Development of murine allergic asthma is dependent upon B7-2 costimulation

Journal of Immunology

Volumn 160, Issue 2, 1998, Pages 1036-1043

  Keane Myers, Andrea M ^a   Gause, William C ^c   Finkelman, Fred D ^b   Xhou, X D ^c   Wills Karp, Marsha ^a,d  

^a Johns Hopkins University   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; B7 ANTIGEN; CD28 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; DATA ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNE RESPONSE; LOEFFLER PNEUMONIA; LUNG LAVAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE DIAGNOSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD86; ASTHMA; BRONCHIAL HYPERREACTIVITY; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; LUNG; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED A; TH2 CELLS;

EID: 0031975063     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. Bentley, C. Corrigan, S. Durham, and B. Kay. 1992. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298.
2. Walker, C., E. Bode, L. Boer, T. Hansel, K. Blaser, and J. Johann-Christian Virchow. 1992. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146:109.
3. Del Prete, G. F., M. De Carli, M. M. D'Elios, P. Maestrelli, M. Ricci, L. Fabbri, and S. Romagnini. 1993. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur. J. Immunol. 23:1445.
4. Wang, J. M., A. Rambaldi, A. Biondi, Z. G. Chen, C. J. Sanderson, and A. Montovani. 1989. Recombinant human interleukin-5 is a selective eosinophil chemoattractant. Eur. J. Immunol. 19:701.
5. Lopez, A. F., C. J. Sanderson, J. R. Gamble, H. R. Campbell, I. G. Young, and M. A. Vadas. 1988. Recombinant human interleukin-5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219.
6. Yamaguchi, Y., T. Suda, S. Ohta, K. Tominaga, Y. Miura, and T. Kasahara. 1991. Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature eosinophils. Blood 78:2542.
7. Finkelman, F. D., I. M. Katona, J. F. Urban, Jr., J. Holmes, J. Ohara, A. S. Tung, J. G. Sample, and W. E. Paul. 1988. Interleukin-4 is required to generate and sustain in vivo IgE responses. J. Immunol. 141:2335.
8. + T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10:587.
9. Gavett, S. H., D. J. O'Hearn, X. Li, S.-K. Huang, F. D. Finkelman, and M. Wills-Karp. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
10. Schwartz, R. H. 1992. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71:1065.
11. Harding, F. A., J. G. McArthur, J. A. Gross, D. H. Raulet, and J. P. Allison. 1992. CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356:607.
12. Bluestone, J. A. 1995. New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2:555.
13. June, C. H., J. A. Bluestone, L. M. Nadler, and C. B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today 15:321.
14. Wallace, P. M., J. S. Johnson, J. F. MacMaster, K. A. Kennedy, P. Gladstone, and P. S. Linsley. 1994. CTLA-4Ig treatment ameliorates the lethality of murine graft-versus host disease across major histocompatibility complex barriers. Transplantation 58:602.
15. Tan, P., C. Anasetti, J. A. Hansen, J. Melrose, M. Brunvard, K. Bradshaw, J. A. Ledbetter, and P. S. Linsley. 1993. Induction of alloantigen-specific unresponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J. Exp. Med. 177:165.
16. Boussiotis, V. A., G. J. Freeman, G. Gray, J. G. Gribben, and L. M. Nadler. 1993. B7 but not intracellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J. Exp. Med. 178:1753.
17. Linsley, P. S., P. M. Wallace, J. Johnson, M. G. Gibson, J. L. Greene, J. A. Ledbetter, C. Singh, and M. A. Tepper. 1992. Immunosuppression in vivo by a soluble form of the CTLA4 T cell activation molecule. Science 257:792.
18. Lenschow, D. J., Y. Zeng, J. R. Thistlethwaite, A. Montag, W. Brady, M. G. Gibson, P. S. Linsley, and J. A. Bluestone. 1992. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA-4Ig. Science 257:789.
19. Finck, B. K., P. S. Linsley, and D. Wofsy. 1994. Treatment of murine lupus with CTLA-4Ig. Science 265:1225.
20. Lu, P., X. Di Zhou, S. J. Chen, M. Moorman, S. C. Morris, F. D. Finkelman, P. Linsley, J. F. Urban, and W. C. Gause. 1994. CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite. J. Exp. Med. 180:693.
21. Corry, D. B., S. L. Reiner, P. S. Linsley, and R. M. Locksley. 1994. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J. Immunol. 153:4142.
22. Lu, P., X. Di Zhou, S. Chen, M. Moorman, A. Schoneveld, S. Morris, F. D. Finkelman, P. Linsley, E. Claassen, W. C. Gause. 1995. Requirement for CTLA-4 counter receptors for IL-4, but not IL-10 elevations during a primary systemic in vivo immune response. J. Immunol 154:1078.
23. Kuchroo, V. K., M. P. Das, J. A. Brown, A. M. Ranger, S. C. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80:707.
24. Freeman, G. J., V. A. Boussiotis, A. Anumanthan, G. M. Bernstein, X. Ke, P. D. Rennert, G. S. Gray, J. G. Gribben, and L. M. Nadler. 1995. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523.
25. Natesan, M., Z. Razi-Wolf, and H. Reiser. 1996. Costimulation of IL-4 production by murine B7-1 and B7-2 molecules. J. Immunol. 156:2783.
26. + T cell and induce similar patterns of cytokine secretion in vitro. Int. Immunol. 7:891.
27. Hathcock, K. S., G. Laszlo, H. B. Dickler, J. Bradshaw, P. Linsley, and R. J. Hodes. 1993. Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262:905.
28. Razi-Wolf, Z., F. Galvin, G. Gary, and H. Reiser. 1993. Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor. Proc. Natl. Acad. Sci. USA 90:11182.
29. Lu, P., J. F. Urban, X. Chou, S. Chen, S. C. Morris, F. D. Finkelman, and W. C. Gause. 1996. CD40-mediated costimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production. J. Immunol. 156:3327.
30. Svetic, A., F. D. Finkelman, Y. C. Jian, C. W. Dieffenbach, D. E. Scott, K. F. McCarthy, A. D. Steinberg, and W. C. Gause. 1991. Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody. J. Immunol. 147:2391.
31. Gavett, S. H., D. O'Hearn, C. L. Karp, B. Schofield, F. D. Finkelman, and M. Wills-Karp. 1997. Blockade of the interleukin-4 receptor prevents pulmonary eosinophilia and airway hyperresponsiveness induced by antigen challenge in mice. Am. J. Physiol. 272:L253.
32. Lukacs, N. W., R. M. Stricter, S. W. Chensue, and S. L. Kunkel. 1994. Interleukin-4-dependent pulmonary cosinophil infiltration in a murine model of asthma. Am. J. Respir. Cell Mol. Biol. 10:526.
33. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse model of asthma. J. Exp. Med. 183:195.
34. Keane-Myers, A., P. S. Linsley, S. Chen, W. C. Gause, and M. Wills-Karp. 1997. B7-CD28/CTLA-4 costimulatory pathways are required for the development of Th2-mediated allergic airway responses to inhaled antigens. J. Immunol. 158:2042.
35. Tsuyuki, S., J. Tsuyuki, K. Einsle, M. Kopf, and A. J. Coyle. 1997. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J. Exp. Med. 185:1671.
36. Krinzman, S. J., G. T. De Sanctis, M. Cernadas, D. Mark, Y. Wang, J. Listman, L. Kobzik, C. Donovan, K. Nassr, I. Katona, D. C. Christiani, D. L. Perkins, and P. W. Finn. 1996. Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. J. Clin. Invest. 98:2693.
37. Harris, N., R. Peach, J. Naemura, P. S. Linsley, G. Le Gros, and F. Ronchese. 1997. CD80 costimulation is essential for the induction of airway eosinophilia. J. Exp. Med. 185:177.
38. Chvatchko, Y., M. H. Kosco-Vilbois, S. Herren, J. Lefort, and J. Bonnefoy. 1996. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J. Exp. Med. 184:2353.
39. Rot, A., M. Krieger, T. Brunner, S. C. Bischoff, T. J. Schall, and C. A. Dahinden. 1992. RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J. Exp. Med. 176:1489.
40. Jose, P. J., I. M. Adcock, D. A. Griffiths-Johnson, N. Berkman, T. N. C. Wells, T. J. Williams, and C. A. Power. 1994. Eostaxin: cloning of an eosinophil chemoattractant cytokine and increased mRNA expression in allergen-challenged guinea-pig lungs. Biochem. Biophys. Res. Commun. 205:788.
41. Dubey, C., M. Croft, and S. L. Swain. 1996. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J. Immunol. 157:3280.
42. Gause, W. C., P. Lu, X. Di Zhou, S. Chen, K. B. Madden, S. C. Morris, P. S. Linsley, F. D. Finkelman, and J. F. Urban. 1996. H. polygyrus: B7 independence of the secondary type 2 response. Exp. Parasitol. 84:264.
43. Greenwald, R. J., P. Lu, M. J. Halvorson, X. Zhou, S. Chen, K. B. Madden, P. J. Perrin, S. C. Morris, F. D. Finkelman, R. Peach, P. S. Linsley, J. F. Urban, Jr., and W. C. Gause. 1997. Effects of blocking B7-1 and B7-2 interactions during a type 2 in vivo immune response. J. Immunol. 158:4088.
44. Boussiotis, V. A., G. J. Freeman, J. G. Gribben, J. Daley, G. Gray, and L. M. Nadler. 1993. Activated human B lymphocytes express three CTLA4 binding counter-receptors which costimulate T cell activation. Proc. Natl. Acad. Sci. USA 90:11059.
45. Freeman, G. J., J. G. Gribben, V. A. Boussiotis, J. W. Ng, V. Restivo, L. Lombard, G. S. Gray, and L. M. Nadler. 1993. Cloning of B7-2: a CTLA4 counter-receptor that costimulates human T cell proliferation. Science 262:909.
46. Lenschow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233.
47. Gause, W. C., M. J. Halvorson, P. Lu, R. Greenwald, P. Linsley, J. F. Urban, and F. D. Finkelman. 1997. The function of costimulatory molecules and the development of IL-4-producing T cells. Immunol. Today 18:115.