TIF1α: A possible link between KRAB zinc finger proteins and nuclear receptors

Journal of Steroid Biochemistry and Molecular Biology

Volumn 65, Issue 1-6, 1998, Pages 43-50

  Le Douarin, B ^a   You, J ^a   Nielsen, A L ^a   Chambon, P ^a   Losson, R ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION INTERMEDIARY FACTOR 1ALPHA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CELL RECEPTOR; HETEROCHROMATIN SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP 1; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; NONHISTONE PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTIONAL INTERMEDIARY FACTOR 1; TRIM28 PROTEIN, MOUSE; ZNF10 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CHROMATIN STRUCTURE; CONFERENCE PAPER; HELA CELL; HETEROCHROMATIN; HUMAN; HUMAN CELL; MONKEY; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; ANIMAL; ARTICLE; CHROMATIN; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; METABOLISM; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ANIMALS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MICE; NUCLEAR PROTEINS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

EID: 0032034251     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(97)00175-1     Document Type: Conference Paper

References (35)

1. Mangelsdorf D. J., Thummel C., Beato M., Herrlich P., Schütz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., Evans R. M. The nuclear receptor superfamily: The second decade. Cell. 83:1995;835-839.
2. Beato M., Sanchez-Pacheco A. Interaction of steroid hormone receptors with the transcription initiation complex. Endocrine Reviews. 17:1996;587-609.
3. Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J. 10:1996;940-954.
4. Bourguet W., Ruff M., Chambon P., Gronemeyer H. G., Moras D. Crystal structure of the ligand binding domain of the human nuclear receptor RXRα Nature. 375:1995;377-382.
5. Renaud J. P., Rochel N., Ruff M., Vivat V., Chambon P., Gronemeyer H., Moras D. Crystal structure of the RARγ ligand-binding domain bound to all-trans retinoic acid. Nature. 378:1995;681-689.
6. Wagner R. L., Apriletti J. W., McGrath M. E., West B. L., Baxter J. D., Fletterick R. J. A structural role for hormone in the thyroid hormone receptor. Nature. 378:1995;690-697.
7. Wurtz J. M., Bourguet W., Renaud J. P., Vivat V., Chambon P., Moras D., Gronemeyer H. A canonical structure for the ligand binding domain of nuclear receptors. Nature Struct. Biol. 3:1996;87-94.
8. Katzellenbogen J. A., Katzellenbogen B. S. Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses. Chem. Biol. 3:1996;529-536.
9. Glass C. K., Rose D. W., Rosenfeld M. G. Nuclear receptor coactivators. Curr. Opin. Biol. 9:1997;222-232.
10. Meyer M. E., Gronemeyer H., Turcotte B., Bocquel M. T., Tasset D., Chambon P. Steroid hormone receptors compete for factors that mediate their enhancer function. Cell. 57:1989;433-442.
11. Horwitz K. B., Jackson T. A., Bain D. L., Richer J. K., Takimoto G. S., Tung L. Nuclear receptor coactivators and corepressors. Mol. Endocrinol. 10:1996;1167-1177.
12. Le Douarin B., Zechel C., Garnier J.-M., Lutz Y., Tora L., Pierrat B., Heery D., Gronemeyer H., Chambon P., Losson R. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 14:1995;2020-2033.
13. Aasland R., Gibson T. J., Stewart A. F. The PHD finger: Implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci. 20:1995;56-59.
14. Jeanmougin F., Wurtz J. M., Le Douarin B., Chambon P., Losson R. The bromodomain revisited. TIBS. 22:1997;151-153.
15. Le Douarin B., Lade Nielsen A., Garnier J.-M., Ichinose H., Jeanmougin F., Losson R., Chambon P. A possible involvement of TIF1α and TIF1β in the epigenetic control of transcription by nuclear receptors. EMBO J. 15:1996;6701-6715.
16. Kim S.-S., Chen Y.-M., O'Leary E., Witzgall R., Vidal M., Bonventre J. V. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc. Natl. Acad. Sci. USA. 93:1996;15299-15304.
17. Moosmann P., Georgiev O., Le Douarin B., Bourquin J. P., Schaffner W. Transcriptional repression by RING finger protein TIF1β that interacts with the KRAB repression domain of KOX1. Nucleic Acids Res. 24:1996;4859-4867.
18. Friedman J. R., Fredericks W. J., Jensen D. E., Speicher D. W., Huang X.-P., Neilson E. G., Rauscher F. J. III KAP-1, a novel corepressor for the highly conserved KRAB repression domain. Genes Dev. 10:1996;2067-2078.
19. Fields S., Sternglanz R. The two-hybrid system: An assay for protein-protein interactions. Trends Genet. 10:1994;286-292.
20. Le Douarin B., Pierrat B., vom Baur E., Chambon P., Losson R. A new version of the two-hybrid assay for detection of protein-protein interactions. Nucleic Acids Res. 23:1995;876-878.
21. Cavaillès V., Dauvois S., L'Horset F., Lopez G., Hoare S., Kushner P. J., Parker M. G. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J. 14:1995;3741-3751.
22. Lee J. W., Choi H.-S., Gyurist J., Brent R., Moore D. D. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol. 9:1995;243-254.
23. vom Baur E., Zechel C., Heery D., Heine M., Garnier J. M., Vivat V., Le Douarin B., Gronemeyer H., Chambon P., Losson R. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J. 15:1996;110-124.
24. Nicol L., Jeppesen P. Human autoimmune sera recognize a conserved 26 kDa protein associated with mammalian heterochromatin that is homologous to heterochromatin protein 1 of Drosophila. Chromosome Res. 2:1994;245-253.
25. Wreggett K. A., Hill F., James P. S., Hutchings A., Butcher G. W., Singh P. B. A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin. Cytogenet. Cell Genet. 66:1994;99-103.
26. Elgin S. R. C. Heterochromatin and gene regulation in Drosophila. Curr. Opin. Genet. Dev. 6:1996;193-202.
27. Koonin E. V., Zhou S., Lucchesi J. C. The chromo superfamily: New members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res. 23:1995;4229-4233.
28. Aasland R., Stewart A. F. The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucleic Acids Res. 23:1995;3163-3173.
29. Platero J. S., Hartnett T., Eissenberg J. C. Functional analysis of the chromo domain of HP1. EMBO J. 14:1995;3977-3986.
30. Chiba H., Muramatsu M., Nomoto A., Kato H. Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res. 22:1994;1815-1820.
31. Wang W., Côté J., Xue Y., Zhou S., Kuo A., Cairns B. R., Crabtree G. R. Diversity and specialization of mammalian SWI/SNF complexes. Genes and Dev. 10:1996;2117-2130.
32. Margolin J. F., Friedman J. R., Meyer W. K.-H., Vissing H., Thiesen H.-J., Rauscher F. J. III Krüppel-associated boxes are potent transcriptional repression domains. Proc. Natl. Acad. Sci. USA. 91:1994;4509-4513.
33. Witzgall R., O'Leary E., Leaf A., Önaldi D., Bonventre J. V. The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. Proc. Natl. Acad. Sci. USA. 91:1994;4514-4518.
34. Bellefroid E. J., Poncelet D. A., Lecocq P. J., Revelant O., Martial J. A. The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. Proc. Natl. Acad. Sci. USA. 88:1991;3608-3612.
35. Deuschle U., Meyer W. K.-H., Thiesen H.-J. Tetracycline-reversible silencing of eukaryotic promoters. Mol. Cell. Biol. 15:1995;1907-1914.