메뉴 건너뛰기




Volumn 63, Issue 3, 1998, Pages 101-113

Mouse embryonic stem cells with aberrant transforming growth factor β signalling exhibit impaired differentiation in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 0031927207     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.1998.6330101.x     Document Type: Article
Times cited : (31)

References (57)
  • 1
    • 0002582118 scopus 로고
    • The transforming growth factor β family in vertebrate embryogenesis
    • Nilsen-Hamilton M (ed) Wiley-Liss
    • Akhurst RJ (1994) The transforming growth factor β family in vertebrate embryogenesis. In: Nilsen-Hamilton M (ed) Growth factors and signal transduction in development. Wiley-Liss, pp 97-122
    • (1994) Growth Factors and Signal Transduction in Development , pp. 97-122
    • Akhurst, R.J.1
  • 2
    • 0025270339 scopus 로고
    • TGF beta in murine morphogenetic processes: The early embryo and cardiogenesis
    • Akhurst RJ, Lehnert SA, Faissner A, Duffle E (1980) TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development 108:645-656
    • (1980) Development , vol.108 , pp. 645-656
    • Akhurst, R.J.1    Lehnert, S.A.2    Faissner, A.3    Duffle, E.4
  • 3
    • 0020459571 scopus 로고
    • Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro
    • Bader D, Masaki T, Fischman DA (1982) Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol 95:763-770
    • (1982) J Cell Biol , vol.95 , pp. 763-770
    • Bader, D.1    Masaki, T.2    Fischman, D.A.3
  • 5
    • 0029806078 scopus 로고    scopus 로고
    • Regulation of transforming growth factor β- and activin-induced transcription by mammalian Mad proteins
    • Chen Y, Lebrun JJ, Vale W (1996) Regulation of transforming growth factor β- and activin-induced transcription by mammalian Mad proteins. Proc Natl Acad Sci USA 93:12992-12997
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12992-12997
    • Chen, Y.1    Lebrun, J.J.2    Vale, W.3
  • 10
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
    • Friedrich G, Soriano P (1991) Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5:1513-1523
    • (1991) Genes Dev , vol.5 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 11
    • 0024320450 scopus 로고
    • Use of BRL-conditioned medium in combination with feeder layers to isolate a diploid embryonal stem cell line
    • Handyside AH, O'Neill GT, Jones M, Hooper ML (1989) Use of BRL-conditioned medium in combination with feeder layers to isolate a diploid embryonal stem cell line. Roux's Arch Dev Biol 198:48-55
    • (1989) Roux's Arch Dev Biol , vol.198 , pp. 48-55
    • Handyside, A.H.1    O'Neill, G.T.2    Jones, M.3    Hooper, M.L.4
  • 12
    • 0023025366 scopus 로고
    • Transforming growth factor β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
    • Ignotz RA, Massagué J (1986) Transforming growth factor β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261: 4337-4345
    • (1986) J Biol Chem , vol.261 , pp. 4337-4345
    • Ignotz, R.A.1    Massagué, J.2
  • 13
    • 0028970392 scopus 로고
    • Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development
    • Johansson BM, Wile WV (1995) Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development. Mol Cell Biol 15:141-151
    • (1995) Mol Cell Biol , vol.15 , pp. 141-151
    • Johansson, B.M.1    Wile, W.V.2
  • 15
    • 0027977118 scopus 로고
    • Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos
    • Kispert A, Herrmann B (1994) Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev Biol 161:179-193
    • (1994) Dev Biol , vol.161 , pp. 179-193
    • Kispert, A.1    Herrmann, B.2
  • 18
    • 0026537831 scopus 로고
    • Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
    • Lin HY, Wang XF, Ng-Eaton K, Weinberg R, Lodish H (1992) Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68:775-785
    • (1992) Cell , vol.68 , pp. 775-785
    • Lin, H.Y.1    Wang, X.F.2    Ng-Eaton, K.3    Weinberg, R.4    Lodish, H.5
  • 19
    • 0030300115 scopus 로고    scopus 로고
    • MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signalling
    • Macias-Silva M, Abdollah S, Hoodless PA, Pirone R, Attisano L, Wrana JL (1996) MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signalling. Cell 87:1215-1224
    • (1996) Cell , vol.87 , pp. 1215-1224
    • Macias-Silva, M.1    Abdollah, S.2    Hoodless, P.A.3    Pirone, R.4    Attisano, L.5    Wrana, J.L.6
  • 20
    • 0016489816 scopus 로고
    • Differentiation of clonal lines of tertocarcinoma cells: Formation of embryoid bodies in vitro
    • Martin G, Evans MJ (1975) Differentiation of clonal lines of tertocarcinoma cells: Formation of embryoid bodies in vitro. Proc Natl Acad Sci USA 72:1441
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 1441
    • Martin, G.1    Evans, M.J.2
  • 21
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signalling: Receptors, transducers, and mad proteins
    • Massagué J (1996) TGFβ signalling: receptors, transducers, and mad proteins. Cell 85:947-950
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 22
    • 0029904671 scopus 로고    scopus 로고
    • Serine/threonine kinase receptors: Mediators of transforming growth factor beta family signals
    • Massagué J, Weis-Garcia F (1996) Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals. Cane Surv 27:41-64
    • (1996) Cane Surv , vol.27 , pp. 41-64
    • Massagué, J.1    Weis-Garcia, F.2
  • 23
    • 0025977578 scopus 로고
    • Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo
    • Millan FA, Denhez F, Kondaiah P, Akhurst RJ (1991) Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo. Development 111:131-143
    • (1991) Development , vol.111 , pp. 131-143
    • Millan, F.A.1    Denhez, F.2    Kondaiah, P.3    Akhurst, R.J.4
  • 24
    • 0030271736 scopus 로고    scopus 로고
    • Regulation of differentiation by TGFβ
    • Moses HL, Serra R (1996) Regulation of differentiation by TGFβ. Curr Opin Gen Dev 6:581-586
    • (1996) Curr Opin Gen Dev , vol.6 , pp. 581-586
    • Moses, H.L.1    Serra, R.2
  • 26
    • 0022529105 scopus 로고
    • Establishment of a differentiated mesodermal line P19EX cells expressing functional PDGF and EGF receptors
    • Mummery CL, Feijen A, van den Brink CE, Moolenaar WH, de Laat SW (1986) Establishment of a differentiated mesodermal line P19EX cells expressing functional PDGF and EGF receptors. Exp Cell Res 165:229-242
    • (1986) Exp Cell Res , vol.165 , pp. 229-242
    • Mummery, C.L.1    Feijen, A.2    Van Den Brink, C.E.3    Moolenaar, W.H.4    De Laat, S.W.5
  • 27
    • 0025339242 scopus 로고
    • Characteristics of embryonic stem cell differentiation: A comparison with two embryonal carcinoma cell lines
    • Mummery CL, Feijen A, Freund F, Shen S (1990) Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines. Cell Diff Dev 30:195-206
    • (1990) Cell Diff Dev , vol.30 , pp. 195-206
    • Mummery, C.L.1    Feijen, A.2    Freund, F.3    Shen, S.4
  • 28
    • 0027312323 scopus 로고
    • Type β transforming growth factors and activins in differentiating embryonal carcinoma cells, embryonic stem cells and early embryonic development
    • Mummery CL, van den Eijnden-van Raaij AJM (1993) Type β transforming growth factors and activins in differentiating embryonal carcinoma cells, embryonic stem cells and early embryonic development. Int J Dev Biol 37:169-182
    • (1993) Int J Dev Biol , vol.37 , pp. 169-182
    • Mummery, C.L.1    Van Den Eijnden-van Raaij, A.J.M.2
  • 29
    • 0003127690 scopus 로고
    • Production of completely ES cell-derived fetuses
    • (Joyner AL (ed).). IRL PRESS, Oxford
    • Nagy A, Rossant J (1993) Production of completely ES cell-derived fetuses. In "Gene targeting A Practical approach" (Joyner AL (ed).). IRL PRESS, Oxford
    • (1993) Gene Targeting A Practical Approach
    • Nagy, A.1    Rossant, J.2
  • 32
    • 0030579203 scopus 로고    scopus 로고
    • TGF-β receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    • Oshima M, Oshima H, Taketo MM (1996) TGF-β receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev Biol 179:297-302
    • (1996) Dev Biol , vol.179 , pp. 297-302
    • Oshima, M.1    Oshima, H.2    Taketo, M.M.3
  • 33
    • 0025325865 scopus 로고
    • Preimplantation embryos development in vitro: Cooperative interactions among embryos and role of growth factors
    • Paria BC, Dey SK (1990) Preimplantation embryos development in vitro: Cooperative interactions among embryos and role of growth factors. Proc Natl Acad Sci USA 87:4756-4760
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4756-4760
    • Paria, B.C.1    Dey, S.K.2
  • 34
    • 0025132988 scopus 로고
    • In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: Comparative studies with TGF beta 1 and beta 2
    • Pelton RW, Dickinson ME, Moses HL, Hogan BL (1990) In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development 110:609-620
    • (1990) Development , vol.110 , pp. 609-620
    • Pelton, R.W.1    Dickinson, M.E.2    Moses, H.L.3    Hogan, B.L.4
  • 35
    • 0026326375 scopus 로고
    • Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: Expression patterns suggest multiple roles during embryonic development
    • Pelton RW, Saxena B, Jones M, Moses HL, Gold LI (1991) Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol 115:1091-1105
    • (1991) J Cell Biol , vol.115 , pp. 1091-1105
    • Pelton, R.W.1    Saxena, B.2    Jones, M.3    Moses, H.L.4    Gold, L.I.5
  • 36
    • 0000116653 scopus 로고
    • The transforming growth factor-βs
    • Sporn MB, Roberts AB (eds) Springer-Verlag, Berlin
    • Roberts AB, Sporn MB (1990) The transforming growth factor-βs. In: Sporn MB, Roberts AB (eds) Peptide Growth Factors and their Receptors. Springer-Verlag, Berlin, pp 143-152
    • (1990) Peptide Growth Factors and Their Receptors , pp. 143-152
    • Roberts, A.B.1    Sporn, M.B.2
  • 37
    • 0028670622 scopus 로고
    • Expression of TGFβs and their receptors during implantation and organogenesis of the mouse embryo
    • Roelen BAJ, Lin HY, Knezevic V, Freund E, Mummery CL (1994) Expression of TGFβs and their receptors during implantation and organogenesis of the mouse embryo. Dev Biol 166:716-728
    • (1994) Dev Biol , vol.166 , pp. 716-728
    • Roelen, B.A.J.1    Lin, H.Y.2    Knezevic, V.3    Freund, E.4    Mummery, C.L.5
  • 38
    • 0030795214 scopus 로고    scopus 로고
    • Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development
    • Roelen BAJ, van Rooijen MA, Mummery CL (1997) Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development. Dev Dyn, 209:418-430
    • (1997) Dev Dyn , vol.209 , pp. 418-430
    • Roelen, B.A.J.1    Van Rooijen, M.A.2    Mummery, C.L.3
  • 40
    • 0028157458 scopus 로고
    • Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts
    • Savatier P, Huang S, Szekely L, Wiman KG, Samarut J (1994) Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. Oncogene 9:809-818
    • (1994) Oncogene , vol.9 , pp. 809-818
    • Savatier, P.1    Huang, S.2    Szekely, L.3    Wiman, K.G.4    Samarut, J.5
  • 41
    • 0030034110 scopus 로고    scopus 로고
    • Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
    • Savatier P, Lapillonne H, van Grunsven LA, Rudkin BB, Samarut J (1996) Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12:309-322
    • (1996) Oncogene , vol.12 , pp. 309-322
    • Savatier, P.1    Lapillonne, H.2    Van Grunsven, L.A.3    Rudkin, B.B.4    Samarut, J.5
  • 42
    • 0027249152 scopus 로고
    • Transforming growth factor β in the early mouse embryo: Implications for the regulation of muscle formation and implantation
    • Slager HG, Van Inzen W, Freund E, van den Eijnden-van Raaij AJM, Mummery CL (1993) Transforming growth factor β in the early mouse embryo: implications for the regulation of muscle formation and implantation. Dev Gen 14:212-224
    • (1993) Dev Gen , vol.14 , pp. 212-224
    • Slager, H.G.1    Van Inzen, W.2    Freund, E.3    Van Den Eijnden-van Raaij, A.J.M.4    Mummery, C.L.5
  • 43
    • 0027160793 scopus 로고
    • Secretion of transforming growth factor β isoforms by embryonic stem cells: Isoform and latency are dependent on direction of differentiation
    • Slager HG, Freund E, Bulting AMJ, Feijen A, Mummery CL (1993) Secretion of transforming growth factor β isoforms by embryonic stem cells: isoform and latency are dependent on direction of differentiation. J Cell Phys 156:247-256
    • (1993) J Cell Phys , vol.156 , pp. 247-256
    • Slager, H.G.1    Freund, E.2    Bulting, A.M.J.3    Feijen, A.4    Mummery, C.L.5
  • 44
    • 0023256867 scopus 로고
    • Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells
    • Smith AG, Hooper ML (1987) Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev Biol 121:1-9
    • (1987) Dev Biol , vol.121 , pp. 1-9
    • Smith, A.G.1    Hooper, M.L.2
  • 45
    • 0010472032 scopus 로고
    • Monoclonal antibody defining a stage-specific mouse embryonic antigen, SSEA-1
    • Solter I, Knowles BB (1978) Monoclonal antibody defining a stage-specific mouse embryonic antigen, SSEA-1. Proc Natl Acad Sci USA 75:5565-5569
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 5565-5569
    • Solter, I.1    Knowles, B.B.2
  • 47
    • 0025678482 scopus 로고
    • Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in ES cells
    • te Riele H, Maandag ER, Clarke A, Hooper M, Berns A (1990) Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in ES cells. Nature 348:649-651
    • (1990) Nature , vol.348 , pp. 649-651
    • Te Riele, H.1    Maandag, E.R.2    Clarke, A.3    Hooper, M.4    Berns, A.5
  • 49
    • 0029944441 scopus 로고    scopus 로고
    • Signalling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors
    • ten Dijke P, Miyazono K, Heldin CH (1996) Signalling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr Opin Cell Biol 8:139-145
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 139-145
    • Ten Dijke, P.1    Miyazono, K.2    Heldin, C.H.3
  • 50
    • 0024556159 scopus 로고
    • Production of insulin-like growth factors, platelet-derived growth factor, and transforming growth factors and their role in the density-dependent growth regulation of a differentiated embryonal carcinoma cell line
    • van Zoelen EJJ, Koornneef I, Holthuis JCM, Ward-van Oostwaard TMJ, Feijen A, de Poorter TL, Mummery CL, van Buul-Offers SC (1989) Production of insulin-like growth factors, platelet-derived growth factor, and transforming growth factors and their role in the density-dependent growth regulation of a differentiated embryonal carcinoma cell line. Endocrinology 124:2029-2041
    • (1989) Endocrinology , vol.124 , pp. 2029-2041
    • Van Zoelen, E.J.J.1    Koornneef, I.2    Holthuis, J.C.M.3    Ward-van Oostwaard, T.M.J.4    Feijen, A.5    De Poorter, T.L.6    Mummery, C.L.7    Van Buul-Offers, S.C.8
  • 51
    • 0029131403 scopus 로고
    • Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppresser activity in replication error-positive colon carcinoma
    • Wang J, Sun LZ, Myerhoff L, Wang X, Gentry LE, Yang J, Liang J, Zborowska E, Markowitz S, Willson JKV, Brattain MG (1995) Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppresser activity in replication error-positive colon carcinoma. J Biol Chem 270:22044-22049
    • (1995) J Biol Chem , vol.270 , pp. 22044-22049
    • Wang, J.1    Sun, L.Z.2    Myerhoff, L.3    Wang, X.4    Gentry, L.E.5    Yang, J.6    Liang, J.7    Zborowska, E.8    Markowitz, S.9    Willson, J.K.V.10    Brattain, M.G.11
  • 52
    • 0030040061 scopus 로고    scopus 로고
    • Developmentally regulated gene expression of thrombomodulin in postimplantation mouse embryos
    • Weiler-Guettler H, Aird WC, Rayburn H, Husain M, Rosenberg RD (1996) Developmentally regulated gene expression of thrombomodulin in postimplantation mouse embryos. Development 122:2271-2281
    • (1996) Development , vol.122 , pp. 2271-2281
    • Weiler-Guettler, H.1    Aird, W.C.2    Rayburn, H.3    Husain, M.4    Rosenberg, R.D.5
  • 53
    • 0031957450 scopus 로고    scopus 로고
    • G1-phase regulators, cyclin D1, cyclin D2 and cyclin D3: Up-regulation at gastrulation and dynamic expression during neuralation
    • in press
    • Wianny F, Real FX, Mummery CL, Van Rooijen M, Lahti J, Samarut J, Savatier P (1998) G1-phase regulators, cyclin D1, cyclin D2 and cyclin D3: up-regulation at gastrulation and dynamic expression during neuralation. Dev Dyn (in press)
    • (1998) Dev Dyn
    • Wianny, F.1    Real, F.X.2    Mummery, C.L.3    Van Rooijen, M.4    Lahti, J.5    Samarut, J.6    Savatier, P.7
  • 56
    • 0029842713 scopus 로고    scopus 로고
    • MAD-related proteins in TGF-β signalling
    • Wrana JL, Attisano L (1996) MAD-related proteins in TGF-β signalling. Trends Genet 12:493-496
    • (1996) Trends Genet , vol.12 , pp. 493-496
    • Wrana, J.L.1    Attisano, L.2
  • 57
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-β response
    • Zhang Y, Feng X-H, Wu RY, Derynck R (1996) Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383:168-2108
    • (1996) Nature , vol.383 , pp. 168-2108
    • Zhang, Y.1    Feng, X.-H.2    Wu, R.Y.3    Derynck, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.