Chronic ethanol treatment decreases [3H] epibatidine and [3H]nicotine binding and differentially regulates mRNA levels of nicotinic acetylcholine receptor subunits expressed in M10 and SH-SY5Y neuroblastoma cells

Journal of Neurochemistry

Volumn 70, Issue 3, 1998, Pages 1134-1142

  Gorbounova, Olga ^a   Svensson, Anne Lie ^a   Jönsson, Patrik ^a   Mousavi, Malahat ^a   Miao, Hui ^a   Hellström Lindahl, Eva ^a   Nordberg, Agneta ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ethanol; M10 cells; mRNA; Nicotinic receptor subtypes; SH SY5Y neuroblastoma cells; 3H Epibatidine; 3H Nicotine

Indexed keywords

ALCOHOL; CHOLINERGIC RECEPTOR; EPIBATIDINE; MESSENGER RNA; NICOTINE; NICOTINIC RECEPTOR; TRITIUM;

ALCOHOLISM; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DEPENDENCE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIGAND BINDING; MOUSE; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RECEPTOR BINDING; RNA ANALYSIS; SMOKING;

ANIMALIA; TRITIUM;

EID: 0031915934     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70031134.x     Document Type: Article

References (59)

1. Bencherif M., Fowler K., Lukas R. J., and Lippiello P. M. (1995) Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain. J. Pharmacol. Exp. Ther. 275, 987-994.
2. Bien T. H. and Burge R. (1990) Smoking and drinking: a review of the literature. Int. J. Addict. 25, 1429-1454.
3. Blomqvist O., Söderpalm B., and Engel J. A. (1992) Ethanol-induced locomotor activity: involvement of central nicotinic acetylcholine receptors? Brain Res. Bull. 29, 173-178.
4. Blomqvist O., Ericson M., Johnson D. H., Engel J. A., and Söderpalm B. (1996) Voluntary ethanol intake in the rat: effects of nicotine acetylcholine receptor blockade or subchronic nicotine treatment. Eur. J. Pharmacol. 314, 257-267.
5. Burnet P. W. J., Eastwood S. L., and Harrison P. J. (1994) Detection and quantitation of 5-HT 1A and 5-HT 2A receptor mRNAs in human hippocampus using reverse transcriptase-polymerase chain reaction (RT-PCR) technique and their correlation with binding site densities and age. Neurosci. Lett. 178, 85-89.
6. Carmody T. P., Brishetto C. S., Matarazzo J. D., O'Donnel R. P., and Conner W. E. (1985) Co-occurrent use of cigarettes, alcohol, and coffee in healthy, community-living men and women. Health Psychol. 4, 323-335.
7. Chomczynski P. and Sacchi N. (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
8. Collins A. C. (1996) The nicotinic cholinergic receptor as a potential site of ethanol action, in Pharmacological Effects of Ethanol on the Nervous System (Deitrich R. A. and Erwin V. G., eds), pp. 95-115. CRC Press, New York.
9. Collins A. C., Burch J. B., deFiebre C. M., and Marks M. J. (1988) Tolerance to and cross tolerance between ethanol and nicotine. Pharmacol. Biochem. Behav. 29, 365-373.
10. Collins A. C., Romm E., Selvaag S., Turner S., and Marks M. J. (1993) A comparison of the effects of chronic nicotine infusion on tolerance to nicotine and cross-tolerance to ethanol in long-and short-sleep mice. J. Pharmacol. Exp. Ther. 266, 1390-1397.
11. deFiebre C. M. and Collins A. C. (1993) A comparison of the development of tolerance to ethanol and cross-tolerance to nicotine after chronic ethanol treatment in long- and short-sleep mice. J. Pharmacol. Exp. Ther. 266, 1398-1406.
12. deFiebre C. M. and Meyer E. M. (1995) Ethanol affects the function of nicotine receptor subtypes expressed in Xenopus oocytes. (Abstr.) Alcohol. Clin. Exp. Res. 19, 504.
13. deFiebre C. M. and Meyer E. M. (1996) The α7 neuronal nicotinic receptor subtype is inhibited by ethanol. (Abstr.) Alcohol. Clin. Exp. Res. 20, 308.
14. Forman S. A., Righi D. L., and Miller K. W. (1989) Ethanol increases agonist affinity for nicotinic receptors from Torpedo. Biochim. Biophys. Acta 987, 95-103.
15. Fornasari D., Chini B., Tarroni P., and Clementi F. (1990) Molecular cloning of human neuronal nicotinic receptor α3-subunit. Neurosci. Lett. 111, 351-356.
16. Freund R. K. and Palmer M. R. (1997) Ethanol depression of cerebellar Purkinje neurons firing involves nicotinic acetylcholine receptors. Exp. Neurol. 143, 319-322.
17. Gerzanich V., Peng X., Wang F., Wells G., Anand R., Fletcher S., and Lindstrom J. (1995) Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic aceylcholine receptors. Mol. Pharmacol. 48, 774-782.
18. Gopalakrishnan M., Buisson B., Touma E., Giordano T., Campell J. E., Hu I. C., Donelly-Roberts D., Arneric S. P., Bertrand D., and Sullivan J. P. (1995) Stable expression and pharmacological properties of the human α7 nicotinic receptor. Eur. J. Pharmacol. 290, 237-246.
19. Griffiths R., Bigelow R., and Liebson I. (1976) Facilitation of human tobacco self-administration by ethanol: a behavioral analysis. J. Exp. Anal. Behav. 25, 279-292.
20. Guizzetti M. and Costa L. G. (1996) Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol. J. Neurochem. 67, 2236-2245.
21. Habecker B. A. and Nathanson N. M. (1992) Regulation of muscarinic acetylcholine receptor mRNA expression by activation of homologous and heterologous receptors. Proc. Natl. Acad. Sci. USA 89, 5035-5038.
22. Hellström-Lindahl E., Winblad B., and Nordberg A. (1993) Muscarinic and nicotinic receptor changes in the cortex and thalamus of brains of chronic alcoholics. Brain Res. 620, 42-48.
23. Henningfield J. E., Chait L. D., and Griffiths R. R. (1983) Cigarette smoking and subjective response in alcoholics: effect of pentobarbital. Clin. Pharmacol. Ther. 33, 806-812.
24. Henningfield J. E., Chait L. D., and Griffiths R. R. (1984) The effect of chronic ethanol in cigarette smoking by volunteers without history of alcoholism. Psychopharmacology 92, 1-5.
25. Hu G., Querimit L. A., Downing L. A., and Charness M. E. (1993) Ethanol differentially increases α2-adrenergic and muscarinic acetylcholine receptor gene expression on NG108-15 cells. J. Biol. Chem. 31, 23441-23447.
26. Hu X. J., Follesa P., and Ticku M. K. (1996) Chronic ethanol treatment produces a selective upregulation of the NMDA receptor subunit gene expression in mammalian cultured cortical neurons. Mol. Brain Res. 36, 211-218.
27. Huganir R. L., Delour A. H., Greengard P., and Hess G. P. (1986) Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature 321, 774-776.
28. Istvan J. and Matarazzo J. D. (1984) Tobacco, alcohol and caffeine use: a review of their relationship. Psychol. Bull. 95, 301-326.
29. Krebs H. A., Freedland R. A., Hems R., and Stubbs M. (1969) Inhibition of hepatic gluconeogenesis by ethanol. Biochem. J. 112, 117-124.
30. Larsson C., Simonsson P., Caron M., and Alling C. (1996) Long-term exposure to ethanol increases the number and function of muscarinic M1 receptors in human neuroblastoma cells. J. Pharmacol. Exp. Ther. 278, 313-319.
31. Li C., Peoples R. W., and Weight F. F. (1994) Alcohol action on neuronal membrane receptor: evidence for a direct interaction with the receptor protein. Proc. Natl. Acad. Sci. USA 91, 8200-8204.
32. Little H. J. (1991) Mechanisms that may underlie the behavioural effects of ethanol. Prog. Neurobiol. 36, 171-194.
33. Liu C., Nordberg A., and Zhang X. (1996) Differential co-expression of nicotinic acetylcholine receptor α4 and β2 subunit genes in various regions of rat brain. Neuroreport 7, 1645-1649.
34. Lukas R. J., Norman S. A., and Lucero L. (1993) Characterization of nicotinic acetylcholine receptors expressed by cells of the SH-SY5Y human neuroblastoma clonal line. Mol. Cell. Neurosci. 4, 1-12.
35. Luo J., West J. R., and Pantazis N. J. (1996) Ethanol exposure reduces the density of the low-affinity nerve growth factor receptor (p75) on pheochromocytoma (PC12) cells. Brain Res. 737, 34-44.
36. Madhok T. C., Matta S. G., and Sharp B. M. (1995) Nicotine regulates nicotinic cholinergic receptors and subunit mRNAs in PC12 cells through protein kinase A. Mol. Brain Res. 32, 143-150.
37. Marks M., Pauly J., Gross S. D., Deneris E. S., Herman-Borgmeyer I., Heinemann S. F., and Collins A. C. (1992) Nicotine binding and nicotinic receptor subunit mRNA after chronic nicotine treatment. J. Neurosci. 12, 2765-2784.
38. Mello N. K., Mendelson J. H., and Palmieri S. L. (1987) Cigarette smoking by women: interactions with alcohol use. Psychopharmacology 93, 8-15.
39. Miles M. F., Diaz J. E., and DeGuzman V. (1992) Ethanol-responsive gene expression in neural cell cultures. Biochim. Biophys. Acta 1138, 268-274.
40. Nagata K., Aistrup G. L., Huang C.-S., Marszalec W., Song J.-H., Yej J. Z., and Narahashi T. (1996) Potent modulation of neuronal nicotinic acetylcholine receptor channel by ethanol. Neurosci. Lett. 217, 189-193.
41. Nordberg A. and Wahlström G. (1992) Cholinergic mechanisms in physical dependence on barbiturates, ethanol and benzodiazepines. J. Neural Transm. 88, 199-221.
42. Nordberg A., Wahlström G., and Eriksson B. (1986) Relation between muscimol, quinuclidinyl benzilate and nicotine binding sites in brain after long-term treatment. Acta Physiol. Scand. 126, 153-156.
43. Overstreet D. H. (1995) Differential effect of nicotine in inbred and selectively bred rodents. Behav. Genet. 25, 179-185.
44. Peng X., Gerzanich V., Anand R., Whiting P. J., and Lindstrom J. (1994) Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover. Mol. Pharmacol. 46, 523-530.
45. Peng X., Gerzanich V., Anand R., Wang F., and Lindstrom J. (1997) Chronic nicotine treatment up-regulates α3 and α7 acetylcholine receptor subtypes expressed by the human neuroblastoma cell line SH-SY5Y. Mol. Pharmacol. 51, 776-784.
46. Rodriguez F. D., Simonsson P., and Alling C. (1992) A method for maintaining constant ethanol concentrations in cell culture media. Alcohol Alcohol. 27, 309-313.
47. Rubboli F., Court J. A., Sala C., Morris C., Chini B., Perry E., and Clementi F. (1994) Distribution of nicotinic receptors in human hippocampus and thalamus. Neurochem. Int. 25, 69-71.
48. Saito H., Nishida A., Shimizu M., Motohashi N., and Yamawaki S. (1996) Effects of chronic ethanol treatment on inositol 1,4,5-trisphosphate receptors and inositol 1,3,4,5-tetrakisphosphate receptors in rat brain. Neuropsychobiology 33, 60-65.
49. Singh S. P., Ehmann S., and Snyder A. K. (1996) Ethanol-induced changes in insulin-like growth factors and IGF gene expression in the fetal brain. Proc. Soc. Exp. Biol. Med. 212, 349-354.
50. Tonner P. H., Wood S. C., and Miller K. W. (1992) Can nicotine self-inhibition account for its low efficacy at the nicotinic acetylcholine receptor from Torpedo? Mol. Pharmacol. 42, 890-897.
51. Whiting P. J., Schoepfer R., Lindstrom J., and Priestley T. (1991) Structural and pharmacological characterization of the major brain nicotinic acetylcholine subtype stably expressed in mouse fibroblasts. Mol. Pharmacol. 40, 463-472.
52. Wonnacott S. (1990) The paradox of nicotinic acetylcholine receptor upregulation by nicotine. Trends Pharmacol. Sci. 11, 216-219.
53. Wood S. C., Tonner P. H., deArmendi A. J., Bugge B., and Miller K. W. (1995) Channel inhibition by alkanols occurs at a binding site on the nicotinic acetylcholine receptor. Mol. Pharmacol. 47, 121-130.
54. Wu G. and Miller K. W. (1994) Ethanol enhances agonist-induced fast desensitization in nicotinic acetylcholine receptor. Biochemistry 33, 9085-9091.
55. Wu G., Tonner P. H., and Miller K. W. (1994) Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor. Mol. Pharmacol. 45, 102-108.
56. Yoshida K., Engel J., and Liljequist S. (1982) The effect of chronic ethanol administration on high affinity [3H] nicotine binding in rat brain. Naunyn Schmiedebergs Arch. Pharmacol. 321, 74-76.
57. Yu D., Zhang L., Eisele J.-L., Bertrand D., Changeux J.-P., and Weight F. F. (1996) Ethanol inhibition of nicotinic acetylcholine type α7 receptor involves the amino-terminal domain of the receptor. Mol. Pharmacol. 50, 1010-1016.
58. Zhang X. and Nordberg A. (1995) Characterization of nicotinic acetylcholine receptors in brain, in Imaging of Nicotine and Tobacco Smoking (Domino E. F., ed), pp. 59-71. NPP Books, Ann Arbor.
59. Zhang X., Gong Z. H., Hellström-Lindahl E., and Nordberg A. (1995) Regulation of α4β2 nicotinic acetylcholine receptors in M10 cells following treatment with nicotinic agents. Neuroreport 6, 313-317.