Ethanol exposure reduces the density of the low-affinity nerve growth factor receptor (p75) on pheochromocytoma (PC12) cells

Brain Research

Volumn 737, Issue 1-2, 1996, Pages 34-44

  Luo, Jia ^a   West, James R ^b   Pantazis, Nicholas J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

Cell culture; Fetal alcohol syndrome; Immunoprecipitation; Nerve growth factor binding study; Nerve growth factor receptor; Neurotrophin; Northern blot analysis; PC12

Indexed keywords

ALCOHOL; MESSENGER RNA; NERVE GROWTH FACTOR RECEPTOR;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; FETAL ALCOHOL SYNDROME; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

EID: 0030597190     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00657-9     Document Type: Article

References (77)

1. [1] Abel, E.L. and Sokol, R.J., Incidence of fetal alcohol syndrome and economic impact of FAS-related anomalies, Drug Alcohol Depend., 19 (1987) 51-70.
2. [2] Aloe, L., Bracci-Laudiero, L. and Tirassa, P., The effect of chronic ethanol intake on brain NGF level and on NGF-target tissues of adult mice, Drug Alcohol Depend., 31 (1993) 159-167.
3. [3] Aloe, L. and Tirassa, P., The effect of long-term alcohol intake on brain NGF-target cells of aged rats, Alcohol, 9 (1992) 299-304.
4. [4] Assouline, J.G. and Pantazis, N.J., Detection of a nerve growth factor receptor on fetal human Schwann cells in culture: absence of the receptor on fetal human astrocytes, Dev. Brain Res., 45 (1989) 1-14.
5. [5] Baek, J.K., Heaton, M.B. and Walker, D.W., Chronic alcohol ingestion: nerve growth factor gene expression and neurotrophic activity in rat hippocampus, Alcohol Clin. Exp. Res., 18 (1994) 1368-1376.
6. [6] Barbacid, M., Nerve growth factor; a tale of two receptors, Oncogene, 8 (1993) 2033-2042.
7. [7] Barker, P. and Shooter, E.M., Disruption of NGF binding to the low affinity neurotrophin receptor p75 reduced NGF binding to trkA on PC12 cells, Neuron, 13 (1994) 203-215.
8. [8] Barrett, G.L. and Bartlett, P.F., The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development, Proc. Natl. Acad. Sci. USA, 91 (1994) 6501-6505.
9. [9] Battleman, D.S., Geller, A.I. and Chao, M.V., HSV-1 vector mediated gene transfer of the human nerve growth factor receptor p75 defines high affinity NGF binding, J. Neurosci., 13 (1993) 941-951.
10. [10] Benedetti, M., Levi, A. and Chao, M.V., Differential expression of nerve growth factor receptor leads to altered binding affinity and neurotrophin responsiveness, Proc. Natl. Acad. Sci. USA, 90 (1993) 7859-7863.
11. [11] Berg, M.M., Sternberg, D.W., Hempstead, B.L. and Chao, M.V., The low affinity nerve growth factor (NGF) receptor mediates NGF-induced tyrosine phosphorylation, Proc. Natl. Acad. Sci. USA, 88 (1991) 7106-7110.
12. [12] Bothwell, M., Functional interactions of neurotrophins and neurotrophin receptors, Annu. Rev. Neurosci., 18 (1995) 223-253.
13. [13] Bradshaw, R.A., Blundell, T.L., Lapatto, R., McDonald, N.Q. and Murray-Rust, J., Nerve growth factor revisited, Trends Biochem. Sci., 18 (1993) 48-52.
14. [14] Buck, C.R., Martinez, H.J., Chao, M.V. and Black, I.B., Differential expression of the nerve growth factor receptor gene in multiple brain areas, Dev. Brain Res., 44 (1988) 259-268.
15. [15] Chao, M.V., Neurotrophin receptor: a window into neuronal differentiation, Neuron, 9 (1992) 583-593.
16. [16] Chao, M.V. and Hempstead, B.L., p75 and Trk: a two-receptor system, Trends Neurosci., 18 (1995) 321-326.
17. [17] Dalke, D.D., Sorrell, M.F., Casey, C.A. and Tuma, D.J., Chronic ethanol administration impairs receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes, Hepatology, 12 (1990) 1085-1091.
18. [18] Davies, D.L. and Smith, D.E., A Golgi study of mouse hippocampal CA1 pyramidal neurons following perinatal ethanol exposure, Neurosci. Lett., 26 (1981) 49-54.
19. [19] Dohrman, D.P., West, J.R. and Pantazis, N.J., Ethanol reduces expression of the nerve growth factor receptor but not NGF protein levels in the neonatal rat cerebellum, Submitted (1996).
20. [20] Dow, K.E. and Riopelle, R.J., Ethanol neurotoxicity: Effects on neurite formation and neurotrophic factor production in vitro, Science, 228 (1985) 591-593.
21. [21] Goodlett, C.R., Mahoney, J.C. and West, J.R., Brain growth deficits following a single day of alcohol exposure in neonatal rat, Alcohol, 6 (1989) 121-126.
22. [22] Goodlett, C.R., Marcussen, B.L. and West, J.R., A single day of alcohol exposure during the brain growth spurt induces brain weight restriction and cerebellar Purkinje cell loss, Alcohol, 7 (1990) 107-114.
23. [23] Gottesfeld, Z., Morgan, B. and Perez-Polo, J.R., Prenatal alcohol exposure alters the development of sympathetic synaptic components and of nerve growth factor receptor expression selectivity in lymphoid organs, J. Neurosci. Res., 26 (1990) 308-316.
24. [24] Greene, L.A. and Tischler, A.S., Establishment of noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor, Proc. Natl. Acad. Sci. USA, 73 (1976) 2424-2428.
25. [25] Green, S.H., Ryoel, R.E., Connolly, J.L. and Greene, L.A., PC12 mutants that possess low-not high-affinity nerve growth factor receptor neither respond to nor internalize nerve growth factor, J. Cell Biol., 102 (1986) 830-843.
26. [26] Hagg, T., Rende, M., Magal, E., Burnham, P., Oudega, M. and Varon, S., Potential regulation by trophic factors of low-affinity NGF receptors in spinal motor neurons, Brain Res. Bull., 30 (1993) 347-352.
27. [27] Heaton, M.B., Swanson, D.J., Pavia, M. and Walker, D.W., Ethanol exposure affects trophic factor activity and responsiveness in chick embryo, Alcohol, 9 (1992) 161-166.
28. [28] Heaton, M.B., Paiva, M., Swanson, D.J. and Walker, D.W., Modulation of ethanol neurotoxicity by nerve growth factor, Brain Res., 620 (1993) 78-85.
29. [29] Heaton, M.B., Paiva, M., Swanson, D.J. and Walker, D.W., Alterations in responsiveness to ethanol and neurotrophic substances in fetal septohippocampal neurons following chronic prenatal ethanol exposure, Dev. Brain Res., 85 (1995) 1-13.
30. [30] Hempstead, B.L., Patil, N., Thiel, B. and Chao, M.V., Deletion of cytoplasmic sequences of the nerve growth factor receptor leads to loss of high affinity ligand binding, J. Biol. Chem., 265 (1990) 9595-9598.
31. [31] Hempstead, B.L., Martin-Zanca, D., Kaplan, D.R., Parada, L.F. and Chao, M.V., High-affinity NGF binding requires co-expression of the trk proto-oncogene and low affinity NGF receptor, Nature, 350 (1991) 678-682.
32. [32] Huber, L.J. and Chao, M.V., A potential interaction of p75 and trk A NGF receptors revealed by affinity crossing and immunoprecipitation, J. Neurosci. Res., 40 (1995) 557-563.
33. [33] Hunter, W.H. and Greenwood, F.C., Preparation of iodine-131 labeled human growth hormone of high specific activity, Nature, 194 (1962) 495-496.
34. [34] Jing, S., Tapley, P. and Barbacid, M., Nerve growth factor mediates signal transduction through trk homodimer receptors, Neuron. 9 (1992) 1067-1079.
35. [35] Johnson, E.M., Taniuchi, M., Clark, H.B., Springer, J.E., Koh, S., Tayrien, M.W. and Loy, R., Demonstration of the retrograde transport of NGF receptor in the peripheral and central nervous system, J. Neurosci., 7 (1987) 923-929.
36. [36] Kaplan, D.R., Martin-Zanca, D. and Parada, L.F., Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF, Nature, 350 (1991) 158-160.
37. [37] Kaplan, D.R., Hempstead, B.L., Martin-Zanca, D., Chao, M.V. and Parada, L.F., The trk proto-oncogene product: a signal transducing receptor for nerve growth factor, Science, 252 (1991) 554-557.
38. [38] Klein, R., Jing, S.Q., Nanduri, V., O'Rourke, E. and Barbacid, M., The trk proto-oncogene encodes a receptor for nerve growth factor, Cell, 65 (1991) 189-197.
39. [39] Korsching, S., The neurotrophic factor concept: a re-examination, J. Neurosci., 13 (1993) 2739-2748.
40. [40] Laemmli, U.K., Cleavage of structural proteins during assembly of the head of bacteriophage T4, Nature, 227 (1970) 680-685.
41. [41] Landreth, G.E. and Shooter, E.M., Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low-to high-affinity states, Proc. Natl. Acad. Sci. USA, 77 (1980) 4751-4755.
42. 125I-labeled glucagon binding as a metabolic probe, Can. J. Physiol. Pharmacol., 60 (1982) 1171-1176.
43. [43] Lee, K.-F., Davies, A.M. and Jaenisch, R., p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF, Development, 120 (1994) 1027-1033.
44. [44] Leonard, B.E., Ethanol as a neurotoxin, Biochem. Pharmacol., 36 (1987) 2055-2059.
45. [45] Levi-Montalcini, R., The nerve growth factor thirty-five years later, In Vitro Cell Dev. Biol., 23 (1987) 227-238.
46. [46] Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurement with the folin phenol reagent. J. Biol. Chem., 193 (1951) 265-273.
47. [47] Luo, J., West, J.R. and Pantazis, N.J., Growth factor-mediated neuroprotection against ethanol-induced death of cerebellar granule cells, Manuscript in preparation.
48. 140trk binding: implications for multi-subunit polypetide receptors, J. Biol. Chem., 269 (1994) 6884-6891.
49. [49] Majewska, M.D., Interaction of ethanol with the GABA receptor in the rat brain: possible involvement of endogenous steroids, Alcohol, 5 (1988) 269-273.
50. [50] Meakin, S.O. and Shooter, E.M., The nerve growth factor family of receptors, Trends Neurosci., 15 (1992) 323-331.
51. [51] Messing, R.O., Henteleff, M. and Park, J.J., Ethanol enhances growth factor-induced neurite formation in PC12 cells, Brain Res., 565 (1991) 301-311.
52. [52] Miller, M.W., Effects of alcohol on the generation and migration of cerebral cortical neurons, Science, 233 (1986) 1308-1311.
53. [53] Miller, M.W. and Potempa, G., Numbers of neurons and glia in mature rat somatosensory cortex: effects of prenatal exposure to ethanol, J. Comp. Neurol., 293 (1990) 92-102.
54. [54] Muller, Y., Duperray, C., Caruso, F. and Clos, J., Autocrine regulation of proliferation of cerebellar granule neurons by nerve growth factor, J. Neurosci. Res., 38 (1994) 41-55.
55. [55] Pantazis, N.J., Dohrman, D.P., Luo, J., Goodlett, C.R. and West, J.R., Alcohol reduces the number of pheochromcytoma (PC12) cells in culture, Alcohol, 9 (1992) 171-180.
56. [56] Pantazis, N.J., Luo, J. and West, J.R., Growth factor-mediated neuroprotection against alcohol-induced death of cerebellar granule cells, Abstract, Annual Meeting Research Society on Alcoholism, 1994.
57. [57] Puissant, C. and Houdebine, L.M., An improvement of the single step method of RNA isolation by acid guidinium thiocyanate-phenol-chloroform extraction, Biotechniques, 8 (1990) 148.
58. [58] Rabizadeh, S., Oh, J., Zhong, L.-T., Yang, J., Bitler, C.M., Butcher, L.L. and Bredesen, D.E., Induction of apoptosis by the low-affinity NGF receptor, Science, 261 (1993) 345-348.
59. [59] Rahman, H., Kentroti, S. and Vernadakis, A., Early in vivo exposure of chick embryos to ethanol prevents the neuronotrophic effects of intracerebral NGF administration of cholinergic phenotypic expression, Dev. Brain Res., 76 (1993) 256-259.
60. [60] Rifkin, R.M., Todd, W.W., Toothaber, D.R., Sussman, A., Trowbridge, M. and Drazninm B., Effects of in vivo and in vitro alcohol administration on insulin binding and glycogenesis for isolated rat hepatocytes, Ann. Neurol. Metab., 27 (1983) 313-319.
61. [61] Roivainen, R., McMahon, T. and Messing, R.O., Protein kinase C isozymes that mediate enhancement of neurite outgrowth by ethanol and phorbol esters in PC12 cells, Brain Res., 624 (1993) 85-93.
62. [62] Roivainen, R., Hundle, B. and Messing, R.O., Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism, Proc. Natl. Acad. Sci. USA, 92 (1995) 1891-1895.
63. [63] Rosenthal, H., Graphic method for the determination and presentation of binding parameters in a complex system, Anal. Biochem., 20 (1967) 525-532.
64. [64] Rovinski, B., Hosein, E.A. and Lee, H., Effect of maternal ethanol ingestion during pregnancy and lactation on the structure and function of the postnatal rat liver plasma membrane, Biochem. Pharmacol., 33 (1984) 311-317.
65. [65] Scatchard, G., The attractions of proteins for small molecules and ions, Ann. NY Acad. Sci., 51 (1949) 660-672.
66. [66] Scheibe, R.J. and Wagner, J.A., Retinoic acid regulates both expression of the nerve growth factor receptor and sensitivity to nerve growth factor, J. Biol. Chem., 267 (1992) 17611-17616.
67. [67] Taniuchi, M., Schweitzer, J.B. and Johnson, Jr. E.M., Nerve growth factor receptor molecules in rat brain, Proc. Natl. Acad. Sci. USA, 83 (1986) 1950-1954.
68. [68] Taniuchi, M., Clark, H.B., Schweitzer, J.B. and Johnson, E.M., Expression of nerve growth factor receptor by Schwann cells of axotomized peripheral nerves: ultrastructure location, suppression by axonal contact, and binding properties, J. Neurosci., 8 (1988) 664-681.
69. [69] Tuma, D.J., Maillard, M.E., Casey, C.A. and Volentine, G.D., Ethanol-induced alteration of plasma membrane assembly in the liver, Biochim. Biophys. Acta, 856 (1986) 571-577.
70. [70] Vale, R.D. and Shooter, E.M., Assaying binding of nerve growth factor to cell surface receptors, Methods Enzymol., 109 (1985) 21-39.
71. [71] Valles, S., Lindo, L., Montoliu, C., Renau-Piqueras, J. and Guerri, C., Prenatal exposure to ethanol induces changes in the nerve growth factor and its receptor in proliferating astrocytes in primary culture, Brain Res., 656 (1994) 281-286.
72. [72] Verdi, J., Birren, S., Ibanez, C., Benedetti, M., Chao, M.V. and Anderson, D., p75 regulates trk signal transduction and NGF-induced neuronal differentiation in MAH cells, Neuron, 12 (1994) 733-745.
73. [73] West, J.R., Chen, W.-J.A. and Pantazis, N.J., Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage, Metab. Brain Dis., 9 (1994) 291-322.
74. [74] West, J.R., Goodlett, C.R., Bonthius, D.J., Hamre, K.M. and Marcussen, B.L., Cell population depletion associated with fetal alcohol brain damage: mechanism of BAC-dependent cell loss, Alcohol Clin. Exp. Res., 14 (1990) 813-818.
75. [75] West, J.R., Hodges, C.A. and Black, A.C., Jr., Prenatal exposure to alcohol alters the organization of hippocampal mossy fibers in rats, Science, 211 (1981) 957-959.
76. [76] Wooten, M.W. and Ewald, S.J., Alcohols synergize with NGF to induce early differentiation of PC12 cells, Brain Res., 550 (1991) 333-339.
77. [77] Xu, H., Federoff, H., Maragos, J., Parada, L.F. and Kessler, J.A., Viral transduction of trkA into cultured nodose and spinal motor neurons conveys NGF responsiveness, Dev. Biol., 163 (1994) 152-161.