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1
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0030832480
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Regional cerebral blood flow throughout the sleep-wake cycle
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A PET study showing both corticothalamic deactivation during NREM and selective reactivation of limbic structures above their waking level during REM in the same individuals. Unlike other recent PET studies, this study makes separate comparisons of the REM sleep activation level to both NREM sleep and to waking, thereby providing a more complete view of changes occurring across the behavioral cycle (see also [4]). of outstanding interest
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Braun AR, Balkin TJ, Wesensten NJ, Carson RE, Varga M, Baldwin P, Selbie S, Belenky G, Herscovitch P. Regional cerebral blood flow throughout the sleep-wake cycle. Brain. 120:1997;1173-1197 A PET study showing both corticothalamic deactivation during NREM and selective reactivation of limbic structures above their waking level during REM in the same individuals. Unlike other recent PET studies, this study makes separate comparisons of the REM sleep activation level to both NREM sleep and to waking, thereby providing a more complete view of changes occurring across the behavioral cycle (see also [4]). of outstanding interest.
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(1997)
Brain
, vol.120
, pp. 1173-1197
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Braun, A.R.1
Balkin, T.J.2
Wesensten, N.J.3
Carson, R.E.4
Varga, M.5
Baldwin, P.6
Selbie, S.7
Belenky, G.8
Herscovitch, P.9
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2
-
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0031010834
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Regional cerebral blood flow changes as a function of delta and spindle activity during slow wave sleep in humans
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A PET study showing progressive deactivation of the brainstem reticular formation, thalamus and cortex with deepening NREM sleep as determined by correlating regional cerebral blood flow with delta and spindle EEG activity. It is notable that brainstem reticular formation and limbic cortex, which deactivate with deepening NREM sleep, are then activated to above-waking levels in REM (see also [1,13,14]). of special interest of special interest
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Hofle N, Paus T, Reutens D, Fiset P, Gotman J, Evans AC, Jones BE. Regional cerebral blood flow changes as a function of delta and spindle activity during slow wave sleep in humans. Neurosci. 17:1997;4800-4808 A PET study showing progressive deactivation of the brainstem reticular formation, thalamus and cortex with deepening NREM sleep as determined by correlating regional cerebral blood flow with delta and spindle EEG activity. It is notable that brainstem reticular formation and limbic cortex, which deactivate with deepening NREM sleep, are then activated to above-waking levels in REM (see also [1,13,14]). of special interest of special interest.
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(1997)
Neurosci
, vol.17
, pp. 4800-4808
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Hofle, N.1
Paus, T.2
Reutens, D.3
Fiset, P.4
Gotman, J.5
Evans, A.C.6
Jones, B.E.7
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3
-
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0031003596
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Functional neuroanatomy of human slow wave sleep
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A PET study showing corticothalamic deactivation in NREM including deactivation of those limbic structures which are then activated above their waking levels in REM (see also [13,14]). of special interest of outstanding interest
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Maquet P, Degueldre C, Delfiore G, Aerts J, Peters JM, Luxen A, Franck G. Functional neuroanatomy of human slow wave sleep. J Neurosci. 17:1997;2807-2812 A PET study showing corticothalamic deactivation in NREM including deactivation of those limbic structures which are then activated above their waking levels in REM (see also [13,14]). of special interest of outstanding interest.
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(1997)
J Neurosci
, vol.17
, pp. 2807-2812
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Maquet, P.1
Degueldre, C.2
Delfiore, G.3
Aerts, J.4
Peters, J.M.5
Luxen, A.6
Franck, G.7
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4
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0032472267
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Dissociated pattern of activity in visual cortices and their projections during human rapid eye-movement sleep
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The authors present strong evidence for their theory that during REM sleep, internal information is being processed between extrastriate and limbic cortices while they are functionally isolated from the external world, both in terms of input (from the striate cortex) and output (via the frontal cortex). of outstanding interest
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Braun AR, Balkin TJ, Wesensten NJ, Gwadry F, Carson RE, Varga M, Baldwin P, Belenky G, Herscovitch P. Dissociated pattern of activity in visual cortices and their projections during human rapid eye-movement sleep. Science. 279:1998;91-95 The authors present strong evidence for their theory that during REM sleep, internal information is being processed between extrastriate and limbic cortices while they are functionally isolated from the external world, both in terms of input (from the striate cortex) and output (via the frontal cortex). of outstanding interest.
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(1998)
Science
, vol.279
, pp. 91-95
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Braun, A.R.1
Balkin, T.J.2
Wesensten, N.J.3
Gwadry, F.4
Carson, R.E.5
Varga, M.6
Baldwin, P.7
Belenky, G.8
Herscovitch, P.9
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5
-
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0342460508
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Low frequency (<1 Hz) oscillations in the human sleep electroencephalogram
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The prevalence of the low-frequency oscillations observed by the Steriade group (see [8]) in anesthetized and sleeping cats is recognized for the first time in the human NREM sleep EEG. The findings include a novel 0.7 Hz to 0.8 Hz rhythm as well as a 4 s (0.23Hz) periodicity of spindles and a 21-32s (0.047 Hz) grouping of delta wave activity. of special interest
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Achermann P, Borbely AA. Low frequency (<1 Hz) oscillations in the human sleep electroencephalogram. Neuroscience. 81:1997;213-222 The prevalence of the low-frequency oscillations observed by the Steriade group (see [8]) in anesthetized and sleeping cats is recognized for the first time in the human NREM sleep EEG. The findings include a novel 0.7 Hz to 0.8 Hz rhythm as well as a 4 s (0.23Hz) periodicity of spindles and a 21-32s (0.047 Hz) grouping of delta wave activity. of special interest.
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(1997)
Neuroscience
, vol.81
, pp. 213-222
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Achermann, P.1
Borbely, A.A.2
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6
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0030571584
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Synchronization of low-frequency rhythms in corticothalamic networks
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The slow (<1 Hz) oscillation displays the greatest constancy of rhythm and phase among spatially separated cortical, thalamic reticular and thalamocortical neurons while spindle and delta frequencies show more variability between spatially separated neurons. Thalamically generated spindle 7-14 Hz) and delta (1-4 Hz) oscillations are in fact constrained and grouped by this cortically generated slow (0.3-0.9 Hz) oscillation (which is itself widely transcortically synchronized). These findings emphasize the functional interaction of the neural substrates generating the diverse range of observed oscillatory frequencies. See also [7,20]. of special interest
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Contreras D, Steriade M. Synchronization of low-frequency rhythms in corticothalamic networks. Neuroscience. 76:1997;11-24 The slow (<1 Hz) oscillation displays the greatest constancy of rhythm and phase among spatially separated cortical, thalamic reticular and thalamocortical neurons while spindle and delta frequencies show more variability between spatially separated neurons. Thalamically generated spindle 7-14 Hz) and delta (1-4 Hz) oscillations are in fact constrained and grouped by this cortically generated slow (0.3-0.9 Hz) oscillation (which is itself widely transcortically synchronized). These findings emphasize the functional interaction of the neural substrates generating the diverse range of observed oscillatory frequencies. See also [7,20]. of special interest.
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(1997)
Neuroscience
, vol.76
, pp. 11-24
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Contreras, D.1
Steriade, M.2
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7
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0030045430
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Spindle oscillation in cats: The role of corticothalamic feedback in a thalamically generated rhythm
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See annotation [6]. of special interest
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Contreras D, Steriade M. Spindle oscillation in cats: The role of corticothalamic feedback in a thalamically generated rhythm. J Physiol. 490:1996;159-179 See annotation [6]. of special interest.
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(1996)
J Physiol
, vol.490
, pp. 159-179
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Contreras, D.1
Steriade, M.2
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8
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0030757455
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Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance
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A comprehensive review of recent electrophysiological work by this author's laboratory. of special interest
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Steriade M. Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. Cereb Cortex. 7:1997;583-604 A comprehensive review of recent electrophysiological work by this author's laboratory. of special interest.
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(1997)
Cereb Cortex
, vol.7
, pp. 583-604
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Steriade, M.1
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9
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0031001260
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Consciousness in waking and dreaming: The roles of neuronal oscillation and neuromodulation in determining similarities and differences
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An integration of recent findings in cellular neurophysiology, electrophysiology of gamma oscillations and the phenomenology of dreaming. of special interest
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Kahn D, Pace-Schott EF, Hobson JA. Consciousness in waking and dreaming: The roles of neuronal oscillation and neuromodulation in determining similarities and differences. Neuroscience. 78:1996;13-38 An integration of recent findings in cellular neurophysiology, electrophysiology of gamma oscillations and the phenomenology of dreaming. of special interest.
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(1996)
Neuroscience
, vol.78
, pp. 13-38
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Kahn, D.1
Pace-Schott, E.F.2
Hobson, J.A.3
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10
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0031014218
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High-frequency gamma-electroencephalogram activity in association with sleep-wake states in the rat
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One of the first studies demonstrating the state-dependent occurrence of gamma frequency oscillation in the rat. Gamma frequency oscillations were associated with aroused states of active waking and REM sleep and it was found that it was gamma, and not beta, activity which varies reciprocally with delta activity. of special interest
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Maloney KJ, Cape EG, Gotman J, Jones BE. High-frequency gamma-electroencephalogram activity in association with sleep-wake states in the rat. Neuroscience. 76:1997;541-555 One of the first studies demonstrating the state-dependent occurrence of gamma frequency oscillation in the rat. Gamma frequency oscillations were associated with aroused states of active waking and REM sleep and it was found that it was gamma, and not beta, activity which varies reciprocally with delta activity. of special interest.
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(1997)
Neuroscience
, vol.76
, pp. 541-555
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Maloney, K.J.1
Cape, E.G.2
Gotman, J.3
Jones, B.E.4
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11
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0029867342
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Intracortical and corticothalamic coherency of fast spontaneous oscillations
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See annotations [27]. of special interest
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Steriade M, Amzica F. Intracortical and corticothalamic coherency of fast spontaneous oscillations. Proc Natl Acad Sci USA. 93:1996;2533-2538 See annotations [27]. of special interest.
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(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2533-2538
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Steriade, M.1
Amzica, F.2
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12
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0030100535
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Variations in sleep mentation as a function of time of night
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The length and content of mentation reports collected from sleep-onset, stage 2 NREM sleep, and REM sleep were compared. REM reports were significantly longer than both NREM and sleep-onset reports, and were both more bizarre and more vivid. The persistence of this difference even when REM reports were corrected for their greater length constitutes firm evidence of a qualitative psychological difference between REM and NREM mentation. of special interest
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Casagrande M, Violani C, Lucidi F, Buttinelli E, Berlini M. Variations in sleep mentation as a function of time of night. Int J Neurosci. 85:1996;19-30 The length and content of mentation reports collected from sleep-onset, stage 2 NREM sleep, and REM sleep were compared. REM reports were significantly longer than both NREM and sleep-onset reports, and were both more bizarre and more vivid. The persistence of this difference even when REM reports were corrected for their greater length constitutes firm evidence of a qualitative psychological difference between REM and NREM mentation. of special interest.
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(1996)
Int J Neurosci
, vol.85
, pp. 19-30
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Casagrande, M.1
Violani, C.2
Lucidi, F.3
Buttinelli, E.4
Berlini, M.5
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13
-
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0029828471
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Functional neuroanatomy of human rapid-eye-movement sleep and dreaming
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A PET study showing REM sleep-related activation of limbic structures and deactivation of association cortex relative to other behavioral states. of special interest
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Maquet P, Peters JM, Aerts J, Delfiore G, Degueldre C, Luxen A, Franck G. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature. 383:1996;163 A PET study showing REM sleep-related activation of limbic structures and deactivation of association cortex relative to other behavioral states. of special interest.
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(1996)
Nature
, vol.383
, pp. 163
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Maquet, P.1
Peters, J.M.2
Aerts, J.3
Delfiore, G.4
Degueldre, C.5
Luxen, A.6
Franck, G.7
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14
-
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0030770943
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Forebrain activation in REM sleep: An FDG PET study
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A PET study showing REM sleep-related activation of subcortical and cortical limbic structures relative to waking. of special interest
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Nofzinger EA, Mintun MA, Wiseman MB, Kupfer DJ, Moore RY. Forebrain activation in REM sleep: An FDG PET study. Brain Res. 770:1997;192-201 A PET study showing REM sleep-related activation of subcortical and cortical limbic structures relative to waking. of special interest.
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(1997)
Brain Res
, vol.770
, pp. 192-201
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Nofzinger, E.A.1
Mintun, M.A.2
Wiseman, M.B.3
Kupfer, D.J.4
Moore, R.Y.5
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15
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0002892680
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Consciousness as a state-dependent phenomenon
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J. Cohen, Schooler J. Mahwah, New Jersey: Lawrence Erlbaum
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Hobson JA. Consciousness as a state-dependent phenomenon. Cohen J, Schooler J. Scientific Approaches to the Question of Consciousness. 1997;379-396 Lawrence Erlbaum, Mahwah, New Jersey.
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(1997)
Scientific Approaches to the Question of Consciousness
, pp. 379-396
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Hobson, J.A.1
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16
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0030958945
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Dreaming as delirium: A mental status exam of our nightly madness
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Hobson JA. Dreaming as delirium: a mental status exam of our nightly madness. Semin Neurol. 17:1997;121-128.
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(1997)
Semin Neurol
, vol.17
, pp. 121-128
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Hobson, J.A.1
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17
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0031081075
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Changes in cerebral blood flow velocity in healthy young men during overnight sleep and while awake
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Kuboyama T, Hori A, Sato T, Nikami T, Yamaki T, Veda S. Changes in cerebral blood flow velocity in healthy young men during overnight sleep and while awake. Electroencephalogr Clin Neurophysiol. 102:1997;125-131.
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(1997)
Electroencephalogr Clin Neurophysiol
, vol.102
, pp. 125-131
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Kuboyama, T.1
Hori, A.2
Sato, T.3
Nikami, T.4
Yamaki, T.5
Veda, S.6
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18
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0029892036
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Arousal: Revisiting the reticular activating system
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Steriade M. Arousal: revisiting the reticular activating system. Science. 272:1996;225-226.
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(1996)
Science
, vol.272
, pp. 225-226
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Steriade, M.1
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19
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0030598401
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Coupled slow and delta oscillations between cuneothalamic and thalamocortical neurons in the chloralose anaesthetized cat
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These authors replicate Steriade's findings (see [8]) of functional interactions between the neural substrates generating diverse oscillatory frequencies. of special interest
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Marino J, Martinez L, Canedo A. Coupled slow and delta oscillations between cuneothalamic and thalamocortical neurons in the chloralose anaesthetized cat. Neurosci Lett. 219:1996;107-110 These authors replicate Steriade's findings (see [8]) of functional interactions between the neural substrates generating diverse oscillatory frequencies. of special interest.
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(1996)
Neurosci Lett
, vol.219
, pp. 107-110
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Marino, J.1
Martinez, L.2
Canedo, A.3
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20
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0343765773
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Cellular substrates and laminar profile of sleep K-complex
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K-complexes occur with a periodicity of 0.5-0.9 Hz and the occurrence of K-complexes becomes synchronized transcortically as well as in the thalamus. This rhythmicity may reflect the influence of cortically generated slow (<1 Hz) oscillations and the K-complex may contribute to the synchronization of fast gamma frequency oscillations. See also annotation [6]. of special interest
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Amzica F, Steriade M. Cellular substrates and laminar profile of sleep K-complex. Neuroscience. 82:1998;671-686 K-complexes occur with a periodicity of 0.5-0.9 Hz and the occurrence of K-complexes becomes synchronized transcortically as well as in the thalamus. This rhythmicity may reflect the influence of cortically generated slow (<1 Hz) oscillations and the K-complex may contribute to the synchronization of fast gamma frequency oscillations. See also annotation [6]. of special interest.
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(1998)
Neuroscience
, vol.82
, pp. 671-686
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Amzica, F.1
Steriade, M.2
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21
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0030461640
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Low-frequency rhythms in the thalamus of intact-cortex and decorticated cats
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Further evidence supporting these authors' suggestion (see [8]) that the slow (<1 Hz) oscillation is of cortical origin. Additionally, they show cortical modification of thalamically generated spindle frequency oscillation. of special interest
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Timofeev I, Steriade M. Low-frequency rhythms in the thalamus of intact-cortex and decorticated cats. J Neurophysiol. 76:1996;4152-4168 Further evidence supporting these authors' suggestion (see [8]) that the slow (<1 Hz) oscillation is of cortical origin. Additionally, they show cortical modification of thalamically generated spindle frequency oscillation. of special interest.
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(1996)
J Neurophysiol
, vol.76
, pp. 4152-4168
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Timofeev, I.1
Steriade, M.2
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22
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0030862893
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Cellular-synaptic generation of sleep spindles, spike-and-wave discharges, and evoked thalamocortical responses in the neocortex of the rat
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Kandel A, Buzsaki G. Cellular-synaptic generation of sleep spindles, spike-and-wave discharges, and evoked thalamocortical responses in the neocortex of the rat. J Neurosci. 17:1997;6783-6797.
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(1997)
J Neurosci
, vol.17
, pp. 6783-6797
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Kandel, A.1
Buzsaki, G.2
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23
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0031060037
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Human cortical oscillations: A neuromagnetic view through the skull
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Hari R, Salmelin R. Human cortical oscillations: a neuromagnetic view through the skull. Trends Neurosci. 20:1997;44-49.
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(1997)
Trends Neurosci
, vol.20
, pp. 44-49
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Hari, R.1
Salmelin, R.2
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24
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0029922346
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Progressive cortical synchronization of ponto-geniculo-occipital potentials during rapid eye movement in sleep
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In extracellular recordings from the cat, ponto-geniculo-occipital (PGO) waves appear synchronously at multiple cortical sites and become increasingly synchronized over the course of a REM period. This transcortical synchrony of PGO wave arrival may underlie the progressive synchronization of gamma-frequency fast oscillations that follow PGO wave arrival at widespread cortical sites during REM. This report highlights the important finding that endogenous REM-related stimuli are effective in evoking the same synchronization of gamma oscillation as exogenous sensory stimuli. of special interest
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Amzica F, Steriade M. Progressive cortical synchronization of ponto-geniculo-occipital potentials during rapid eye movement in sleep. Neuroscience. 2:1996;309-314 In extracellular recordings from the cat, ponto-geniculo-occipital (PGO) waves appear synchronously at multiple cortical sites and become increasingly synchronized over the course of a REM period. This transcortical synchrony of PGO wave arrival may underlie the progressive synchronization of gamma-frequency fast oscillations that follow PGO wave arrival at widespread cortical sites during REM. This report highlights the important finding that endogenous REM-related stimuli are effective in evoking the same synchronization of gamma oscillation as exogenous sensory stimuli. of special interest.
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(1996)
Neuroscience
, vol.2
, pp. 309-314
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Amzica, F.1
Steriade, M.2
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25
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0029742202
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Chattering cells: Superficial pyramidal neurons contributing to the generation of synchronous oscillations in the visual system
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Intracellular recordings in anesthetized cats identified a specific class of superficial pyramidal neurons in the striate and prestriate cortex (termed 'chattering cells') which characteristically generate intrinsic gamma-frequency bursts in response to direct electrical as well as visual stimulation. Notably, the authors describe a specific neuronal type with intrinsic firing in the gamma range which may be important in the initiation, spread and synchronization of stimulus-linked gamma frequency oscillations in the cortex. of special interest
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Gray CM, McCormick DA. Chattering cells: superficial pyramidal neurons contributing to the generation of synchronous oscillations in the visual system. Science. 274:1996;109-113 Intracellular recordings in anesthetized cats identified a specific class of superficial pyramidal neurons in the striate and prestriate cortex (termed 'chattering cells') which characteristically generate intrinsic gamma-frequency bursts in response to direct electrical as well as visual stimulation. Notably, the authors describe a specific neuronal type with intrinsic firing in the gamma range which may be important in the initiation, spread and synchronization of stimulus-linked gamma frequency oscillations in the cortex. of special interest.
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(1996)
Science
, vol.274
, pp. 109-113
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Gray, C.M.1
McCormick, D.A.2
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26
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0029670290
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Role of reticular activation in the modulation of intracortical synchronization
-
The mesencephalic reticular formation of the cat was electrically activated resulting in an enhanced stimulus-induced synchronization in the visual cortex and a shift in EEG frequency components from low to the gamma frequency range. The authors concluded that an activated brain exhibits gamma range frequencies and enhances stimulus - response synchronization. This is an important replication of Steriade's observation (see [8]) taht arousal-related desynchronization versus synchronization is dependent upon the frequency range being observed. See also [18,27]. of special interest
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Munk MHJ, Roelfsema PR, Konig P, Engel AK, Singer W. Role of reticular activation in the modulation of intracortical synchronization. Science. 272:1996;271-274 The mesencephalic reticular formation of the cat was electrically activated resulting in an enhanced stimulus-induced synchronization in the visual cortex and a shift in EEG frequency components from low to the gamma frequency range. The authors concluded that an activated brain exhibits gamma range frequencies and enhances stimulus - response synchronization. This is an important replication of Steriade's observation (see [8]) taht arousal-related desynchronization versus synchronization is dependent upon the frequency range being observed. See also [18,27]. of special interest.
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(1996)
Science
, vol.272
, pp. 271-274
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-
Munk, M.H.J.1
Roelfsema, P.R.2
Konig, P.3
Engel, A.K.4
Singer, W.5
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27
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0030052626
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Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation
-
Recording both intra- and extracellularly in the cortex of cats, the authors find that an activated brain either while awake or in the REM state, results in an increase in the cortical synchronization, amplitude and occurrence of gamma-range oscillations. Their data predicts that these high-frequency cortical neurons would become synchronized by a relevant external stimulus while awake or by an internal stimulus when in REM. of special interest
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Steriade M, Amzica F, Contreras D. Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation. J Neurosci. 16:1996;392-417 Recording both intra- and extracellularly in the cortex of cats, the authors find that an activated brain either while awake or in the REM state, results in an increase in the cortical synchronization, amplitude and occurrence of gamma-range oscillations. Their data predicts that these high-frequency cortical neurons would become synchronized by a relevant external stimulus while awake or by an internal stimulus when in REM. of special interest.
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(1996)
J Neurosci
, vol.16
, pp. 392-417
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Steriade, M.1
Amzica, F.2
Contreras, D.3
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28
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0029991879
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Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks
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See annotation [27]. of special interest
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Steriade M, Contreras D, Amzica F, Timofeev I. Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks. J Neurosci. 16:1996;2788-2808 See annotation [27]. of special interest.
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(1996)
J Neurosci
, vol.16
, pp. 2788-2808
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Steriade, M.1
Contreras, D.2
Amzica, F.3
Timofeev, I.4
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30
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0342902629
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Unit activity of rat basal forebrain neurons - Relationship to cortical activity
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Nunez A. Unit activity of rat basal forebrain neurons - relationship to cortical activity. Neuroscience. 72:1996;757-766.
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(1996)
Neuroscience
, vol.72
, pp. 757-766
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Nunez, A.1
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31
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0030908282
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Positron emission tomography studies of sleep and sleep disorders
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A recent review on PET studies of sleep. of special interest
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Maquet P. Positron emission tomography studies of sleep and sleep disorders. J Neurol. 244:1997;S23-S28 A recent review on PET studies of sleep. of special interest.
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(1997)
J Neurol
, vol.244
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Maquet, P.1
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32
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0031009821
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REM sleep and the amygdala
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An interesting discussion on the functional significance of this group's PET findings. of special interest
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Maquet P, Franck G. REM sleep and the amygdala. Mol Psychiatry. 2:1997;195-196 An interesting discussion on the functional significance of this group's PET findings. of special interest.
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(1997)
Mol Psychiatry
, vol.2
, pp. 195-196
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Maquet, P.1
Franck, G.2
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33
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0029890626
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Sleep states, memory processes and synaptic plasticity
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Smith C. Sleep states, memory processes and synaptic plasticity. Behav Brain Res. 78:1996;49-56.
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(1996)
Behav Brain Res
, vol.78
, pp. 49-56
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Smith, C.1
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