The effect of quinolones on the intracellular killing of Staphylococcus aureus in neutrophil granulocytes

Journal of Antimicrobial Chemotherapy

Volumn 39, Issue 5, 1997, Pages 617-622

  Nielsen, S L ^a   Obel, N ^a   Storgaard, M ^a   Andersen, P L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DICLOXACILLIN; FLEROXACIN; LOMEFLOXACIN; OFLOXACIN; QUINOLONE DERIVATIVE; SUPEROXIDE;

ARTICLE; BACTERICIDAL ACTIVITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; GRANULOCYTE; HUMAN; HUMAN CELL; INTRACELLULAR KILLING; MINIMUM INHIBITORY CONCENTRATION; NEUTROPHIL; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ADULT; ANTI-INFECTIVE AGENTS; BLOOD BACTERICIDAL ACTIVITY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROQUINOLONES; HUMANS; MICROBIAL SENSITIVITY TESTS; NEUTROPHILS; STAPHYLOCOCCUS AUREUS; SUPEROXIDES;

EID: 0030996560     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/39.5.617     Document Type: Article

References (27)

1. Moulder, J. W. (1985). Comparative biology of intracellular parasitism. Microbiological Reviews 49, 298-337.
2. Tulkens, P. M. (1991). Intracellular distribution and activity of antibiotics. European Journal of Clinical Microbiology & Infectious Diseases 10, 100-6.
3. Yancey, R. J., Sanchez, M. S. & Ford, C. W. (1991). Activity of antibiotics against Staphylococcus aureus with polymorphonuclear neutrophils. European Journal of Clinical Microbiology & Infectious Diseases 10, 107-13.
4. Pocidalo, J.-J. (1989). Use of fluoroquinolones for intracellular pathogens. Reviews of Infectious Diseases 11, Suppl. 5, S979-84.
5. Gemmell, C. G. (1993). Antibiotics and neutrophil function-potential immunomodulating activities. Journal of Antimicrobial Chemotherapy 31, Suppl. B, 23-33.
6. Christiansen, N. O. (1988). A time-course study on Superoxide generation and protein kinase C activation in human neutrophils. FEBS Letters 239, 195-8.
7. Amsterdam, D. (1991). Susceptibility testing of antimicrobials in liquid media. In Antibiotics in Laboratory Medicine, 3rd edn (Lorian, V., Ed.), pp. 53-105. Williams & Wilkins, Baltimore, MD.
8. Nielsen, S. L., Black, F. T., Storgaard, M. & Obel, N. (1995). Evaluation of a method for measurement of intracellular killing of Staphylococcus aureus in human neutrophil granulocytes. APMIS 103, 460-8.
9. Obel, N., Hansen, B., Christensen, M. M., Nielsen, S. L. & Rungby, J. (1993). Methyl mercury, mercuric chloride, and silver lactate decrease Superoxide anion formation and chemotaxis in human polymorphonuclear leucocytes. Human and Experimental Toxicology 12, 361-4.
10. Wolfson, J. S. & Hooper, D. C. (1989). Fluoroquinolone antimicrobial agents. Clinical Microbiology Reviews 2, 378-424.
11. Koga, H. (1987). High-performance liquid chromatography measurement of antimicrobial concentrations in polymorphonuclear leukocytes. Antimicrobial Agents and Chemotherapy 31, 1904-8.
12. Easmon, C. S. F. & Crane, J. P. (1985). Uptake of ciprofloxacin by human neutrophils. Journal of Antimicrobial Chemotherapy 16, 67-73.
13. Pascual, A., Garcia, I. & Perea, E. J. (1989). Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes. Antimicrobial Agents and Chemotherapy 33, 653-6.
14. Pascual, A., Garcia, I. & Perea, E. J. (1990). Uptake and intracellular activity of an optically active ofloxacin isomer in human neutrophils and tissue culture cells. Antimicrobial Agents and Chemotherapy 34, 277-80.
15. Pascual, A., Garcia, I., Conejo, M. C. & Perea, E. J. (1991). Fluorometric and high-performance liquid Chromatographic measurement of quinolone uptake by human neutrophils. European Journal of Clinical Microbiology & Infectious Diseases 10, 969-71.
16. Milatovic, D. (1986). Intraphagocytic activity of ciprofloxacin and Cl 934. European Journal of Clinical Microbiology 5, 659-60.
17. Pemán, J., Cantón, E., Hernández, M. T. & Gobernado, M. (1994). Intraphagocytic killing of Gram-positive bacteria by ciprofloxacin. Journal of Antimicrobial Chemotherapy 34, 965-74.
18. Pascual, A., Martinez-Martinez, L. & Perea, E. J. (1989). Effect of ciprofloxacin and ofloxacin on human polymorphonuclear leukocyte activity against staphylococci. Chemotherapy (Basel) 35, 17-22.
19. Boogaerts, M. A., Malbrain, S., Scheers, W. & Verwilghen, R. L. (1986). Effects of quinolones on granulocyte function in vitro. Infection 14, Suppl. 4, S258-62.
20. van Rensburg, C. E. J., Joone, G. & Anderson, R. (1989). An in vitro investigation of the intraphagocytic bioactivity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin. Chemotherapy (Basel) 35, 273-7.
21. Van der Auwera, P., Prinz, G. & Petrikkos, G. (1991). Activity of intracellular antibiotics. Infection 19, Suppl. 4, S216-23.
22. van den Broek, P. J. (1989). Antimicrobial drugs, microorganisms, and phagocytes. Reviews of Infectious Diseases 11, 213-45.
23. Forsgren, A. & Bergkvist, P.-l. (1985). Effect of ciprofloxacin on phagocytosis. European Journal of Clinical Microbiology 4, 575-8.
24. Aoki, M., Ono, Y., Kunii, O, & Goldstein, E. (1994). Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leucocytes. Journal of Antimicrobial Chemotherapy 34, 383-90.
25. Kubo, S., Matsumoto, T., Takahashi, K., Haraoka, M., Tanaka, M., Sakumoto, M. et al. (1994). Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobials. Chemotherapy (Basel) 40, 333-6.
26. Capecchi, P. L., Blardi, P., De Lalla, A., Ceccatelli, L., Volpi, L., Pasini, F. L. et al. (1995). Pharmacokinetics and pharmacodynamics of neutrophil-associated ciprofloxacin in humans. Clinical Pharmacology and Therapeutics 57, 446-54.
27. van Rensburg, C. E. J., Joone, G. & Anderson, R. (1990). Interactions of the oxygen-dependent antimicrobial system of the human neutrophil with difloxacin, ciprofloxacin, pefloxacin and fleroxacin in the intraphagocytic eradication of Staphylococcus aureus. Journal of Medical Microbiology 32, 15-7.