Probing of conformational changes in human O6-alkylguanine-DNA alkyl transferase protein in its alkylated and DNA-bound states by limited proteolysis

Biochemical Journal

Volumn 329, Issue 3, 1998, Pages 545-550

  Kanugula, Sreenivas ^a   Goodtzova, Karina ^a   Pegg, Anthony E ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; DNA; DOUBLE STRANDED DNA; MUTANT PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYPEPTIDE; PROTEINASE; SINGLE STRANDED DNA; TRYPSIN;

ALKYLATION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPAIR; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0032007591     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3290545     Document Type: Article

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