The phagosomal environment protects virulent Mycobacterium avium from killing and destruction by clarithromycin

Infection and Immunity

Volumn 65, Issue 7, 1997, Pages 2792-2802

  Fréhel, Claude ^a   Offredo, Catherine ^a   De Chastellier, Chantal ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CLARITHROMYCIN;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; FEMALE; INFECTION RISK; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL;

EID: 1842335098     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.7.2792-2802.1997     Document Type: Article

References (39)

1. Baradelll, L. E., G. L. Plosker, and D. Metavish. 1993. Clarithromycin. A review of its pharmacologic properties and therapeutic use in M. avium intracellulare complex infection in patients with acquired immune deficiency syndrome. Drugs 46:289-312.
2. Barry, C. E., and K. Mdluli. 1996. Drug sensitivity and environmental adaptation of mycobacterial cell wall components. Trends Microbiol. 4:275-281.
3. Béfron, W., C. Alvarez-Dominguez, L. Mayorga, and P. D. Stahl. 1995. Membrane trafficking along the phagocytic pathway. Trends Cell Biol. 5:100-104.
4. Braun, M., A. Waheed, and K. von Figura. 1989. Lysosomal acid phophatase is transported to lysosomes via the cell surface. EMBO J. 8:3633-3640.
5. Carlier, M. B., A. Zenegergh, and P. M. Tulkens, 1987. Cellular uptake and subcellular distribution of roxithromycin and erythromycin in phagocytic cells. J. Antimicrob, Chemother. 20:47-56.
6. Clemens, D. L., and M. A. Horwitz. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J. Exp. Med. 181:257-270.
7. Cohen. Y., C. Perronne, C. Truffot-Pernot, J. Grosset, J. L. Vildé, and J. J. Pocidalo. 1992. Activities of Win-57273, minocycline. clarithromycin, and 14-hydroxy-clarithromycin against Mycobacterium avium complex in human macrophages. Anitmicrob. Agents Chemother. 36:2104-2107.
8. S. de Chastellier, C., C. Fréhel, C, Offredo, and E. Skamene. 1993. Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice. Infect. Immun. 61:3775-3784.
9. de Chastellier, C., T. Lang, and L. Thilo. 1995. Phagocytic processing of the macrophage endoparasite. Mycobacterium avium in comparison to phagosomes which contain Bacillus subtilis or latex beads. Eur. J. Cell Biol. 68:167-182.
10. Doucet-Populaire, F. C. Truffot-Pernot, J. Grosset, and V. Jarlier. 1995. Acquired resistance in Mycobacterium avium complex strains isolated from AIDS patients and beige mice during treatment with clarithromycin. J. Antimicrob. Chemother. 36:129-136.
11. Ellner, J. J., M. J. Goldberger, and D. M. Parenti. 1991. Mycobacterium avium and AIDS: a therapeutic dilemma in rapid evolution. J. Infect. Dis. 163:1326-1335.
12. Fréhel, C., C. de Chastellier, T. Lang, and N. Rastogi. 1986. Evidence for inhibtion of fusion of lysosomal and prelysosomal compartments with phagosomes in macrophages infected with pathogenic Mycobacterium avium. Infect. Immun. 52:252-262.
13. Fréhel, C., C. de Chastellier, C. Offredo, and P. Berche. 1991. Intrarmicrophage growth of Mycobactcrium avium during infection of mice. Infect. Immun. 59:2207-2214.
14. Fréhel, C., A. Ryter, N. Rastogi, and H. David. 1986. The electron transparent zone in phagocytized Mycobacterium avium and other mycobacteria: formation persistence and role in bacterial survival. Ann. Inst. Pasteur/ Microbiol. (Paris) 137b:239-257.
15. Furney, S. K., P. S. Skinner, A. D. Roberts, K. Appelberg, and I. M. Orme. 1992. Capacity of Mycobacterium avium isolates to grow well or poorly in murine macrophages resides in their ability to induce secretion of tumor necrosis factor. Infect. Immun. 60:4410-4413.
16. Gladue, R. P., G. M. Bright, R. E. Isaacson, and M. F. Newborg. 1989. In vitro and in vivo uptake of azithromycin (CP-62. 993) by phagocytic cells: possible mechanism of delivery and release at sites of infection. Antimicrob. Agents Chemother. 33:277-282.
17. Heifets, L., N. Mor, and J. Vanderkolk. 1993. Mycobacterium avium strains resistant to clarithromycin and azithromycin. Antimicrob. Agents Chemother. 37:2364-2370.
18. Heifets, L. B. 1996. Clarithromycin against Mycobacterium complex infections. Tubercle Lung Dis. 77:19-26
19. Horwitz, M. A. 1983, The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
20. Horwitz, M. A., und F. R. Maxfield. 1984. Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J. Cell Biol. 99:1936-1943.
21. Horwitz, M. A., and S. C. Silverstein. 1983. Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocyles is reversibly inhibited by erythromycin and rifampicin. J. Clin. Invest. 71:15-26.
22. Ishiguro, M., H. Koga, S. Kohno, T. Hayashi, K. Yamaguchi, and M. Hirota. 1989. Penetration of macrolides into human polymorphonuclear leucocytes. J. Antimicrobiol. Chemother. 24:719-729.
23. McNeil, M. R., and P. J. Brennan. 1991. Structure, function and biogenesis of the cell envelope of mycobacteria in relation to bacterial physiology, pathogenesis and drug resistance; some thoughts and possibilities arising from recent structural information. Res. Microbiol. 142:451-463.
24. Meyer, A. P., C. Bril-Bazuin, H. Mattic, and P. J. vanden Boek. 1993. Uptake of azithromycin by humam macrophages and enhanced intracellular antibacterial activity against Staphylococcus aureurs. Antimicrob. Agents Chemother. 37:2318-2322.
25. Mor, N., and L. Heifets. 1993. MICs and MBCs of Clarithromycin against Mycobacterium avium within human macrophages. Antimicrob. Agents Chemother. 37:111-114.
26. Mor, N., and L. Heifets. 1993. Inhibition of intracellulur growth of Mycobacteium avium by one pulsed exposure of infected macrophages to clarithromycin. Antimicrob. Agents Chemother. 37:1380-1382.
27. Mor, N., J. Vanderkolk, and L. Heifets. 1994. Accumulation of clarithromyein in macrophages infected with Mycobacterium avium. Pharmacotherapy 14:100-104.
28. Mor, N., J. Vanderkolk, N. Mezo, and L. Heifets. 1994, Effect of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium. Antimicrob. Agents Chemother. 38:2738-2742.
29. Nakagawara, A., and C. F. Nathan. 1983. A simple method for counting adherent cells: application to cultured human monocytes. macrophages and multinucleated giant cells. J. Immunol, Methods 56:261-268.
30. Pedrosa, J., M. Florido, Z. M. Kunzés, A. G. Castro, F. Portaels, J. M. MacFadden, M. T. Silva, and R, Appelberg. 1994. Characterization of the virulence of Mycobacterium avium complex (MAC) isolates in mice, Clin. Exp. Immunol. 98:210-216.
31. Perronne, C., A. Gikas, C. Truffot-Pernot, J. Grosset, J. J. Pocidalo, and J. L. Vilde. 1990. Activities of clarithromycin. sulfisoxazole, and rifabutin against Mycobacterium avium complex multiplication within human macrophages. Antimicroh. Agents Chemother. 34:1508-1511.
32. Perronne, C., A. Gikas, C. Truffot-Pernot, J. Grosset, J. L. Vilde and J. J. Pocidalo. 1991. Activities of spariloxaein, azithromycin, temafloxadn, and rifapentine compared with that of clarilhromycin against multiplication of Mycobacterium avium complex within human macrophages. Antimicrob. Agents Chemother. 35:1356-1359.
33. Prinzis, S., B. Rivoire, and P. J. Hrennan. 1994. Search for the molecular basis of morphological variation in Mycobactiterum avium. Infect. Immun. 62:1946-1951.
34. Rastogi, N., and V. Labrousse. 1991. Extracellular and intracellular activities of clarithromycin used alone or in association with ethambutol and rifampin against Mycobacterium avium complex. Antimicrob. Agents Chemotber, 35:462-470.
35. Skinner, P. S., S. K. Furney, M. K. Jacobs, G. Klapman, J. E. Ellner, and I. Orme. 1994. A bone marrow-derived murine macrophage model for evaluating efficacy of antimicrobial drugs under relevant physiological conditions. Antimicrob. Agents Chemother. 38:2557-2563.
36. Sturgill-Koszycki, S., P. H. Schlesinger, P. Chakrahorty, P. L. Haddix, H. L. Collins, A. K. Fok, R. D. Allen, S. L., Gluck, J. Heuser, and D. G. Russell. 1994. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton ATPase. Science 263:678-681.
37. Truffot-Pernot, C., J. I. Buohong, and J. Grosset. 1991. Effect of pH on the in vitro potency of clarithiromycin against Mycobacterium avium complex. Antimicrob. Agents Chemother. 35:1677-1678.
38. Yajko, D. M., P. S. Nassos, C. A. Sanders, and W. K. Hadley. 1989. Killing by antimycobactcrial agents of AIDS-derived strains of Mycobacterium avium complex inside cells of the mouse macrophage cell line J 774. Am. Rev. Respir. Dis. 140:1198-1203.
39. Yajku, D. M., P. Nassos, C. A. Sanders, P. C. Gonzalez, and W. K. Eladley. 1992. Comparison of the intracellular activities of clarithromycin and erythromycin against Mycobacterium complex strains in J 774 cells and in alveolar macrophages from human immunodeficiency virus type 1-infected individuals. Antimicrob. Agents Chemother. 36:1163-1165.