-
1
-
-
0003895129
-
-
Her Majesty's Stationary Office, London, UK
-
Committee on Safety of Medicines (1972) Carcinogenicity Tests of Oral Contraceptives. Her Majesty's Stationary Office, London, UK.
-
(1972)
Carcinogenicity Tests of Oral Contraceptives
-
-
-
2
-
-
0018370444
-
Liver tumors and steroid hormones in rats and mice
-
Schuppler, J. and Günzel, P. (1979) Liver tumors and steroid hormones in rats and mice. Arch. Toxicol., 2, 181-195.
-
(1979)
Arch. Toxicol.
, vol.2
, pp. 181-195
-
-
Schuppler, J.1
Günzel, P.2
-
3
-
-
0018817695
-
Adaptive response of rat liver to the gestagen and anti-androgen cyproterone acetate and other inducers. II. Induction of liver growth
-
Schulte-Hermann, R., Hoffmann, V., Parzefall, W., Kallenbach, M., Gerhardt, A. and Schuppler, J. (1980) Adaptive response of rat liver to the gestagen and anti-androgen cyproterone acetate and other inducers. II. Induction of liver growth. Chem.-Biol. Interactions, 31, 287-300.
-
(1980)
Chem.-Biol. Interactions
, vol.31
, pp. 287-300
-
-
Schulte-Hermann, R.1
Hoffmann, V.2
Parzefall, W.3
Kallenbach, M.4
Gerhardt, A.5
Schuppler, J.6
-
4
-
-
0027217590
-
Cyproterone acetate generates DNA adducts in rat liver and in primary rat hepatocyte cultures
-
Topinka, J., Andrae, U., Schwarz, L.R. and Wolff, T. (1993) Cyproterone acetate generates DNA adducts in rat liver and in primary rat hepatocyte cultures. Carcinogenesis, 14, 423-427.
-
(1993)
Carcinogenesis
, vol.14
, pp. 423-427
-
-
Topinka, J.1
Andrae, U.2
Schwarz, L.R.3
Wolff, T.4
-
5
-
-
0028864079
-
Accumulation and persistence of DNA adducts of the synthetic steroid cyproterone acetate in rat liver
-
Werner, S., Topinka, J., Wolff, T. and Schwarz, L.R. (1995) Accumulation and persistence of DNA adducts of the synthetic steroid cyproterone acetate in rat liver. Carcinogenesis, 16, 2369-2372.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2369-2372
-
-
Werner, S.1
Topinka, J.2
Wolff, T.3
Schwarz, L.R.4
-
6
-
-
9344263900
-
Formation of DNA adducts of the synthetic steroid cyproterone acetate in hepatocytes of man, rats and pigs and in mouse liver
-
Werner, S., Topinka, J., Kunz, S., Beckurts, T., Heidecke, C.D., Wolff, T. and Schwarz, L.R. (1995) Formation of DNA adducts of the synthetic steroid cyproterone acetate in hepatocytes of man, rats and pigs and in mouse liver. Naunyn-Schmiedeberg's Arch. Pharmacol., 351 (Suppl.), R44.
-
(1995)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.351
, Issue.SUPPL.
-
-
Werner, S.1
Topinka, J.2
Kunz, S.3
Beckurts, T.4
Heidecke, C.D.5
Wolff, T.6
Schwarz, L.R.7
-
7
-
-
0028979550
-
Identification of 3α-hydroxy-cyproterone acetate as a metabolite of cyproterone acetate in the bile of female rats and the potential of this and other already known or putative metabolites to form DNA adducts in vitro
-
Kerdar, R.S., Baumann, A., Brudny-Klöppel, M., Biere, H., Blode, H. and Kuhnz, W. (1995) Identification of 3α-hydroxy-cyproterone acetate as a metabolite of cyproterone acetate in the bile of female rats and the potential of this and other already known or putative metabolites to form DNA adducts in vitro. Carcinogenesis, 16, 1835-1841.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1835-1841
-
-
Kerdar, R.S.1
Baumann, A.2
Brudny-Klöppel, M.3
Biere, H.4
Blode, H.5
Kuhnz, W.6
-
8
-
-
0026598408
-
Cyproterone acetate induces DNA damage in cultured rat hepatocytes and preferentially stimulates DNA synthesis in γ-glutamyltranspeptidase-positive cells
-
Neumann, I., Thierau, D., Andrae, U., Greim, H. and Schwarz, L.R. (1992) Cyproterone acetate induces DNA damage in cultured rat hepatocytes and preferentially stimulates DNA synthesis in γ-glutamyltranspeptidase-positive cells. Carcinogenesis, 13, 373-378.
-
(1992)
Carcinogenesis
, vol.13
, pp. 373-378
-
-
Neumann, I.1
Thierau, D.2
Andrae, U.3
Greim, H.4
Schwarz, L.R.5
-
9
-
-
0028800239
-
In vitro mutagenicity studies on cyproterone acetate using female rat hepatocytes for metabolic activation and as indicator cells
-
Kasper, P., Tegethoff, K. and Mueller, L. (1995) In vitro mutagenicity studies on cyproterone acetate using female rat hepatocytes for metabolic activation and as indicator cells. Carcinogenesis, 16, 2309-2314.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2309-2314
-
-
Kasper, P.1
Tegethoff, K.2
Mueller, L.3
-
10
-
-
0029059097
-
DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate
-
Martelli, A, Mattioli, F., Fazio, S., Andrae, U. and Brambilla, G. (1995) DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate. Carcinogenesis, 16, 1265-1269.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1265-1269
-
-
Martelli, A.1
Mattioli, F.2
Fazio, S.3
Andrae, U.4
Brambilla, G.5
-
11
-
-
0028170840
-
The genotoxic potential in vitro and in vivo of the allyl benzene etheric oils estragole, basil oil and trans-anethole
-
Müller, K., Kasper, P., Müller-Tegethoff, K. and Petr, T. (1994) The genotoxic potential in vitro and in vivo of the allyl benzene etheric oils estragole, basil oil and trans-anethole. Mutat. Res., 325, 129-136.
-
(1994)
Mutat. Res.
, vol.325
, pp. 129-136
-
-
Müller, K.1
Kasper, P.2
Müller-Tegethoff, K.3
Petr, T.4
-
12
-
-
0028304672
-
Recommendations for the performance of UDS tests in vitro and in vivo
-
Madle, S., Dean, S.W., Andrae, U. et al. (1994) Recommendations for the performance of UDS tests in vitro and in vivo. Mutat. Res., 312, 263-285.
-
(1994)
Mutat. Res.
, vol.312
, pp. 263-285
-
-
Madle, S.1
Dean, S.W.2
Andrae, U.3
-
13
-
-
0020397479
-
Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
-
Mirsalis, J.C., Tyson, C.K. and Butterworth, B.E. (1982) Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ. Mutagen., 4, 553-562.
-
(1982)
Environ. Mutagen.
, vol.4
, pp. 553-562
-
-
Mirsalis, J.C.1
Tyson, C.K.2
Butterworth, B.E.3
-
14
-
-
0021867621
-
Concomitant observations of UDS in the liver and micronuclei in the bone marrow of rats exposed to cyclophosphamide or 2-acetylaminofluorene
-
Ashby, J. and Beije, B. (1985) Concomitant observations of UDS in the liver and micronuclei in the bone marrow of rats exposed to cyclophosphamide or 2-acetylaminofluorene. Mutat. Res., 150, 383-392.
-
(1985)
Mutat. Res.
, vol.150
, pp. 383-392
-
-
Ashby, J.1
Beije, B.2
-
15
-
-
0022372389
-
Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment
-
Mirsalis, J.S., Tyson, K.C., Loh, E.N., Steinmetz, K.L., Bakke, J.P., Hamilton, C.M., Spak, D.K. and Spalding, J.W. (1985) Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment. Carcinogenesis, 6, 1521-1524.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1521-1524
-
-
Mirsalis, J.S.1
Tyson, K.C.2
Loh, E.N.3
Steinmetz, K.L.4
Bakke, J.P.5
Hamilton, C.M.6
Spak, D.K.7
Spalding, J.W.8
-
16
-
-
0020526856
-
Influence of intestinal bacteria, sex of animal, and position of the nitro group on the hepatic genotoxicity of nitrotoluene isomers in vivo
-
Doolittle, D.J., Sherrill, J.M. and Butterworth, B.E. (1983) Influence of intestinal bacteria, sex of animal, and position of the nitro group on the hepatic genotoxicity of nitrotoluene isomers in vivo. Cancer. Res., 43, 2836-2842.
-
(1983)
Cancer. Res.
, vol.43
, pp. 2836-2842
-
-
Doolittle, D.J.1
Sherrill, J.M.2
Butterworth, B.E.3
-
17
-
-
0026000368
-
Gene specific DNA repair
-
Bohr, V.A. (1991) Gene specific DNA repair. Carcinogenesis, 12, 1983-1992.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1983-1992
-
-
Bohr, V.A.1
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