Stimulation of IgE and IgA production by CD45RA T helper cells in atopic patients

Journal of Immunology

Volumn 157, Issue 1, 1996, Pages 441-448

  Nasert, Solveig ^a   Burtchen, Nina ^a   Kussebi, Fatimah ^a   Millner, Martina ^a   Kroczek, Richard ^d   Jung, Thomas ^b   Schwinzer, Reinhard ^c   Wahn, Ulrich ^a   Renz, Harald ^a,e  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d ROBERT KOCH INSTITUTE   (Germany)

^e Research Building ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5;

ARTICLE; ATOPY; CONTROLLED STUDY; EFFECTOR CELL; GENE EXPRESSION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE FUNCTION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ALLERGENS; ANTIGENS, CD45; B-LYMPHOCYTES; CELL COMMUNICATION; CYTOKINES; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; LYMPHOCYTE COUNT; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0030003033     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Hanifin, M. J., and G. Rajka. 1980. Diagnostic features of atopic dermatitis. Acta Derm. Venereol. Suppl. 92:44.
2. + T lymphocytes in atopic patients. J. Immunol. 144:4651.
3. Vercelli, D., H. H. Jabara, R. P. Lauener, and R. S. Geha. 1990. IL-4 inhibits the synthesis of IFN-γ and induces the synthesis of IgE in human mixed lymphocyte cell cultures. J. Immunol. 144:570.
4. Rousset, F., J. Robert, M. Andary, J.-P. Bonnin, G. Souillet, I. Chretien, F. Briere, J. Pene, and J. E. de Vries. 1991. Shifts in interleukin-4 and interferon-γ production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis. J. Allergy Clin. Immunol. 87:58.
5. Maggi, E., P. Parronchi, R. Manetti, C. Simonelli, M.-P. Piccini, F. S. Rugiu, M. De Carli, M. Ricci, and S. Romagnani. 1992. Reciprocal regulatory effects of IFN-γ and IL-4 on the in vitro development of human Th1 and Th2 clones. J. Immunol. 148:2142.
6. Jujo, K., H. Renz, J. Abe, E. W. Gelfand, and D. Y. M. Leung. 1992. Decreased interferon-γ and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis. J. Allergy Clin. Immunol. 90:323.
7. - helper cells that secretes IL-2, IL-3, IL-4,and Interferon-γ. J. Exp. Med. 174:547.
8. + T helper cell subsets in patients with atopic diseases. Clin. Exp. Immunol. 83:25.
9. + T cells. Eur. J. Immunol. 19:771.
10. + CD45RA human T cells following polyclonal activation. Scand. J. Immunol 32:243.
11. Lewis, D. B., K. S. Prickett, A. Larsen, K. Grabstein, M. Weaver, and C. B. Wilson. 1988. restricted production of interleukin 4 by activated human T cells. Proc. Natl. Acad. Sci. USA 85:9743.
12. + T cell clones. J. Immunol. 143:907.
13. Horgan, K. J., G. A. Van Seventer, Y. Shimizu, and S. Shaw. 1990. Hyporesponsiveness of "naive" (CD45RA) human T cells to multiple receptor-mediated stimuli but augmentation of responses by co-stimuli. Eur. J. Immunol. 20:1111.
14. Morimoto, C., N. L. Letvin, A. W. Boyd, M. Hagan, M. Brown, M. M. Kornacki, and S. F. Schlossman. 1985. The isolation and characterization of the human helper inducer T cell subset. J. Immunol. 134:3762.
15. Sanders, M. E., M. W. Makgoha, C. H. June, H. A. Young, and S. Shaw. 1989. Enhanced responsivenes of human memory T cells to CD2 and CD3 receptor-mediated activation. Eur. J. Immunol. 19:803.
16. + T helper cells differing in kinetics and capabilities to produce interleukin 2 and interferon gamma can be defined by Leu-18 and UCHL1 monoclonal antibodies. Eur. J. Immunol. 18:1173.
17. Akbar, A. N., A. Timms, and G. Janossy. 1989. Cellular events during memory T-cell activation in vitro: the UCHLI (180,000 MW) determinant is newly synthesized after mitosis. Immunology 66:213.
18. Damle, N. K., A. L. Childs, and L. V. Doyle. 1987. Immunoregulatory T lymphocytes in man. J. Immunol. 139:1501.
19. Ehlers, S., and K. A. Smith. 1991. Differentiation of T cell lymphokine gene expression: the in vitro aquisition of T cell memory. J. Exp. Med. 173:25.
20. Bettens, F., C. Walker, J.-F. Gauchat, D. Gauchat, T. Wyss, and W. J. Pichler. 1989. Lymphokine gene expression related to CD4 T cell subset (CD45R/ CDw29) phenotype conversion. Eur. J. Immunol. 19:1569.
21. + T cell subsets. Cell. Immunol. 141:10.
22. + T cells synergize in response to alloantigens. Eur. J. Immunol. 21:2517.
23. Swain, S. L., G. Huston, S. Tonkonogy, and A. Weinberg. 1991. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147:2991.
24. Schwinzer, R., R. A. Franklin, J. Domenico, H. Renz, and E. W. Gelfand. 1992. Monoclonal antibodies directed to different epitopes in the CD3-TcR complex induce different states of competence in resting human T cells. J. Immunol. 148:1322.
25. Jung, T., G. Lack, U. Schauer, W. Überück, H. Renz, E. W. Gelfand, and C. H. L. Rieger. 1995. Decreased frequency of interferon-γ- and interleukin-2-producing cells in patients with atopic diseases measured at the single cell level. J. Allergy Clin. Immunol. 96:515.
26. Jung, T., U. Schauer, C. Heusser, C. Neumann, and C. H. L. Rieger. 1993. Detection of intracellular cytokines by flow cytometry. J. Immunol. Methods 159:197.
27. Lau-Schadendorf, S., and U. Wahn. 1991. Exposure to indoor allergens and development of allergy. Pedidtr. Allergy Immunol. 2:63.
28. Akbar, A. N., M. Salmon, and G. Janossy. 1991. The synergy between naive and memory T cells during activation. Immunol. Today 12:184.
29. Idzerka, R., C. March, B. Mosley, S. D. Lyman., T. Vanden Bos, M. B. Widmer, and L. S. Park. 1990. Human interleukin-4 receptor confers biological responsiveness and defines a novel receptor superfamily. J. Exp. Med. 171:861.
30. Mosley, B., M. P. Beckman, C. J. March, R. L. Iderza, S. D. Gimpel, T. Vandenbos, D. Friend, A. Alpert, J. Anderson, J. Jackson, J. M. Wignall, S. Smith, B. Gallis, J. E. Sims, D. Urdal, M. B. Widmer, D. Cosman, and L. S. Park. 1989. The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell 59:335.
31. Noelle, R. J., M. Roy, D. M. Shepherd, I. Stamenkovic, J. A. Ledbetter, and A. Aruffo. 1992. A novel ligand on activated T helper cells binds CD40 and transduces the signal for the cognate activation of B-cells. Proc. Natl. Acad. Sci. USA 89:6550.
32. Renz, H., B. D. Mazer, and E. W. Gelfand. 1990. Differential inhibition of T and B cell function in IL-4 dependent IgE production by cyclosporin A and methylprednisolone. J. Immunol. 145:3641.
33. Renz, H., K. H. Enssle, L. Lauffer, R. Kurrle, and E. W. Gelfand. 1995. Inhibition of allergen-induced IgE and IgGl production by soluble IL-4 receptor. Int. Arch. Allergy Immunol. 316:1018.
34. Punnonen, J., and J. E. De Vries. 1994. IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells. J. Immunol. 152: 1094.
35. Mosmann, T. R., and R. L. Coffmann. 1989. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 46:111.
36. + peripheral blood lymphocytes. J. Exp. Med. 179:857.
37. Renz, H., C. Brodie, K. Bradley, D. Y. M. Leung, and E. W. Gelfand. 1994. Enhancement of IgE production by anti-CD40 antibody in atopic patients. J. Allergy Clin. Immunol. 93:658.
38. Patel, H. R., A. Oshiba, J. D. Jeppson, and E. W. Gelfand. 1995. Regulation of IgE production by T cell subsets. J. Allergy Clin. Immmol. 95:334 (Abstr.).