메뉴 건너뛰기




Volumn 56, Issue 10, 1996, Pages 2306-2313

Oltipraz-mediated changes in aflatoxin B1 biotransformation in rat liver: Implications for human chemointervention

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; 3 METHYLCHOLANTHRENE; AFLATOXIN B1; CIPROFIBRATE; CYTOCHROME P450; OLTIPRAZ;

EID: 0029883290     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (45)
  • 2
    • 0027362312 scopus 로고
    • I Oltipraz. A laboratory and clinical review
    • Benson, A. B. I Oltipraz. A laboratory and clinical review J. Cell Biochem Suppl., 17F: 278-291, 1993
    • (1993) J. Cell Biochem Suppl. , vol.17 F , pp. 278-291
    • Benson, A.B.1
  • 4
    • 0026501721 scopus 로고
    • Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione
    • Lond.
    • Kensler, T. W , Groopman, J. D., Eaton, D. L., Curphey, T. J , and Roebuck, B. D. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione Carcinogenesis (Lond.), 13: 95-100, 1992
    • (1992) Carcinogenesis , vol.13 , pp. 95-100
    • Kensler, T.W.1    Groopman, J.D.2    Eaton, D.L.3    Curphey, T.J.4    Roebuck, B.D.5
  • 5
    • 0025925257 scopus 로고
    • 1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): Predictive role for short-term molecular dosimetry
    • 1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry Cancer Res., 51: 5501-5506, 1991
    • (1991) Cancer Res. , vol.51 , pp. 5501-5506
    • Roebuck, B.D.1    Liu, Y.L.2    Rogers, A.E.3    Groopman, J.D.4    Kensler, T.W.5
  • 7
    • 0025238457 scopus 로고
    • Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver
    • Davidson, N E., Egner, P. A., and Kensler, T. W. Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver Cancer Res., 50: 2251-2255, 1990
    • (1990) Cancer Res. , vol.50 , pp. 2251-2255
    • Davidson, N.E.1    Egner, P.A.2    Kensler, T.W.3
  • 8
    • 0027212969 scopus 로고
    • Quantitation of tissue-specific and sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones
    • Lond.
    • Meyer, D J., Harris, J M., Gilmore, K. S , Coles, B. Kensler, T. W., and Ketterer, B. Quantitation of tissue-specific and sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones. Carcinogenesis (Lond.), 14: 467-234, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 467-1234
    • Meyer, D.J.1    Harris, J.M.2    Gilmore, K.S.3    Coles, B.4    Kensler, T.W.5    Ketterer, B.6
  • 9
    • 0027497708 scopus 로고
    • Preferential increase of glutathione S-transferase class α transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones
    • Morel, F., Fardel, O., Meyer, D J., Langouet, S , Gilmore, K. S , Meunier, B., Tu, C-P. D., Kensler, T W., Ketterer, B., and Guillouzo, A Preferential increase of glutathione S-transferase class α transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones Cancer Res., 53: 231-234, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 231-234
    • Morel, F.1    Fardel, O.2    Meyer, D.J.3    Langouet, S.4    Gilmore, K.S.5    Meunier, B.6    Tu, C.-P.D.7    Kensler, T.W.8    Ketterer, B.9    Guillouzo, A.10
  • 10
    • 0017394357 scopus 로고
    • Ligandin heterogeneity: Evidence that the two non-identical subunits are the monomers of two distinct proteins
    • Bass, N M., Kirsch, R. E., Tuff, S. A., Marks, I., and Saunders, S. J. Ligandin heterogeneity: evidence that the two non-identical subunits are the monomers of two distinct proteins. Biochim. Biophys. Acta, 492. 163-175, 1977
    • (1977) Biochim. Biophys. Acta , vol.492 , pp. 163-175
    • Bass, N.M.1    Kirsch, R.E.2    Tuff, S.A.3    Marks, I.4    Saunders, S.J.5
  • 13
    • 0029048396 scopus 로고
    • Intermitted dosing with oltipraz relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases
    • Primiano, T , Egner, P. A., Sutter, T. R , Kelloff, G J., Roebuck, B. D., and Kensler, T. W. Intermitted dosing with oltipraz relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases. Cancer Res., 55: 4319-4324, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4319-4324
    • Primiano, T.1    Egner, P.A.2    Sutter, T.R.3    Kelloff, G.J.4    Roebuck, B.D.5    Kensler, T.W.6
  • 14
    • 0028212905 scopus 로고
    • Coordinate induction of glutathione S-transferase α, μ and π expression in murine liver after a single administration of oltipraz
    • Clapper, M L., Everley, L C., Strobel, L A , Townsend, A J , and Engstrom, P F. Coordinate induction of glutathione S-transferase α, μ and π expression in murine liver after a single administration of oltipraz. Mol. Pharmacol., 45: 469-474, 1994.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 469-474
    • Clapper, M.L.1    Everley, L.C.2    Strobel, L.A.3    Townsend, A.J.4    Engstrom, P.F.5
  • 15
    • 0001545268 scopus 로고
    • Aflatoxin carcinogenesis
    • H. Busch (ed), New York. Academic Press
    • Wogan, G Aflatoxin carcinogenesis. In: H. Busch (ed), Methods in Cancer Research, pp. 309-344. New York. Academic Press, 1973.
    • (1973) Methods in Cancer Research , pp. 309-344
    • Wogan, G.1
  • 18
    • 0025000688 scopus 로고
    • 1-8,9-epoxide and benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide
    • 1-8,9-epoxide and benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide. Toxicol Appl. Pharmacol., 105: 216-225, 1990.
    • (1990) Toxicol Appl. Pharmacol. , vol.105 , pp. 216-225
    • Ramsdell, H.S.1    Eaton, D.L.2
  • 21
    • 0023821353 scopus 로고
    • 1 hydroxylation by the pregnenolone-16α-carbonitrile-inducible form of rat liver microsomal cytochrome P-450
    • Lond.
    • 1 hydroxylation by the pregnenolone-16α-carbonitrile-inducible form of rat liver microsomal cytochrome P-450. Carcinogenesis (Lond.), 9: 2103-2108, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 2103-2108
    • Halvorson, M.R.1    Safe, S.H.2    Parkinson, A.3    Philips, T.D.4
  • 23
    • 0026614344 scopus 로고
    • 1-8,9-epoxide conjugating activity of two bacterially expressed α class glutathione S-transferase isozymes from mouse and rat
    • 1-8,9-epoxide conjugating activity of two bacterially expressed α class glutathione S-transferase isozymes from mouse and rat. Biochem. Biophys. Res. Commun., 188: 597-603, 1992.
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , pp. 597-603
    • Buetler, T.M.1    Slone, D.2    Eaton, D.L.3
  • 26
  • 27
    • 0025067417 scopus 로고
    • 1 carcinogenesis: Comparative kinetics of microsomal biotransformation
    • 1 carcinogenesis: comparative kinetics of microsomal biotransformation. Cancer Res., 50: 615-620, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 615-620
    • Ramsdell, H.S.1    Eaton, D.L.2
  • 28
    • 2642593241 scopus 로고
    • The suppression of aflatoxin carcinogenesis by oltipraz: Mechanisms and clinical opportunities
    • Kensler, T. W. The suppression of aflatoxin carcinogenesis by oltipraz: mechanisms and clinical opportunities. Proc. Am. Assoc. Cancer Res , 35. 696-697, 1994.
    • (1994) Proc. Am. Assoc. Cancer Res , vol.35 , pp. 696-697
    • Kensler, T.W.1
  • 29
    • 0025876040 scopus 로고
    • Hepatic glutathione S-transferases in mice fed on a diet containing the anticarcinogenic antioxidant butylated hydroxyanisole: Isolation of mouse glutathione S-transferase heterodimers by gradient elution of the glutathione-Sepharose affinity matrix
    • Hayes, J. D., Kerr, L A., Peacock, S D., Cronshaw, A. D., and McLellan, L. I Hepatic glutathione S-transferases in mice fed on a diet containing the anticarcinogenic antioxidant butylated hydroxyanisole: isolation of mouse glutathione S-transferase heterodimers by gradient elution of the glutathione-Sepharose affinity matrix Biochem. J., 277: 501-512, 1991.
    • (1991) Biochem. J. , vol.277 , pp. 501-512
    • Hayes, J.D.1    Kerr, L.A.2    Peacock, S.D.3    Cronshaw, A.D.4    McLellan, L.I.5
  • 30
    • 0026546972 scopus 로고
    • Complementary DNA cloning, messenger RNA expression and induction of α-class glutathione S-transferases in mouse tissues
    • Buetler, T. M., and Eaton, D. L Complementary DNA cloning, messenger RNA expression and induction of α-class glutathione S-transferases in mouse tissues Cancer Res., 52: 314-318, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 314-318
    • Buetler, T.M.1    Eaton, D.L.2
  • 31
    • 0024819308 scopus 로고
    • Isolation, characterization, and expression in Escherichia coli of two murine μ class glutathione S-transferase cDNAs homologous to the rat subunits 3 (Yb1) and 4 (Yb3)
    • Townsend, A. J., Goldsmith, M. E , Pickett, C. B., and Cowan, K. H. Isolation, characterization, and expression in Escherichia coli of two murine μ class glutathione S-transferase cDNAs homologous to the rat subunits 3 (Yb1) and 4 (Yb3). J. Biol. Chem., 264: 21582-21590, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 21582-21590
    • Townsend, A.J.1    Goldsmith, M.E.2    Pickett, C.B.3    Cowan, K.H.4
  • 33
    • 0028856209 scopus 로고
    • Induction of messenger RNA, protein and enzyme activity of drug metabolizing enzymes in rat liver by cytochrome P450 inducers, phenolic antoxidants and oltipraz
    • Buetler, T. M , Gallagher, E P., Wang, C., Stahl, D. L., Hayes, J. D., and Eaton, D. L. Induction of messenger RNA, protein and enzyme activity of drug metabolizing enzymes in rat liver by cytochrome P450 inducers, phenolic antoxidants and oltipraz. Toxicol. Appl. Pharmacol., 135: 45-57, 1995.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 45-57
    • Buetler, T.M.1    Gallagher, E.P.2    Wang, C.3    Stahl, D.L.4    Hayes, J.D.5    Eaton, D.L.6
  • 34
    • 0029080925 scopus 로고
    • The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic drug metabolizing and antioxidant enzymes in rat liver
    • Gallagher, E. P., Buetler, T. M , Wang, C , Stahl, D. L., and Eaton, D. L. The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic drug metabolizing and antioxidant enzymes in rat liver. Toxicol. Appl. Pharmacol., 134: 81-91, 1995.
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 81-91
    • Gallagher, E.P.1    Buetler, T.M.2    Wang, C.3    Stahl, D.L.4    Eaton, D.L.5
  • 36
    • 0024234855 scopus 로고
    • Clustal. A package for performing multiple sequence alignment on a microcomputer
    • Amst.
    • Higgins, D. G., and Sharp, P. M. Clustal. A package for performing multiple sequence alignment on a microcomputer. Gene (Amst.), 73: 237-244, 1988.
    • (1988) Gene , vol.73 , pp. 237-244
    • Higgins, D.G.1    Sharp, P.M.2
  • 37
    • 0027058697 scopus 로고
    • Amino acid sequence comparison, classification and phylogenetic relationship of glutathione S-transferases
    • Buetler, T. M., and Eaton, D. L. Amino acid sequence comparison, classification and phylogenetic relationship of glutathione S-transferases. Environ. Carcinog. Ecotoxicol. Rev., 10C: 181-203, 1992.
    • (1992) Environ. Carcinog. Ecotoxicol. Rev. , vol.10 C , pp. 181-203
    • Buetler, T.M.1    Eaton, D.L.2
  • 39
    • 0019741605 scopus 로고
    • Assays for differentiation of glutathione S-transferase
    • Habig, W. H., and Jakoby, W. B. Assays for differentiation of glutathione S-transferase. Methods Enzymol., 77: 398-405, 1981.
    • (1981) Methods Enzymol. , vol.77 , pp. 398-405
    • Habig, W.H.1    Jakoby, W.B.2
  • 41
    • 0027179679 scopus 로고
    • Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse
    • Nerurkar, P. V., Park, S. S., Thomas, P. E., Nims, R. W., and Lubet, R. A. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem. Pharmacol., 46: 933-943, 1993.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 933-943
    • Nerurkar, P.V.1    Park, S.S.2    Thomas, P.E.3    Nims, R.W.4    Lubet, R.A.5
  • 45
    • 0027337582 scopus 로고
    • 1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin
    • 1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin. Cancer Res., 53: 3887-3894, 1993
    • (1993) Cancer Res. , vol.53 , pp. 3887-3894
    • Hayes, J.D.1    Judah, D.J.2    Neal, G.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.