANTIBIOTIC; CEFODIZIME; CHLORAMPHENICOL; CLINDAMYCIN; CLOFAZIMINE; COUMAMYCIN; CYTOKINE; DAPSONE; ETHAMBUTOL; FOSFOMYCIN; GLYCOPEPTIDE; ISONIAZID; LEUKOTRIENE; MACROLIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SULFAMETHOXAZOLE; TRIMETHOPRIM;

DRUG PENETRATION; HUMAN; IMMUNOMODULATION; INFECTION; INFLAMMATORY DISEASE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; REVIEW;

EID: 0032052544     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(98)00012-0     Document Type: Article

References (98)

1. Bergogne-Berezin E Interactions between antibiotics, bacteria and the human immune system: the clinical relevance of in vitro testing. J Chemother. 9(S1):1997;109-115.
2. Labro MT The prohost effect of antimicrobial agents as a predictor of clinical outcome. J Chemother. 9(S1):1997;100-108.
3. Young P White House to expand response to infectious diseases. ASM News. 62:1996;450-451.
4. Vidaver AK Emerging and reemerging infectious diseases. ASM News. 62:1996;583-585.
5. Plotkin SA Vaccination in the 21st century. J Infect Dis. 168:1993;29-37.
6. Friedman H, Klein TW, Yamaguchi H, editors. Microbial infections. Role of biological response modifiers. Advances in experimental medicine and biology. vol. 319. New York: Plenum Press, 1992.
7. Metchnikoff E Nobel Lecture, reprint 1908. Scand J Immunol. 30:1989;383-398.
8. Hellewell PG, Williams TJ, editors. Immunopharmacology of neutrophils. London: Academic Press, 1994.
9. Gordon S, Keshav S, Chung LP Mononuclear phagocytes: tissue distribution and functional heterogeneity. Curr Opin Immunol. 1:1988;26-35.
10. Rappolee DA, Werb Z Secretory products of phagocytes. Curr Opin Immunol. 1:1988;47-55.
11. Medzhitov R, Janeway CA Jr Innate immunity: impact on the adaptive immune response. Curr Opin Immunol. 9:1997;4-9.
12. Fearon DT, Locksley RM The instructive role of innate immunity in the acquired immune response. Science. 272:1996;50-53.
13. Babior BM Oxygen-dependent microbial killing by phagocytes. New Engl J Med. 298:1978;659-668.
14. Lehr HA, Arfors KE Mechanisms of tissue damage by leukocytes. Curr Opin Hematol. 1:1994;92-99.
15. Babior BM Oxidants from phagocytes: agents of defence and destruction. Blood. 64:1984;959-966.
16. Witko-Sarsat V, Descamps-Latscha B Neutrophil-derived oxidants and proteinases as immunomodulatory mediators in inflammation. Mediators Infl. 3:1994;257-273.
17. Smith JA Neutrophils, host defense and inflammation: a double-edged sword. J Leukocyte Biol. 56:1994;672-686.
18. Downey GP, Fukushima T, Fialkow L Signaling mechanisms in human neutrophils. Curr Opin Hematol. 2:1995;76-88.
19. Cohen MS Molecular events in the activation of human neutrophils for microbial killing. Clin Infect Dis. 18(S2):1994;70-79.
20. Kaufmann SHE, Reddehase MJ Infection of phagocytic cells. Curr Opin Immunol. 2:1989;43-49.
21. Clark VL, Bavoil PM., editors. Methods in Enzymology. Vol. 236. Bacterial pathogenesis. Part B: Interaction of pathogenic bacteria with host cells. San Diego: Academic Press, 1996.
22. Faist PD, Meakins J, Schildberg FW. Host defence dysfunction in trauma, shock and sepsis. Mechanism and therapeutic approaches. Berlin, Heidelberg. New York: Springer Verlag, 1993.
23. Feld R The compromised host. Eur J Cancer Clin Oncol. 25(S2):1989;1-7.
24. Repine JE, Beehler CJ Neutrophils and adult respiratory distress syndrome: two interlocking perspectives in 1991. Am Rev Respir Dis. 144:1991;251-252.
25. Labro MT Interaction entre les agents anti- infectieux et les phagocytes. Press Med. 24:1995;992-998.
26. Gemmell CG Antibiotics and neutrophil function- potential immunomodulating activities. J Antimicrob Chemother. 31:1993;23-33.
27. Labro MT Immunomodulatory actions of antibacterial agents. Clin Immunother. 6:1996;454-464.
28. Barrett JF The immunomodulatory activities of antibacterials. Exp Opin Invest Drugs. 4:1995;551-557.
29. Labro MT Immunomodulation by antibacterial agents. Is it clinically relevant? Drugs. 45:1993;319-328.
30. Labro MT Interaction between antimicrobial drugs and phagocytes: an overview. Int J Antimicrob Agents. 3:1993;73-87.
31. Van den Broek PJ Antimicrobial drugs, microorganisms and phagocytes. Rev Infect Dis. 11:1989;213-245.
32. Labro MT Effect of antimicrobial agents on polymorphonuclear neutrophil functions. Raoult D Antimicrobial Agents and Intracellular Pathogens. 1993;87-135 CRC Press, Boca Raton, FL.
33. Labro MT, El Benna J Interaction of antibiotics with the phagocyte oxidative burst. Faist PD, Meakins J, Schildberg FW Host Defence Dysfunction in Trauma, Shock and Sepsis. Mechanism and Therapeutic Approaches. 1993;953-964 Springer Verlag, Berlin.
34. Ritts RE Antibiotics as biological response modifiers. J Antimicrob Chemother. 26:1993;31-36.
35. Neftel KA, Hauser SP, Muller MR Inhibition of granulopoiesis in vivo and in vitro by β-lactam antibiotics. J Infect Dis. 152:1985;90-98.
36. Labro MT Experimental evaluation of antibiotics as immunomodulators. J Chemother. 6(S5):1994;10-14.
37. Shin WS, Min CK, Kim YR, Hoo JH, Kang MW In-vitro effects of cefozidime on leucocyte functions and colony formation from granulocyte-monocyte progenitors. J Antimicrob Chemother. 37:1996;93-103.
38. Pacheco Y, Hosni R, Dagrosa EE, Gormand F et al. Antibiotics and production of granulocyte-macrophage colony stimulating factor by human bronchial epithelial cells in vitro. Arzneim Forsch. 44:1994;559-563.
39. Labro MT, Babin-Chevaye C, Hakim J Effects of cefotaxime and cefodizime on human granulocyte function in vitro. J Antimicrob Chemother. 18:1986;233-237.
40. Labro MT, Amit N, Babin-Chevaye C, Hakim J Cefodizime (HR-221) potentiation of human neutrophil- independant bactericidal activity. J Antimicrob Chemother. 19:1987;331-341.
41. Carlone NA, Cuffini AM, Tullio V, Cavallo G Carbapenems and potential immunomodulating properties. Masihi KN Immunotherapy Infections. 1994;167-176 Marcel Dekker, New York.
42. Matera G, Berlinghieri MC, Foti F, Barreca GS, Foca A Effect of RO 239424, cefotaxime and fleroxacin on functions of human polymorphonuclear cells and cytokine production by human monocytes. J Antimicrob Chemother. 38:1996;799-807.
43. Aoki M, Ono Y, Kunii O, Goldstein E Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leukocytes. J Antimicrob Chemother. 34:1994;383-390.
44. Nielsen JL, Obel N, Storgaard M, Andersen PL Effect of quinolones on the intracellular killing of Staphylococcus aureus in neutrophil granulocytes. J Antimicrob Chemother. 39:1997;617-622.
45. Wenisch C, Parschalk B, Hasenhundl M, Wiesinger E, Graninger W Effect of cefodizime and ceftriaxone on phagocytic function in patients with severe infections. Antimicrob Agents Chemother. 39:1995;672-676.
46. Labro MT, El Benna J, Charlier N, Abdelghaffar H, Hakim J Cefdinir (CI-983), a new oral amino-2-thiazolyl cephalosporin, inhibits human neutrophil myeloperoxidase in the extracellular medium but not the phagolysosome. J Immunol. 152:1994;2447-2455.
47. Kawana M, Kawana C, Yokoo T, Quie PG, Giebink GS Oxidative metabolic products released from polymorphonuclear leucocytes in middle ear fluid during experimental pneumococcal otitis media. Infect Immunol. 59:1991;4084-4088.
48. Kawana M, Kawana C, Giebink GS Penicillin treatment accelerates middle ear inflammation in experimental pneumococcal otitis media. Infect Immunol. 60:1992;1908-1912.
49. Ottonello L, Dallegri F, Dapino P, Pastorino G, Sacchetti C Cytoprotection against neutrophil- delivered oxidant attack by antibiotics. Biochem Pharmacol. 42:1991;2317-2321.
50. Gunther MR, Mao J, Cohen MS Oxidant scavenging activities of ampicillin and sulbactam and their effects on neutrophil function. Antimicrob Agents Chemother. 37:1993;950-956.
51. Labro MT Cefodizime as a biological response modifier: a review of its in-vivo, ex-vivo and in-vitro immunomodulating properties. J Antimicrob Chemother. 26:1990;37-47.
52. Mediterranean Congress. Interactions between antibiotics and immune defense. Proceeding of symposium from the 9th Mediterranean Congress of Chemotherapy, Milan 13-17 June 1994. J Chemother 1994;6(S5);3-31.
53. Mediterranean Congress. Interactions between antibiotics and immune defense. Proceeding of symposium from the 9th Mediterranean Congress of Chemotherapy, Milan 13-17 June 1994. J Chemother 1994;6(S5);3-31.
54. Vanholder R, Dagrosa EE, Van Landschoot N, Waterloos MA, Ringoir SMG Antibiotics and energy delivery to the phagocytosis-associated respiratory burst in chronic hemodialysis patients: a comparison of cefodizime and cotrimoxazole. Nephron. 63:1993;65-72.
55. Meloni F, Ballabio P, Bianchi L, Grassi FA, Gialdroni Grassi G Cefodizime modulates in vitro tumor necrosis factor-alpha, interleukin-6 and interleukin-8 release from human peripheral monocytes. Chemotherapy. 41:1995;289-295.
56. Pascual A Uptake and intracellular activity of antimicrobial agents in phagocytic cells. Rev Med Microbiol. 6:1995;228-235.
57. Silverstein SC, Kabbash C Penetration, retention, intracellular localization and antimicrobial activity of antibiotics within phagocytes. Curr Opin Hematol. 1:1994;85-91.
58. Labro MT Penetration intracellulaire des macrolides. Presse Med. 26(S11):1997;11-15.
59. Labro MT Intraphagocytic uptake of macrolide antibiotics. Bryskier A, Butzler JP, Neu HC, Tulkens PM Macrolides: Chemistry, Pharmacology and Clinical Uses. 1993;379-388 Arnette-Blackwell, Paris.
60. Van den Broek PJ Activity of antibiotics against microorganisms ingested by mononuclear phagocytes. Eur J Clin Microbiol Infect Dis. 10:1991;114-118.
61. Frehel C, Offredo C, de Chastellier C The phagosomal environment protects virulent Mycobacterium avium from killing and destruction by clarithromycin. Infect Immunol. 65:1997;2792-2802.
62. Labro MT Intracellular bioactivity of macrolides. Clin Microbiol Infect. I(S1):1996;24-30.
63. van Rensburg CEJ, Joone G, Anderson R Interactions of the oxygen-dependent antimicrobial system of the human neutrophil with difloxacin, ciprofloxacin, pefloxacin and fleroxacin in the intraphagocytic eradication of Staphylococcus aureus. J Med Microbiol. 32:1990;15-17.
64. Memin E, Panteix G, Revol A Carrier-mediated system for pefloxacin uptake in human monocytes. J Antimicrob Chemother. 40:1997;263-268.
65. Loo KC, Cario AC, Zhang F, Walters JD Regulation of ciprofloxacin uptake in human promyelocytic leukemia cells and polymorphonuclear leukocytes. J Leukocyte Biol. 67:1997;619-623.
66. Vazifeh D, Abdelghaffar H, Labro MT Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin. Antimicrob Agents Chemother. 41:1997;2099-2107.
67. Couvreur P, Fattal E, Andremont A Liposomes and nanoparticles in the treatment of intracellular infections. Pharmaceut Res. 8:1991;1079-1086.
68. Bakker-Woudenberg IAJM Delivery of antimicrobial to infected tissue macrophages. Adv Drug Delivery Rev. 17:1995;5-20.
69. Gomez-Flores R, Tucker SD, Kansal R, Tamez-Guerra R, Mehta RT Enhancement of antibacterial activity of clofazimine against Mycobacterium avium -Mycobacterium intracellulare complex infection induced by IFN-γ is mediated by TNF-α J Antimicrob Chemother. 39:1997;189-197.
70. Bermudez LE, Young LS Activities of amikacin, roxithromycin and azithromycin alone or in combination with tumor necrosis factor against Mycobacterium avium complex. Antimicrob Agents Chemother. 32:1988;1149-1152.
71. Bermudez LE, Inderlied C, Young LS Stimulation with cytokines enhances penetration of azithromycin into human macrophages. Antimicrob Agents Chemother. 35:1991;2625-2629.
72. Labro MT Effects of macrolides on leukocytes and inflammation. Zinner SH, Young LS, Acar JF, Neu HC Expanding indications for the new macrolides, azalides and streptogramins. 1997;101-116 Marcel Dekker, New York.
73. Labro MT, Vazifeh D, Abdelghaffar H. Effect of the new ketolide HMR 3647 on human neutrophil (PMN) function in vitro. In: Program and Abstracts of the 37th Intersci Conf Antimicrob Agents Chemother, 28 September-1 October 1997, Toronto, 1997:Abstract F-256:189.
74. Itkin IH, Menzel ML The use of macrolide antibiotic substances in the treatment of asthma. J Allergy. 45:1970;146-162.
75. Sanchez I Tetracycline treatment in rheumatoid arthritis. Brasil Med. 82:1968;22-31.
76. Mc Conkey B, Situyanake D Effects of rifampicin with and without isoniazid in rheumatoid arthritis. J Rheumatol. 15:1988;46-50.
77. Kobayashi H Airway biofilm disease: its clinical manifestation and therapeutic possibilities of macrolides. J Infect Chemother. 1:1995;1-15.
78. Labro MT. Anti-inflammatory activity of macrolides: a new therapeutic potential? J Antimicrob Chemother 1998:41.
79. Howe RA, Spencer RC Macrolides for the treatment of Pseudomonas aeruginosa infections? J Antimicrob Chemother. 40:1997;153-155.
80. Black PN Anti-inflammatory effects of macrolide antibiotics. Eur Respir J. 10:1997;971-972.
81. Gabler WL, Smith J, Tsukuda N Comparison of doxycycline and a chemically modified tetracycline inhibition of leukocyte functions. Res Immun Chem Pathol Pharmacol. 78:1992;151-180.
82. Abdelghaffar H, Vazifeh D, Labro MT Erythromycin A-derived macrolides modify the functional activities of human neutrophils by altering the phospholipase D phosphatidate phosphohydrolase transduction pathway. J Immunol. 159:1997;3995-4005.
83. Labro MT, Abdelghaffar H, Kirst H. Structure-activity relationships among erythromycylamine derivatives for their effects on human neutrophils in vitro. Program and Abstracts of the 37th Intersci. Conf. Antimicrob. Agents Chemother. 28 September-1 October 1, 1997. Toronto, 1997; Abstract F-268:191.
84. Cox NL, Prowse MV, Maddison MC, Maddison PJ Treatment of early rheumatoid arthritis with rifampicin. Ann Rheum Dis. 51:1992;32-34.
85. Caruso I, Principi N, D'Urbino G, Santandrea S et al. Rifamycin SV administered by intraarticular infiltration shows disease modifying activity in patients with pauci- or polyarticular juvenile rheumatoid arthritis. J Int Med Res. 21:1993;243-256.
86. Van Zyl JM, Basson K, Kriegler A, Van der Walt BJ Mechanisms by which clofazimine and dapsone inhibit the myeloperoxidase system. Biochem Pharmacol. 42:1991;599-608.
87. 2 but not protein kinase C, in the pro-oxidative interactions of clofazimine with human phagocytes. Biochem Pharmacol. 37:1988;4635-4641.
88. 2 by human polymorphonuclear leukocytes in vitro. Antimicrob Agents Chemother. 27:1985;257-262.
89. Ottonello L, Dapino P, Scirocco MC, Balbi A, Bevilacqua M, Dallegri F Sulphonamides as anti- inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation? Clin Sci. 88:1995;331-336.
90. Roberts DE, Curd JG Sulfonamides as anti-inflammatory agents in the treatment of Wegener's granulomatosis. Arthritis Rheum. 33:1990;1590-1593.
91. Laukio A, Sorsa T, Lindy O, Suomalainen K, Saari H, Golub L, Konttinen Y The anticollagenolytic potential of lymecycline in the long-term treatment of reactive arthritis. Arthritis Rheum. 35:1992;195-198.
92. Tilley BC, Alarcon GS, Heyse SP, Trentham DE et al. Minocycline in rheumatoid arthritis. Ann Intern Med. 122:1995;81-89.
93. Shapira L, Soskolne WA, Mouri Y, Barak V, Halabi A, Stabholz A Protection against endotoxic shock and lipopolysaccharide-induced local inflammation by tetracycline: correlation with inhbition of cytokine secretion. Infect Immun. 64:1996;825-828.
94. Ichimura K, Shimazaki Y, Ishibashi T, Higo R Effect of new macrolide roxithromycin upon nasal polyps associated with chronic sinusitis. Auris Nasus Larynx (Tokyo). 23:1996;48-56.
95. Nwariaku FE, Mc Intyre KL, Sikes PJ, Mileski WJ The effect of antimicrobial agents on the induction of tumour necrosis factor by alveolar macrophages in vitro in response to endotoxin. J Antimicrob Chemother. 39:1997;265-267.
96. Frieling JT, Mulder JA, Hendricks T, Curfs JAAJ, Van der Linden CI, Sauerwein RW Differential induction of pro- and anti-inflammatory cytokines in whole blood by bacteria: effects of antibiotic treatment. Antimicrob Agents Chemother. 41:1997;1439-1443.
97. Nan R, Zysk G, Schmidt H, Fischer FR, Stringaris AK, Stuertz K, Bruck W Trovafloxacin delays the antibiotic-induced inflammatory response in experimental pneumococcal meningitis. J Antimicrob Chemother. 39:1997;781-788.
98. Morikawa K, Watabe H, Araake M, Morikawa S Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. Antimicrob Agents Chemother. 40:1996;1366-1370.