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Volumn 274, Issue 5284, 1996, Pages 109-113

Chattering cells: Superficial pyramidal neurons contributing to the generation of synchronous oscillations in the visual cortex

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOPHYSICS; CAT; DEPOLARIZATION; INTRACELLULAR RECORDING; MEMBRANE POTENTIAL; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; STRIATE CORTEX; VISUAL CORTEX; VISUAL STIMULATION;

EID: 0029742202     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5284.109     Document Type: Article
Times cited : (693)

References (54)
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    • We selected a sample of 28 visually responsive cells that we recorded long enough to collect at least 20 responses to the presentation of an optimally oriented drifting light bar. The spike trains were extracted from each trial and quantified with the use of two measures: the mean firing rate across trials for a 500-ms epoch centered on the peak of the visual response and the percentage of interspike intervals occurring during the visual responses that were <3 ms in duration. For the subthreshold membrane potential, we visually selected two 512-ms epochs from each trial, one during the period of spontaneous activity and the other centered on the peak of the visual response. For both epochs on each trial, we applied a seven-point median filter to remove the action potentials and stored the resulting signals at a resolution of 1 ms. The data were digitally filtered (10 to 100 Hz) to remove both low- and high-frequency components. The power spectrum was then computed for each epoch of data. The sum of all values in each spectrum between 25 and 65 Hz was computed and the distributions were compared, after normalization to the largest value in the data set, with the use of the Kolmogorov-Smirnov test.
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    • We thank L. Nowak and R. Azouz for their valuable contributions to this work. Supported by a grant from the National Eye Institute and a contract from the Office of Naval Research to C.M.G., and by grants from NIH and NSF to D.M.


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