Analysis of human immunodeficiency virus type 1 (HIV-1) variants and levels of infection in dendritic and T cells from symptomatic HIV-1-infected patients

Journal of General Virology

Volumn 79, Issue 2, 1998, Pages 247-257

  Patterson, S ^a   English, N R ^a   Longhurst, H ^b   Balfe, P ^c   Helbert, M ^b   Pinching, A J ^b   Knight, S C ^a  

^a NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DNA FLANKING REGION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONONUCLEAR CELL; PHYLOGENY; PRIORITY JOURNAL; PROVIRUS; T LYMPHOCYTE; VIRUS TRANSMISSION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0031974842     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-79-2-247     Document Type: Article

References (70)

1. Asjo, B., Albert, J., Karlsson, A., Morfeldt Manson, L., Biberfeld, G., Lidman, K. & Fenyo, E. M. (1986). Replicative properties of human immunodeficiency virus from patients with varying severity of HIV infection. Lancet ii, 660-662.
2. Bagasra, O. & Pomerantz, R. J. (1993). Human immunodeficiency virus type 1 provirus is demonstrated in peripheral blood monocytes in vivo -a study utilizing an in situ polymerase chain reaction. AIDS Research and Human Retroviruses 9, 69-76.
3. Bagasra, O., Seshamma, T., Oakes, J. W. & Pomerantz, R. J. (1993). High percentages of CD4-positive lymphocytes harbor the HIV-1 provirus in the blood of certain infected individuals. AIDS 1, 1419-1425.
4. Belsito, D. V., Sanchez, R., Baer, M. D., Valantine, F. & Thorbecke, G. J. (1984). Reduced Langerhans' cell Ia antigen and ATPase activity in patients with the acquired immunodeficiency syndrome. New England Journal of Medicine 310, 1279-1282.
5. Blauvelt, A., Clerici, M., Lucey, D. R., Steinberg, S. M., Yarchoan, R., Walker, R., Shearer, G. M. & Katz, S. I. (1995). Functional studies of epidermal Langerhans' cells and blood monocytes in HIV-infected person. Journal of Immunology 154, 3506-3515.
6. + T cells clonal expansion. Clinical and Experimental Immunology 88, 226-236.
7. + T cells. Science 257, 383-387.
8. Cameron, P. U., Lowe, M. G., Crowe, S. M., O'Doherty, U., Pope, M., Gezelter, S. & Steinman, R. M. (1994). Susceptibility of dendritic cells to HIV-1 infection in vitro. Journal of Leukocyte Biology 56, 257-165.
9. Caux, C., Dezutter-Dambuyant, C., Schmitt, D. & Banchereau, J. (1992). GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans' cells. Nature 360, 258-261
10. Chehimi, J., Prakash, K., Shanmugan, V., Collman, R., Jackson, S. J., Bandyopadhyay, S. & Starr, S. E. (1993). CD4 independent infection of human peripheral blood dendritic cells with isolates of human immunodeficiency virus type 1. Journal of General Virology 74, 1277-1275.
11. Cheng-Mayer, C., Seto, D., Tateno, M. & Levy, J. A. (1988). Biological features of HIV-1 that correlate with virulence in the host. Science 240, 80-82.
12. Chesebro, B., Wehrly, K., Nishio, J. & Perryman, S. (1992). Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T cell-tropic isolates: definition of critical amino acids involved in cell tropism. Journal of Virology 66, 6547-6554.
13. Dayhoff, M. O. (1979). Atlas of Protein Sequence and Structure, vol. 5, suppl. 3, 1978. Washington, DC : National Biomedical Research Foundation.
14. DeJong, J. J., De Ronde, A., Keulen, W., Tersmette, M. & Goudsmit, J. (1992). Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution. Journal of Virology 65, 6777-6780.
15. Deng, H., Lui, R., Ellmeier, W., Choe, S., Unutmaz, D., Burkhart, M., Dimarzio, P., Marmon, S., Sutton, R. E., Hill, C. M., Davis, C. B., Peiper, S. C., Schall, T. J., Littman, D. R. & Landau, N. R. (1996). Identification of a major co-receptor for primary isolates of HIV-1. Nature 381, 661-666.
16. Donaldson, Y. K., Bell, J. E., Holmes, E. C., Hughes, E. S., Brown, H. K. & Simmonds, P. (1994). In vivo distribution and cytopathology of variants of human immunodeficiency virus type 1 showing restricted sequence variability in the V3 loop. Journal of Virology 68, 5991-6005.
17. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381, 667-673.
18. Felsenstein, J. (1989). PHYLIP - phylogeny inference package (version 3.2). Cladistics 5, 164-166.
19. Fenyo, E. M., Morfeldt-Manson, L., Chiodi, F., Lind, B., Von Gegerfelt, A., Albert, J., Olausson, E. & Asjo, B. (1988). Distinct replicative and cytopathic characteristics of human immunodeficiency virus isolates. Journal of Virology 62, 4414-4419.
20. + dendritic cells are potent inducers of IFN-α in response to in vitro HIV-1 infection. Journal of Immunology 152, 4649-4662.
21. Fossum, S. (1989). Dendritic leukocytes: features of their in vivo physiology. Research in Immunology 140, 883-891.
22. Fouchier, R. A. M., Groenink, M., Kootstra, A., Tersmette, M., Huisman, H. G., Miedema, F. & Schuitemaker, H. (1992). Phenotype associated sequence variation in the third hyper variable domain of human immunodeficiency virus type 1 gp120 molecule. Journal of Virology 66, 3183-3187.
23. Fouchier, R. A., Brouwer, M., Broersen, S. A. & Schuitmaker, H. (1995). Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR. Journal of Clinical Microbiology 33, 906-911.
24. Freed, E. O., Myers, D. J. & Risser, R. (1991). Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain. Journal of Virology 65, 190-194.
25. Grez, M., Deitrich, U., Balfe, P., Von Breisen, H., Maniar, J. K., Mahambre, G., Delwart, E. L., Mullins, J. I. & Rubsamen-Waigmann, H. (1994). Genetic analysis of HIV-1/HIV-2 mixed infections in India reveals a recent spread of HIV-1 and HIV-2 from a single ancestor for each of these viruses. Journal of Virology 68, 2161-2168.
26. Granelli-Piperno, A., Moser, B., Pope, M., Chen, D., Wei, Y., Isdell, F., O'Doherty, U., Paxton, W., Koup, R., Mojsov, S., Bhardwaj, N., Clarke-Lewis, I., Baggiolini, M. & Steinman, R. M. (1996). Efficient interaction of HIV-1 with purified dendritc cells via multiple chemokine coreceptors. Journal of Experimental Medicine 184, 2433-2438.
27. Ho, D. D., Neumann, A. U., Perelson, A. S., Chen, V. W., Leonard, J. M. & Markowitz, M. (1995). Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123-126.
28. + lymphocytes of seropositive individuals. Journal of Infectious Diseases 164, 470-475.
29. Hwang, S. S., Boyle, J. J., Lyerly, H. K. & Cullen, B. R. (1991). Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253, 71-74.
30. Innocenti, P., Ottmann, M., Morand, P., Leclercq, P. & Seigneurin, J. M. (1992). HIV-1 in blood monocytes: frequency of detection of proviral DNA using PCR and comparison with the total CD4 count. AIDS Research and Human Retroviruses 8, 261-268.
31. Jurriaans, S., Dekker, J. T. & Deronde, A. (1992). HIV-1 viral DNA load in peripheral blood mononuclear cells from seroconverters and long-term infected individuals. AIDS 6, 635-641.
32. Kimura, M. (1983). The Neutral Theory of Molecular Evolution. Cambridge: Cambridge University Press.
33. Knight, S. C. & Patterson, S. (1997). Bone marrow-derived dendritic cells, infection with human immunodeficiency virus, and immunopathology. Annual Review of Immunology 15, 593-616.
34. Knight, S. C. & Stagg, A. J. (1993). Antigen-presenting cell types. Current Opinion in Immunology 8, 233-234.
35. Korber, B. & Myers, G. (1992). Signature pattern analysis: a method for analysing viral sequence relatedness. AIDS Research and Human Retroviruses 8, 1549-1560.
36. Langhoff, E., Terwilliger, E. F., Bos, H. J., Kalland, K. H., Pozansky, M. C., Bacon, O. M. L. & Haseltine, W. A. (1991). Replication of human immunodeficiency virus type 1 in primary dendritic cells. Proceedings of the National Academy of Sciences, USA 88, 7998-8002.
37. LaRosa, G. J., Davide, J. P., Weinhold, K., Waterbury, J. A., Profy, A. T., Lewis, J. A., Langlois, A. J., Dreesman, G. R., Boswell, R. N. & Shadduck, P. (1990). Conserved sequence and structural elements to the HIV-1 principal neutralizing determinant. Science 249, 932-935.
38. Livingstone, W. J., Moore, M., Innes, D., Bell, J. E. & Simmonds, P. (1996). Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1. Lancet 348, 649-654.
39. Ludewig, B., Holzeister, J., Rokes, K., Gentile, M., Becker, Y., Gelderblom, H. R. & Pauli, G. (1995). Replication pattern of human immunodeficiency virus type 1 in mature Langerhans' cells. Journal of General Virology 76, 1317-1325.
40. Macatonia, S. E., Patterson, S. & Knight, S. C. (1989). Suppression of immune responses by dendritic cells infected with HIV. Immunology 67, 285-289.
41. Macatonia, S. E., Lau, R., Patterson, S., Pinching, A. J. & Knight, S. C. (1990). Dendritic cell infection, depletion and dysfunction in HIV-infected individuals. Immunology 71, 38-45.
42. Macatonia, S. E., Gompels, M., Pinching, A. J., Patterson, S. & Knight, S. C. (1992). Antigen presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection. Immunology 75, 576-581.
43. Meyerhans, A., Cheynier, R., Albert, J., Seth, M., Kwok, S., Sninsky, J., Morfeldt Manson, L., Asjo, B. & Wain Hobson, S. (1989). Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations. Cell 58, 901-910.
44. Milich, L., Margolin, B. & Swanson, R. (1993). V3 loop of the human immunodeficiency virus type 1 Env protein: interpreting sequence variability. Journal of Virology 67, 5623-5634.
45. O'Brien, W. A., Koyanagi, Y., Namazie, A., Zhao, J-Q., Diagne, A., Idler, K., Zack, J. A. & Chen, I. S. Y. (1990). HIV-1 tropism can be determined by a region of gp120 outside the CD4 binding region. Nature 348, 69-73.
46. O'Doherty, U., Steinman, R. M., Peng, M., Cameron, P. U., Gezelter, S., Kopeloff, I., Swiggard, W. J., Pope, M. & Bhardwaj, N. (1993). Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. Journal of Experimental Medicine 178, 1067-1078.
47. Patterson, S. & Knight, S. C. (1987). Susceptibility of human peripheral blood dendritic cells to infection by human immunodeficiency virus. Journal of General Virology 68, 1177-1181.
48. Patterson, S., Macatonia, S. E., Gross, G., Bedford, P. & Knight, S. C. (1991a). HIV infection of peripheral blood dendritic cells. In Skin Langerhans (Dendritic) Cells in Virus Infections and AIDS, pp. 141-156. Edited by Y. Becker. Boston: Kluwer Academic.
49. Patterson , S., Gross, J., Bedford, P. A. & Knight, S. C. (1991b). Morphology and phenotype of dendritic cells from peripheral blood and their productive and non-productive infection with human immunodeficiency virus type 1. Immunology 72, 361-367.
50. Patterson, S., Gross, J., English, N., Stackpoole, A., Bedford, P. & Knight, S. C. (1995). CD4 expression on dendritic cells and their infection by human immunodeficiency virus. Journal of General Virology 76, 1155-1163.
51. Perelson, A. S., Neumann, A. U., Markowitz, M., Lenard, J. M. & Ho, D. D. (1996). HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span and viral generation time. Science 271, 1582-1586.
52. Pope, M., Betjes, M. G. H., Romani, N., Hirmand, H., Cameron, P. U., Hoffman, L., Gezelter, S., Schuler, G. & Steinman, R. M. (1994). Conjugates of dendritic cells and memory T lymphocytes facilitate productive infection with HIV-1. Cell 78, 389-398.
53. + T cells. Journal of Experimental Medicine 182, 2045-2056.
54. + progenitors in human bone marrow. Journal of Immunology 149, 2681-2688.
55. Roos, M. T. L., Lange, J. M. A., Goede, R. E. Y., Coutinho, R. A., Schellekens, P. T. A., Miedema, F. & Tersmette, M. (1992). Viral phenotype and immune response in primary human immunodeficiency type 1 infection. Journal of Infectious Diseases 165, 427-432.
56. Saitou, N. & Nei, M. (1987). The neighbor-joining method: a new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4, 406-425.
57. Salomon, B., Lores, P., Pioche, C., Racz, P., Jami, J. & Klatzman, D. (1994). Conditional ablation of dendritic cells in transgenic mice. Journal of Immunology 152, 537-548.
58. Schnittman, S. M., Psallidopoulos, M. C., Lane, H. C., Thomson, L., Baseler, M., Massari, F., Fox, C. H., Salzman, N. P. & Fauci, A. S. (1989). The reservoir for HIV-1 in human peripheral blood is a T cell that maintains expression of CD4. Science 245, 305-308.
59. Shioda, T., Levy, J. A. & Cheng-Mayer, C. (1991). Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature 349, 167-169.
60. Simmonds, P., Balfe, P., Peutherer, J. F., Ludlam, C. A., Bishop, J. O. & Leigh Brown, A. J. (1990). Human immunodeficiency virus-infected individuals contain provirus in small numbers in peripheral mononuclear cells and at low copy numbers. Journal of Virology 64, 864-872.
61. Soto-Ramirez, L. E., Renjifo, B., McLane, M. F., Marlink, R., O'Hara, C., Sutthent, R., Wasi, C., Vithayasai, P., Vithayasai, V., Apichartpiyakul, C., Auewarakul, P., Cruz, V. P., Chui, D.-S., Osathanondh, R., Mayer, K., Lee, T.-H. & Essex, M. (1996). HIV-1 Langerhans' cell tropism associated with heterosexual transmission of HIV. Science 271, 1291-1293.
62. Spira, A. I., Marx, P. A., Patterson, B. K., Mahoney, J., Koup, R. A., Wolinsky, S. M. & Ho., D. D. (1996). Cellular targets of infection and route of virus dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. Journal of Experimental Medicine 183, 215-225.
63. Tersmette, M. J., Lange, J. M., Goede, R. E. Y., De Wolf, F. Eeftink-Schattenkerk, J. K. M., Schellekens, P. T., Coutinho, R. A., Huisman, J. G., Goudsmi,t J. & Miedema, F. (1989). Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality. Lancet i, 983-985.
64. Thompson, J. D., Higgins, D. G. & Gibson, T. J. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice. Nucleic Acids Research 22, 4673-4680.
65. Wei, P., Ghosh, S. J., Taylor, M. E., Johnson, V. A., Emini, E. A., Deutsch, P., Lifson, J. D., Bonhoeffer, S., Nowak, M. A., Hahn, B. H., Saag, M. S. & Shaw, G. M. (1995). Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373, 117-122.
66. Westervelt, P., Gendelman, H. E. & Ratner, H. E. (1991). Identification of a determinant with the human immunodeficiency virus surface envelope glycoprotein critical for productive infection of primary monocytes. Proceedings of the National Academy of Sciences, USA 88, 3097-3101.
67. Winship, P. R. (1989). An improved method for direct|y sequencing PCR amplified material using dimethyl sulphoxide. Nucleic Acids Research 17, 1266.
68. Zhang, L. Q., Mackenzie, P., Cleland, A., Holmes, E. C., Brown, A. J. L. & Simmonds, P. (1993). Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection. Journal of Virology 67, 3345-3356.
69. + blood dendritic cells. Blood 86, 3295-3301.
70. Zhu, T., Mo, H., Wang, N., Nam, D. S., Cao, Y., Koup, R. A. & Ho, D. D. (1993). Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 261, 1179-1181.