The DNA damaging drug cyproterone acetate causes gene mutations and induces glutathione-S-transferase P in the liver of female Big Blue® transgenic F344 rats

Carcinogenesis

Volumn 19, Issue 2, 1998, Pages 241-245

  Krebs, O ^a   Schafer B ^b   Wolff, Th ^b   Oesterle, D ^b   Deml, E ^b   Sund, M ^b   Favor, J ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYPROTERONE ACETATE; GLUTATHIONE TRANSFERASE; PHOSPHORUS 32;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOSE RESPONSE; DRUG DNA INTERACTION; ENZYME INDUCTION; FEMALE; GENE MUTATION; MITOGENESIS; MUTAGEN TESTING; MUTATION RATE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SPONTANEOUS MUTATION; STATISTICAL ANALYSIS; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CYPROTERONE ACETATE; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; FEMALE; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS; MUTAGENICITY TESTS; MUTAGENS; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344;

EID: 0031927041     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.2.241     Document Type: Article

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