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Volumn 9, Issue 2, 1998, Pages 125-154

Interferon-α-n1. A review of its pharmacological properties and therapeutic efficacy in the management of chronic viral hepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHAN1 INTERFERON; ANTIVIRUS AGENT; CORTICOSTEROID; DEFLAZACORT; HEPATITIS B(E) ANTIGEN; LEVAMISOLE; NEUTRALIZING ANTIBODY; PARACETAMOL; PREDNISOLONE; PREDNISONE; RECOMBINANT ALPHA INTERFERON; VIRUS DNA; ZIDOVUDINE;

EID: 0031913056     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-199809020-00004     Document Type: Review
Times cited : (12)

References (144)
  • 1
    • 0028814072 scopus 로고
    • Major therapeutic uses of interferons
    • Cirelli R, Tyring SK. Major therapeutic uses of interferons. Clin Imminother 1995; 3(1): 27-87
    • (1995) Clin Imminother , vol.3 , Issue.1 , pp. 27-87
    • Cirelli, R.1    Tyring, S.K.2
  • 2
    • 0027222630 scopus 로고
    • Biological basis for the clinical use of interferon
    • Dianzani F. Biological basis for the clinical use of interferon. Gut 1993: S74-6
    • (1993) Gut
    • Dianzani, F.1
  • 3
    • 0030931158 scopus 로고    scopus 로고
    • Therapy of hepatitis C: Interferon alfa-nl trials
    • Farrell GC. Therapy of hepatitis C: Interferon alfa-nl trials. Hepatology 1997; 26 Suppl. 1: 96S-100S
    • (1997) Hepatology , vol.26 , Issue.1 SUPPL.
    • Farrell, G.C.1
  • 4
    • 0027471685 scopus 로고
    • Interferon-α in malignant and viral diseases: A review
    • Dorr RT. Interferon-α in malignant and viral diseases: a review. Drugs 1993; 45 (2): 177-211
    • (1993) Drugs , vol.45 , Issue.2 , pp. 177-211
    • Dorr, R.T.1
  • 6
    • 0027939325 scopus 로고
    • Inhibition of hepatitis B virus in tissue culture by alpha interteron
    • Dec
    • Davis MG, Jansen RW. Inhibition of hepatitis B virus in tissue culture by alpha interteron. Antimicrob Agents Chemother 1994 Dec; 38: 2921-4
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 2921-2924
    • Davis, M.G.1    Jansen, R.W.2
  • 7
    • 0025138795 scopus 로고
    • Interferon-induced proteins and the antiviral state
    • Staehcli P. Interferon-induced proteins and the antiviral state. Adv Virus Res 1990; 38: 147-200
    • (1990) Adv Virus Res , vol.38 , pp. 147-200
    • Staehcli, P.1
  • 8
    • 0023762894 scopus 로고
    • Differential effect of α-interferons on CD4- and CD8-positive lymphocytes in chronic hepatitis B virus carriers
    • Nouri-Aria KT, Alexander GJM, Magrin S, et al. Differential effect of α-interferons on CD4- and CD8-positive lymphocytes in chronic hepatitis B virus carriers. J Hepatol 1988; 7 (1): 1-6
    • (1988) J Hepatol , vol.7 , Issue.1 , pp. 1-6
    • Nouri-Aria, K.T.1    Alexander, G.J.M.2    Magrin, S.3
  • 9
    • 6844243742 scopus 로고
    • Changes in peripheral blood lymphocyte subsets in chronic hepatitis C: Differences between α-2b and α-nl interferon
    • Oct
    • Lucas M, Serejo F, Valente A, et al. Changes in peripheral blood lymphocyte subsets in chronic hepatitis C: differences between α-2b and α-nl interferon [abstract]. Hepatology 1993 Oct; 18(Pt 2): 241A
    • (1993) Hepatology , vol.18 , Issue.2 PART
    • Lucas, M.1    Serejo, F.2    Valente, A.3
  • 10
    • 0027473444 scopus 로고
    • Lymphoblastoid α-interferon for chronic hepatitis C: A randomized controlled study
    • Custilla A, Camps Bansell-J, Civeira M-P, et al. Lymphoblastoid α-interferon for chronic hepatitis C: a randomized controlled study. Am J Gastroenterol 1993; 88 (2): 233-9
    • (1993) Am J Gastroenterol , vol.88 , Issue.2 , pp. 233-239
    • Custilla, A.1    Bansell-J, C.2    Civeira, M.-P.3
  • 11
    • 0022486999 scopus 로고
    • Human lymphoblastoid interferon. In vitro and in vivo studies in hepatocellular carcinoma
    • Dunk AA, Ikeda T, Pignatelli M, et al. Human lymphoblastoid interferon. In vitro and in vivo studies in hepatocellular carcinoma. J Hepatol 1986; 2 (3): 419-29
    • (1986) J Hepatol , vol.2 , Issue.3 , pp. 419-429
    • Dunk, A.A.1    Ikeda, T.2    Pignatelli, M.3
  • 12
    • 0023621548 scopus 로고
    • Natural killer cell activity in hepatocellular carcinoma. In vitro and in vivo responses to interferon
    • Dunk AA, Novick D, Thomas HC. Natural killer cell activity in hepatocellular carcinoma. In vitro and in vivo responses to interferon. Scand J Gastroenterol 1987; 22 (10): 1245-50
    • (1987) Scand J Gastroenterol , vol.22 , Issue.10 , pp. 1245-1250
    • Dunk, A.A.1    Novick, D.2    Thomas, H.C.3
  • 13
    • 0027386134 scopus 로고
    • Interferon-α increases prostaglandin E2 production by cultured liver biopsy in patients with chronic viral hepatitis: Can non-steroidal anti-inflammatory drugs improve the therapeutic response to interferon?
    • Andreone P, Cursaro C, Gasbarrini G. Interferon-α increases prostaglandin E2 production by cultured liver biopsy in patients with chronic viral hepatitis: can non-steroidal anti-inflammatory drugs improve the therapeutic response to interferon? J Hepatol 1993; 19(2): 228-31
    • (1993) J Hepatol , vol.19 , Issue.2 , pp. 228-231
    • Andreone, P.1    Cursaro, C.2    Gasbarrini, G.3
  • 14
    • 0025841652 scopus 로고
    • Effects of human lymphoblastoid interferon on proliferation, gene expression and tumourigenicity of human hepatoma cell lines
    • Huber BE, Wirth PJ, Newbold JE. Effects of human lymphoblastoid interferon on proliferation, gene expression and tumourigenicity of human hepatoma cell lines. Drugs Exp Clin Res 1991; 17: 281-91
    • (1991) Drugs Exp Clin Res , vol.17 , pp. 281-291
    • Huber, B.E.1    Wirth, P.J.2    Newbold, J.E.3
  • 15
    • 6844219755 scopus 로고
    • Induction of neutralizing antibodies to interferon during treatment of hepatitis patients: Comparison among different interferon preparations
    • Apr
    • Dianzani F, Antonelli G, Currenti M, et al. Induction of neutralizing antibodies to interferon during treatment of hepatitis patients: comparison among different interferon preparations [abstract]. Antiviral Res 1991 Apr; 15 Suppl. 1: 127
    • (1991) Antiviral Res , vol.15 , Issue.1 SUPPL. , pp. 127
    • Dianzani, F.1    Antonelli, G.2    Currenti, M.3
  • 16
    • 0028168059 scopus 로고
    • Specificities of therapy-induced antiinterferon-α antibodies
    • Aug
    • Brand CM, Leadbeater L. Specificities of therapy-induced antiinterferon-α antibodies. J Interferon Res 1994 Aug; 14: 201-3
    • (1994) J Interferon Res , vol.14 , pp. 201-203
    • Brand, C.M.1    Leadbeater, L.2
  • 17
    • 0025759062 scopus 로고
    • Neutralizing antibodies to interferon-α: Relative frequency in patients treated with different interferon preparations
    • Apr
    • Antonelli G, Currenti M, Turriziani O, et al. Neutralizing antibodies to interferon-α: relative frequency in patients treated with different interferon preparations. J Infect Dis 1991 Apr; 163: 882-5
    • (1991) J Infect Dis , vol.163 , pp. 882-885
    • Antonelli, G.1    Currenti, M.2    Turriziani, O.3
  • 18
    • 0027412933 scopus 로고
    • Antibodies developing against a single recombinant interferon protein may neutralize many other interferon-α subtypes
    • Apr
    • Brand CM, Leadbeater L, Bellati G, et al. Antibodies developing against a single recombinant interferon protein may neutralize many other interferon-α subtypes. J Interferon Res 1993 Apr; 13: 121-5
    • (1993) J Interferon Res , vol.13 , pp. 121-125
    • Brand, C.M.1    Leadbeater, L.2    Bellati, G.3
  • 20
    • 0024225347 scopus 로고
    • Mechanisms of the antiviral action of the interferons
    • Samuel CE. Mechanisms of the antiviral action of the interferons. Prog Nucleic Acid Res Mol Biol 1988; 35: 27-72
    • (1988) Prog Nucleic Acid Res Mol Biol , vol.35 , pp. 27-72
    • Samuel, C.E.1
  • 21
    • 0026701148 scopus 로고
    • Type 1 interferons inhibit hepatitis B virus replication and induce hepatocellular gene expression in cultured liver cels
    • Caselmann WH, Meyer M, Scholz S, et al. Type 1 interferons inhibit hepatitis B virus replication and induce hepatocellular gene expression in cultured liver cels. J Infect Dis 1992; 166: 966-71
    • (1992) J Infect Dis , vol.166 , pp. 966-971
    • Caselmann, W.H.1    Meyer, M.2    Scholz, S.3
  • 22
    • 0025739093 scopus 로고
    • Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • Samuel CE. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 1991; 183: 1-11
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 23
    • 0025972316 scopus 로고
    • An intracellular 50-kDa Fcγ-binding protein is induced in human cells by α-IFN
    • Thomas NSB, Linch DC. An intracellular 50-kDa Fcγ-binding protein is induced in human cells by α-IFN. J Immunol 1991 ; 146(5): 1649-54
    • (1991) J Immunol , vol.146 , Issue.5 , pp. 1649-1654
    • Thomas, N.S.B.1    Linch, D.C.2
  • 24
    • 0026027850 scopus 로고
    • Signal transduction by interferon-α through arachidonic metabolism
    • Hannigan GE, Williams BRG. Signal transduction by interferon-α through arachidonic metabolism. Science 1991; 251: 204-7
    • (1991) Science , vol.251 , pp. 204-207
    • Hannigan, G.E.1    Williams, B.R.G.2
  • 25
    • 0028030685 scopus 로고
    • Indomethacin increases 2',5'-oligoadenylate synthetase release by cultured liver tissue of patients with HCV chronic active hepatitis
    • Andreone P, Cursaro C, Gramenzi A, et al. Indomethacin increases 2',5'-oligoadenylate synthetase release by cultured liver tissue of patients with HCV chronic active hepatitis. Int Hepatol Commun 1994; 2(5): 289-94
    • (1994) Int Hepatol Commun , vol.2 , Issue.5 , pp. 289-294
    • Andreone, P.1    Cursaro, C.2    Gramenzi, A.3
  • 26
    • 0019311009 scopus 로고
    • Integration of hepatitis B virus sequences and their expression in a human hepatoma cell
    • Jul 31
    • Edman JC, Gray P, Vulenzuela P, et al. Integration of hepatitis B virus sequences and their expression in a human hepatoma cell. Nature 1980 Jul 31; 286: 535-8
    • (1980) Nature , vol.286 , pp. 535-538
    • Edman, J.C.1    Gray, P.2    Vulenzuela, P.3
  • 27
    • 0022629798 scopus 로고
    • The relation between hepatitis B virus infection and hepatocellular carcinoma
    • Popper H. The relation between hepatitis B virus infection and hepatocellular carcinoma. Hepatogastroenterology 1986; 33: 2-5
    • (1986) Hepatogastroenterology , vol.33 , pp. 2-5
    • Popper, H.1
  • 28
    • 0026551624 scopus 로고
    • The role of hepatitis B and C viruses in hepatocellular carcinoma in a hepatitis B endemic area. A case-control study
    • Chuang W-L. Chang W-Y. Lu S-N. et al. The role of hepatitis B and C viruses in hepatocellular carcinoma in a hepatitis B endemic area. A case-control study. Cancer 1992; 69: 2052-4
    • (1992) Cancer , vol.69 , pp. 2052-2054
    • Chuang, W.-L.1    Chang, W.-Y.2    Lu, S.-N.3
  • 29
    • 0024450697 scopus 로고
    • Prevalence of antibody to hepatitis C virus in Italian patients with hepatocellular carcinoma
    • Colombo M, Choo QL, Del Ninno E. et al. Prevalence of antibody to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989; II: 1006-8
    • (1989) Lancet , vol.2 , pp. 1006-1008
    • Colombo, M.1    Choo, Q.L.2    Del Ninno, E.3
  • 30
    • 0026599783 scopus 로고
    • Hepatitis C virus infection as a risk factor for hepatocellulr carcinoma in patients with cirrhosis. A case-control study
    • Simonetti RG, Cammá C, Fiorello F, et al. Hepatitis C virus infection as a risk factor for hepatocellulr carcinoma in patients with cirrhosis. A case-control study. Ann Intern Med 1992; 2: 97-102
    • (1992) Ann Intern Med , vol.2 , pp. 97-102
    • Simonetti, R.G.1    Cammá, C.2    Fiorello, F.3
  • 31
    • 0030020455 scopus 로고    scopus 로고
    • Alpha interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis
    • Mazzella G, Accogli E, Sottili S, et al. Alpha interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis. J Hepatol 1996; 24 (2): 141-7
    • (1996) J Hepatol , vol.24 , Issue.2 , pp. 141-147
    • Mazzella, G.1    Accogli, E.2    Sottili, S.3
  • 32
    • 0030811412 scopus 로고    scopus 로고
    • Current therapeutic trends for chronic viral hepatitis
    • Liaw Y-F. Current therapeutic trends for chronic viral hepatitis. J Gastroenterol Hepatol 1997; 12: S346-53
    • (1997) J Gastroenterol Hepatol , vol.12
    • Liaw, Y.-F.1
  • 33
    • 6844247656 scopus 로고    scopus 로고
    • Natural lymphoblastoid Wellferon in the prevention of hepatocellular carcinoma in high-risk (HBsAg) positive carriers: A 5-year follow-up
    • Apr 21-25; Rome
    • Oon J-C. Tan N, Lim GK. Natural lymphoblastoid Wellferon in the prevention of hepatocellular carcinoma in high-risk (HBsAg) positive carriers: A 5-year follow-up [abstract]. IXth Triennial International Symposium on viral hepatitis and liver disease; 1996 Apr 21-25; Rome. B32
    • (1996) IXth Triennial International Symposium on Viral Hepatitis and Liver Disease
    • Oon, J.-C.1    Tan, N.2    Lim, G.K.3
  • 34
    • 0026541875 scopus 로고
    • Long-term survival following treatment of hepatocellular carcinoma in Singapore: Evaluation of Wellferon in the prophylaxis of high-risk pre-cancerous conditions
    • Oon J-C. Long-term survival following treatment of hepatocellular carcinoma in Singapore: evaluation of Wellferon in the prophylaxis of high-risk pre-cancerous conditions. Cancer Chemother Pharmacol 1992;31 Suppl.: S137-142
    • (1992) Cancer Chemother Pharmacol , vol.31 , Issue.SUPPL.
    • Oon, J.-C.1
  • 35
    • 0019791877 scopus 로고
    • Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma
    • Shafritz DA, Shouval D, Sherman HI, et al. Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. N Engl J Med 1981; 305 (18): 1067-73
    • (1981) N Engl J Med , vol.305 , Issue.18 , pp. 1067-1073
    • Shafritz, D.A.1    Shouval, D.2    Sherman, H.I.3
  • 36
    • 0028876371 scopus 로고
    • Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis
    • Oct 21
    • Nishiguchi S, Kuroki T, Nakatani S, et al. Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet 1995 Oct 21; 346: 1051-5
    • (1995) Lancet , vol.346 , pp. 1051-1055
    • Nishiguchi, S.1    Kuroki, T.2    Nakatani, S.3
  • 37
    • 0027999941 scopus 로고
    • Prevalence of chronic liver disease in the general population of Northern Italy: The Dionysos Study
    • Bellentani S, Tiribelli C, Saccoccio G, et al. Prevalence of chronic liver disease in the general population of Northern Italy: The Dionysos Study. Hepatology 1994; 20: 1442-9
    • (1994) Hepatology , vol.20 , pp. 1442-1449
    • Bellentani, S.1    Tiribelli, C.2    Saccoccio, G.3
  • 38
    • 9044230923 scopus 로고    scopus 로고
    • Antibodies to interferon (IFN) in hepatitis C patients relapsing while continuing recombinant IFN-α2 therapy
    • Antonelli G. Giannelli G, Currenti M, et al. Antibodies to interferon (IFN) in hepatitis C patients relapsing while continuing recombinant IFN-α2 therapy. Clin Exp Immunol 1996; 104: 384-7
    • (1996) Clin Exp Immunol , vol.104 , pp. 384-387
    • Antonelli, G.1    Giannelli, G.2    Currenti, M.3
  • 39
    • 0029156661 scopus 로고
    • The differential effects of three forms of interferon alfa on hepatic regeneration after partial hepatectomy in the rat
    • Sep
    • Wong S, Gauthier T, Kaita KDE, et al. The differential effects of three forms of interferon alfa on hepatic regeneration after partial hepatectomy in the rat. Hepalology 1995 Sep: 22: 883-6
    • (1995) Hepalology , vol.22 , pp. 883-886
    • Wong, S.1    Gauthier, T.2    Kaita, K.D.E.3
  • 40
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Jan 30
    • Hoofnagle JH, Di BAM. The treatment of chronic viral hepatitis. N Engl J Med 1997 Jan 30; 336: 347-56
    • (1997) N Engl J Med , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1    Di, B.A.M.2
  • 41
    • 0028235641 scopus 로고
    • Classification of chronic hepatitis: Diagnosis, grading and staging
    • Desmet V, Gerber M. Hoofnagle JH, et al. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19: 1513-20
    • (1994) Hepatology , vol.19 , pp. 1513-1520
    • Desmet, V.1    Gerber, M.2    Hoofnagle, J.H.3
  • 42
    • 0031042035 scopus 로고    scopus 로고
    • Interferon alfa in the treatment of chronic viral hepatitis B and C
    • Mar
    • Woo MH, Burnakis TG. Interferon alfa in the treatment of chronic viral hepatitis B and C. Ann Pharmacother 1997 Mar; 31 (3): 330-7
    • (1997) Ann Pharmacother , vol.31 , Issue.3 , pp. 330-337
    • Woo, M.H.1    Burnakis, T.G.2
  • 43
    • 0028347933 scopus 로고
    • Beneficial effect of prednisolone withdrawal followed by human lymphoblastoid interferon on the treatment of chronic type B hepatitis in Asians: A randomized controlled trial
    • Feb
    • Liaw Y-F, Lin S-M, Chen T-J, et al. Beneficial effect of prednisolone withdrawal followed by human lymphoblastoid interferon on the treatment of chronic type B hepatitis in Asians: a randomized controlled trial. J Hepatol 1994 Feb; 20: 175-80
    • (1994) J Hepatol , vol.20 , pp. 175-180
    • Liaw, Y.-F.1    Lin, S.-M.2    Chen, T.-J.3
  • 44
    • 0024973625 scopus 로고
    • Treatment of chronic hepatitis B with lymphoblastoid alpha interferon
    • Castilla A. Civeira MP, Jáuregui JL, et al. Treatment of chronic hepatitis B with lymphoblastoid alpha interferon [in Spanish]. Med Clin 1989; 93 (16): 601-3
    • (1989) Med Clin , vol.93 , Issue.16 , pp. 601-603
    • Castilla, A.1    Civeira, M.P.2    Jáuregui, J.L.3
  • 45
    • 0026514922 scopus 로고
    • A randomized controlled trial of lymphoblastoid interferon-alpha in patients with chronic hepatitiis-B lacking HBeAg
    • Apr
    • Fattovich G, Farci P, Rugge M, et al. A randomized controlled trial of lymphoblastoid interferon-alpha in patients with chronic hepatitiis-B lacking HBeAg. Hepatology 1992 Apr; 15: 584-9
    • (1992) Hepatology , vol.15 , pp. 584-589
    • Fattovich, G.1    Farci, P.2    Rugge, M.3
  • 46
    • 0024359014 scopus 로고
    • A controlled trial of human lymphoblastoid imerferon in chronic hepatitis B in ltaly
    • Saracco G, Muzzella G, Rusina F, et al. A controlled trial of human lymphoblastoid imerferon in chronic hepatitis B in ltaly. Hepatology 1989; 10 (3): 336-41
    • (1989) Hepatology , vol.10 , Issue.3 , pp. 336-341
    • Saracco, G.1    Muzzella, G.2    Rusina, F.3
  • 47
    • 0028813488 scopus 로고
    • Interferon alfa treatment of chronic hepatitis B: Randomized tial in a predominantly homosexual male populalion
    • Jan
    • Wong DKH, Yim C, Naylor CD, et al. Interferon alfa treatment of chronic hepatitis B: randomized tial in a predominantly homosexual male populalion. Gastroenterology 1995 Jan; 108: 165-71
    • (1995) Gastroenterology , vol.108 , pp. 165-171
    • Wong, D.K.H.1    Yim, C.2    Naylor, C.D.3
  • 48
    • 0027238124 scopus 로고
    • Interferon-α therapy with and without interferon-α priming in patients with chronic hepatitis B infection
    • Catterall AP, King R, Lau JYN, et al. Interferon-α therapy with and without interferon-α priming in patients with chronic hepatitis B infection. J Antimicrob Chemother 1993; 31 (5): 777-82
    • (1993) J Antimicrob Chemother , vol.31 , Issue.5 , pp. 777-782
    • Catterall, A.P.1    King, R.2    Lau, J.Y.N.3
  • 49
    • 0026463550 scopus 로고
    • Therapy for chronic hepatitis B with lymphoblastoid interferon-α and levamisole
    • Nov
    • Fattovich G, Giustina G, Brollo L, et al. Therapy for chronic hepatitis B with lymphoblastoid interferon-α and levamisole. Hepatology 1992 Nov; 16: 1115-9
    • (1992) Hepatology , vol.16 , pp. 1115-1119
    • Fattovich, G.1    Giustina, G.2    Brollo, L.3
  • 50
    • 0027414206 scopus 로고
    • Interferon-α and zidovudine combination therapy for chronic hepatitis B: Results of a randomized. placebo-controlled trial
    • Mar
    • Janssen HLA, Berk L, Heijtink RA. Interferon-α and zidovudine combination therapy for chronic hepatitis B: results of a randomized. placebo-controlled trial. Hepatology 1993 Mar; 17: 383-8
    • (1993) Hepatology , vol.17 , pp. 383-388
    • Janssen, H.L.A.1    Berk, L.2    Heijtink, R.A.3
  • 51
    • 10144262545 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis B (HBeAg-HBV DNA-positive) with lymphoblastoid alpha interferon with or without corticosteroids: Shortand long-term follow-up
    • Zavaglia C, Botelli R, Bellati G, et al. Treatment of chronic hepatitis B (HBeAg-HBV DNA-positive) with lymphoblastoid alpha interferon with or without corticosteroids: shortand long-term follow-up. Ital J Gastroenterol 1996; 28 (6): 324-31
    • (1996) Ital J Gastroenterol , vol.28 , Issue.6 , pp. 324-331
    • Zavaglia, C.1    Botelli, R.2    Bellati, G.3
  • 52
    • 0027033289 scopus 로고
    • Randomized controlled trial of alpha-interferon (Wellferon) alone or following prednisone withdrawal in chronic hepatitis B - Results of a multicenter, double blind study
    • Dec
    • Cianciara J, Gladysz A, Juszczyk J, et al. Randomized controlled trial of alpha-interferon (Wellferon) alone or following prednisone withdrawal in chronic hepatitis B - results of a multicenter, double blind study [in Polish]. Pol Arch Med Wewn 1992 Dec; 88: 430-40
    • (1992) Pol Arch Med Wewn , vol.88 , pp. 430-440
    • Cianciara, J.1    Gladysz, A.2    Juszczyk, J.3
  • 53
    • 0029741297 scopus 로고    scopus 로고
    • Interferon vs. adenine arabinoside 5'-monophosphate in patients with anti-HBe-positive chronic hepatitis
    • Buti M, Jardi R, Rodriguez-Frias F. et al. Interferon vs. adenine arabinoside 5'-monophosphate in patients with anti-HBe-positive chronic hepatitis. J Med Virol 1996; 49 (4): 325-8
    • (1996) J Med Virol , vol.49 , Issue.4 , pp. 325-328
    • Buti, M.1    Jardi, R.2    Rodriguez-Frias, F.3
  • 54
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: A meta-analysis
    • Wong DKH, Cheung AM, O'Rourke K, et al. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: a meta-analysis. Ann Intern Med 1993; 119: 312-23
    • (1993) Ann Intern Med , vol.119 , pp. 312-323
    • Wong, D.K.H.1    Cheung, A.M.2    O'Rourke, K.3
  • 55
    • 0025734569 scopus 로고
    • Long-term remission of chronic hepatitis B after alpha-inteferon therapy
    • Korenman J, Baker B, Waggoner J, et al. Long-term remission of chronic hepatitis B after alpha-inteferon therapy. Ann Intern Med 1991; 114 (8): 629-34
    • (1991) Ann Intern Med , vol.114 , Issue.8 , pp. 629-634
    • Korenman, J.1    Baker, B.2    Waggoner, J.3
  • 56
    • 0019409498 scopus 로고
    • Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B
    • Scullard GH, Smith CI, Merigan TC, et al. Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B. Gastroenterology 1981; 81: 987-91
    • (1981) Gastroenterology , vol.81 , pp. 987-991
    • Scullard, G.H.1    Smith, C.I.2    Merigan, T.C.3
  • 57
    • 0018828227 scopus 로고
    • Serum levels of hepatitis B surface and core antigens during immunosuppressive treatment of HBsAg-positive chronic active hepatitis
    • Aug 23
    • Sagnelli E, Manzillo G, Maio G, et al. Serum levels of hepatitis B surface and core antigens during immunosuppressive treatment of HBsAg-positive chronic active hepatitis. Lancet 1980 Aug 23; II: 395-7
    • (1980) Lancet , vol.2 , pp. 395-397
    • Sagnelli, E.1    Manzillo, G.2    Maio, G.3
  • 58
    • 0019979316 scopus 로고
    • The effects of prednisolone/azathioprine in chronic hepatitis B viral infection
    • Weller IVD, Bassendine MF, Murray A, et al. The effects of prednisolone/azathioprine in chronic hepatitis B viral infection, Gut 1982: 650-5
    • (1982) Gut , pp. 650-655
    • Weller, I.V.D.1    Bassendine, M.F.2    Murray, A.3
  • 59
    • 0027944159 scopus 로고
    • Prednisone-interferon combination in the treatment of chronic hepatitis B: Direct and indirect metanalysis
    • Dec
    • Cohard M, Poynard T, Mathurin P, et al. Prednisone-interferon combination in the treatment of chronic hepatitis B: direct and indirect metanalysis. Hepatology 1994 Dec; 20: 1390-8
    • (1994) Hepatology , vol.20 , pp. 1390-1398
    • Cohard, M.1    Poynard, T.2    Mathurin, P.3
  • 60
    • 0024511734 scopus 로고
    • An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis
    • Kuo G, Choo Q-L, Alter HJ, et al. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 1989; 244: 362-4
    • (1989) Science , vol.244 , pp. 362-364
    • Kuo, G.1    Choo, Q.-L.2    Alter, H.J.3
  • 61
    • 14044276377 scopus 로고
    • Hepatitis C: A sleeping giant?
    • Alter MJ, Hepatitis C: a sleeping giant? Am J Med 1991; 91 Suppl. 3B: 112-5S
    • (1991) Am J Med , vol.91 , Issue.SUPPL. 3B
    • Alter, M.J.1
  • 62
    • 0030955346 scopus 로고    scopus 로고
    • Epidemiology of hepatitis C
    • Alter MJ. Epidemiology of hepatitis C. Hepatology 1997; 26 Suppl. 1: 62S-5S
    • (1997) Hepatology , vol.26 , Issue.1 SUPPL.
    • Alter, M.J.1
  • 63
    • 0030885468 scopus 로고    scopus 로고
    • Sexual and perinatal transmission of hepatitis C
    • Dienstag J. Sexual and perinatal transmission of hepatitis C. Hepatology 1997; 26 (3) Suppl. 1: 66S-70S
    • (1997) Hepatology , vol.26 , Issue.3 SUPPL. 1
    • Dienstag, J.1
  • 64
    • 0030928696 scopus 로고    scopus 로고
    • Therapy of hepatitis C: Overview
    • Lindsay KL. Therapy of hepatitis C: overview. Hepatology 1997: 26 Suppl. 1: 71S-7S
    • (1997) Hepatology , vol.26 , Issue.1 SUPPL.
    • Lindsay, K.L.1
  • 66
    • 0027322285 scopus 로고
    • Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C. Effects on inflammation, fibrogenesis and viremia
    • Camps J, Castilla A, Ruiz J, et al. Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C. Effects on inflammation, fibrogenesis and viremia. J Hepatol 1993; 17 (3): 390-6
    • (1993) J Hepatol , vol.17 , Issue.3 , pp. 390-396
    • Camps, J.1    Castilla, A.2    Ruiz, J.3
  • 67
    • 0027489770 scopus 로고
    • Histological outcome of chronic hepatitis C treated with a 12-month course of lymphoblastoid alfa interferon
    • De Alava E, Camps J, Pardo-Mindan J. et al. Histological outcome of chronic hepatitis C treated with a 12-month course of lymphoblastoid alfa interferon. Liver 1993; 13 (2): 73-9
    • (1993) Liver , vol.13 , Issue.2 , pp. 73-79
    • De Alava, E.1    Camps, J.2    Pardo-Mindan, J.3
  • 68
    • 0029912074 scopus 로고    scopus 로고
    • A prospective, randoimized trial comparing lymphoblastoid to recombinant interferon alfa 2a as therapy for chronic hepatitis C
    • Dec
    • Rumi M, Del Ninno E, Parravicini ML, et al. A prospective, randoimized trial comparing lymphoblastoid to recombinant interferon alfa 2a as therapy for chronic hepatitis C. Hepatology 1996 Dec; 24: 1366-70
    • (1996) Hepatology , vol.24 , pp. 1366-1370
    • Rumi, M.1    Del Ninno, E.2    Parravicini, M.L.3
  • 69
    • 0030482377 scopus 로고    scopus 로고
    • Efficacy of ursodeoxycholic acid in combination with interferon-α in treating chronic hepatitis C: Results of a long-term follow-up trial
    • Dec
    • Tanaka K, Kondo M, Sakaguchi T, et al. Efficacy of ursodeoxycholic acid in combination with interferon-α in treating chronic hepatitis C: results of a long-term follow-up trial. J Gastroenterol Hepatol 1996 Dec: 11: 1155-60
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 1155-1160
    • Tanaka, K.1    Kondo, M.2    Sakaguchi, T.3
  • 72
    • 0027534328 scopus 로고    scopus 로고
    • A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C
    • Kagawa T, Morizane T, Saito H, et al. A randomized, controlled trial of weekly administration of lymphoblastoid interferon in patients with chronic hepatitis C. J Hepatol 1997; 17 (I): 91-6
    • (1997) J Hepatol , vol.17 , Issue.1 , pp. 91-96
    • Kagawa, T.1    Morizane, T.2    Saito, H.3
  • 73
    • 0029099105 scopus 로고
    • Interferon may be useful in hemodialysis patients with hepatitis C virus chronic infection who are candidates for kidney transplant
    • Tultavull TC. Baliellas C, Sese E, et al. Interferon may be useful in hemodialysis patients with hepatitis C virus chronic infection who are candidates for kidney transplant. Transplant Proc 1995; 27 (4): 2229-30
    • (1995) Transplant Proc , vol.27 , Issue.4 , pp. 2229-2230
    • Tultavull, T.C.1    Baliellas, C.2    Sese, E.3
  • 74
    • 0030452149 scopus 로고    scopus 로고
    • 1 and lymphoblastoid interferon treatment in chronic hepatitis C
    • Nov
    • 1 and lymphoblastoid interferon treatment in chronic hepatitis C. Gut 1996 Nov; 39: 679-83
    • (1996) Gut , vol.39 , pp. 679-683
    • Rasi, G.1    DiVirgilio, D.2    Mutchnick, M.G.3
  • 75
    • 0025834551 scopus 로고
    • Therapy of chronic hepatitis C and non-A, non-B with alpha -interferon
    • Kamowski B, Hofmann WJ, Otto HF, et al. Therapy of chronic hepatitis C and non-A, non-B with alpha -interferon [in German]. Inn Med 1991; 18 (4): 80-3
    • (1991) Inn Med , vol.18 , Issue.4 , pp. 80-83
    • Kamowski, B.1    Hofmann, W.J.2    Otto, H.F.3
  • 76
    • 0025915674 scopus 로고
    • Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials
    • Tine F, Magrin S, Craxi A, et al. Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomised clinical trials. J Hepatol 1941; 13: 192-9
    • (1941) J Hepatol , vol.13 , pp. 192-199
    • Tine, F.1    Magrin, S.2    Craxi, A.3
  • 77
    • 0029057253 scopus 로고
    • Effect of recombinant or lymphoblastoid interferon-α on alanine aminotransferase in patients with chronic hepatitis C or chronic non-A non-B hepatitis
    • Bardelli F, Messori A, Rampazo R, et al. Effect of recombinant or lymphoblastoid interferon-α on alanine aminotransferase in patients with chronic hepatitis C or chronic non-A non-B hepatitis. Clin Drug Invest 1995; 9 (5): 239-54
    • (1995) Clin Drug Invest , vol.9 , Issue.5 , pp. 239-254
    • Bardelli, F.1    Messori, A.2    Rampazo, R.3
  • 78
    • 0029833829 scopus 로고    scopus 로고
    • Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C: Effects of dose and duration
    • Poynard T, Leroy V, Cohard M, et al. Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C: effects of dose and duration. Hepatology 1996; 24 (4): 77S-89
    • (1996) Hepatology , vol.24 , Issue.4
    • Poynard, T.1    Leroy, V.2    Cohard, M.3
  • 79
    • 0003836107 scopus 로고
    • Lymphoblastoid interferon improves long-term response to a six month course of treatment when compared with recombinant interferon alfa 2b: Results of an international trial
    • Oct
    • Bacon BR, Farrell G, Benhamou JP. Lymphoblastoid interferon improves long-term response to a six month course of treatment when compared with recombinant interferon alfa 2b: results of an international trial [abstract]. Hepatology 1995 Oct: 22 (Pt. 2): 152
    • (1995) Hepatology , vol.22 , Issue.2 PART , pp. 152
    • Bacon, B.R.1    Farrell, G.2    Benhamou, J.P.3
  • 80
    • 6844266942 scopus 로고    scopus 로고
    • Breakthrough and interferon dose in the therapy of chronic hepatitis C
    • Jan
    • Bellati G, Roffi L, Colloredo G, et al. Breakthrough and interferon dose in the therapy of chronic hepatitis C [abstract]. Hepatology 1996 Jan; 23: 1-41
    • (1996) Hepatology , vol.23 , pp. 1-41
    • Bellati, G.1    Roffi, L.2    Colloredo, G.3
  • 81
    • 0029587490 scopus 로고
    • Fate of antibody to Interferon (IFN) in chronic hepatitis C patients treated with recombinant IFN alpha 2 and retreated with lymphoblastoid IFN alpha
    • Dec
    • Antonelli G, Giannelli G, Currenti M, et al. Fate of antibody to Interferon (IFN) in chronic hepatitis C patients treated with recombinant IFN alpha 2 and retreated with lymphoblastoid IFN alpha. Int Hepatol Commun 1995 Dec; 4: 232-7
    • (1995) Int Hepatol Commun , vol.4 , pp. 232-237
    • Antonelli, G.1    Giannelli, G.2    Currenti, M.3
  • 82
    • 0029160074 scopus 로고
    • Treatment with natural IFN of hepatitis C patients with or without antibodies to recombinant IFN
    • Milella M, Antonelli G, Santantonio T, et al. Treatment with natural IFN of hepatitis C patients with or without antibodies to recombinant IFN. Hepatogastroenterology 1995; 42 (3): 201-4
    • (1995) Hepatogastroenterology , vol.42 , Issue.3 , pp. 201-204
    • Milella, M.1    Antonelli, G.2    Santantonio, T.3
  • 83
    • 6844224200 scopus 로고
    • Prevalence of breakthrough during alpha interferon therapy for chronic hepatitis C
    • Oct
    • Bellati G, Collnredo MG, Roffi L, et al. Prevalence of breakthrough during alpha interferon therapy for chronic hepatitis C [abstract]. Hepatology 1994 Oct; 20 (Pt 2): 331A
    • (1994) Hepatology , vol.20 , Issue.2 PART
    • Bellati, G.1    Collnredo, M.G.2    Roffi, L.3
  • 84
    • 6844231431 scopus 로고
    • Prevalence of breakthrough in chronic hepatitis C during alpha interferon therapy
    • May-Jun
    • Colloredo G, Bellati G, Roffi L, et al. Prevalence of breakthrough in chronic hepatitis C during alpha interferon therapy [abstract]. J Gastroenterol Hepatol 1994 May-Jun; 9: A41
    • (1994) J Gastroenterol Hepatol , vol.9
    • Colloredo, G.1    Bellati, G.2    Roffi, L.3
  • 85
    • 0031054021 scopus 로고    scopus 로고
    • Prevalence of breakthrough in chronic hepatitis C patients undergoing antiviral therapy: Role of type and schedule of alpha interferon
    • Feb
    • Bellati G, Colloredo G, Roffi L, et al. Prevalence of breakthrough in chronic hepatitis C patients undergoing antiviral therapy: role of type and schedule of alpha interferon. J Hepatol 1997 Feb; 26: 449-50
    • (1997) J Hepatol , vol.26 , pp. 449-450
    • Bellati, G.1    Colloredo, G.2    Roffi, L.3
  • 86
    • 0028936256 scopus 로고
    • Breakthrough during recombinant interferon alfa therapy in patients with chronic hepatitis C virus infection: Prevalence, etiology and management
    • Roffi L, Colloredo Mels G, Antonelli G, et al. Breakthrough during recombinant interferon alfa therapy in patients with chronic hepatitis C virus infection: prevalence, etiology and management. Hepatology 1995; 21 Suppl. 3: 645-9
    • (1995) Hepatology , vol.21 , Issue.3 SUPPL. , pp. 645-649
    • Roffi, L.1    Colloredo Mels, G.2    Antonelli, G.3
  • 87
    • 0026550304 scopus 로고
    • Lymphoblastoid interferon in chronic hepatitis C patients, 'non-responders' to recombinant interferon-α (rIFN-α)
    • Cimino L, Citarella C, Nardone G, et al. Lymphoblastoid interferon in chronic hepatitis C patients, 'non-responders' to recombinant interferon-α (rIFN-α). J Hepatol 1992; 14 (2-3): 419-20
    • (1992) J Hepatol , vol.14 , Issue.2-3 , pp. 419-420
    • Cimino, L.1    Citarella, C.2    Nardone, G.3
  • 88
    • 6844227623 scopus 로고
    • Lymphoblastoid interferon (IFN) in anti-HCV positive chronic hepatitis unaffected by other interferons
    • Ajello A, Freni MA, Spadaro A, et al. Lymphoblastoid interferon (IFN) in anti-HCV positive chronic hepatitis unaffected by other interferons [abstract]. J Hepatol 1993; 18 Suppl. 1: S87-8
    • (1993) J Hepatol , vol.18 , Issue.1 SUPPL.
    • Ajello, A.1    Freni, M.A.2    Spadaro, A.3
  • 89
    • 0021824119 scopus 로고
    • Treatment of hepatocellular carcinomas with recombinant leukocyte interferon: A pilot study
    • Sachs F, Di Bisceglie AM, Dusheiko GM, et al. Treatment of hepatocellular carcinomas with recombinant leukocyte interferon: A pilot study. Br J Cancer 1985; 52: 105-9
    • (1985) Br J Cancer , vol.52 , pp. 105-109
    • Sachs, F.1    Di Bisceglie, A.M.2    Dusheiko, G.M.3
  • 90
    • 0022479153 scopus 로고
    • The use of interferon functional assays in the laboratory monitoring of patients with hepatocellular carcinoma receiving interferon
    • Lyons SF, Schoub BD, Kew MC, et al. The use of interferon functional assays in the laboratory monitoring of patients with hepatocellular carcinoma receiving interferon. Am J Clin Pathol 1986; 85: 450-5
    • (1986) Am J Clin Pathol , vol.85 , pp. 450-455
    • Lyons, S.F.1    Schoub, B.D.2    Kew, M.C.3
  • 91
    • 0028839782 scopus 로고
    • The long-term efficacy of interferon alfa in chronic hepatitis C palients: A critical review
    • Nov-Dec
    • Saracco G, Rizzetto M. The long-term efficacy of interferon alfa in chronic hepatitis C palients: a critical review. J Gastroenterol Hepatol 1995 Nov-Dec; 10: 668-73
    • (1995) J Gastroenterol Hepatol , vol.10 , pp. 668-673
    • Saracco, G.1    Rizzetto, M.2
  • 92
    • 0028146380 scopus 로고
    • Prediction of sustained remission of chronic hepatitis C after a 12-month course of alfa interferon
    • Camps J, Garcia-Grancro M, Riezu-Boj JI, et al. Prediction of sustained remission of chronic hepatitis C after a 12-month course of alfa interferon. J Hepatol 1994; 21 (1): 4-11
    • (1994) J Hepatol , vol.21 , Issue.1 , pp. 4-11
    • Camps, J.1    Garcia-Grancro, M.2    Riezu-Boj, J.I.3
  • 93
    • 0029084933 scopus 로고
    • Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors of sustained response to interferon alfa therapy in chronic hepatitis C
    • Martinot-Peignoux M, Marcellin P, Pouteau M, et al. Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors of sustained response to interferon alfa therapy in chronic hepatitis C. Hepalology 1995; 22 (4): 1050-6
    • (1995) Hepalology , vol.22 , Issue.4 , pp. 1050-1056
    • Martinot-Peignoux, M.1    Marcellin, P.2    Pouteau, M.3
  • 94
    • 6844226529 scopus 로고
    • HCV genotypes and viremia in predicting response to interferon alfa in chronic hepatitis C
    • Oct
    • Hermida M, Castro A, Calvo SL, et al. HCV genotypes and viremia in predicting response to interferon alfa in chronic hepatitis C [abstract]. Hepatology 1995 Oct; 22 Pt 2: 428A
    • (1995) Hepatology , vol.22 , Issue.2 PART
    • Hermida, M.1    Castro, A.2    Calvo, S.L.3
  • 95
    • 0030885469 scopus 로고    scopus 로고
    • Factors predictive of a beneficial response to therapy of hepatitis C
    • Davis GL, Lau JYN. Factors predictive of a beneficial response to therapy of hepatitis C. Hepatology 1997; 26 Suppl. 1: 122S-7S
    • (1997) Hepatology , vol.26 , Issue.1 SUPPL.
    • Davis, G.L.1    Lau, J.Y.N.2
  • 96
    • 0022991958 scopus 로고
    • Lymphoblastoid and recombinant α-A interferon therapy of chronic hepatitis B virus infection. The Royal Free Hospital experience
    • 2
    • Thomas HC, Scully LJ, McDonald JA. Lymphoblastoid and recombinant α-A interferon therapy of chronic hepatitis B virus infection. The Royal Free Hospital experience. J Hepatol 1986; 3 Suppl. (5) 2: S193-7
    • (1986) J Hepatol , vol.3 , Issue.5 SUPPL.
    • Thomas, H.C.1    Scully, L.J.2    McDonald, J.A.3
  • 97
    • 0029815925 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C with interferon alpha: Long-term follow-up and prognostic relevance of HCV genotypes
    • Hopf U, Berg T, König V, et al. Treatment of chronic hepatitis C with interferon alpha: long-term follow-up and prognostic relevance of HCV genotypes. J Hepatol 1996; 24 Suppl. 2: 67-73
    • (1996) J Hepatol , vol.24 , Issue.2 SUPPL. , pp. 67-73
    • Hopf, U.1    Berg, T.2    König, V.3
  • 98
    • 0027385541 scopus 로고
    • Prediction of the response of chronic hepatitis C to interferon alfa: A statistical analysis of pretreatment variables
    • Camps J, Crisóstomo S, García-Granero M, et al. Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables. Gut 1993; 34 (12): 1714-7
    • (1993) Gut , vol.34 , Issue.12 , pp. 1714-1717
    • Camps, J.1    Crisóstomo, S.2    García-Granero, M.3
  • 99
    • 0028331837 scopus 로고
    • Interferon- alpha for chronic hepatitis C: An analysis of pretreatment clinical predictors of response
    • Pugliaro L, Craxi A, Cammaa C. et al. Interferon- alpha for chronic hepatitis C: an analysis of pretreatment clinical predictors of response. Hepatology 1994; 19(4): 820-8
    • (1994) Hepatology , vol.19 , Issue.4 , pp. 820-828
    • Pugliaro, L.1    Craxi, A.2    Cammaa, C.3
  • 100
    • 8244248790 scopus 로고    scopus 로고
    • Liver iron influ-ences the response to Interferon alpha therapy in chronic hepatitis C
    • Fargion S, Fracanzani AL, Sampietro M. et al. Liver iron influ-ences the response to Interferon alpha therapy in chronic hepatitis C. Eur J Gastroenterol Hepatol 1997; 9: 497-503
    • (1997) Eur J Gastroenterol Hepatol , vol.9 , pp. 497-503
    • Fargion, S.1    Fracanzani, A.L.2    Sampietro, M.3
  • 101
    • 0025222056 scopus 로고
    • Immunological studies before and during Interferon therapy in chronic HBV infection: Identification of factors predicting response
    • Scully LJ, Brown D, Lloyd C et al. Immunological studies before and during Interferon therapy in chronic HBV infection: identification of factors predicting response. Hepalology 1990; 12 (5): 1111-7
    • (1990) Hepalology , vol.12 , Issue.5 , pp. 1111-1117
    • Scully, L.J.1    Brown, D.2    Lloyd, C.3
  • 102
    • 0029066449 scopus 로고
    • T-lymphocyte subpopulations as factors predicting clinical response to interferon in hepatitis C virus-related chronic active hepatitis [2]
    • Guadagnino V, Caroleo B, Izzi A, et al. T-lymphocyte subpopulations as factors predicting clinical response to interferon in hepatitis C virus-related chronic active hepatitis [2]. Infection 1995; 23(3): 189-90
    • (1995) Infection , vol.23 , Issue.3 , pp. 189-190
    • Guadagnino, V.1    Caroleo, B.2    Izzi, A.3
  • 103
    • 0028256163 scopus 로고
    • Treatment of chronic sporadic-type non-A. non-B hepatitis with lymphoblastoid Interferon: Gamma GT levels predictive for response
    • Mazzella G, Salzetta A, Casanova S, et al. Treatment of chronic sporadic-type non-A. non-B hepatitis with lymphoblastoid Interferon: gamma GT levels predictive for response. Dig Dis Sci 1994; 39(4): 866-70
    • (1994) Dig Dis Sci , vol.39 , Issue.4 , pp. 866-870
    • Mazzella, G.1    Salzetta, A.2    Casanova, S.3
  • 104
    • 6844263668 scopus 로고    scopus 로고
    • Randomized controlled trial of lymphoblastoid Interferon α for chrome hepatitis C (comparions of 6 MU versus 9 MU dosages): Early disappearance of HCV RNA is essential for sustained response. American Association for the Study of Liver Diseases
    • Nov 7-11; Chicago
    • Yoshioka K, Yano M, Terazawa Y, et al. Randomized controlled trial of lymphoblastoid Interferon α for chrome hepatitis C (comparions of 6 MU versus 9 MU dosages): early disappearance of HCV RNA is essential for sustained response. American Association for the Study of Liver Diseases. Postgraduate Courses and 48th Annual Meeting. 1997 Nov 7-11; Chicago, 421A
    • (1997) Postgraduate Courses and 48th Annual Meeting
    • Yoshioka, K.1    Yano, M.2    Terazawa, Y.3
  • 105
    • 0027370657 scopus 로고
    • Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: Different patterns of response to interferon treatment
    • Gil B, Qian C, Riezu-Boj JI, et al. Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: different patterns of response to interferon treatment. Hepatology 1993; 18 (5): 1050-4
    • (1993) Hepatology , vol.18 , Issue.5 , pp. 1050-1054
    • Gil, B.1    Qian, C.2    Riezu-Boj, J.I.3
  • 106
    • 0028971824 scopus 로고
    • Risks and benefits of interferon-α in the treatment of hepatitis
    • Nov
    • Pardo M, Marriott E, Moliner MC, et al. Risks and benefits of interferon-α in the treatment of hepatitis. Drug Saf 1995 Nov; 13: 304-16
    • (1995) Drug Saf , vol.13 , pp. 304-316
    • Pardo, M.1    Marriott, E.2    Moliner, M.C.3
  • 107
    • 6844224155 scopus 로고    scopus 로고
    • Adverse effects in hepatitis B and C treated with interferon. Any difference?
    • Oct; Program Suppl
    • Marinho R, Serejo F, Raimundo M, et al. Adverse effects in hepatitis B and C treated with interferon. Any difference? [abstract]. Hepatology 1996 Oct; 24 Pt 2: Program Suppl: 543
    • (1996) Hepatology , vol.24 , Issue.2 PART , pp. 543
    • Marinho, R.1    Serejo, F.2    Raimundo, M.3
  • 108
    • 0024221988 scopus 로고
    • Treatment of chronic hepatitis B with human lymphoblastoid interferon: Results of a controlled trial
    • Dec
    • Mazzella G, Villanova N, Abdu-Ahmed M, et al. Treatment of chronic hepatitis B with human lymphoblastoid interferon: results of a controlled trial [in English]. Chemioterapia 1988 Dec; 7 Suppl. 3: 12-4
    • (1988) Chemioterapia , vol.7 , Issue.3 SUPPL. , pp. 12-14
    • Mazzella, G.1    Villanova, N.2    Abdu-Ahmed, M.3
  • 109
    • 0026642892 scopus 로고
    • Antiviral effect of prolonged intermittent lymphoblastoid alpha interferon treatment in chronic hepatitis B
    • Aug
    • Janssen HLA, Berk L, Schalm SW, et al. Antiviral effect of prolonged intermittent lymphoblastoid alpha interferon treatment in chronic hepatitis B. Gut 1992 Aug; 33: 1094-8
    • (1992) Gut , vol.33 , pp. 1094-1098
    • Janssen, H.L.A.1    Berk, L.2    Schalm, S.W.3
  • 110
    • 0028885030 scopus 로고
    • Interferon-α-2a: A review of its pharmacological properties and therapeutic use in the management of viral hepatitis
    • Nov
    • Haria M, Benfield P. Interferon-α-2a: a review of its pharmacological properties and therapeutic use in the management of viral hepatitis. Drugs 1995 Nov; 50: 873-96
    • (1995) Drugs , vol.50 , pp. 873-896
    • Haria, M.1    Benfield, P.2
  • 112
    • 0029793436 scopus 로고    scopus 로고
    • Interferon-α therapy may induce insulin autoantibody development in patients with chronic viral hepatitis
    • Di Cesare E, Previti M, Russo F, et al. Interferon-α therapy may induce insulin autoantibody development in patients with chronic viral hepatitis. Dig bis Sci 1996; 41 (8): 1672-7
    • (1996) Dig Bis Sci , vol.41 , Issue.8 , pp. 1672-1677
    • Di Cesare, E.1    Previti, M.2    Russo, F.3
  • 113
    • 0028919930 scopus 로고
    • Hepatitis C virus infection. alpha interferon therapy and thyroid dysfunction
    • Mar
    • Marcellin P, Pouteau M, Benhamou J-P. Hepatitis C virus infection. alpha interferon therapy and thyroid dysfunction. J Hepatol 1995 Mar; 22: 364-9
    • (1995) J Hepatol , vol.22 , pp. 364-369
    • Marcellin, P.1    Pouteau, M.2    Benhamou, J.-P.3
  • 114
    • 0026604957 scopus 로고
    • Development of thyroid disease during therapy of chronic viral hepatitis with interferon alfa
    • Lisker-Melman M, Di Bisceglie AM, Usala SJ, et al. Development of thyroid disease during therapy of chronic viral hepatitis with interferon alfa. Gastroenterology 1992; 102 (6): 2155-60
    • (1992) Gastroenterology , vol.102 , Issue.6 , pp. 2155-2160
    • Lisker-Melman, M.1    Di Bisceglie, A.M.2    Usala, S.J.3
  • 115
    • 0030845861 scopus 로고    scopus 로고
    • Prospective study on thyroid autoimmunity and dysfunction related to chronic hepatitis C and interferon therapy
    • Custro N, Montalto G, Scafidi V, et al. Prospective study on thyroid autoimmunity and dysfunction related to chronic hepatitis C and interferon therapy. J Endocrinol Invest 1997; 20: 374-80
    • (1997) J Endocrinol Invest , vol.20 , pp. 374-380
    • Custro, N.1    Montalto, G.2    Scafidi, V.3
  • 116
    • 6844244847 scopus 로고
    • Organ specific autoantibodies in patients with chronic hepatitis treated with Interferon
    • Sonnante AM, Cozzolongo R, Ragnini F, et al. Organ specific autoantibodies in patients with chronic hepatitis treated with Interferon (abstract). Gut 1995; 37 Suppl. 2: A234-235
    • (1995) Gut , vol.37 , Issue.2 SUPPL.
    • Sonnante, A.M.1    Cozzolongo, R.2    Ragnini, F.3
  • 117
    • 0029955576 scopus 로고    scopus 로고
    • Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon-α therapy
    • Marazuela M, Garcia-Buey L, Gonzaiez-Fernandez B, et al. Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon-α therapy. Clin Endocrinol 1996; 44 (6): 635-42
    • (1996) Clin Endocrinol , vol.44 , Issue.6 , pp. 635-642
    • Marazuela, M.1    Garcia-Buey, L.2    Gonzaiez-Fernandez, B.3
  • 118
    • 0027417622 scopus 로고
    • Interferon in the management of chronic hepatitis B
    • Perillo RP. Interferon in the management of chronic hepatitis B. Dig Dis Sci 1993; 38: 577-93
    • (1993) Dig Dis Sci , vol.38 , pp. 577-593
    • Perillo, R.P.1
  • 119
    • 0030886964 scopus 로고    scopus 로고
    • National Institutes of Health Consensus Development Conference Panel Statement: Management of hepatitis C
    • National Institutes of Health. National Institutes of Health Consensus Development Conference Panel Statement: management of hepatitis C. Hepatology 1997; 26 (3) Suppl. 1: 2S-10S
    • (1997) Hepatology , vol.26 , Issue.3 SUPPL. 1
  • 120
    • 0030955347 scopus 로고    scopus 로고
    • Therapy of hepatitis C: Patients with cirrhosis
    • Schalm SW, Fattovich G, Brouwer JT. Therapy of hepatitis C: patients with cirrhosis. Hepatology 1997; 26 (3): 128S-32S
    • (1997) Hepatology , vol.26 , Issue.3
    • Schalm, S.W.1    Fattovich, G.2    Brouwer, J.T.3
  • 121
    • 0028016286 scopus 로고
    • The epidemiology of viral hepatitis in the United States
    • Alter MJ, Mast EE. The epidemiology of viral hepatitis in the United States. Gastroenterol Clin N Am 1994; 23: 437-55
    • (1994) Gastroenterol Clin N Am , vol.23 , pp. 437-455
    • Alter, M.J.1    Mast, E.E.2
  • 122
    • 0028950003 scopus 로고
    • Understanding hepatitis B infection
    • Moradpour D, Wands JR. Understanding hepatitis B infection. N Engl J Med 1995; 332: 1092-3
    • (1995) N Engl J Med , vol.332 , pp. 1092-1093
    • Moradpour, D.1    Wands, J.R.2
  • 124
    • 0026320833 scopus 로고
    • Long-term clinical and histopathological follow-up of chronic posttransfusion hepatitis
    • Di Bisceglie AM, Goodman ZD, Ishak KG, et al. Long-term clinical and histopathological follow-up of chronic posttransfusion hepatitis. Hepatology 1991; 14: 969-74
    • (1991) Hepatology , vol.14 , pp. 969-974
    • Di Bisceglie, A.M.1    Goodman, Z.D.2    Ishak, K.G.3
  • 125
    • 0028998145 scopus 로고
    • Clinical outocmes after transfusion-associated hepatitis
    • Tong MJ, El-Farra NS, et al. Clinical outocmes after transfusion-associated hepatitis. N Engl J Med 1995; 332: 1464-6
    • (1995) N Engl J Med , vol.332 , pp. 1464-1466
    • Tong, M.J.1    El-Farra, N.S.2
  • 126
    • 0025990116 scopus 로고
    • Descartes before the horse: I clone, therefore I am: the hepatitis C virus in current perspective
    • Alter HJ. Descartes before the horse: I clone, therefore I am: the hepatitis C virus in current perspective. Ann Intern Med 1991; 115: 644-9
    • (1991) Ann Intern Med , vol.115 , pp. 644-649
    • Alter, H.J.1
  • 127
    • 0031021442 scopus 로고    scopus 로고
    • Vaccines to prevent viral hepatitis
    • Jan 16
    • Lemon SM, Thomas DL. Vaccines to prevent viral hepatitis. N Engl J Med 1997 Jan 16; 336: 196-203
    • (1997) N Engl J Med , vol.336 , pp. 196-203
    • Lemon, S.M.1    Thomas, D.L.2
  • 128
    • 0030048114 scopus 로고    scopus 로고
    • A rational approach to the management of hepatitis C infection
    • Feb 10
    • Dusheiko GM, Khakoo S, Soni P, et al. A rational approach to the management of hepatitis C infection. BMJ 1996 Feb 10; 312: 357-64
    • (1996) BMJ , vol.312 , pp. 357-364
    • Dusheiko, G.M.1    Khakoo, S.2    Soni, P.3
  • 129
    • 0028905697 scopus 로고
    • Development of antiviral therapy with alpha interferons: Promises, false hopes and accomplishments
    • Feb
    • Cantell K. Development of antiviral therapy with alpha interferons: promises, false hopes and accomplishments. Ann Med 1995 Feb; 27: 23-8
    • (1995) Ann Med , vol.27 , pp. 23-28
    • Cantell, K.1
  • 130
    • 0031029317 scopus 로고    scopus 로고
    • A practical guide to the use of interferons in the management of hepatitis virus infectious
    • Jan
    • Saracco G, Rizzetto M. A practical guide to the use of interferons in the management of hepatitis virus infectious. Drugs 1997 Jan; 53: 74-85
    • (1997) Drugs , vol.53 , pp. 74-85
    • Saracco, G.1    Rizzetto, M.2
  • 131
    • 0029759886 scopus 로고    scopus 로고
    • New treatments for chronic viral hepatitis B and C
    • Jul
    • Dusheiko GM. New treatments for chronic viral hepatitis B and C. Baillieres Clin Gastroenterol 1996 Jul; 10: 299-333
    • (1996) Baillieres Clin Gastroenterol , vol.10 , pp. 299-333
    • Dusheiko, G.M.1
  • 132
    • 0028236954 scopus 로고
    • Prostaglandin e plus lamciclovir - A new concept for the treatment of severe hepatitis B after liver transplantation
    • Böker KH, Ringe B, Krüger M, et al. Prostaglandin E plus lamciclovir - a new concept for the treatment of severe hepatitis B after liver transplantation. Transplantation 1994; 57: 1706-8
    • (1994) Transplantation , vol.57 , pp. 1706-1708
    • Böker, K.H.1    Ringe, B.2    Krüger, M.3
  • 133
    • 0026058540 scopus 로고
    • Inhibition of the replication of hepatitis B virus in vitro by 2'3'-dideoxy-3'-thiacytidine and related analogues
    • Doong S-L, Tsai C-H, Schinazi.RF, et al. Inhibition of the replication of hepatitis B virus in vitro by 2'3'-dideoxy-3'-thiacytidine and related analogues. Proc Natl Acad Sci U S A 1991; 88: 8495-9
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 8495-8499
    • Doong, S.-L.1    Tsai, C.-H.2    Schinazi, R.F.3
  • 134
    • 0029591574 scopus 로고
    • A preliminary trial of lamivudine for chronic hepatitis B infection
    • Dienstag JL, Perrillo RP, Schiff HR, et al. A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med 1995; 133: 1657-61
    • (1995) N Engl J Med , vol.133 , pp. 1657-1661
    • Dienstag, J.L.1    Perrillo, R.P.2    Schiff, H.R.3
  • 135
    • 0000071445 scopus 로고    scopus 로고
    • Extended lamivudine retreatment for chronic hepatitis B
    • Dienstag JL, Schilf ER, Gitlin N, et al. Extended lamivudine retreatment for chronic hepatitis B. Hepatology 1996; 24 Suppl. 188A
    • (1996) Hepatology , vol.24 , Issue.SUPPL.
    • Dienstag, J.L.1    Schilf, E.R.2    Gitlin, N.3
  • 136
    • 6844228684 scopus 로고    scopus 로고
    • Lamivudine plus interferon for the treatment of IFN-nonresponsive chronic hepatitis C infection. American Association for the study of Liver Diseases
    • [abstract]: Nov 7-11; Chicago
    • Kania RJ, Friedlander L, Van Thiel DH, et al. Lamivudine plus interferon for the treatment of IFN-nonresponsive chronic hepatitis C infection. American Association for the study of Liver Diseases; Postgraduate Courses and 48th Annual Meeting [abstract]: 1997 Nov 7-11; Chicago. 1626.
    • (1997) Postgraduate Courses and 48th Annual Meeting , pp. 1626
    • Kania, R.J.1    Friedlander, L.2    Van Thiel, D.H.3
  • 137
    • 0029824574 scopus 로고    scopus 로고
    • Pathophysiology and treatment of hepatitis C
    • Thomas HC, Booth J, Brown J. Pathophysiology and treatment of hepatitis C. Drugs 1996; 52 Suppl. 2: 1-8
    • (1996) Drugs , vol.52 , Issue.2 SUPPL. , pp. 1-8
    • Thomas, H.C.1    Booth, J.2    Brown, J.3
  • 138
    • 6844225203 scopus 로고    scopus 로고
    • Randomised trial in HBeAg negative patients with replicating virus with lamivudine or ganciclovir in combination with interferon. Preliminary data
    • Pt 2, Oct
    • Alexopoulou A, Papakonstntinou A, Zafiropoulou E, et al. Randomised trial in HBeAg negative patients with replicating virus with lamivudine or ganciclovir in combination with interferon. Preliminary data. Hepatology 26 (Suppl.): Pt 2, Oct 1997
    • (1997) Hepatology , vol.26 , Issue.SUPPL.
    • Alexopoulou, A.1    Papakonstntinou, A.2    Zafiropoulou, E.3
  • 139
    • 0030457708 scopus 로고    scopus 로고
    • Current perspectives on the treatment and prevention of hepatitis C infection
    • Dec
    • Blair CS, Haydon GH, Hayes PC. Current perspectives on the treatment and prevention of hepatitis C infection. Expert Opin Invest Drug 1996 Dec; 5: 1657-71
    • (1996) Expert Opin Invest Drug , vol.5 , pp. 1657-1671
    • Blair, C.S.1    Haydon, G.H.2    Hayes, P.C.3
  • 140
    • 0030060114 scopus 로고    scopus 로고
    • Hepatitis C: A clinical update
    • Jan
    • Colquhoun SD. Hepatitis C: a clinical update. Arch Surg 1996 Jan; 131: 18-23
    • (1996) Arch Surg , vol.131 , pp. 18-23
    • Colquhoun, S.D.1
  • 141
    • 9244231148 scopus 로고    scopus 로고
    • Lymphoblastoid interferon alfa with of without steroid pretreatment in children with chronic hepatitis B: A multicenter controlled trial
    • Apr
    • Gregorio GV, Jara P, Hierro L, et al. Lymphoblastoid interferon alfa with of without steroid pretreatment in children with chronic hepatitis B: a multicenter controlled trial. Hepatology 1996 Apr; 23: 700-7
    • (1996) Hepatology , vol.23 , pp. 700-707
    • Gregorio, G.V.1    Jara, P.2    Hierro, L.3
  • 142
    • 0024238053 scopus 로고
    • Treatment of children with chronic hepatitis B with a combination of steroids and human lymphoblastoid interferon
    • Dec
    • Giacchino R, Facco F, Giambartolomei G. et al. Treatment of children with chronic hepatitis B with a combination of steroids and human lymphoblastoid interferon. Chemioterapia 1988 Dec: 7 Suppl. 3: 20-5
    • (1988) Chemioterapia , vol.7 , Issue.3 SUPPL. , pp. 20-25
    • Giacchino, R.1    Facco, F.2    Giambartolomei, G.3
  • 143
    • 0024466080 scopus 로고
    • Treatment of chronic hepatitis delta virus (HDV) infeclion with human lymphoblastoid alpha interferon
    • Farci P, Karayiannis P, Brook MG, et al. Treatment of chronic hepatitis delta virus (HDV) infeclion with human lymphoblastoid alpha interferon. Q J Med 1989; 73 (271): 1045-54
    • (1989) Q J Med , vol.73 , Issue.271 , pp. 1045-1054
    • Farci, P.1    Karayiannis, P.2    Brook, M.G.3
  • 144
    • 0026558169 scopus 로고
    • Treatment of early chronic delta hepatitis with lymphoblastoid alpha interferon: A pilot study
    • Marzano A, Ottobrelli A, Spezia C, et al. Treatment of early chronic delta hepatitis with lymphoblastoid alpha interferon: A pilot study, Ital J Gastroenterol 1992; 24 (3): 119-21
    • (1992) Ital J Gastroenterol , vol.24 , Issue.3 , pp. 119-121
    • Marzano, A.1    Ottobrelli, A.2    Spezia, C.3


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