Analysis of T-cell activation after bronchial allergen challenge in patients with atopic asthma

Journal of Allergy and Clinical Immunology

Volumn 101, Issue 5, 1998, Pages 699-708

  Lara Marquez, Maria L ^a,d   Deykin, Aaron ^a,d   Krinzman, Stephen ^a,c,d   Listman, James ^a,d   Israel, Elliot ^a,d   He, Hongzhen ^a,d   Christiani, David C ^c,d,e   Perkins, David L ^a,d   Finn, Patricia W ^a,b,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Allergen challenge; Asthma; CD45 R isoforms; Interleukin 2R; MHC class II; T helper cells

Indexed keywords

ALLERGEN; CD45 ANTIGEN; INTERLEUKIN 2 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADULT; ANTIGEN EXPRESSION; ARTICLE; ASTHMA; ATOPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HELPER CELL; HUMAN; HUMAN CELL; MALE; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; PROVOCATION TEST; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0031971111     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70180-0     Document Type: Article

References (41)

1. Dunnill M. The pathology of asthma, with special reference to changes in the bronchial mucosa. J Clin Pathol 1960;13:27-33.
2. Azzawi M, Bradley B, Jeffrey PK, Frew AJ, Wardlaw AJ, Knowles G, et al. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990;142:1407-13.
3. Corrigan C, Hartnell A, Kay A. T lymphocyte activation in acute severe asthma. Lancet 1988;1:1129-32.
4. Corrigan C, Hartnell A, Kay A. CD4 T lymphocyte activation in acute severe asthma: relationship to disease severity and atopic status. Am Rev Respir Dis 1990;141:970-7.
5. Walker C, Virchow J, Iff T, Bruijnzeel P, Blaser K. T cells and asthma, I: lymphocyte supopulation and activation in allergic and non-allergic asthma. Int Arch Allergy Appl Immunol 1991;94:241-3.
6. Robinson D, Hamid Q, Bentley A, Ying S, Kay B, Durnham S. Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993;92:313-24.
7. Virchow J, Walker C, Haffner D, Kortsik C, Werner P, Matthys H, et al. T cells and cytokines in bronchioalveolar lavage fluid after segmental allergen provocation in atopic asthma. Am J Respir Crit Care Med 1995;151:960-8.
8. Garssen J, Nijkamp H, van der Vliet M, van Loveren H. T-cell mediated induction of airway hyperreactivity in mice. Am Rev Respir Dis 1991;144:931-8.
9. Gavett S, Xiaoling C, Finkelman F, Wills-Karp M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 1994;10:587-93.
10. Krinzman S, De Sanctis GT, Cernadas M, Kobzick L, Christiani DL, Perkins DL, et al. T cell activation in a murine model of asthma. Am J Physiol 1996;271:L476-83.
11. Krinzman S, De Sanctis GT, Cernadas M, Mark D, Wang Y, Listman J, et al. Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. J Clin Invest 1996;98: 2693-9.
12. Ralph S, Thomas M, Morton C, Trowbridge I. Structural variants of human T200 glycoprotein (leukocyte-common antigen). EMBO J 1987;6:1251-7.
13. Morimoto C, Matsuyama T, Rudd C, Forsegren A, Letvin N, Schlossman S. Role of 2H4 molecule in the activation of suppressor inducer function. Eur J Immunol 1988;18:731-7.
14. Sanders M, Makgoba M, Sharrow SO, Stephany D, Springer A, Young H, et al. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3,CD2 and LFA-1) and three other molecules (UCHL1,CD29 and Pgp-1) and have enhanced IFN-γ production. J Immunol 1988;140:1401-7.
15. Swain SL, Bradley LM, Croft M, Tonkonogy S, Atkin G, Weinberg AD, et al. Helper T cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev 1991;123:115.
16. Croft M, Duncan D, Swain S. Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. J Exp Med 1992;176:1431-7.
17. Plebanski M, Saunders M, Burtles S, Crowe S, Hooper D. Primary and secondary human in vitro T-cell responses to soluble antigen are mediated by subsets bearing different CD45 isoforms. Immunology 1992;75:86-91.
18. Newman I, Wilkinson P. Locomotor responses of human CD45 lymphocyte subset: preferential locomotion of CD5RO+ lympho-cytes in response tro attractants and mitogens. Immunology 1993;78:92-8.
19. Mackay C. T-cell memory: the connection between function, phenotype and migration pathways. Immunol Today 1991;12:189-92.
20. Patel HR, Oshiba A, Jeppson JD, Gelfand EW. Differential expression of CD40 ligand on T cell subsets: implications for different roles of CD45RA+ and CD45RO+ cells in IgE production. J Immunol 1996;156:1781-7.
21. Nasert S, Burtchen N, Kussebi F, Millner M, Kroczeck R, Jung T, et al. Stimulation of IgE and IgA production by CD45RA T helper cells in atopic patients. J Immunol 1996;157:441-8.
22. Boyum A. Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol 1976; suppl 5:9-15.
23. Listman JL, Rimm IJ, Wang Y, Geller MC, Tang JC, Ho S, et al. Plasticity of the T cell receptor repertoire in TCR beta-chain transgenic mice. Cell Immunol 1996;167:44-55.
24. Perkins DL, Listman JL, Marshak-Rothstein A, Kozlow W, Kelley VR, Finn PW, et al. Restriction of the TCR repertoire inhibits the development of memory cells and prevents autoimmunity in Ipr mice. J Immunol 1996;156:4961-8.
25. Schauer U, Jung T, Heymanns J, Rieger CH. Imbalance of CD4 + CD45R+ and CD4 + CD29+ T helper cell subsets in patients with atopic diseases. Clin Exp Immunol 1991;83:25-9.
26. Gerblich A, Salick H, Schuyler M. Dynamic T cell changes in peripheral blood and bronchoalveolar lavage after antigen bronchoprovocation in asthmatics. Am Rev Respir Dis 1991;143:533-7.
27. De Rosse V, Rolla G, Bocca C, Ghio P, Bertoletti M, Baderna P, et al. Intercellular adhesion molecule-1 is upregulated on peripheral blood T lymphocyte subsets in dual asthmatic responders. J Clin Invest 1994;94:1840-5.
28. Walker C, Erhard B, Boer L, Hansel TT, Virchow J-C Jr. Allergic and nonallergic asthmatics have distinct patterns of T cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992;146:109-15.
29. Bois R, Kirby M, Balbi B, Saltini C, Crystal R. T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell antigen receptor. Am Rev Respir Dis 1992;145:1205-11.
30. Werfel S, Massey W, Lichtenstein L, Bochner B. Preferential recruitment of activated, memory T lymphocytes into skin chamber fluids during human cutaneous late-phase allergic reactions. J Allergy Clin Immunol 1995;96:57-65.
31. Akbar A, Terry L, Timms A, Beverly P, Janossy G. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 1988;140:2171-8.
32. Akbar A, Salmon M, Janossy G. The synergy between naive and memory cell during activation. Immunol Today 1991;12:184-8.
33. La Salle JM, Hafler DA. Review of T cell tolerance. FASEB J 1994;8:601-8.
34. Finn P, Kara C, Grusby M, Folsom V, Glimcher L. Upstream elements of the MHC class II E beta gene active in B cells. J Immunol 1991;146:4011-5.
35. Rothestein D, Yamada A, Schlossman S, Morimoto C. Cyclic regulation of CD45 isoform expression in a long term human CD4 + CD45RA+ T cell line. J Immunol 1991;146:1175-83.
36. Shanafelt M, Yssel H, Soderber C, Steinman L, Adelman DC, Peltz G, et al. Immunodeficiency and other clinical immunology: CD45 isoforms on human CD4+ T-cell subsets. J Allergy Clin Immunol 1996;98:433-40.
37. Zola H, Flego L, Macardle PJ, Donohoe PJ, Raford J, Roberton D. The CD45RO(p180, UCHL1) marker: complexity of expression in peripheral blood. Cell Immunol 1992;145:175-86.
38. low T cells in newborn blood. Biol Neonate 1996;69:128-32.
39. Johanisson A, Festin R. Phenotype transition of CD4+ T cells from CD45RA to CD45RO is accompanied by cell activation and proliferation. Cytometry 1995;19:343-52.
40. Kanegane H, Miyawaki T, Kato K, Yokoi T, Uhera T, Taniguchi Y. A novel subpopulation of CD45RA+ CD4+ T cells expressing IL-2 receptor alpha-chain (CD25) and having functionally transitional nature into memory cells. Int Immunol 1991;3:1349-56.
41. Wilson J, Djukanovic R, Howarth P, Holgate S. Lymphocyte activation in bronchoalvioalar and peripheral blood in atopic asthma. Am Rev Respir Dis 1992;145:958-60.