Long-term exposure to ethanol increases the number and function of muscarinic M1 receptors in human neuroblastoma cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 1, 1996, Pages 313-319

  Larsson, Christer ^a,b   Simonsson, Per ^a   Caron, Murielle ^a   Alling, Christer ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CARBACHOL; INOSITOL; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL TRISPHOSPHATE; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; PIRENZEPINE; QUINUCLIDINYL BENZILATE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; RECEPTOR DENSITY;

CARBACHOL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HUMANS; NEUROBLASTOMA; RECEPTORS, MUSCARINIC;

EID: 0030434273     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. BABTLETT, G. R.: Phosphorus assay in column chromatography. J. Biol. Chem. 234: 466-468, 1959.
2. BRADFORD, M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254, 1976.
3. BREDT, D. S., MOUREY, R. J. AND SNYDER, S. H.: A. simple, sensitive and specific radioreceptor assay for inositol 1,4,5-trisphosphate in biological tissue. Biochem. Biophys. Res. Commun. 159: 976-982, 1989.
4. BUCK, K. J. AND HARRIS, R. A.: Neuroadaptive responses to chronic ethanol. Alcohol. Clin. Exp. Res. 15: 460-470, 1991.
5. FOWLER, C. J., O'NEILL, C., AIMQVIST, P., NILSSON, S., WIEHAGER, B. AND WINBLAD, B.: Muscarinic receptors coupled to inoeitol phospholipid breakdown in human SH-SY5Y neuroblastoma cells: effect of retinoic acid differentiation. Neurochem. Int. 15: 73-79, 1989.
6. GONZALES, R. A. AND CREWS, F. T.: Effects of ethanol in vivo and in vitro on stimulated pbosphoinositide hydrolysis in rat cortex and cerebellum. Alcohol. Clin. Exp. Res. 12: 94-98, 1988.
7. HOEK, J. B. AND RUBIN, E.: Alcohol and membrane-associated signal transduction. Alcohol Alcohol. 25: 143-156, 1990.
8. HOFFMAN, P. L., MOSES, F., LUTHIN, G. R. AND TABAKOFF, B.: Acute and chronic effects of ethanol on receptor-mediated phoephatidylinositol 4,5-bisphoshate breakdown in mouse brain. Mol. Pharmacol. 30: 13-18, 1986.
9. HUNT, W. A. AND DALTON, T. K.: Neurotransmitter-receptor binding in various brain regions in ethanol-dependent-rats. Pharmacol. Biochem. Behav. 14: 733-739, 1981.
10. KENNERLY, D. A.: Diacylglycerol metabolism in mast cells. J. Biol. Chem. 262: 16305-16313, 1987.
11. ++ mobilization and northern blotting. J. Pharmacol. Exp. Ther. 263: 1487-1493, 1992.
12. KURIYAMA, K. AND OHKUMA, S.: Alteration in the function of cerebral neurotrans-mitter receptors during the establishment of alcohol dependence: Neurochemical aspects. Alcohol Alcohol. 25: 239-249, 1990.
13. 2+ and inositol 1,4,5-trisphosphate mass in a human neuroblastoma cell line, SH-SY5Y. Biochem. J. 265: 555-562, 1990.
14. LARSSON, C., GUSTAVSSON, L., SIMONSSON, P., BERGMAN, O. AND ALLING, C.: Mechanisms of muscarinic receptor-stimulated c-fos expression in SH-SY5Y cells. Eur. J. Pharmacol. 268: 19-28, 1994.
15. LARSSON, C., SIMONSSON, P., HOEK, J. B. AND ALLING, C.: Ethanol inhibits the peak of muscarinic receptor-stimulated formation of inositol 1,4,5-trisphosphate in neuroblastoma SH-SY5Y cells. Biochem. Pharmacol. 60: 647-654, 1995.
16. MULLER, P., BRITTON, R. S. AND SEEMAN, P.: The effects of long-term ethanol on brain receptors for dopamine, acetylcholine, serotonin and noradrenaline. Eur. J. Pharmacol. 65: 31-37, 1980.
17. PIETRZAK, E. R., WILCE, P. A. AND SHANLEY, B. C.: Interaction of chronic ethanol consumption and aging on brain muscarinic cholinergic receptors. J. Pharmacol. Exp. Ther. 252: 869-874, 1990.
18. RODRIGUEZ, F. D., SIMONSSON, P. AND ALLING, C.: A method for maintaining constant ethanol concentrations in cell culture media. Alcohol Alcohol. 27: 309-313, 1992.
19. SADÉE, W., YU, V. C., RICHARDS, M. L., PREIS, P. N., SCHWAB, M. R., BRODSKY, F. M. AND BIEDLER, J. L.: Expression of neurotransmitter receptors and myc protooncogenes in subclones of a human neuroblastoma cell line. Cancer Res. 47: 5207-5212, 1987.
20. 3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols. J. Neurochem. 50: 1513-1521, 1988.
21. SIMONSSON, P., HANSSON, E. AND ALLING, C.: Ethanol potentiates serotonin stimulated inositol lipid metabolism in primary astroglial cell cultures. Biochem. Pharmacol. 38: 2801-2805, 1989a.
22. SIMONSSON, P., SUN, G. Y., VECSEI, L. AND ALLING, C.: Ethanol effects on bradykinin-stimulated phosphoinositide hydrolysis in NG 108-15 neuroblastomaglioma cells. Alcohol 6: 475-479, 1989b.
23. SIMONSSON, P. AND ALLING, C.: The 5-hydroxytryptamine stimulated formation of inositol phosphate is inhibited in platelets from alcoholics. Life Sci. 42: 385-391, 1988.
24. SMITH, T. L.: Selective effects of acute and chronic ethanol exposure on neuropeptide and guanine nucleotide stimulated phospholipase C activity in intact N1E-115 neuroblastoma. J. Pharmacol. Exp. Ther. 258: 410-415, 1991.
25. STEEL, M. C. AND BUCKLEY, N. J.: Differential regulation of muscarinic receptor mRNA levels in neuroblastoma cells by chronic agonist exposure: a comparative polymerase chain reaction study. Mol. Pharmacol. 43: 694-701, 1993.
26. UEDA, N., INIGUEZ-LLUHI, J. A., LEE, E., SMBCKA, A. V., ROBISHAW, J. D. AND GILMAN, A. G.: G. protein βy subunits. Simplified purification and properties of novel isoforms. J. Biol. Chem. 269: 4388-4395, 1994.
27. WALL, S. J., YASUDA, R. P., LI, M. AND WOLFE, B. B.: Development of an antiserum against m3 muscarinic receptors: Distribution of m3 receptors in rat tissue and clonal cell lines. Mol. Pharmacol. 40: 783-789, 1991.